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List of works by Richard Oreffo

* The Chorioallantoic Membrane Assay for Biomaterial Testing in Tissue Engineering: A Short-Term In Vivo Preclinical Model.

scientific article published on 6 September 2017

3D human bone marrow stromal and endothelial cell spheres promote bone healing in an osteogenic niche

scientific article published on 07 November 2018

A Novel Approach for Studying the Temporal Modulation of Embryonic Skeletal Development Using Organotypic Bone Cultures and Microcomputed Tomography ⬇️

scientific article published on May 21, 2012

A blueprint for translational regenerative medicine

scientific article published on 01 December 2020

A comparison of polymer and polymer-hydroxyapatite composite tissue engineered scaffolds for use in bone regeneration. An in vitro and in vivo study

scientific article published on 5 September 2013

A genomics approach in determining nanotopographical effects on MSC phenotype ⬇️

scientific article published on January 9, 2013

A microarray approach to the identification of polyurethanes for the isolation of human skeletal progenitor cells and augmentation of skeletal cell growth

scientific article

A new take on an old story: chick limb organ culture for skeletal niche development and regenerative medicine evaluation.

scientific article published on 11 September 2013

A review of hydrogel use in fracture healing and bone regeneration.

scientific article published on 10 December 2014

A surprisingly poor correlation between in vitro and in vivo testing of biomaterials for bone regeneration: results of a multicentre analysis.

scientific article published on 24 May 2016

A tissue engineering strategy for the treatment of avascular necrosis of the femoral head

scientific article published on 27 March 2013

Absence of the lysophosphatidic acid receptor LPA1 results in abnormal bone development and decreased bone mass.

scientific article published on May 2011

Acoustically modulated biomechanical stimulation for human cartilage tissue engineering.

scientific article published on 4 January 2018

Activation of the bone-derived latent TGF beta complex by isolated osteoclasts

scientific article published in February 1989

Adipocyte differentiation induced using nonspecific siRNA controls in cultured human mesenchymal stem cells.

scientific article published on 07 June 2007

Adult mesenchymal stem cells and impaction grafting: a new clinical paradigm shift

scientific article published on May 2007

Alternative and complementary therapies in osteoarthritis and cartilage repair

scientific article published on 13 March 2020

An analysis of polymer type and chain length for use as a biological composite graft extender in impaction bone grafting: A mechanical and biocompatibility study

scientific article published on 15 June 2012

An ex vivo model for chondrogenesis and osteogenesis

scientific article published on 23 March 2007

Angiogenic Potential of Human Neonatal Foreskin Stromal Cells in the Chick Embryo Chorioallantoic Membrane Model.

scientific article published on 29 June 2015

Animal models of maternal nutrition and altered offspring bone structure--bone development across the lifecourse.

scientific article

Application of 3D-printed patient-specific skeletal implants augmented with autologous skeletal stem cells

scientific article published on 01 April 2018

Application of an acoustofluidic perfusion bioreactor for cartilage tissue engineering

scientific article

Assays for bone resorption and bone formation

scientific article published in 1991

Assessing the potential of colony morphology for dissecting the CFU-F population from human bone marrow stromal cells

scientific article published on 9 February 2013

Association between the abnormal expression of matrix-degrading enzymes by human osteoarthritic chondrocytes and demethylation of specific CpG sites in the promoter regions.

scientific article

Association of reduced type IX collagen gene expression in human osteoarthritic chondrocytes with epigenetic silencing by DNA hypermethylation

scientific article

Augmentation of skeletal tissue formation in impaction bone grafting using vaterite microsphere biocomposites

scientific article published on 9 January 2009

Biocompatibility and osteogenic potential of human fetal femur-derived cells on surface selective laser sintered scaffolds

scientific article

Biofabrication of bone tissue: approaches, challenges and translation for bone regeneration.

scientific article

Biological and mechanical enhancement of impacted allograft seeded with human bone marrow stromal cells: potential clinical role in impaction bone grafting

scientific article published in July 2006

Biomimetic oyster shell-replicated topography alters the behaviour of human skeletal stem cells

scientific article published on 01 January 2018

Bisphosphonate nanoclay edge-site interactions facilitate hydrogel self-assembly and sustained growth factor localization

scientific article published on 13 March 2020

Bone Tissue Engineering

scientific article

Bone and metal: an orthopaedic perspective on osseointegration of metals

scientific article

Bone induction at physiological doses of BMP through localization by clay nanoparticle gels.

scientific article published on 10 May 2016

Bone tissue engineering: hope vs hype

scientific article

Bridging the gap.

scientific article

Bridging the regeneration gap: stem cells, biomaterials and clinical translation in bone tissue engineering.

scientific article published on 26 March 2008

Cells cultured from the growing tip of red deer antler express alkaline phosphatase and proliferate in response to insulin-like growth factor-I.

scientific article

Centre for human development, stem cells & regeneration

scientific article published on January 2014

Changes in the antiangiogenic properties of articular cartilage in osteoarthritis

scientific article published in January 2003

Characterisation and evaluation of the regenerative capacity of Stro-4+ enriched bone marrow mesenchymal stromal cells using bovine extracellular matrix hydrogel and a novel biocompatible melt electro-written medical-grade polycaprolactone scaffold

scientific article published on 01 April 2020

Characterisation of human bone marrow stromal cell heterogeneity for skeletal regeneration strategies using a two-stage colony assay and computational modelling.

scientific article

Characterization and multipotentiality of human fetal femur-derived cells: implications for skeletal tissue regeneration

scientific article published on 22 December 2005

Characterization of New PEEK/HA Composites with 3D HA Network Fabricated by Extrusion Freeforming

scientific article published on 26 May 2016

Characterization of a cell line derived from a human giant cell tumor that stimulates osteoclastic bone resorption.

scientific article published on November 1993

Characterization of human skeletal stem and bone cell populations using dielectrophoresis.

scientific article published on 6 December 2012

Chondrobags: A high throughput alginate-fibronectin micromass platform for in vitro human cartilage formation

scientific article published on 01 October 2020

Chondrogenic potential of human articular chondrocytes and skeletal stem cells: a comparative study.

scientific article published on 20 August 2014

Clay gels for the delivery of regenerative microenvironments.

scientific article published on 10 June 2011

Clay: new opportunities for tissue regeneration and biomaterial design

scientific article published on 31 May 2013

Cold water cleaning of brain proteins, biofilm and bone - harnessing an ultrasonically activated stream

scientific article published on 22 July 2015

Computational modelling of cell spreading and tissue regeneration in porous scaffolds.

scientific article published on 18 December 2006

Concise review: bridging the gap: bone regeneration using skeletal stem cell-based strategies - where are we now?

scientific article published on January 2014

Controlled differentiation of human bone marrow stromal cells using magnetic nanoparticle technology.

scientific article published in October 2010

DNA methylation of the RUNX2 P1 promoter mediates MMP13 transcription in chondrocytes

scientific article published on 10 August 2017

Delivery systems for bone growth factors - the new players in skeletal regeneration.

scientific article published on April 2004

Demethylation of an NF-κB enhancer element orchestrates iNOS induction in osteoarthritis and is associated with altered chondrocyte cell cycle

scientific article published on 12 June 2016

Derivation of a novel undifferentiated human foetal phenotype in serum-free cultures with BMP-2.

scientific article

Development of a clay based bioink for 3D cell printing for skeletal application.

scientific article published on 10 July 2017

Development of a slow non-viral DNA release system from PDLLA scaffolds fabricated using a supercritical CO2 technique

scientific article published in October 2007

Development of in vivo muCT evaluation of neovascularisation in tissue engineered bone constructs

scientific article published on 5 March 2008

Development of protocols for the first serial block-face scanning electron microscopy (SBF SEM) studies of bone tissue

scientific article published on 24 October 2019

Development of specific collagen scaffolds to support the osteogenic and chondrogenic differentiation of human bone marrow stromal cells

scientific article published on 28 April 2008

Developmental Cues for Bone Formation from Parathyroid Hormone and Parathyroid Hormone-Related Protein in anEx VivoOrganotypic Culture System of Embryonic Chick Femora ⬇️

scientific article published on September 13, 2012

Developmental plasticity of human foetal femur-derived cells in pellet culture: self assembly of an osteoid shell around a cartilaginous core

scientific article

Differential in-gel electrophoresis (DIGE) analysis of human bone marrow osteoprogenitor cell contact guidance

scientific article published on 27 November 2008

Disordered protein-graphene oxide co-assembly and supramolecular biofabrication of functional fluidic devices

scientific article published on 04 March 2020

Dynamic Surfaces for the Study of Mesenchymal Stem Cell Growth through Adhesion Regulation

scientific article published on 20 June 2016

EFFECTS OF BETA MERCAPTOETHANOL ON THE PROLIFERATION AND DIFFERENTIATION OF HUMAN OSTEOPROGENITOR CELLS

scientific article published in July 1997

Effect of vitamin D deficiency during pregnancy on offspring bone structure, composition and quality in later life.

scientific article

Effect of vitamin a on bone resorption: Evidence for direct stimulation of isolated chicken osteoclasts by retinol and retinoic acid

scientific article published on 3 December 2009

Effects of Novel Calcium Phosphate Cements on Human Bone Marrow Fibroblastic Cells

scientific article published in September 1998

Effects of Setting Bone Cement on Tissue-Engineered Bone Graft

scientific article published on 01 April 2013

Effects of TGFβ and BFGF on the differentiation of human bone marrow stromal fibroblasts

scientific article published in March 1999

Effects of a surface topography composite with puerariae radix on human STRO-1-positive stem cells

scientific article published on 17 March 2010

Effects of hypothyroidism on the structure and mechanical properties of bone in the ovine fetus

scientific article published on 3 June 2011

Effects of hypoxia on anabolic and catabolic gene expression and DNA methylation in OA chondrocytes

scientific article

Effects of interferon alpha on human osteoprogenitor cell growth and differentiation in vitro

scientific article published on 01 September 1999

Embossing of micropatterned ceramics and their cellular response

scientific article published on 3 April 2013

Embryonic and induced pluripotent stem cells: understanding, creating, and exploiting the nano-niche for regenerative medicine.

scientific article published on 15 February 2013

Enhancing the osteogenic efficacy of human bone marrow aspirate: concentrating osteoprogenitors using wave-assisted filtration.

scientific article published on 12 December 2012

Epigenetic modifiers influence lineage commitment of human bone marrow stromal cells: Differential effects of 5-aza-deoxycytidine and trichostatin A.

scientific article published in January 2011

Epigenetic regulation during fetal femur development: DNA methylation matters.

scientific article

Epigenetic regulation of interleukin-8, an inflammatory chemokine, in osteoarthritis

scientific article

Epithelial mechanobiology, skin wound healing, and the stem cell niche

scientific article

Evaluation of human bone marrow stromal cell growth on biodegradable polymer/bioglass composites

scientific article published on 17 February 2006

Evaluation of skeletal tissue repair, part 1: assessment of novel growth-factor-releasing hydrogels in an ex vivo chick femur defect model

scientific article published on 14 June 2014

Evaluation of skeletal tissue repair, part 2: enhancement of skeletal tissue repair through dual-growth-factor-releasing hydrogels within an ex vivo chick femur defect model

scientific article published on 4 June 2014

Expansion of human bone marrow stromal cells on poly-(DL-lactide-co-glycolide) (PDL LGA) hollow fibres designed for use in skeletal tissue engineering.

scientific article

Experimental characterization and computational modelling of two-dimensional cell spreading for skeletal regeneration.

scientific article published on December 2007

Experimental-computational evaluation of human bone marrow stromal cell spreading on trabecular bone structures.

scientific article published on 19 March 2009

Exploratory Full-Field Strain Analysis of Regenerated Bone Tissue from Osteoinductive Biomaterials

scientific article published on 01 January 2020

Extracellular Matrix Deposition in Engineered Micromass Cartilage Pellet Cultures: Measurements and Modelling

scientific article published on 18 February 2016

Fabrication of hydroxyapatite sponges by dextran sulphate/amino acid templating.

scientific article published on November 2005

Fabrication of pillar-like titania nanostructures on titanium and their interactions with human skeletal stem cells

scientific article published on 21 January 2009

Formation of a human-derived fat tissue layer in P(DL)LGA hollow fibre scaffolds for adipocyte tissue engineering

scientific article published on 9 January 2009

From bench to clinic and back: skeletal stem cells and impaction bone grafting for regeneration of bone defects

scientific article published on 5 October 2012

Future potentials for using osteogenic stem cells and biomaterials in orthopedics.

scientific article

Gelatin Methacryloyl Hydrogels for Musculoskeletal Tissue Regeneration

scientific article published on 21 July 2022

Gene therapy used for tissue engineering applications.

scientific article published on March 2007

Genetic manipulation of human mesenchymal progenitors to promote chondrogenesis using "bead-in-bead" polysaccharide capsules

scientific article published on 25 September 2007

Growth and differentiation of human bone marrow osteoprogenitors on novel calcium phosphate cements

scientific article published in October 1998

Growth factors for skeletal reconstruction and fracture repair.

scientific article published on April 2004

Harnessing Human Decellularized Blood Vessel Matrices and Cellular Construct Implants to Promote Bone Healing in an Ex Vivo Organotypic Bone Defect Model

scientific article published on 14 May 2018

Harnessing Nanotopography to Enhance Osseointegration of Clinical Orthopedic Titanium Implants-An in Vitro and in Vivo Analysis.

scientific article

Harnessing nanotopography and integrin-matrix interactions to influence stem cell fate

scientific article published on June 2014

High-resolution 3D imaging of osteocytes and computational modelling in mechanobiology: insights on bone development, ageing, health and disease.

scientific article published on 22 May 2016

Hope versus hype: what can additive manufacturing realistically offer trauma and orthopedic surgery?

scientific article

Human Skeletal Stem Cell Response to Multiscale Topography Induced by Large Area Electron Beam Irradiation Surface Treatment

scientific article published on 24 July 2018

Human endothelial and foetal femur-derived stem cell co-cultures modulate osteogenesis and angiogenesis.

scientific article

Human fibroblast and human bone marrow cell response to lithographically nanopatterned adhesive domains on protein rejecting substrates

scientific article published in September 2007

Human mesenchymal factors induce rat hippocampal- and human neural stem cell dependent oligodendrogenesis

scientific article

Human osteoprogenitor bone formation using encapsulated bone morphogenetic protein 2 in porous polymer scaffolds

scientific article published in July 2004

Human osteoprogenitor growth and differentiation on synthetic biodegradable structures after surface modification

scientific article published in December 2001

Hydroxyapatite coated with insulin-like growth factor 1 (IGF1) stimulates human osteoblast activity in vitro

scientific article published in January 1999

Hypoxia inducible factors regulate pluripotency and proliferation in human embryonic stem cells cultured at reduced oxygen tensions

scientific article published on January 2010

Identification of candidate regulators of multipotency in human skeletal progenitor cells.

scientific article published on 26 September 2008

Immunoselection and adenoviral genetic modulation of human osteoprogenitors: in vivo bone formation on PLA scaffold

scientific article published in November 2002

Impact of inflammation on the osteoarthritic niche: implications for regenerative medicine.

scientific article published on July 2012

In Vivo Assessment of Bone Regeneration in Alginate/Bone ECM Hydrogels with Incorporated Skeletal Stem Cells and Single Growth Factors

scientific article published on 16 December 2015

In search of the skeletal stem cell: isolation and separation strategies at the macro/micro scale for skeletal regeneration

scientific article published on 25 February 2011

In vitro and in vivo methods to determine the interactions of osteogenic cells with biomaterials

scientific article published in 1999

In vivo delivery of VEGF RNA and protein to increase osteogenesis and intraosseous angiogenesis

scientific article published on 28 November 2019

Inhibition of Hydroxyapatite Nanoparticle-Induced Osteogenic Activity in Skeletal Cells by Adsorption of Serum Proteins

scientific article published on 18 August 2010

Inhibition of bone resorption by inorganic phosphate is mediated by both reduced osteoclast formation and decreased activity of mature osteoclasts

scientific article published in May 1991

Inhibitory effects of the bone-derived growth factors osteoinductive factor and transforming growth factor-beta on isolated osteoclasts.

scientific article published in June 1990

Interactions with nanoscale topography: adhesion quantification and signal transduction in cells of osteogenic and multipotent lineage

scientific article published in October 2009

Interconversion potential of cloned human marrow adipocytes in vitro

scientific article published in June 1999

Intrauterine programming of bone. Part 1: alteration of the osteogenic environment

scientific article published on 15 August 2007

Intrauterine programming of bone. Part 2: alteration of skeletal structure

scientific article published on 18 August 2007

Isolation and Enrichment of Stro-1 Immunoselected Mesenchymal Stem Cells from Adult Human Bone Marrow

scientific article published in 2013

Isolation, Differentiation, and Characterization of Human Bone Marrow Stem Cells In Vitro and In Vivo

scientific article published on 01 January 2019

Isolation, differentiation, and characterisation of skeletal stem cells from human bone marrow in vitro and in vivo.

scientific article published in January 2012

Label-free enrichment of primary human skeletal progenitor cells using deterministic lateral displacement

scientific article published on 01 January 2019

Large animal in vivo evaluation of a binary blend polymer scaffold for skeletal tissue-engineering strategies; translational issues.

scientific article published on 18 February 2015

Live-imaging of Bioengineered Cartilage Tissue using Multimodal Non-linear Molecular Imaging

scientific article published on 03 April 2019

Local Variation in Femoral Neck Cortical Bone: In Vitro Measured Bone Mineral Density, Geometry and Mechanical Properties.

scientific article published on 17 December 2015

Loss of methylation in CpG sites in the NF-κB enhancer elements of inducible nitric oxide synthase is responsible for gene induction in human articular chondrocytes.

scientific article published on March 2013

MODULATION OF OSTEOGENIC DIFFERENTIATION IN HUMAN SKELETAL CELLS IN VITRO BY 5-AZACYTIDINE

scientific article published in March 1998

MagicWand: a single, designed peptide that assembles to stable, ordered alpha-helical fibers.

scientific article

Mammalian cell survival and processing in supercritical CO(2)

scholarly article

Maternal High Fat Diet Affects Offspring's Vitamin K-Dependent Proteins Expression Levels.

scientific article published on 18 September 2015

Maternal high-fat diet and offspring expression levels of vitamin K-dependent proteins

scientific article published on 3 October 2014

Maternal high-fat diet: effects on offspring bone structure.

scientific article published on 21 November 2009

Maternal protein deficiency affects mesenchymal stem cell activity in the developing offspring

scientific article published in July 2003

Mathematical modelling of skeletal repair.

scientific article published on January 2004

Mesenchymal Stem Cells: Potential Role in the Treatment of Osteochondral Lesions of the Ankle.

scientific article published on 25 October 2017

Metabolomics: a valuable tool for stem cell monitoring in regenerative medicine ⬇️

scientific article published on May 23, 2012

MiR-146b is down-regulated during the chondrogenic differentiation of human bone marrow derived skeletal stem cells and up-regulated in osteoarthritis.

scientific article

MicroRNA-146a regulates human foetal femur derived skeletal stem cell differentiation by down-regulating SMAD2 and SMAD3.

scientific article

Mineralized polysaccharide capsules as biomimetic microenvironments for cell, gene and growth factor delivery in tissue engineering

scientific article published in 2006

Modulation of bone morphogenetic protein-2 and bone morphogenetic protein-4 gene expression in osteoblastic cell lines

scientific article published in December 1998

Modulation of osteogenesis and adipogenesis by human serum in human bone marrow cultures

scientific article published in November 1997

Nanoclay-based 3D printed scaffolds promote vascular ingrowth <i>ex vivo</i> and generate bone mineral tissue <i>in vitro</i> and <i>in vivo</i>

scientific article published on 07 April 2020

Nanoscale surfaces for the long-term maintenance of mesenchymal stem cell phenotype and multipotency

scientific article published on 17 July 2011

Nanotopographical Effects on Mesenchymal Stem Cell Morphology and Phenotype

scientific article published on 13 December 2013

Nanotopographical control of human osteoprogenitor differentiation

scientific article published on May 2007

Nanotopographical control of stem cell differentiation.

scientific article

Nanotopographical cues augment mesenchymal differentiation of human embryonic stem cells.

scientific article

Nanotopography controls cell cycle changes involved with skeletal stem cell self-renewal and multipotency.

scientific article published on 24 November 2016

Natural marine sponge fiber skeleton: a biomimetic scaffold for human osteoprogenitor cell attachment, growth, and differentiation.

scientific article published in December 2003

Osteoarthritis treatment with a novel nutraceutical acetylated ligstroside aglycone, a chemically modified extra-virgin olive oil polyphenol

scientific article published on 01 January 2020

Osteogenic and angiogenic tissue formation in high fidelity nanocomposite Laponite-gelatin bioinks

scientific article published on 12 June 2019

Osteogenic lineage restriction by osteoprogenitors cultured on nanometric grooved surfaces: the role of focal adhesion maturation

scientific article

Osteogenic stem-cell characterization and development: potentials for cytotherapy.

scientific article

Osteonecrosis following treatment for childhood acute lymphoblastic leukaemia: The Southampton Children's Hospital experience.

scientific article published in December 2017

Osteoprogenitor response to defined topographies with nanoscale depths

scientific article published on 6 September 2005

Osteoprogenitor response to low-adhesion nanotopographies originally fabricated by electron beam lithography

scientific article published on 3 February 2007

Osteoprogenitor response to semi-ordered and random nanotopographies

scientific article published on 27 January 2006

PEGylated liposomes associate with Wnt3A protein and expand putative stem cells in human bone marrow populations

scientific article published on 29 March 2017

Patients with primary osteoarthritis show no change with ageing in the number of osteogenic precursors

scientific article published in January 1998

Perfusion bioreactor studies of chondrocyte growth in alginate-chitosan capsules.

scientific article published on March 2012

Pleiotrophin/Osteoblast-stimulating factor 1: dissecting its diverse functions in bone formation.

scientific article

Polymersome nanoparticles for delivery of Wnt-activating small molecules

scientific article published on 17 March 2018

Preservation and stability of cell therapy products: recommendations from an expert workshop.

scientific article published on 19 July 2017

Printing bone in a gel: using nanocomposite bioink to print functionalised bone scaffolds

scientific article published on 01 September 2019

Prospective isolation of human bone marrow stromal cell subsets: A comparative study between Stro-1-, CD146- and CD105-enriched populations

scientific article

Proteomic analysis of human osteoprogenitor response to disordered nanotopography.

scientific article published on 9 December 2008

Quality of life in sarcopenia and frailty

scientific article published on 05 July 2013

Quantification of intracellular payload release from polymersome nanoparticles.

scientific article

Quantifying intracortical bone microstructure: A critical appraisal of 2D and 3D approaches for assessing vascular canals and osteocyte lacunae

scientific article published on 08 October 2020

Raman spectroscopy and coherent anti-Stokes Raman scattering imaging: prospective tools for monitoring skeletal cells and skeletal regeneration

scientific article

Regenerative medicine in lower limb reconstruction

scientific article published on 01 June 2018

Regionally-derived cell populations and skeletal stem cells from human foetal femora exhibit specific osteochondral and multi-lineage differentiation capacity in vitro and ex vivo

scientific article

Regulated transcription of human matrix metalloproteinase 13 (MMP13) and interleukin-1β (IL1B) genes in chondrocytes depends on methylation of specific proximal promoter CpG sites

scientific article published on 15 February 2013

Regulation of osteoblast development by Bcl-2-associated athanogene-1 (BAG-1)

scientific article

Regulation of the Bone Vascular Network is Sexually Dimorphic

scientific article published on 09 October 2019

Remodelling of human bone on the chorioallantoic membrane of the chicken egg: De novo bone formation and resorption

scientific article published in August 2018

Repositioning Titanium: An In Vitro Evaluation of Laser-Generated Microporous, Microrough Titanium Templates As a Potential Bridging Interface for Enhanced Osseointegration and Durability of Implants.

scientific article published on 11 December 2017

Self-Assembling Nanoclay Diffusion Gels for Bioactive Osteogenic Microenvironments

scientific article published on 17 June 2018

Sex- and bone-specific responses in bone structure to exogenous leptin and leptin receptor antagonism in the ovine fetus

scientific article published on 14 February 2018

Site-Dependent Reference Point Microindentation Complements Clinical Measures for Improved Fracture Risk Assessment at the Human Femoral Neck.

scientific article published on August 2015

Size and dielectric properties of skeletal stem cells change critically after enrichment and expansion from human bone marrow: consequences for microfluidic cell sorting.

scientific article published on August 2017

Skeletal progenitor cells and ageing human populations

scientific article

Skeletal stem cell and bone implant interactions are enhanced by LASER titanium modification.

scientific article published on 8 October 2015

Skeletal stem cell isolation: A review on the state-of-the-art microfluidic label-free sorting techniques.

scientific article published on 25 May 2016

Skeletal stem cell physiology on functionally distinct titania nanotopographies

scientific article published in October 2011

Skeletal stem cells and bone regeneration: translational strategies from bench to clinic.

scientific article published on December 2010

Skeletal stem cells: phenotype, biology and environmental niches informing tissue regeneration.

scientific article published on 04 March 2008

Skeletal tissue regeneration: current approaches, challenges, and novel reconstructive strategies for an aging population

scientific article published on 30 June 2011

Spina bifida-predisposing heterozygous mutations in Planar Cell Polarity genes and Zic2 reduce bone mass in young mice.

scientific article published on 20 February 2018

Stochasticity and the molecular mechanisms of induced pluripotency

scientific article

Strategies for cell manipulation and skeletal tissue engineering using high-throughput polymer blend formulation and microarray techniques

scientific article published in March 2010

Strategies to promote chondrogenesis and osteogenesis from human bone marrow cells and articular chondrocytes encapsulated in polysaccharide templates.

scientific article published in October 2006

Supercritical CO2 fluid-foaming of polymers to increase porosity: a method to improve the mechanical and biocompatibility characteristics for use as a potential alternative to allografts in impaction bone grafting?

scientific article published on 24 January 2012

Supercritical carbon dioxide generated vascular endothelial growth factor encapsulated poly(DL-lactic acid) scaffolds induce angiogenesis in vitro

scientific article published on 9 November 2006

Suppressors of cytokine signalling (SOCS) are reduced in osteoarthritis.

scientific article published on 23 February 2011

Surface mobility regulates skeletal stem cell differentiation

scientific article published on 6 March 2012

Taking tissue engineering principles into theatre: retrieval analysis from a clinically translated case.

scientific article published in July 2011

Taking tissue-engineering principles into theater: augmentation of impacted allograft with human bone marrow stromal cells

scientific article published in September 2006

Temporal analysis of rat growth plates: cessation of growth with age despite presence of a physis.

scientific article

The Potential of microRNAs for Stem Cell-based Therapy for Degenerative Skeletal Diseases.

scientific article published on 23 October 2017

The application of human bone marrow stromal cells and poly(dl-lactic acid) as a biological bone graft extender in impaction bone grafting.

scientific article published on 5 May 2008

The cell in the ink: Improving biofabrication by printing stem cells for skeletal regenerative medicine

scientific article published on 14 April 2019

The chorioallantoic membrane (CAM) assay for the study of human bone regeneration: a refinement animal model for tissue engineering.

scientific article

The effect of anisotropic architecture on cell and tissue infiltration into tissue engineering scaffolds.

scientific article published in September 2006

The effect of mesenchymal populations and vascular endothelial growth factor delivered from biodegradable polymer scaffolds on bone formation.

scientific article

The effect of oxygen tension on human articular chondrocyte matrix synthesis: integration of experimental and computational approaches.

scientific article

The effect of porosity of a biphasic ceramic scaffold on human skeletal stem cell growth and differentiation in vivo

scientific article published on 9 April 2013

The effect of pre-coating human bone marrow stromal cells with hydroxyapatite/amino acid nanoconjugates on osteogenesis.

scientific article published on 6 March 2009

The effect of the delivery of vascular endothelial growth factor and bone morphogenic protein-2 to osteoprogenitor cell populations on bone formation

scientific article published on 18 November 2009

The effects of 1α, 25-dihydroxyvitamin D3 and transforming growth factor-β3 on bone development in an ex vivo organotypic culture system of embryonic chick femora

scientific article published on 2 April 2015

The epigenetic effect of glucosamine and a nuclear factor-kappa B (NF-kB) inhibitor on primary human chondrocytes--implications for osteoarthritis

scientific article

The inferomedial femoral neck is compromised by age but not disease: Fracture toughness and the multifactorial mechanisms comprising reference point microindentation

scientific article published on 30 June 2017

The influence of a high fat diet on bone and soft tissue formation in Matrix Gla Protein knockout mice.

scientific article published on 26 February 2018

The interaction of human bone marrow cells with nanotopographical features in three dimensional constructs

scientific article published in November 2006

The potential of biomimesis in bone tissue engineering: lessons from the design and synthesis of invertebrate skeletons.

scientific article

The role of osteoblast cells in the pathogenesis of unicameral bone cysts

scientific article

The role of vibration and drainage in femoral impaction bone grafting.

scientific article

The scale-up of a tissue engineered porous hydroxyapatite polymer composite scaffold for use in bone repair: An ovine femoral condyle defect study

scientific article published on 23 July 2014

The use of nanoscale topography to modulate the dynamics of adhesion formation in primary osteoblasts and ERK/MAPK signalling in STRO-1+ enriched skeletal stem cells.

scientific article published on 21 June 2009

The use of small interfering RNAs to inhibit adipocyte differentiation in human preadipocytes and fetal-femur-derived mesenchymal cells

scientific article published on 17 April 2006

Tissue engineered bone using select growth factors: A comprehensive review of animal studies and clinical translation studies in man.

scientific article published on 06 October 2014

Tissue engineering strategies for cartilage generation--micromass and three dimensional cultures using human chondrocytes and a continuous cell line.

scientific article published on July 2005

Tissue engineering strategies in spinal arthrodesis: the clinical imperative and challenges to clinical translation

scientific article published on January 2013

Tracking adipogenic differentiation of skeletal stem cells by label-free chemically selective imaging.

scientific article published on 9 September 2015

Transfer learning efficiently maps bone marrow cell types from mouse to human using single-cell RNA sequencing

scientific article published on 04 December 2020

Transient Canonical Wnt Stimulation Enriches Human Bone Marrow Mononuclear Cell Isolates for Osteoprogenitors

scientific article

Translational hurdles for tissue engineering: an in vitro analysis of commonly used local anaesthetics on skeletal stem cell survival

scientific article

Transplanted human pluripotent stem cell-derived mesenchymal stem cells support liver regeneration in Gunn rats

scientific article published on 20 November 2018

Trapping single human osteoblast-like cells from a heterogeneous population using a dielectrophoretic microfluidic device

scientific article

Using Nanotopography and Metabolomics to Identify Biochemical Effectors of Multipotency

scientific article published on 24 October 2012

Variability in reference point microindentation and recommendations for testing cortical bone: location, thickness and orientation heterogeneity.

scientific article published on 17 February 2015

Variability in reference point microindentation and recommendations for testing cortical bone: maximum load, sample orientation, mode of use, sample preparation and measurement spacing.

scientific article

Versatile Biocompatible Polymer Hydrogels: Scaffolds for Cell Growth

scientific article published on 01 January 2009

Vibration-assisted bone-graft compaction in impaction bone grafting of the femur

article

Whole proteome analysis of osteoprogenitor differentiation induced by disordered nanotopography and mediated by ERK signalling.

scientific article published on 26 June 2009

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