Search filters

List of works by Alessandra Moretti

A new hERG allosteric modulator rescues genetic and drug-induced long-QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells

scientific article published on 28 July 2016

Automated analysis of contractile force and Ca2+ transients in engineered heart tissue.

scientific article

Blocking caspase-activated apoptosis improves contractility in failing myocardium

scientific article published in November 2001

Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia

scientific article

Diabetes Mellitus-Induced Microvascular Destabilization in the Myocardium

scientific article published on January 2017

Direct Nkx2-5 Transcriptional Repression of Isl1 Controls Cardiomyocyte Subtype Identity

scientific article published on 01 April 2015

Elucidating arrhythmogenic mechanisms of long-QT syndrome CALM1-F142L mutation in patient-specific induced pluripotent stem cell-derived cardiomyocytes.

scientific article published on 2 February 2017

Essential myosin light chain as a target for caspase-3 in failing myocardium

scientific article

Extending human induced pluripotent stem cell technology to infectious diseases: new model for viral myocarditis

scientific article published in August 2014

Functional comparison of induced pluripotent stem cell- and blood-derived GPIIbIIIa deficient platelets

scientific article

Gene transfer of heterologous G protein-coupled receptors to cardiomyocytes: differential effects on contractility.

scientific article

Gene transfer of the pancaspase inhibitor P35 reduces myocardial infarct size and improves cardiac function

scientific article published on 21 June 2005

Human Engineered Heart Tissue: Analysis of Contractile Force

scientific article published on 18 May 2016

Induced pluripotent stem cell-derived cardiomyocytes for drug development and toxicity testing.

scientific article published on 19 March 2014

Induced pluripotent stem cells in cardiovascular research

scientific article published on January 2012

Interplay of cell-cell contacts and RhoA/MRTF-A signaling regulates cardiomyocyte identity.

scientific article

Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long-QT syndrome

scientific article

Live fluorescent RNA-based detection of pluripotency gene expression in embryonic and induced pluripotent stem cells of different species

scientific article published in February 2015

MicroRNAs in a Cardiac Loop: Progenitor or Myocyte? ⬇️

scientific article published on December 14, 2010

Migratory and anti-fibrotic programmes define the regenerative potential of human cardiac progenitors

scientific article published on 12 May 2022

Modeling long-QT syndromes with iPS cells.

scientific article published on 18 October 2012

Modulation of hERG potassium channel gating normalizes action potential duration prolonged by dysfunctional KCNQ1 potassium channel

scientific article

Mouse and human induced pluripotent stem cells as a source for multipotent Isl1+ cardiovascular progenitors

scientific article published on 22 October 2009

Multipotent Progenitor Cells in Regenerative Cardiovascular Medicine

scientific article published on 05 May 2009

Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification

scientific article

Negating the dominant-negative allele: a new treatment paradigm for arrhythmias explored in human induced pluripotent stem cell-derived cardiomyocytes

scientific article published on 12 April 2013

Neuropotent self-renewing neural stem (NS) cells derived from mouse induced pluripotent stem (iPS) cells

article

Patient-specific induced pluripotent stem-cell models for long-QT syndrome

scientific article (publication date: 7 October 2010)

Perspectives and Challenges of Pluripotent Stem Cells in Cardiac Arrhythmia Research.

scientific article published on March 2017

Pluripotent stem cell models of human heart disease

scientific article

Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages

scientific article

Progressive stretch enhances growth and maturation of 3D stem-cell-derived myocardium

scientific article published on 15 April 2021

Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy

scientific article published on 27 January 2020

Subtype-specific promoter-driven action potential imaging for precise disease modelling and drug testing in hiPSC-derived cardiomyocytes

scientific article published in January 2017

Paulina is supported by:

About Paulina

Help