List of works - Per Hammarstrom

A highly insoluble state of Abeta similar to that of Alzheimer's disease brain is found in Arctic APP transgenic mice

scientific article published on 14 January 2008

A nonessential role for Arg 55 in cyclophilin18 for catalysis of proline isomerization during protein folding

scientific article published in February 2009

A pentameric luminescent-conjugated oligothiophene for optical imaging of in vitro-formed amyloid fibrils and protein aggregates in tissue sections

scientific article published in January 2012

Activity, folding, misfolding, and aggregation in vitro of the naturally occurring human tissue factor mutant R200W.

scientific article published in May 2005

Aggregated Aβ1-42 Is Selectively Toxic for Neurons, Whereas Glial Cells Produce Mature Fibrils with Low Toxicity in Drosophila.

scientific article published on 2 April 2018

Amyloid fibril polymorphism - a challenge for molecular imaging and therapy

scientific article

Amyloid fibrils of human prion protein are spun and woven from morphologically disordered aggregates

scientific article published on 16 October 2009

Amyloid oligomers: spectroscopic characterization of amyloidogenic protein states.

scientific article published on 09 February 2010

An engineered transthyretin monomer that is nonamyloidogenic, unless it is partially denatured

scientific article

Anion shielding of electrostatic repulsions in transthyretin modulates stability and amyloidosis: insight into the chaotrope unfolding dichotomy

scientific article

Binding of Polythiophenes to Amyloids: Structural Mapping of the Pharmacophore.

scientific article published on 27 November 2017

Cell interaction study of amyloid by using luminescent conjugated polythiophene: implication that amyloid cytotoxicity is correlated with prolonged cellular binding

scientific article published on 19 January 2012

Cofactor-induced refolding: refolding of molten globule carbonic anhydrase induced by Zn(II) and Co(II).

scientific article published in March 2001

Conformational rearrangements of tail-less complex polypeptide 1 (TCP-1) ring complex (TRiC)-bound actin

scientific article published on 07 April 2007

Conjugated polyelectrolytes--conformation-sensitive optical probes for staining and characterization of amyloid deposits

scientific article published in July 2006

Conjugated polyelectrolytes: conformation-sensitive optical probes for detection of amyloid fibril formation.

scientific article

Curcumin promotes A-beta fibrillation and reduces neurotoxicity in transgenic Drosophila

scientific article published in 2012

Detection and Imaging of Aβ1-42 and Tau Fibrils by Redesigned Fluorescent X-34 Analogues.

scientific article published on 15 March 2018

Domain-specific chaperone-induced expansion is required for beta-actin folding: a comparison of beta-actin conformations upon interactions with GroEL and tail-less complex polypeptide 1 ring complex (TRiC)

scientific article published on 16 October 2007

EPR mapping of interactions between spin-labeled variants of human carbonic anhydrase II and GroEL: evidence for increased flexibility of the hydrophobic core by the interaction

scientific article published on 01 January 1999

Efficient imaging of amyloid deposits in Drosophila models of human amyloidoses

scientific article published on 29 April 2010

Enhanced fluorescent assignment of protein aggregates by an oligothiophene-porphyrin-based amyloid ligand

scientific article published on 7 March 2013

Evidence for age-dependent in vivo conformational rearrangement within Aβ amyloid deposits

scientific article

GroEL-induced topological dislocation of a substrate protein β-sheet core: a solution EPR spin–spin distance study ⬇️

scientific article published on April 11, 2010

Is the prevalent human prion protein 129M/V mutation a living fossil from a Paleolithic panzootic superprion pandemic?

scientific article

Multimodal Chemical Imaging of Amyloid Plaque Polymorphism Reveals Aβ Aggregation Dependent Anionic Lipid Accumulations and Metabolism

scientific article published on 19 June 2018

Multimodal fluorescence microscopy of prion strain specific PrP deposits stained by thiophene-based amyloid ligands

scientific article published on November 2014

Nanoscopic and photonic ultrastructural characterization of two distinct insulin amyloid states.

scientific article published on February 2012

Native, amyloid fibrils and β-oligomers of the C-terminal domain of human prion protein display differential activation of complement and bind C1q, factor H and C4b-binding protein directly

scientific article published on 11 April 2008

Observations in APP Bitransgenic Mice Suggest that Diffuse and Compact Plaques Form via Independent Processes in Alzheimer's Disease ⬇️

scientific article published on May 1, 2011

Phenolic Bis-styrylbenzo[ c]-1,2,5-thiadiazoles as Probes for Fluorescence Microscopy Mapping of Aβ Plaque Heterogeneity

scientific article published on 13 February 2019

Power tools for Alzheimer's disease - an electrochemical preamp for Aβ.

scientific article published in July 2012

Prevention of transthyretin amyloid disease by changing protein misfolding energetics.

scientific article

Protein folding, misfolding and disease

scientific article published on 16 July 2009

Pyrene excimer fluorescence as a proximity probe for investigation of residual structure in the unfolded state of human carbonic anhydrase II

scientific article published on 01 December 1997

Pyroglutamation of amyloid-βx-42 (Aβx-42) followed by Aβ1-40 deposition underlies plaque polymorphism in progressing Alzheimer's disease pathology

scientific article published in 2019

Reshaping the folding energy landscape by chloride salt: impact on molten-globule formation and aggregation behavior of carbonic anhydrase

scientific article

Retention of misfolded mutant transthyretin by the chaperone BiP/GRP78 mitigates amyloidogenesis

scientific article published on 5 December 2005

Seeded strain-like transmission of β-amyloid morphotypes in APP transgenic mice

scientific article published on 3 September 2013

Sensitive and rapid assessment of amyloid by oligothiophene fluorescence in subcutaneous fat tissue.

scientific article

Spatially controlled amyloid reactions using organic electronics.

scientific article published on October 2010

Spectral discrimination of cerebral amyloid lesions after peripheral application of luminescent conjugated oligothiophenes

scientific article published on 4 October 2012

Spectroscopic characterization of diverse amyloid fibrils in vitro by the fluorescent dye Nile red.

scientific article published on 31 January 2011

Synthesis of a library of oligothiophenes and their utilization as fluorescent ligands for spectral assignment of protein aggregates.

scientific article

Synthesis of a regioregular zwitterionic conjugated oligoelectrolyte, usable as an optical probe for detection of amyloid fibril formation at acidic pH.

scientific article

The bloody path of amyloids and prions

scientific article published on 01 June 2007

The cyclooxygenase-2 inhibitor celecoxib is a potent inhibitor of human carbonic anhydrase II.

scientific article published in October 2004

Thermodynamic interrogation of a folding disease. Mutant mapping of position 107 in human carbonic anhydrase II linked to marble brain disease

scientific article

Thermodynamic stability and denaturation kinetics of a benign natural transthyretin mutant identified in a Danish kindred.

scientific article published on 16 March 2011

Trans-suppression of misfolding in an amyloid disease.

scientific article

Transient conformational remodeling of folding proteins by GroES-individually and in concert with GroEL

scientific article published on 5 October 2013

Transthyretin slowly exchanges subunits under physiological conditions: A convenient chromatographic method to study subunit exchange in oligomeric proteins.

scientific article published on August 2001

Unfolding a folding disease: folding, misfolding and aggregation of the marble brain syndrome-associated mutant H107Y of human carbonic anhydrase II.

scientific article

List of works by Per Hammarstrom

A highly insoluble state of Abeta similar to that of Alzheimer's disease brain is found in Arctic APP transgenic mice

A nonessential role for Arg 55 in cyclophilin18 for catalysis of proline isomerization during protein folding

A pentameric luminescent-conjugated oligothiophene for optical imaging of in vitro-formed amyloid fibrils and protein aggregates in tissue sections

Activity, folding, misfolding, and aggregation in vitro of the naturally occurring human tissue factor mutant R200W.

Aggregated Aβ1-42 Is Selectively Toxic for Neurons, Whereas Glial Cells Produce Mature Fibrils with Low Toxicity in Drosophila.

Amyloid fibril polymorphism - a challenge for molecular imaging and therapy

Amyloid fibrils of human prion protein are spun and woven from morphologically disordered aggregates

Amyloid oligomers: spectroscopic characterization of amyloidogenic protein states.

An engineered transthyretin monomer that is nonamyloidogenic, unless it is partially denatured

Anion shielding of electrostatic repulsions in transthyretin modulates stability and amyloidosis: insight into the chaotrope unfolding dichotomy

Binding of Polythiophenes to Amyloids: Structural Mapping of the Pharmacophore.

Cell interaction study of amyloid by using luminescent conjugated polythiophene: implication that amyloid cytotoxicity is correlated with prolonged cellular binding

Cofactor-induced refolding: refolding of molten globule carbonic anhydrase induced by Zn(II) and Co(II).

Conformational rearrangements of tail-less complex polypeptide 1 (TCP-1) ring complex (TRiC)-bound actin

Conjugated polyelectrolytes--conformation-sensitive optical probes for staining and characterization of amyloid deposits

Conjugated polyelectrolytes: conformation-sensitive optical probes for detection of amyloid fibril formation.

Curcumin promotes A-beta fibrillation and reduces neurotoxicity in transgenic Drosophila

Detection and Imaging of Aβ1-42 and Tau Fibrils by Redesigned Fluorescent X-34 Analogues.

Domain-specific chaperone-induced expansion is required for beta-actin folding: a comparison of beta-actin conformations upon interactions with GroEL and tail-less complex polypeptide 1 ring complex (TRiC)

EPR mapping of interactions between spin-labeled variants of human carbonic anhydrase II and GroEL: evidence for increased flexibility of the hydrophobic core by the interaction

Efficient imaging of amyloid deposits in Drosophila models of human amyloidoses

Enhanced fluorescent assignment of protein aggregates by an oligothiophene-porphyrin-based amyloid ligand

Evidence for age-dependent in vivo conformational rearrangement within Aβ amyloid deposits

GroEL-induced topological dislocation of a substrate protein β-sheet core: a solution EPR spin–spin distance study ⬇️

Is the prevalent human prion protein 129M/V mutation a living fossil from a Paleolithic panzootic superprion pandemic?

Multimodal Chemical Imaging of Amyloid Plaque Polymorphism Reveals Aβ Aggregation Dependent Anionic Lipid Accumulations and Metabolism

Multimodal fluorescence microscopy of prion strain specific PrP deposits stained by thiophene-based amyloid ligands

Nanoscopic and photonic ultrastructural characterization of two distinct insulin amyloid states.

Native, amyloid fibrils and β-oligomers of the C-terminal domain of human prion protein display differential activation of complement and bind C1q, factor H and C4b-binding protein directly

Observations in APP Bitransgenic Mice Suggest that Diffuse and Compact Plaques Form via Independent Processes in Alzheimer's Disease ⬇️

Phenolic Bis-styrylbenzo[ c]-1,2,5-thiadiazoles as Probes for Fluorescence Microscopy Mapping of Aβ Plaque Heterogeneity

Power tools for Alzheimer's disease - an electrochemical preamp for Aβ.

Prevention of transthyretin amyloid disease by changing protein misfolding energetics.

Protein folding, misfolding and disease

Pyrene excimer fluorescence as a proximity probe for investigation of residual structure in the unfolded state of human carbonic anhydrase II

Pyroglutamation of amyloid-βx-42 (Aβx-42) followed by Aβ1-40 deposition underlies plaque polymorphism in progressing Alzheimer's disease pathology

Reshaping the folding energy landscape by chloride salt: impact on molten-globule formation and aggregation behavior of carbonic anhydrase

Retention of misfolded mutant transthyretin by the chaperone BiP/GRP78 mitigates amyloidogenesis

Seeded strain-like transmission of β-amyloid morphotypes in APP transgenic mice

Sensitive and rapid assessment of amyloid by oligothiophene fluorescence in subcutaneous fat tissue.

Spatially controlled amyloid reactions using organic electronics.

Spectral discrimination of cerebral amyloid lesions after peripheral application of luminescent conjugated oligothiophenes

Spectroscopic characterization of diverse amyloid fibrils in vitro by the fluorescent dye Nile red.

Synthesis of a library of oligothiophenes and their utilization as fluorescent ligands for spectral assignment of protein aggregates.

Synthesis of a regioregular zwitterionic conjugated oligoelectrolyte, usable as an optical probe for detection of amyloid fibril formation at acidic pH.

The bloody path of amyloids and prions

The cyclooxygenase-2 inhibitor celecoxib is a potent inhibitor of human carbonic anhydrase II.

Thermodynamic interrogation of a folding disease. Mutant mapping of position 107 in human carbonic anhydrase II linked to marble brain disease

Thermodynamic stability and denaturation kinetics of a benign natural transthyretin mutant identified in a Danish kindred.

Trans-suppression of misfolding in an amyloid disease.

Transient conformational remodeling of folding proteins by GroES-individually and in concert with GroEL

Transthyretin slowly exchanges subunits under physiological conditions: A convenient chromatographic method to study subunit exchange in oligomeric proteins.

Unfolding a folding disease: folding, misfolding and aggregation of the marble brain syndrome-associated mutant H107Y of human carbonic anhydrase II.