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List of works by Bruce Hope

Acute administration of cocaine regulates the phosphorylation of serine-19, -31 and -40 in tyrosine hydroxylase

scientific article

Amylin receptor components and the leptin receptor are co-expressed in single rat area postrema neurons

scientific article published on 10 January 2016

Anti-relapse neurons in the infralimbic cortex of rats drive relapse-suppression by drug omission cues

scientific article published on 02 September 2019

Association of time-dependent changes in mu opioid receptor mRNA, but not BDNF, TrkB, or MeCP2 mRNA and protein expression in the rat nucleus accumbens with incubation of heroin craving

scientific article

Associative Learning Drives the Formation of Silent Synapses in Neuronal Ensembles of the Nucleus Accumbens.

scientific article published on 14 August 2015

Behavioral and Physiological Effects of a Novel Kappa-Opioid Receptor-Based DREADD in Rats

scientific article published on 28 May 2015

Bidirectional Modulation of Intrinsic Excitability in Rat Prelimbic Cortex Neuronal Ensembles and Non-Ensembles after Operant Learning.

scientific article published on 4 August 2017

Blockade of adenosine A2A receptors prevents protein phosphorylation in the striatum induced by cortical stimulation.

scientific article published in October 2006

Brain neuronal CB2 cannabinoid receptors in drug abuse and depression: from mice to human subjects

scientific article

Bromocriptine administration reduces hyperphagia and adiposity and differentially affects dopamine D2 receptor and transporter binding in leptin-receptor-deficient Zucker rats and rats with diet-induced obesity

scientific article

Central amygdala ERK signaling pathway is critical to incubation of cocaine craving

scientific article published on 16 January 2005

Chasing the addicted engram: identifying functional alterations in Fos-expressing neuronal ensembles that mediate drug-related learned behavior

scientific article published on 16 August 2018

Chronic Fos-related antigens: stable variants of deltaFosB induced in brain by chronic treatments

scientific article

Chronic alterations in dopaminergic neurotransmission produce a persistent elevation of deltaFosB-like protein(s) in both the rodent and primate striatum

scientific article published on February 1996

Chronic electroconvulsive seizure (ECS) treatment results in expression of a long-lasting AP-1 complex in brain with altered composition and characteristics

scientific article published on July 1994

Chronic nicotine activates stress/reward-related brain regions and facilitates the transition to compulsive alcohol drinking

scientific article

Citrulline in the rat brain: immunohistochemistry and coexistence with NADPH-diaphorase

scientific article

Cocaine and synaptic alterations in the nucleus accumbens

scientific article

Cocaine and the AP-1 transcription factor complex

scientific article

Cocaine-induced CREB phosphorylation in nucleus accumbens of cocaine-sensitized rats is enabled by enhanced activation of extracellular signal-related kinase, but not protein kinase A.

scientific article

Cocaine-induced Fos expression in rat striatum is blocked by chloral hydrate or urethane.

scientific article

Cocaine-induced locomotor activity and Fos expression in nucleus accumbens are sensitized for 6 months after repeated cocaine administration outside the home cage.

scientific article published in August 2006

Context-induced reinstatement of methamphetamine seeking is associated with unique molecular alterations in Fos-expressing dorsolateral striatum neurons.

scientific article

Context-specific modulation of cocaine-induced locomotor sensitization and ERK and CREB phosphorylation in the rat nucleus accumbens.

scientific article published on 11 November 2009

Context-specific sensitization of cocaine-induced locomotor activity and associated neuronal ensembles in rat nucleus accumbens

scientific article

Daun02 Inactivation of Behaviorally Activated Fos-Expressing Neuronal Ensembles

scientific article

Detection of molecular alterations in methamphetamine-activated Fos-expressing neurons from a single rat dorsal striatum using fluorescence-activated cell sorting (FACS).

scientific article published on 21 August 2013

Differential long-term neuroadaptations of glutamate receptors in the basolateral and central amygdala after withdrawal from cocaine self-administration in rats

scientific article published in July 2005

Discovery of the presence and functional expression of cannabinoid CB2 receptors in brain

scientific article published on August 2006

Discriminative stimuli are sufficient for incubation of cocaine craving

scientific article published on 25 February 2019

Distinct Fos-Expressing Neuronal Ensembles in the Ventromedial Prefrontal Cortex Mediate Food Reward and Extinction Memories

scientific article published on June 2016

Distinct memory engrams in the infralimbic cortex of rats control opposing environmental actions on a learned behavior

scientific article published on 10 December 2016

Dopamine uptake through the norepinephrine transporter in brain regions with low levels of the dopamine transporter: evidence from knock-out mouse lines

scientific article (publication date: 15 January 2002)

Drug addiction: a model for the molecular basis of neural plasticity.

scientific article

Effect of cocaine and sucrose withdrawal period on extinction behavior, cue-induced reinstatement, and protein levels of the dopamine transporter and tyrosine hydroxylase in limbic and cortical areas in rats

scientific article

Enabling role of adenosine A1 receptors in adenosine A2A receptor-mediated striatal expression of c-fos

scientific article published in July 2003

Exploring the epigenetics of cocaine resistance

scientific article published in February 2013

FACS identifies unique cocaine-induced gene regulation in selectively activated adult striatal neurons

scientific article

FACS purification of immunolabeled cell types from adult rat brain.

scientific article published on 3 September 2011

Fluorescence Activated Cell Sorting (FACS) and Gene Expression Analysis of Fos-expressing Neurons from Fresh and Frozen Rat Brain Tissue

scientific article

Fos-expressing neuronal ensemble in rat ventromedial prefrontal cortex encodes cocaine seeking but not food seeking in rats

scientific article published on 19 July 2020

Functional expression of brain neuronal CB2 cannabinoid receptors are involved in the effects of drugs of abuse and in depression

scientific journal article

G(olf) in the basal ganglia.

scientific article published on February 1991

Heteromeric nicotinic acetylcholine-dopamine autoreceptor complexes modulate striatal dopamine release.

scientific article published on 17 May 2006

Histochemical characterization of neuronal NADPH-diaphorase

scientific article published in May 1989

Identification of tyrosine hydroxylase as a physiological substrate for Cdk5.

scientific article published on October 2004

Improved methods for marking active neuron populations

scientific article published in Nature Communications

Incubation of cocaine craving after withdrawal: a review of preclinical data

scientific article

Incubation of methamphetamine craving is associated with selective increases in expression of Bdnf and trkb, glutamate receptors, and epigenetic enzymes in cue-activated fos-expressing dorsal striatal neurons

scientific article published on May 2015

Induction of a long-lasting AP-1 complex composed of altered Fos-like proteins in brain by chronic cocaine and other chronic treatments.

scientific article published in November 1994

Induction of the c-fos proto-oncogene in rat amygdala during unconditioned and conditioned fear

scientific article

Involvement of cAMP-dependent protein kinase in the nucleus accumbens in cocaine self-administration and relapse of cocaine-seeking behavior.

scientific article

Kappa-opioid receptor activation prevents alterations in mesocortical dopamine neurotransmission that occur during abstinence from cocaine

scientific article

Locomotor sensitization to cocaine is associated with increased Fos expression in the accumbens, but not in the caudate

scientific article published in November 2002

Long-term upregulation of protein kinase A and adenylate cyclase levels in human smokers.

scientific article published on February 2007

Losing Control: Excessive Alcohol Seeking after Selective Inactivation of Cue-Responsive Neurons in the Infralimbic Cortex.

scientific article published on July 2015

Medial prefrontal cortex neuronal activation and synaptic alterations after stress-induced reinstatement of palatable food seeking: a study using c-fos-GFP transgenic female rats

scientific article

Mitogen-activated protein kinase regulates dopamine transporter surface expression and dopamine transport capacity.

scientific article

Molecular neuroadaptations in the accumbens and ventral tegmental area during the first 90 days of forced abstinence from cocaine self-administration in rats

scientific article

Neuroadaptation. Incubation of cocaine craving after withdrawal

scientific article

Neuroadaptations of total levels of adenylate cyclase, protein kinase A, tyrosine hydroxylase, cdk5 and neurofilaments in the nucleus accumbens and ventral tegmental area do not correlate with expression of sensitized or tolerant locomotor responses

scientific article published in February 2005

Neurobiology of the incubation of drug craving

scientific article

Neurons that say NO

scientific article published on March 1, 1992

New technologies for examining the role of neuronal ensembles in drug addiction and fear

scientific article

Optogenetic inhibition of dorsal medial prefrontal cortex attenuates stress-induced reinstatement of palatable food seeking in female rats

scientific article published on January 2013

Parametric investigation of social place preference in adolescent mice

scientific article published on 16 July 2020

Pharmacological studies of the regulation of chronic FOS-related antigen induction by cocaine in the striatum and nucleus accumbens.

scientific article published in December 1995

Prelimbic cortex is a common brain area activated during cue-induced reinstatement of cocaine and heroin seeking in a polydrug self-administration rat model

article

Recruitment of a Neuronal Ensemble in the Central Nucleus of the Amygdala Is Required for Alcohol Dependence.

scientific article published on September 2016

Regulation of delta FosB and FosB-like proteins by electroconvulsive seizure and cocaine treatments.

scientific article published in November 1995

Regulation of immediate early gene expression and AP-1 binding in the rat nucleus accumbens by chronic cocaine

scientific article

Regulation of neural gene expression in opiate and cocaine addiction.

scientific article

Relapse-associated Transient Synaptic Potentiation Requires Integrin-mediated Activation of Focal Adhesion Kinase and Cofilin in D1-expressing Neurons

scientific article published on 13 October 2020

Repeated amphetamine administration outside the home cage enhances drug-induced Fos expression in rat nucleus accumbens

scientific article

Repeated quinpirole treatment increases cAMP-dependent protein kinase activity and CREB phosphorylation in nucleus accumbens and reverses quinpirole-induced sensorimotor gating deficits in rats

scientific article

Role of Central Amygdala Neuronal Ensembles in Incubation of Nicotine Craving

scientific article published on August 2016

Role of Dorsomedial Striatum Neuronal Ensembles in Incubation of Methamphetamine Craving after Voluntary Abstinence.

scientific article published on January 2017

Role of ERK in cocaine addiction.

scientific article published on 7 November 2006

Role of Ventral Subiculum in Context-Induced Relapse to Alcohol Seeking after Punishment-Imposed Abstinence

scientific article published on March 2016

Role of adenosine in the control of homosynaptic plasticity in striatal excitatory synapses.

scientific article

Role of nucleus accumbens shell neuronal ensembles in context-induced reinstatement of cocaine-seeking

scientific article

Role of orbitofrontal cortex neuronal ensembles in the expression of incubation of heroin craving

scientific article

Role of ventral medial prefrontal cortex in incubation of cocaine craving.

scientific article published on 08 May 2008

Separate vmPFC Ensembles Control Cocaine Self-Administration Versus Extinction in Rats

scientific article published on 22 July 2019

Silent synapses in selectively activated nucleus accumbens neurons following cocaine sensitization

scientific article

Stimulation of adenosine receptors selectively activates gene expression in striatal enkephalinergic neurons

scientific article published in February 2006

Striatal adenosine A2A and cannabinoid CB1 receptors form functional heteromeric complexes that mediate the motor effects of cannabinoids

scientific journal article

Synergistic interaction between adenosine A2A and glutamate mGlu5 receptors: implications for striatal neuronal function.

scientific article

Targeted disruption of cocaine-activated nucleus accumbens neurons prevents context-specific sensitization

scientific article

The cystine-glutamate transporter in the accumbens: a novel role in cocaine relapse

scientific article published on February 2004

The role of neuroadaptations in relapse to drug seeking

scientific article

Time-dependent changes in extinction behavior and stress-induced reinstatement of drug seeking following withdrawal from heroin in rats

scientific article published in June 2001

Tolerance to opiate reward: role of midbrain IRS2-Akt pathway.

scientific article published in January 2007

Unique gene alterations are induced in FACS-purified Fos-positive neurons activated during cue-induced relapse to heroin seeking

scientific article

Using c-fos to study neuronal ensembles in corticostriatal circuitry of addiction

scientific article published on 11 November 2014

Ventral medial prefrontal cortex neuronal ensembles mediate context-induced relapse to heroin

scientific article

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