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List of works by Yun Huang

A combination strategy targeting enhancer plasticity exerts synergistic lethality against BETi-resistant leukemia cells

scientific article published on 06 February 2020

A molecular toolbox for interrogation of membrane contact sites

scientific article published on 23 May 2019

A probabilistic generative model for quantification of DNA modifications enables analysis of demethylation pathways

scientific article published on 14 March 2016

A single EF-hand isolated from STIM1 forms dimer in the absence and presence of Ca2+

scientific article

Calcium-dependent association of calmodulin with the rubella virus nonstructural protease domain

scientific article

Calmodulin Regulates Ca2+-sensing Receptor-mediated Ca2+ Signaling and Its Cell Surface Expression

scientific article published on September 8, 2010

Calmodulin mediates the Ca2+-dependent regulation of Cx44 gap junctions.

scientific article published on April 2009

Connections between TET proteins and aberrant DNA modification in cancer

scientific article

Control of Foxp3 stability through modulation of TET activity

scientific article published on 22 February 2016

DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells

scientific article published on 18 July 2016

Design and application of a class of sensors to monitor Ca2+ dynamics in high Ca2+ concentration cellular compartments

scientific article

Dissecting the dynamic changes of 5-hydroxymethylcytosine in T-cell development and differentiation

scientific article

Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells

scientific article published on 13 January 2014

Elevated Adenosine Induces Placental DNA Hypomethylation Independent of A2B Receptor Signaling in Preeclampsia

scientific article

Elucidation of a novel extracellular calcium-binding site on metabotropic glutamate receptor 1{alpha} (mGluR1{alpha}) that controls receptor activation.

scientific article

Engineered Split-TET2 Enzyme for Inducible Epigenetic Remodeling.

scientific article published on 15 March 2017

Genetically encoded tags for real time dissection of protein assembly in living cells

scientific article published on 23 May 2018

Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells

scientific article

Global epigenomic reconfiguration during mammalian brain development

scientific article (publication date: 9 August 2013)

Identification of an L-phenylalanine binding site enhancing the cooperative responses of the calcium-sensing receptor to calcium.

scientific article published on 06 January 2014

Identification of the calmodulin binding domain of connexin 43

scientific article published on 27 September 2007

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

scientific article

KRAB domain of ZFP568 disrupts TRIM28-mediated abnormal interactions in cancer cells

scientific article published on 18 May 2020

Large conserved domains of low DNA methylation maintained by Dnmt3a

scientific article published on 24 November 2013

Molecular Determinants for STIM1 Activation During Store- Operated Ca2+ Entry

scientific article published on 19 February 2017

Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A.

scientific article

Mutations in 5-methylcytosine oxidase TET2 and RhoA cooperatively disrupt T cell homeostasis

scientific article published on 10 July 2017

N-methyl-N'-nitro-N-nitrosoguanidine interferes with the epidermal growth factor receptor-mediated signaling pathway

scientific article published in March 2005

Near-infrared photoactivatable control of Ca(2+) signaling and optogenetic immunomodulation

scientific article published on 8 December 2015

New functions for DNA modifications by TET-JBP.

scientific article published on November 2012

Optical control of membrane tethering and interorganellar communication at nanoscales.

scientific article published on 31 May 2017

Optogenetic engineering to probe the molecular choreography of STIM1-mediated cell signaling

scientific article published on 25 February 2020

Optogenetic toolkit for precise control of calcium signaling

scientific article published on 16 January 2017

P68 RNA helicase is a nucleocytoplasmic shuttling protein

scientific article published on 29 September 2009

Preferential CEBP binding to T:G mismatches and increased C-to-T human somatic mutations

scientific article published on 01 May 2021

Proteomic mapping of ER-PM junctions identifies STIMATE as a regulator of Ca²⁺ influx

scientific article

RNA modifications and cancer

scientific article published on 07 February 2020

Reliable tumor detection by whole-genome methylation sequencing of cell-free DNA in cerebrospinal fluid of pediatric medulloblastoma

scientific article published on 16 October 2020

Simultaneous sequencing of oxidized methylcytosines produced by TET/JBP dioxygenases in Coprinopsis cinerea

scientific article

Sphingolipids are involved in N-methyl-N'-nitro-N-nitrosoguanidine-induced epidermal growth factor receptor clustering

scientific article published in May 2005

Stage-specific roles for tet1 and tet2 in DNA demethylation in primordial germ cells

scientific article published on 14 February 2013

Structural basis for effects of CpA modifications on C/EBPβ binding of DNA

scientific article published on 01 February 2019

Structural basis for preferential binding of human TCF4 to DNA containing 5-carboxylcytosine

scientific article published on 01 September 2019

TET1-Mediated Oxidation of 5-Formylcytosine (5fC) to 5-Carboxycytosine (5caC) in RNA.

scientific article published on 2 November 2016

Tet inactivation disrupts YY1 binding and long-range chromatin interactions during embryonic heart development

scientific article published on 20 September 2019

Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells

scientific journal article

Tet2 Inactivation Enhances the Antitumor Activity of Tumor-Infiltrating Lymphocytes

scientific article published on 15 February 2021

The GLIB technique for genome-wide mapping of 5-hydroxymethylcytosine

scientific article

The anti-CMS technique for genome-wide mapping of 5-hydroxymethylcytosine

scientific article

The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing

scientific article (publication date: 26 January 2010)

The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine.

scientific article published on 27 April 2015

p53-dependent autophagic degradation of TET2 modulates cancer therapeutic resistance

scientific article published on 02 November 2018