List of works - Jan Stenvang

A novel dual-target steroid sulfatase inhibitor and antiestrogen: SR 16157, a promising agent for the therapy of breast cancer.

scientific article published in February 2007

A phase II study of weekly irinotecan in patients with locally advanced or metastatic HER2- negative breast cancer and increased copy numbers of the topoisomerase 1 (TOP1) gene: a study protocol

scientific article

A systematic review on topoisomerase 1 inhibition in the treatment of metastatic breast cancer ⬇️

scientific article published on March 20, 2013

ABCG2 Protein Levels and Association to Response to First-Line Irinotecan-Based Therapy for Patients with Metastatic Colorectal Cancer

scientific article published on 16 July 2020

Acquisition of docetaxel resistance in breast cancer cells reveals upregulation of ABCB1 expression as a key mediator of resistance accompanied by discrete upregulation of other specific genes and pathways

scientific article

Activation of ErbB3, EGFR and Erk is essential for growth of human breast cancer cell lines with acquired resistance to fulvestrant

scientific article published on 14 April 2008

An Explorative Analysis of ABCG2/TOP-1 mRNA Expression as a Biomarker Test for FOLFIRI Treatment in Stage III Colon Cancer Patients: Results from Retrospective Analyses of the PETACC-3 Trial

scientific article published on 15 April 2020

Biomarker-guided repurposing of chemotherapeutic drugs for cancer therapy: a novel strategy in drug development.

scientific article published on 25 December 2013

Breast cancer cells with acquired antiestrogen resistance are sensitized to cisplatin-induced cell death

scientific article

Detection of serological biomarkers by proximity extension assay for detection of colorectal neoplasias in symptomatic individuals

scientific article published on 10 October 2013

Drug transporters in breast cancer: response to anthracyclines and taxanes.

scientific article published on September 2015

Establishment and characterization of models of chemotherapy resistance in colorectal cancer: Towards a predictive signature of chemoresistance

scientific article

Gel-Based Proteomics of Clinical Samples Identifies Potential Serological Biomarkers for Early Detection of Colorectal Cancer

scientific article published on 02 December 2019

High expression of microRNA-625-3p is associated with poor response to first-line oxaliplatin based treatment of metastatic colorectal cancer.

scientific article

Homogenous 96-plex PEA immunoassay exhibiting high sensitivity, specificity, and excellent scalability

scientific article

Implications of ABCG2 Expression on Irinotecan Treatment of Colorectal Cancer Patients: A Review.

scientific article published on 7 September 2017

Induction of cell death in antiestrogen resistant human breast cancer cells by the protein kinase CK2 inhibitor DMAT.

scientific article

Inhibition of microRNA function by antimiR oligonucleotides

scientific article

Integrative analyses of gene expression and DNA methylation profiles in breast cancer cell line models of tamoxifen-resistance indicate a potential role of cells with stem-like properties

scientific article

Measuring ERCC1 protein expression in cancer specimens: validation of a novel antibody

scientific article

Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer

scientific article published on 25 September 2015

MiR-155 is overexpressed in patients with atopic dermatitis and modulates T-cell proliferative responses by targeting cytotoxic T lymphocyte-associated antigen 4.

scientific article

MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo

scientific article

MicroRNAs, epigenetics and disease ⬇️

scientific article published on September 20, 2010

Multiplexed homogeneous proximity ligation assays for high-throughput protein biomarker research in serological material

scientific article

No effect of ablation of surfactant protein-D on acute cerebral infarction in mice

scientific article

Plasma levels of the MMP-9:TIMP-1 complex as prognostic biomarker in breast cancer: a retrospective study

scientific article

Progesterone receptor isoform A may regulate the effects of neoadjuvant aglepristone in canine mammary carcinoma

scientific article

Progesterone receptor isoform analysis by quantitative real-time polymerase chain reaction in formalin-fixed, paraffin-embedded canine mammary dysplasias and tumors

scientific article

Protein Kinase C alpha is a marker for antiestrogen resistance and is involved in the growth of tamoxifen resistant human breast cancer cells

scientific article published on 24 October 2006

Proximity probing assays for simultaneous visualization of protein complexes in situ.

scientific article published in June 2013

Purification and characterization of bioactive his6-tagged recombinant human tissue inhibitor of metalloproteinases-1 (TIMP-1) protein expressed at high yields in mammalian cells.

scientific article

Reversal of ABCG2/BCRP-Mediated Multidrug Resistance by 5,3',5'-Trihydroxy-3,6,7,4'-Tetramethoxyflavone Isolated from the Australian Desert Plant Chinnock

scientific article published in 2021

Silencing of microRNA families by seed-targeting tiny LNAs

scientific article published on 20 March 2011

Silencing of microRNA-155 in mice during acute inflammatory response leads to derepression of c/ebp Beta and down-regulation of G-CSF

scientific article

TIMP-1 Increases Expression and Phosphorylation of Proteins Associated with Drug Resistance in Breast Cancer Cells

scientific article (publication date: 6 September 2013)

TIMP1 overexpression mediates resistance of MCF-7 human breast cancer cells to fulvestrant and down-regulates progesterone receptor expression.

scientific article

TOP1 gene copy numbers are increased in cancers of the bile duct and pancreas

article

Targeting of microRNAs for therapeutics.

scientific article published in December 2008

The Therapeutic Potential of MicroRNAs in Cancer ⬇️

scientific article published on May 1, 2012

The glutamate transport inhibitor DL-Threo-β-Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells.

scientific article published on 16 May 2015

The potential role of Alu Y in the development of resistance to SN38 (Irinotecan) or oxaliplatin in colorectal cancer

scientific article published on 22 May 2015

The utility of LNA in microRNA-based cancer diagnostics and therapeutics

scientific article published on 15 January 2008

Topoisomerase-1 and -2A gene copy numbers are elevated in mismatch repair-proficient colorectal cancers

scientific article published on 04 March 2015

Topoisomerase-1 gene copy aberrations are frequent in patients with breast cancer.

scientific article

List of works by Jan Stenvang

A novel dual-target steroid sulfatase inhibitor and antiestrogen: SR 16157, a promising agent for the therapy of breast cancer.

A phase II study of weekly irinotecan in patients with locally advanced or metastatic HER2- negative breast cancer and increased copy numbers of the topoisomerase 1 (TOP1) gene: a study protocol

A systematic review on topoisomerase 1 inhibition in the treatment of metastatic breast cancer ⬇️

ABCG2 Protein Levels and Association to Response to First-Line Irinotecan-Based Therapy for Patients with Metastatic Colorectal Cancer

Acquisition of docetaxel resistance in breast cancer cells reveals upregulation of ABCB1 expression as a key mediator of resistance accompanied by discrete upregulation of other specific genes and pathways

Activation of ErbB3, EGFR and Erk is essential for growth of human breast cancer cell lines with acquired resistance to fulvestrant

An Explorative Analysis of ABCG2/TOP-1 mRNA Expression as a Biomarker Test for FOLFIRI Treatment in Stage III Colon Cancer Patients: Results from Retrospective Analyses of the PETACC-3 Trial

Biomarker-guided repurposing of chemotherapeutic drugs for cancer therapy: a novel strategy in drug development.

Breast cancer cells with acquired antiestrogen resistance are sensitized to cisplatin-induced cell death

Detection of serological biomarkers by proximity extension assay for detection of colorectal neoplasias in symptomatic individuals

Drug transporters in breast cancer: response to anthracyclines and taxanes.

Establishment and characterization of models of chemotherapy resistance in colorectal cancer: Towards a predictive signature of chemoresistance

Gel-Based Proteomics of Clinical Samples Identifies Potential Serological Biomarkers for Early Detection of Colorectal Cancer

High expression of microRNA-625-3p is associated with poor response to first-line oxaliplatin based treatment of metastatic colorectal cancer.

Homogenous 96-plex PEA immunoassay exhibiting high sensitivity, specificity, and excellent scalability

Implications of ABCG2 Expression on Irinotecan Treatment of Colorectal Cancer Patients: A Review.

Induction of cell death in antiestrogen resistant human breast cancer cells by the protein kinase CK2 inhibitor DMAT.

Inhibition of microRNA function by antimiR oligonucleotides

Integrative analyses of gene expression and DNA methylation profiles in breast cancer cell line models of tamoxifen-resistance indicate a potential role of cells with stem-like properties

Measuring ERCC1 protein expression in cancer specimens: validation of a novel antibody

Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer

MiR-155 is overexpressed in patients with atopic dermatitis and modulates T-cell proliferative responses by targeting cytotoxic T lymphocyte-associated antigen 4.

MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo

MicroRNAs, epigenetics and disease ⬇️

Multiplexed homogeneous proximity ligation assays for high-throughput protein biomarker research in serological material

No effect of ablation of surfactant protein-D on acute cerebral infarction in mice

Plasma levels of the MMP-9:TIMP-1 complex as prognostic biomarker in breast cancer: a retrospective study

Progesterone receptor isoform A may regulate the effects of neoadjuvant aglepristone in canine mammary carcinoma

Progesterone receptor isoform analysis by quantitative real-time polymerase chain reaction in formalin-fixed, paraffin-embedded canine mammary dysplasias and tumors

Protein Kinase C alpha is a marker for antiestrogen resistance and is involved in the growth of tamoxifen resistant human breast cancer cells

Proximity probing assays for simultaneous visualization of protein complexes in situ.

Purification and characterization of bioactive his6-tagged recombinant human tissue inhibitor of metalloproteinases-1 (TIMP-1) protein expressed at high yields in mammalian cells.

Reversal of ABCG2/BCRP-Mediated Multidrug Resistance by 5,3',5'-Trihydroxy-3,6,7,4'-Tetramethoxyflavone Isolated from the Australian Desert Plant Chinnock

Silencing of microRNA families by seed-targeting tiny LNAs

Silencing of microRNA-155 in mice during acute inflammatory response leads to derepression of c/ebp Beta and down-regulation of G-CSF

TIMP-1 Increases Expression and Phosphorylation of Proteins Associated with Drug Resistance in Breast Cancer Cells

TIMP1 overexpression mediates resistance of MCF-7 human breast cancer cells to fulvestrant and down-regulates progesterone receptor expression.

TOP1 gene copy numbers are increased in cancers of the bile duct and pancreas

Targeting of microRNAs for therapeutics.

The Therapeutic Potential of MicroRNAs in Cancer ⬇️

The glutamate transport inhibitor DL-Threo-β-Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells.

The potential role of Alu Y in the development of resistance to SN38 (Irinotecan) or oxaliplatin in colorectal cancer

The utility of LNA in microRNA-based cancer diagnostics and therapeutics

Topoisomerase-1 and -2A gene copy numbers are elevated in mismatch repair-proficient colorectal cancers

Topoisomerase-1 gene copy aberrations are frequent in patients with breast cancer.