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List of works by Carlo Gabriele Tocchetti

Abnormal glucose transport and GLUT1 cell-surface content in fibroblasts and skeletal muscle from NIDDM and obese subjects.

scientific article published on April 1997

Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart

scientific article published in 2022

Anticancer therapy-induced vascular toxicity: VEGF inhibition and beyond.

scientific article published on 9 November 2016

Antineoplastic Drug-Induced Cardiotoxicity: A Redox Perspective.

scientific article published on 7 March 2018

Bidirectional cross-regulation between ErbB2 and β-adrenergic signalling pathways

scientific article published on 21 December 2015

Biomarkers in sarcopenia: A multifactorial approach.

scientific article published on 12 September 2016

Bmi1 inhibitor PTC-209 promotes Chemically-induced Direct Cardiac Reprogramming of cardiac fibroblasts into cardiomyocytes

scientific article published on 28 April 2020

Calcitonin gene-related peptide in vivo positive inotropy is attributable to regional sympatho-stimulation and is blunted in congestive heart failure

scientific article published on 9 December 2004

Cancer Risk in the Heart Failure Population: Epidemiology, Mechanisms, and Clinical Implications

scientific article published on 02 December 2020

Cardioprotection by gene therapy: A review paper on behalf of the Working Group on Drug Cardiotoxicity and Cardioprotection of the Italian Society of Cardiology.

scientific article published on May 2015

Cardiovascular Toxicity of Immune Checkpoint Inhibitors: Clinical Risk Factors

scientific article published on 07 January 2021

Comparison of hemodynamic adaptation to orthostatic stress in patients with hypertrophic cardiomyopathy with or without syncope and in vasovagal syncope.

scientific article

Comparison of preclinical cardiotoxic effects of different ErbB2 inhibitors.

scientific article published on 27 September 2011

Comparison of the NO and HNO donating properties of diazeniumdiolates: primary amine adducts release HNO in Vivo

scientific article published in December 2005

Compartmentalization of cardiac beta-adrenergic inotropy modulation by phosphodiesterase type 5.

scientific article published on 9 April 2007

Compartmentalized phosphodiesterase-2 activity blunts beta-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway

scientific article published on 15 December 2005

Complete atrioventricular block in a patient with intracardiac metastases from malignant melanoma

scientific article published on 23 June 2011

Constitutive BDNF/TrkB signaling is required for normal cardiac contraction and relaxation.

scientific article

Current views on anthracycline cardiotoxicity.

scientific article published on 26 May 2016

Detection, monitoring, and management of trastuzumab-induced left ventricular dysfunction: an actual challenge.

scientific article published on 04 January 2012

Determinants and clinical significance of natriuretic peptides and hypertrophic cardiomyopathy

scientific article published in August 2001

Determinants of atrial fibrillation development in patients with hypertrophic cardiomyopathy

scientific article published on 01 October 2004

Discriminating formation of HNO from other reactive nitrogen oxide species

scientific article published on 21 November 2005

Dobutamine stress echocardiography in hypertrophic cardiomyopathy

scientific article published in January 2003

Doxorubicin-induced cardiomyopathy: from molecular mechanisms to therapeutic strategies

scientific article published on 21 March 2012

Early identification of left ventricular dysfunction induced by trastuzumab

scientific article published on 01 December 2011

Endogenous Cardioprotective Agents: Role in Pre and Postconditioning

scientific article

GSH or palmitate preserves mitochondrial energetic/redox balance, preventing mechanical dysfunction in metabolically challenged myocytes/hearts from type 2 diabetic mice

scientific article

Glutathione oxidation unmasks proarrhythmic vulnerability of chronically hyperglycemic guinea pigs

scientific article published on February 2013

Hemodynamic effects of isometric exercise in hypertrophic cardiomyopathy: comparison with normal subjects.

scientific article

Impaired mitochondrial energy supply coupled to increased H2O2 emission under energy/redox stress leads to myocardial dysfunction during Type I diabetes.

scientific article

Improving the preclinical models for the study of chemotherapy-induced cardiotoxicity: a Position Paper of the Italian Working Group on Drug Cardiotoxicity and Cardioprotection.

scientific article published on September 2015

Intracardiac metastasis originated from chondrosarcoma

scientific article published on 01 May 2017

Mechanism of aerobic decomposition of Angeli's salt (sodium trioxodinitrate) at physiological pH

scientific article published on 01 January 2005

Metabolic remodelling of glucose, fatty acid and redox pathways in the heart of type 2 diabetic mice

scientific article published on 30 December 2018

Metalloproteinase inhibitor counters high-energy phosphate depletion and AMP deaminase activity enhancing ventricular diastolic compliance in subacute heart failure

scientific article published on 25 January 2006

Mitral peak early diastolic filling velocity to deceleration time ratio as a predictor of prognosis in patients with chronic heart failure and preserved or reduced ejection fraction

scientific article

Models of Heart Failure Based on the Cardiotoxicity of Anticancer Drugs.

scientific article published on 18 April 2016

Modulation of Redox Signaling in Chronic Diseases and Regenerative Medicine

scientific article published on 23 April 2019

Myocardial collagen turnover in hypertrophic cardiomyopathy

scientific article published on 2 September 2003

Nanotechnology-Based Cardiac Targeting and Direct Cardiac Reprogramming: The Betrothed

scientific article

Nitroso-Redox Balance and Modulation of Basal Myocardial Function: An Update from the Italian Society of Cardiovascular Research (SIRC).

scientific article published on 3 March 2015

Nitroxyl (HNO) for treatment of acute heart failure

scientific article published on September 2014

Nitroxyl (HNO) targets phospholamban cysteines 41 and 46 to enhance cardiac function

scientific article published on 06 March 2019

Nitroxyl (HNO): A novel approach for the acute treatment of heart failure

scientific article

Nitroxyl increases force development in rat cardiac muscle

scientific article published on 01 March 2007

Oxidative and nitrosative stress in the maintenance of myocardial function.

scientific article published on 20 July 2012

PDE5A suppression of acute beta-adrenergic activation requires modulation of myocyte beta-3 signaling coupled to PKG-mediated troponin I phosphorylation

scientific article

PED/PEA-15 gene controls glucose transport and is overexpressed in type 2 diabetes mellitus

scientific article

Pathophysiology of anthracycline cardiotoxicity.

scientific article

Peroxynitrite and myocardial contractility: in vivo versus in vitro effects

scientific article published on 05 September 2006

Phosphoinositide 3-Kinase Gamma Inhibition Protects from Anthracycline Cardiotoxicity and Reduces Tumor Growth.

scientific article published on 18 January 2018

Phospholamban thiols play a central role in activation of the cardiac muscle sarcoplasmic reticulum calcium pump by nitroxyl.

scientific article published in December 2008

Playing with cardiac "redox switches": the "HNO way" to modulate cardiac function

scientific article

Preventing antiblastic drug-related cardiomyopathy: old and new therapeutic strategies.

scientific article

Prognostic significance of left atrial volume dilatation in patients with hypertrophic cardiomyopathy

scientific article published in January 2009

Protective mechanisms of mitochondria and heart function in diabetes

scientific article

Pulmonary Hypertension Phenotypes in Systemic Sclerosis: The Right Diagnosis for the Right Treatment

scientific article published on 22 June 2020

Ranolazine protects from doxorubicin-induced oxidative stress and cardiac dysfunction.

scientific article published in April 2014

Recent Advances on Pathophysiology, Diagnostic and Therapeutic Insights in Cardiac Dysfunction Induced by Antineoplastic Drugs

scientific article

Redox Imbalances in Ageing and Metabolic Alterations: Implications in Cancer and Cardiac Diseases. An Overview from the Working Group of Cardiotoxicity and Cardioprotection of the Italian Society of Cardiology (SIC)

scientific article published on 21 July 2020

Restoring redox balance enhances contractility in heart trabeculae from type 2 diabetic rats exposed to high glucose.

scientific article

Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: efficacy of recoupling nitric oxide synthase as a therapeutic strategy

scientific article published on 12 May 2008

Role of preeclampsia-related angiogenic factors in sunitinib cardiotoxicity: two cases and review of the literature

scientific article published on January 2013

Sex differences in anthracycline-induced cardiotoxicity: the benefits of estrogens

scientific article published on 01 November 2019

Targeting myocardial remodelling to develop novel therapies for heart failure: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology

scientific article

Testosterone Antagonizes Doxorubicin-Induced Senescence of Cardiomyocytes.

scientific article published on 8 January 2016

The autonomic nervous system as a therapeutic target in heart failure: a scientific position statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology

scientific article

The chemical dynamics of NO and reactive nitrogen oxides: a practical guide.

scientific article

The novel butyrate derivative phenylalanine-butyramide protects from doxorubicin-induced cardiotoxicity

scientific article published on 06 March 2019

The pharmacology of nitroxyl (HNO) and its therapeutic potential: not just the Janus face of NO

scientific article

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