Search filters

List of works by Geert Berx

A constitutional translocation t(1;17)(p36.2;q11.2) in a neuroblastoma patient disrupts the human NBPF1 and ACCN1 genes

scientific article

A new mouse model to study the role of ectopic Nanos3 expression in cancer.

scientific article published on 17 June 2019

A novel RIPK4-IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes

scientific article published on 28 November 2014

A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment

scientific article published on 06 May 2019

Allelic imbalance at the beta-catenin gene (CTNNB1 at 3p22-21.3) in various human tumor types.

scientific article

Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes

scientific article published on 02 September 2009

An Ovol2-Zeb1 transcriptional circuit regulates epithelial directional migration and proliferation

scientific article published on 09 November 2018

An efficient and reliable multiplex PCR-SSCP mutation analysis test applied to the human E-cadherin gene

scientific article

Assignment of the human beta-catenin gene (CTNNB1) to 3p22-->p21.3 by fluorescence in situ hybridization

scientific article

Cadherins and epithelial-to-mesenchymal transition

scientific article published on January 2013

Cadherins in cancer

scientific article published in January 2004

Cloning and characterization of the human invasion suppressor gene E-cadherin (CDH1).

scientific article

Combined subtractive cDNA cloning and array CGH: an efficient approach for identification of overexpressed genes in DNA amplicons

scientific article

Concepts of metastasis in flux: the stromal progression model

scientific article published on 21 February 2012

Confounding factors of ultrafiltration and protein analysis in extracellular vesicle research

scientific article

DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells

scientific article

Deregulation of the replisome factor MCMBP prompts oncogenesis in colorectal carcinomas through chromosomal instability

scientific article

Development and characterization of a new human hepatic cell line.

scientific article

Direct repression of cyclin D1 by SIP1 attenuates cell cycle progression in cells undergoing an epithelial mesenchymal transition.

scientific article published on 12 September 2007

Directed migration of cortical interneurons depends on the cell-autonomous action of Sip1.

scientific article

Distinct deleted regions on chromosome segment 16q23-24 associated with metastases in prostate cancer

scientific article published in March 1999

Dysregulation of the E-cadherin/catenin complex by irreversible mutations in human carcinomas.

scientific article published in January 1998

E-cadherin gene (CDH1) promoter methylation as the second hit in sporadic diffuse gastric carcinoma

article

E-cadherin gene alterations are rare events in thyroid tumors

article

E-cadherin gene mutations provide a genetic basis for the phenotypic divergence of mixed gastric carcinomas

scientific article published on 01 April 1999

E-cadherin inactivation in lobular carcinoma in situ of the breast: an early event in tumorigenesis ⬇️

scientific article published on January 1, 1997

E-cadherin is inactivated in a majority of invasive human lobular breast cancers by truncation mutations throughout its extracellular domain.

scientific article

EMT transcription factors in cancer development re-evaluated: Beyond EMT and MET.

scientific article published on 29 June 2017

EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research.

scientific article published on February 2017

Efficient mouse transgenesis using Gateway-compatible ROSA26 locus targeting vectors and F1 hybrid ES cells

scientific article published on 11 March 2009

Elevated ΔNp63α Levels Facilitate Epidermal and Biliary Oncogenic Transformation

scientific article published on 7 October 2016

Epidermal Snail expression drives skin cancer initiation and progression through enhanced cytoprotection, epidermal stem/progenitor cell expansion and enhanced metastatic potential

scientific article published on 25 October 2013

Epithelial-to-Mesenchymal Transition: Epigenetic Reprogramming Driving Cellular Plasticity.

scientific article published on 14 September 2017

Evolutionary functional analysis and molecular regulation of the ZEB transcription factors

scientific article published on 21 February 2012

Expressed repetitive elements are broadly applicable reference targets for normalization of reverse transcription-qPCR data in mice.

scientific article

Expression of the E-cadherin-catenin complex in lung neuroendocrine tumours

scientific article published on 01 May 2001

From neural crest cells to melanocytes: cellular plasticity during development and beyond

scientific article published on 04 March 2019

Functional and molecular characterization of the epithelioid to round transition in human colorectal cancer LoVo cells.

scientific article published on October 2003

Gene expression profiling to dissect the complexity of cancer biology: pitfalls and promise

scientific article published on 07 March 2012

Genetic characterization and therapeutic targeting of MYC-rearranged T cell acute lymphoblastic leukaemia

scientific article published on 25 June 2018

Genomic organization of the human beta-catenin gene (CTNNB1).

scientific article

Heterocellular 3D scaffolds as biomimetic to recapitulate the tumor microenvironment of peritoneal metastases in vitro and in vivo.

scientific article published on 23 December 2017

Human decellularized dermal matrix seeded with adipose-derived stem cells enhances wound healing in a murine model: Experimental study

scientific article published on 07 August 2019

Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression

scientific article

Identification of eleven novel tumor-associated E-cadherin mutations. Mutations in brief no. 215. Online

scientific article published on 01 January 1999

Identification of excretory-secretory products of larval and adult Ostertagia ostertagi by immunoscreening of cDNA libraries

scientific article

Identification of potential protective antigens of Ostertagia ostertagi with local antibody probes

scientific article published in October 2002

Identification of putative cancer genes through data integration and comparative genomics between plants and humans.

scientific article

Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection

scientific article published on 03 January 2020

Interplay between KLF4 and ZEB2/SIP1 in the regulation of E-cadherin expression ⬇️

scientific article published on January 29, 2013

Involvement of members of the cadherin superfamily in cancer

scientific article

Isolation and characterization of a human pseudogene (CTNNAP1) for alpha E-catenin (CTNNA1): assignment of the pseudogene to 5q22 and the alpha E-catenin gene to 5q31.

scientific article published on March 1995

Key signalling nodes in mammary gland development and cancer. The Snail1-Twist1 conspiracy in malignant breast cancer progression

scientific article

LIN28B is over-expressed in specific subtypes of pediatric leukemia and regulates lncRNA H19.

scientific article published on 11 March 2016

Localization of the 17q breakpoint of a constitutional 1;17 translocation in a patient with neuroblastoma within a 25-kb segment located between the ACCN1 and TLK2 genes and near the distal breakpoints of two microdeletions in neurofibromatosis type

scientific article

Melanoma cells revive an embryonic transcriptional network to dictate phenotypic heterogeneity.

scientific article published on 09 December 2014

Modulation of iron transport proteins in human colorectal carcinogenesis

scientific article

Module network inference from a cancer gene expression data set identifies microRNA regulated modules

scientific article

Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Mature Pigmented Melanocytes

scientific article published on 4 October 2017

Mutations of the human E-cadherin (CDH1) gene

scientific article published in January 1998

NBPF1, a tumor suppressor candidate in neuroblastoma, exerts growth inhibitory effects by inducing a G1 cell cycle arrest.

scientific article

Nanos genes and their role in development and beyond.

scientific article

Novel strategy for rapid functional in vivo validation of oncogenic drivers in haematological malignancies

scientific article published on 22 July 2019

Oncogenic ZEB2 activation drives sensitivity toward KDM1A inhibition in T-cell acute lymphoblastic leukemia

scientific article published on 9 January 2017

Pre-EMTing metastasis? Recapitulation of morphogenetic processes in cancer.

scientific article published on 3 November 2007

Proteolytic cleavage of beta-catenin by caspases: an in vitro analysis

scientific article published in September 1999

Regulation of p63 isoforms by snail and slug transcription factors in human squamous cell carcinoma

scientific article

Regulation of vimentin by SIP1 in human epithelial breast tumor cells.

scientific article published on 27 March 2006

Regulatory networks defining EMT during cancer initiation and progression

scientific article published on February 2013

SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell-cell junctions

scientific article

Simultaneous loss of E-cadherin and catenins in invasive lobular breast cancer and lobular carcinomain situ ⬇️

scientific article published on December 1, 1997

Smad4 induces the tumor suppressor E-cadherin and P-cadherin in colon carcinoma cells

scientific article published on 01 September 2002

Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium

scientific article published on 10 March 2015

Snail in the frame of malignant tumor recurrence

scientific article published on January 2006

Snail promotes Wnt target gene expression and interacts with beta-catenin

scientific article published on 12 May 2008

Strategies for immortalization of primary hepatocytes

scientific article

Structure-function Studies in Mouse Embryonic Stem Cells Using Recombinase-mediated Cassette Exchange.

scientific article published on 27 April 2017

Targeting BET proteins improves the therapeutic efficacy of BCL-2 inhibition in T-cell acute lymphoblastic leukemia.

scientific article published on 11 January 2017

Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection

scientific article

The E-cadherin-repressed hNanos1 gene induces tumor cell invasion by upregulating MT1-MMP expression

scientific article

The E-cadherin/catenin complex: an important gatekeeper in breast cancer tumorigenesis and malignant progression

scientific article

The EMT regulator Zeb2/Sip1 is essential for murine embryonic hematopoietic stem/progenitor cell differentiation and mobilization

scientific article published on 25 February 2011

The MCM-binding protein ETG1 aids sister chromatid cohesion required for postreplicative homologous recombination repair

scientific article

The Role of Epithelial-to-Mesenchymal Plasticity in Ovarian Cancer Progression and Therapy Resistance

scientific article published on 17 June 2019

The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages

scientific article published on 31 July 2018

The cell-cell adhesion molecule E-cadherin.

scientific article

The role of the E-cadherin/catenin adhesion complex in the development and progression of cancer.

scientific article

The role of the ZEB family of transcription factors in development and disease.

scientific article published on March 2009

The transcription factor Zeb2 regulates development of conventional and plasmacytoid DCs by repressing Id2

scientific article published on 16 May 2016

The transcription factor snail induces tumor cell invasion through modulation of the epithelial cell differentiation program.

scientific article

The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion

scientific article (publication date: June 2001)

Tissue Factor Induced by Epithelial-Mesenchymal Transition Triggers a Procoagulant State That Drives Metastasis of Circulating Tumor Cells

scientific article published on 24 May 2016

Transforming growth factor-beta and mutant p53 conspire to induce metastasis by antagonizing p63: a (ternary) complex affair

scientific article published on 27 July 2009

Transforming growth factor-beta1-mediated Slug and Snail transcription factor up-regulation reduces the density of Langerhans cells in epithelial metaplasia by affecting E-cadherin expression

scientific article published on April 2008

Transition from the noninvasive to the invasive phenotype and loss of alpha-catenin in human colon cancer cells.

scientific article published on October 1995

Tumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells.

scientific article published on 2 April 2015

USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia

scientific article published on 17 September 2018

VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and snail

scientific article published on 23 October 2006

Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity

scientific article published on 30 March 2016

Xenogen-free isolation and culture of human adipose mesenchymal stem cells

scientific article published on 08 August 2019

ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling.

scientific article

ZEB2 in T-cells and T-ALL

scientific article published on 27 July 2019

ZEB2 stably represses RAB25 expression through epigenetic regulation by SIRT1 and DNMTs during epithelial-to-mesenchymal transition

scientific article published on 16 November 2018

ZEB2-transgene expression in the epidermis compromises the integrity of the epidermal barrier through the repression of different tight junction proteins

scientific article published on 27 February 2014

Zeb2 Regulates Cell Fate at the Exit from Epiblast State in Mouse Embryonic Stem Cells

scientific article

p120 Catenin-Mediated Stabilization of E-Cadherin Is Essential for Primitive Endoderm Specification

scientific article

Paulina is supported by:

About Paulina

Help