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List of works by Karen M Dobos

A Subset of Protective γ9δ2 T Cells Is Activated by Novel Mycobacterial Glycolipid Components

scientific article

A chemical proteomics approach to profiling the ATP-binding proteome of Mycobacterium tuberculosis

scientific article published on 5 March 2013

A limited antigen-specific cellular response is sufficient for the early control of Mycobacterium tuberculosis in the lung but is insufficient for long-term survival

scientific article

A murine DC-SIGN homologue contributes to early host defense against Mycobacterium tuberculosis

scientific journal article

Analysis of the metabolome of Anopheles gambiae mosquito after exposure to Mycobacterium ulcerans

scientific article

Antigen 85 variation across lineages of Mycobacterium tuberculosis-implications for vaccine and biomarker success

scientific article published on 24 July 2013

Assessment of vaccine testing at three laboratories using the guinea pig model of tuberculosis

scientific article published on October 2011

Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation

scientific article

Biochemical Characterization of Isoniazid-resistant Can the Analysis of Clonal Strains Reveal Novel Targetable Pathways?

scientific article published on 29 May 2018

Boosting BCG-primed responses with a subunit Apa vaccine during the waning phase improves immunity and imparts protection against Mycobacterium tuberculosis

scientific article

Changes in the Membrane-Associated Proteins of Exosomes Released from Human Macrophages after Mycobacterium tuberculosis Infection

scientific article

Comparing isogenic strains of Beijing genotype Mycobacterium tuberculosis after acquisition of Isoniazid resistance: A proteomics approach

scientific article published on March 2016

Continued proteomic analysis of Mycobacterium leprae subcellular fractions

article

Deciphering the molecular basis of mycobacteria and lipoglycan recognition by the C-type lectin Dectin-2

scientific article published in Scientific Reports

Deciphering the proteome of the in vivo diagnostic reagent "purified protein derivative" from Mycobacterium tuberculosis

scientific article published on April 2012

Deciphering the proteomic profile of Mycobacterium leprae cell envelope

scientific article published on June 2008

Deciphering the role of exosomes in tuberculosis

scientific article

Demonstration of components of antigen 85 complex in cerebrospinal fluid of tuberculous meningitis patients

scientific article

Descriptive proteomic analysis shows protein variability between closely related clinical isolates of Mycobacterium tuberculosis

scientific article published on May 2010

Detection of Mycobacterium tuberculosis peptides in the exosomes of patients with active and latent M. tuberculosis infection using MRM-MS

scientific article

Emergence of a unique group of necrotizing mycobacterial diseases.

scientific article

Epidemiologic consequences of microvariation in Mycobacterium tuberculosis

scientific article

Fractionation and Analysis of Mycobacterial Proteins

article

HspX vaccination and role in virulence in the guinea pig model of tuberculosis

scientific article

HspX-mediated protection against tuberculosis depends on its chaperoning of a mycobacterial molecule

scientific article

IFNgamma response to Mycobacterium tuberculosis, risk of infection and disease in household contacts of tuberculosis patients in Colombia

scientific article

Immunoproteomic identification of human T cell antigens of Mycobacterium tuberculosis that differentiate healthy contacts from tuberculosis patients

scientific article

Longitudinal whole genome analysis of pre and post drug treatment Mycobacterium tuberculosis isolates reveals progressive steps to drug resistance

scientific article published on 26 February 2016

Membrane-Bound PenA β-Lactamase of Burkholderia pseudomallei

scientific article published on 28 December 2015

Mycobacterium ulcerans cytotoxicity in an adipose cell model

scientific article

Necrosis of lung epithelial cells during infection with Mycobacterium tuberculosis is preceded by cell permeation

scientific article published on November 2000

O-mannosylation of the Mycobacterium tuberculosis adhesin Apa is crucial for T cell antigenicity during infection but is expendable for protection

scientific article

Pathogenic nontuberculous mycobacteria resist and inactivate cathelicidin: implication of a novel role for polar mycobacterial lipids

scientific article published on 18 May 2015

Peripheral Blood and Pleural Fluid Mononuclear Cell Responses to Low-Molecular-Mass Secretory Polypeptides of Mycobacterium tuberculosis in Human Models of Immunity to Tuberculosis

article

Peripheral blood and pleural fluid mononuclear cell responses to low-molecular-mass secretory polypeptides of Mycobacterium tuberculosis in human models of immunity to tuberculosis

scientific article

Portrait of a pathogen: the Mycobacterium tuberculosis proteome in vivo

scientific article

Prospective on Mycobacterium tuberculosis proteomics

scientific article published on 19 October 2011

Proteomic analysis identifies highly antigenic proteins in exosomes from M. tuberculosis-infected and culture filtrate protein-treated macrophages

scientific article published on September 2010

Proteomic definition of the cell wall of Mycobacterium tuberculosis

scientific journal article

Purified protein derivatives of tuberculin--past, present, and future

scientific article

Quantitative analysis of phagolysosome fusion in intact cells: inhibition by mycobacterial lipoarabinomannan and rescue by an 1alpha,25-dihydroxyvitamin D3-phosphoinositide 3-kinase pathway

scientific article published in April 2004

RP105 Engages Phosphatidylinositol 3-Kinase p110δ To Facilitate the Trafficking and Secretion of Cytokines in Macrophages during Mycobacterial Infection

scientific article published on 14 September 2015

Risk factors for Buruli ulcer disease (Mycobacterium ulcerans infection): Results from a case-control study in Ghana

scientific article published on 12 April 2005

Serologic response to culture filtrate antigens of Mycobacterium ulcerans during Buruli ulcer disease

scientific article published on March 2000

Structural determinants in a glucose-containing lipopolysaccharide from Mycobacterium tuberculosis critical for inducing a subset of protective T cells.

scientific article published in May 2018

The human antibody response to the surface of Mycobacterium tuberculosis

scientific article

The non-clonality of drug resistance in Beijing-genotype isolates of Mycobacterium tuberculosis from the Western Cape of South Africa

scientific article

The presence of a galactosamine substituent on the arabinogalactan of Mycobacterium tuberculosis abrogates full maturation of human peripheral blood monocyte-derived dendritic cells and increases secretion of IL-10.

scientific article published on 14 May 2015

Three protein cocktails mediate delayed-type hypersensitivity responses indistinguishable from that elicited by purified protein derivative in the guinea pig model of Mycobacterium tuberculosis infection

scientific article

Upregulation of the phthiocerol dimycocerosate biosynthetic pathway by rifampin-resistant, rpoB mutant Mycobacterium tuberculosis

scientific article

Variation among genome sequences of H37Rv strains of Mycobacterium tuberculosis from multiple laboratories

scientific article

Virulence of Mycobacterium tuberculosis after Acquisition of Isoniazid Resistance: Individual Nature of katG Mutants and the Possible Role of AhpC

scientific article

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