List of works - Sara I Börjesson

An electrostatic potassium channel opener targeting the final voltage sensor transition ⬇️

scientific article

An intracellular glucose biosensor based on nanoflake ZnO

Correction: Polyunsaturated fatty acid analogues differentially affect cardiac NaV, CaV, and KV channels through unique mechanisms

scientific article published on 18 June 2020

Dampening of hyperexcitability in CA1 pyramidal neurons by polyunsaturated fatty acids acting on voltage-gated ion channels

scientific article

Drug-induced ion channel opening tuned by the voltage sensor charge profile

scientific article published on 13 January 2014

Electronic polymers in lipid membranes

scientific article published on 10 June 2015

Electrostatic tuning of cellular excitability

scientific article

Fatty acid analogue N-arachidonoyl taurine restores function of IKs channels with diverse long QT mutations

scientific article published on 30 September 2016

Identification of PUFA interaction sites on the cardiac potassium channel KCNQ1

scientific article published on 03 May 2021

Intracellular K+ concentration decrease is not obligatory for apoptosis

scientific article

KCNE1 divides the voltage sensor movement in KCNQ1/KCNE1 channels into two steps

scientific article

KCNE1 tunes the sensitivity of K7.1 to polyunsaturated fatty acids by moving turret residues close to the binding site

scientific article published on 17 July 2018

Lipoelectric modification of ion channel voltage gating by polyunsaturated fatty acids

scientific article published on 23 May 2008

Mechanisms Underlying the Dual Effect of Polyunsaturated Fatty Acid Analogs on Kv7.1

scientific article published on 01 September 2018

Polyunsaturated fatty acid analogs act antiarrhythmically on the cardiac IKs channel

scientific article published on 21 April 2015

Polyunsaturated fatty acid analogues differentially affect cardiac Nav, Cav, and Kv channels through unique mechanisms

scientific article published on 24 March 2020

Polyunsaturated fatty acid-derived IKs channel activators shorten the QT interval ex-vivo and in-vivo

scientific article published on 29 March 2020

Polyunsaturated fatty acids and cerebrospinal fluid from children on the ketogenic diet open a voltage-gated K channel: a putative mechanism of antiseizure action

scientific article

Polyunsaturated fatty acids are potent openers of human M-channels expressed in Xenopus laevis oocytes

scientific article

Reciprocal voltage sensor-to-pore coupling leads to potassium channel C-type inactivation

scientific article published on 09 June 2016

Structure, function, and modification of the voltage sensor in voltage-gated ion channels

scientific article

The KCNQ1 channel - remarkable flexibility in gating allows for functional versatility

scientific article

The conserved phenylalanine in the K+ channel voltage-sensor domain creates a barrier with unidirectional effects

scientific article published on 8 January 2013

The free energy barrier for arginine gating charge translation is altered by mutations in the voltage sensor domain

scientific article

Tracking a complete voltage-sensor cycle with metal-ion bridges

scientific article

ω-6 and ω-9 polyunsaturated fatty acids with double bonds near the carboxyl head have the highest affinity and largest effects on the cardiac IK s potassium channel.

scientific article published on 17 October 2018

List of works by Sara I Börjesson

An electrostatic potassium channel opener targeting the final voltage sensor transition ⬇️

An intracellular glucose biosensor based on nanoflake ZnO

Correction: Polyunsaturated fatty acid analogues differentially affect cardiac NaV, CaV, and KV channels through unique mechanisms

Dampening of hyperexcitability in CA1 pyramidal neurons by polyunsaturated fatty acids acting on voltage-gated ion channels

Drug-induced ion channel opening tuned by the voltage sensor charge profile

Electronic polymers in lipid membranes

Electrostatic tuning of cellular excitability

Fatty acid analogue N-arachidonoyl taurine restores function of IKs channels with diverse long QT mutations

Identification of PUFA interaction sites on the cardiac potassium channel KCNQ1

Intracellular K+ concentration decrease is not obligatory for apoptosis

KCNE1 divides the voltage sensor movement in KCNQ1/KCNE1 channels into two steps

KCNE1 tunes the sensitivity of K7.1 to polyunsaturated fatty acids by moving turret residues close to the binding site

Lipoelectric modification of ion channel voltage gating by polyunsaturated fatty acids

Mechanisms Underlying the Dual Effect of Polyunsaturated Fatty Acid Analogs on Kv7.1

Polyunsaturated fatty acid analogs act antiarrhythmically on the cardiac IKs channel

Polyunsaturated fatty acid analogues differentially affect cardiac Nav, Cav, and Kv channels through unique mechanisms

Polyunsaturated fatty acid-derived IKs channel activators shorten the QT interval ex-vivo and in-vivo

Polyunsaturated fatty acids and cerebrospinal fluid from children on the ketogenic diet open a voltage-gated K channel: a putative mechanism of antiseizure action

Polyunsaturated fatty acids are potent openers of human M-channels expressed in Xenopus laevis oocytes

Reciprocal voltage sensor-to-pore coupling leads to potassium channel C-type inactivation

Structure, function, and modification of the voltage sensor in voltage-gated ion channels

The KCNQ1 channel - remarkable flexibility in gating allows for functional versatility

The conserved phenylalanine in the K+ channel voltage-sensor domain creates a barrier with unidirectional effects

The free energy barrier for arginine gating charge translation is altered by mutations in the voltage sensor domain

Tracking a complete voltage-sensor cycle with metal-ion bridges

ω-6 and ω-9 polyunsaturated fatty acids with double bonds near the carboxyl head have the highest affinity and largest effects on the cardiac IK s potassium channel.