List of works - Regina Rodrigo

Acute liver failure-induced death of rats is delayed or prevented by blocking NMDA receptors in brain.

scientific article published on 3 July 2008

Adalimumab Reduces Photoreceptor Cell Death in A Mouse Model of Retinal Degeneration.

scientific article published on 14 July 2015

Altered antioxidant-oxidant status in the aqueous humor and peripheral blood of patients with retinitis pigmentosa.

scientific article

Altered modulation of motor activity by group I metabotropic glutamate receptors in the nucleus accumbens in hyperammonemic rats

scientific article

Altered modulation of soluble guanylate cyclase by nitric oxide in patients with liver disease.

scientific article

Altered modulation of soluble guanylate cyclase in lymphocytes from patients with liver disease.

scientific article

Bile duct ligation plus hyperammonemia in rats reproduces the alterations in the modulation of soluble guanylate cyclase by nitric oxide in brain of cirrhotic patients

scientific article published in January 2005

Brain cholinergic impairment in liver failure.

scientific article published on 04 September 2008

Brain edema and inflammatory activation in bile duct ligated rats with diet-induced hyperammonemia: A model of hepatic encephalopathy in cirrhosis.

scientific article published in June 2006

Brain region-selective mechanisms contribute to the progression of cerebral alterations in acute liver failure in rats.

scientific article published on 25 October 2010

Brain regional alterations in the modulation of the glutamate-nitric oxide-cGMP pathway in liver cirrhosis. Role of hyperammonemia and cell types involved.

scientific article

Cerebral oedema is not responsible for motor or cognitive deficits in rats with hepatic encephalopathy.

scientific article

Chronic hyperammonemia induces tonic activation of NMDA receptors in cerebellum

scientific article published on 30 November 2009

Chronic hyperammonemia reduces the activity of neuronal nitric oxide synthase in cerebellum by altering its localization and increasing its phosphorylation by calcium-calmodulin kinase II.

scientific article published on 21 May 2008

Control of brain glutamine synthesis by NMDA receptors.

scientific article published on January 2007

Cyclic GMP pathways in hepatic encephalopathy. Neurological and therapeutic implications.

scientific article published on 02 March 2010

Glutamate-induced activation of nitric oxide synthase is impaired in cerebral cortex in vivo in rats with chronic liver failure

scientific article published on 5 February 2007

Glutamine synthetase activity and glutamine content in brain: modulation by NMDA receptors and nitric oxide ⬇️

scientific article published on September 1, 2003

HIF-1α stabilization reduces retinal degeneration in a mouse model of retinitis pigmentosa

scientific article published on 2 January 2018

Haemodynamic effects of long-term administration of sildenafil in normotensive pregnant and non-pregnant rats.

scientific article published on 18 January 2011

Hyperammonaemia alters the mechanisms by which metabotropic glutamate receptors in nucleus accumbens modulate motor function.

scientific article published on 22 June 2007

Hyperammonemia induces neuroinflammation that contributes to cognitive impairment in rats with hepatic encephalopathy

scientific article published on 18 March 2010

Inflammation and hepatic encephalopathy: ibuprofen restores learning ability in rats with portacaval shunts.

scientific article published in August 2007

Infliximab reduces Zaprinast-induced retinal degeneration in cultures of porcine retina

scientific article

Mechanisms of cognitive alterations in hyperammonemia and hepatic encephalopathy: therapeutical implications.

scientific article published on 6 February 2009

Mutational screening of the USH2A gene in Spanish USH patients reveals 23 novel pathogenic mutations

scientific article published on 17 October 2011

NMDA receptors in hyperammonemia and hepatic encephalopathy.

scientific article published on December 2007

Neuroinflammation contributes to hypokinesia in rats with hepatic encephalopathy: ibuprofen restores its motor activity

scientific article published in May 2009

Neurons exposed to ammonia reproduce the differential alteration in nitric oxide modulation of guanylate cyclase in the cerebellum and cortex of patients with liver cirrhosis

scientific article

Novel mutations in the USH1C gene in Usher syndrome patients.

scientific article

Oral administration of sildenafil restores learning ability in rats with hyperammonemia and with portacaval shunts

scientific article published in February 2005

Pharmacological manipulation of cyclic GMP levels in brain restores learning ability in animal models of hepatic encephalopathy: therapeutic implications.

scientific article published on March 2006

Phosphate-activated glutaminase activity is enhanced in brain, intestine and kidneys of rats following portacaval anastomosis

scientific article published on April 2006

Phosphodiesterase inhibition induces retinal degeneration, oxidative stress and inflammation in cone-enriched cultures of porcine retina

scientific article published on 9 April 2013

Polychlorinated biphenyls PCB 153 and PCB 126 impair the glutamate-nitric oxide-cGMP pathway in cerebellar neurons in culture by different mechanisms.

scientific article published on 29 April 2009

Proteome analysis of primary neurons and astrocytes from rat cerebellum

scientific article

Role of NMDA receptors in acute liver failure and ammonia toxicity: therapeutical implications.

scientific article published on 22 January 2009

Selective regional alterations in the content or distribution of neuronal and glial cytoskeletal proteins in brain of rats chronically exposed to 2,5-hexanedione

scientific article published in August 2002

Study of USH1 splicing variants through minigenes and transcript analysis from nasal epithelial cells

scientific article

Targeted next generation sequencing for molecular diagnosis of Usher syndrome.

scientific article

Two novel disease-causing mutations in the CLRN1 gene in patients with Usher syndrome type 3.

scientific article published on 29 December 2012

cGMP modulates stem cells differentiation to neurons in brain in vivo

scientific article published in December 2009

cGMP modulates stem cells differentiation to neurons in brain in vivo pathological implications.

scientific article published in August 2011

cGMP-Phosphodiesterase Inhibition Prevents Hypoxia-Induced Cell Death Activation in Porcine Retinal Explants

scientific article

p38 MAP kinase is a therapeutic target for hepatic encephalopathy in rats with portacaval shunts.

scientific article published on 2 June 2011

List of works by Regina Rodrigo

Acute liver failure-induced death of rats is delayed or prevented by blocking NMDA receptors in brain.

Adalimumab Reduces Photoreceptor Cell Death in A Mouse Model of Retinal Degeneration.

Altered antioxidant-oxidant status in the aqueous humor and peripheral blood of patients with retinitis pigmentosa.

Altered modulation of motor activity by group I metabotropic glutamate receptors in the nucleus accumbens in hyperammonemic rats

Altered modulation of soluble guanylate cyclase by nitric oxide in patients with liver disease.

Altered modulation of soluble guanylate cyclase in lymphocytes from patients with liver disease.

Bile duct ligation plus hyperammonemia in rats reproduces the alterations in the modulation of soluble guanylate cyclase by nitric oxide in brain of cirrhotic patients

Brain cholinergic impairment in liver failure.

Brain edema and inflammatory activation in bile duct ligated rats with diet-induced hyperammonemia: A model of hepatic encephalopathy in cirrhosis.

Brain region-selective mechanisms contribute to the progression of cerebral alterations in acute liver failure in rats.

Brain regional alterations in the modulation of the glutamate-nitric oxide-cGMP pathway in liver cirrhosis. Role of hyperammonemia and cell types involved.

Cerebral oedema is not responsible for motor or cognitive deficits in rats with hepatic encephalopathy.

Chronic hyperammonemia induces tonic activation of NMDA receptors in cerebellum

Chronic hyperammonemia reduces the activity of neuronal nitric oxide synthase in cerebellum by altering its localization and increasing its phosphorylation by calcium-calmodulin kinase II.

Control of brain glutamine synthesis by NMDA receptors.

Cyclic GMP pathways in hepatic encephalopathy. Neurological and therapeutic implications.

Glutamate-induced activation of nitric oxide synthase is impaired in cerebral cortex in vivo in rats with chronic liver failure

Glutamine synthetase activity and glutamine content in brain: modulation by NMDA receptors and nitric oxide ⬇️

HIF-1α stabilization reduces retinal degeneration in a mouse model of retinitis pigmentosa

Haemodynamic effects of long-term administration of sildenafil in normotensive pregnant and non-pregnant rats.

Hyperammonaemia alters the mechanisms by which metabotropic glutamate receptors in nucleus accumbens modulate motor function.

Hyperammonemia induces neuroinflammation that contributes to cognitive impairment in rats with hepatic encephalopathy

Inflammation and hepatic encephalopathy: ibuprofen restores learning ability in rats with portacaval shunts.

Infliximab reduces Zaprinast-induced retinal degeneration in cultures of porcine retina

Mechanisms of cognitive alterations in hyperammonemia and hepatic encephalopathy: therapeutical implications.

Mutational screening of the USH2A gene in Spanish USH patients reveals 23 novel pathogenic mutations

NMDA receptors in hyperammonemia and hepatic encephalopathy.

Neuroinflammation contributes to hypokinesia in rats with hepatic encephalopathy: ibuprofen restores its motor activity

Neurons exposed to ammonia reproduce the differential alteration in nitric oxide modulation of guanylate cyclase in the cerebellum and cortex of patients with liver cirrhosis

Novel mutations in the USH1C gene in Usher syndrome patients.

Oral administration of sildenafil restores learning ability in rats with hyperammonemia and with portacaval shunts

Pharmacological manipulation of cyclic GMP levels in brain restores learning ability in animal models of hepatic encephalopathy: therapeutic implications.

Phosphate-activated glutaminase activity is enhanced in brain, intestine and kidneys of rats following portacaval anastomosis

Phosphodiesterase inhibition induces retinal degeneration, oxidative stress and inflammation in cone-enriched cultures of porcine retina

Polychlorinated biphenyls PCB 153 and PCB 126 impair the glutamate-nitric oxide-cGMP pathway in cerebellar neurons in culture by different mechanisms.

Proteome analysis of primary neurons and astrocytes from rat cerebellum

Role of NMDA receptors in acute liver failure and ammonia toxicity: therapeutical implications.

Selective regional alterations in the content or distribution of neuronal and glial cytoskeletal proteins in brain of rats chronically exposed to 2,5-hexanedione

Study of USH1 splicing variants through minigenes and transcript analysis from nasal epithelial cells

Targeted next generation sequencing for molecular diagnosis of Usher syndrome.

Two novel disease-causing mutations in the CLRN1 gene in patients with Usher syndrome type 3.

cGMP modulates stem cells differentiation to neurons in brain in vivo

cGMP modulates stem cells differentiation to neurons in brain in vivo pathological implications.

cGMP-Phosphodiesterase Inhibition Prevents Hypoxia-Induced Cell Death Activation in Porcine Retinal Explants

p38 MAP kinase is a therapeutic target for hepatic encephalopathy in rats with portacaval shunts.