List of works - Brigitte Sola

4-Hydroxy-tamoxifen-loaded liposomes have potent anti-myeloma activity

scientific article published on 8 January 2013

A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress.

scientific article published on 10 August 2017

A mouse model of disseminated mantle cell lymphoma highlights a lack of activity of estrogen receptor β agonists toward tumor burden

scientific article

A sensitive method to quantify senescent cancer cells.

scientific article published on 2 August 2013

Anti-tumor necrosis factor-alpha (TNF-alpha) treatment strategies in Crohn's disease

scientific article published on February 2007

Antiestrogenic therapies in solid cancers and multiple myeloma.

scientific article published on June 2006

Antioestrogen-mediated cell cycle arrest and apoptosis induction in breast cancer and multiple myeloma cells.

scientific article published on March 2008

Antitumoral activity of lenalidomide in in vitro and in vivo models of mantle cell lymphoma involves the destabilization of cyclin D1/p27KIP1 complexes

scientific article published on 31 October 2013

Apoptotic death in cortical neurons of mice subjected to focal ischemia

scientific article published on 01 October 1996

Cooperation between structural elements in hormonoregulated transcription from the mouse mammary tumor virus promoter ⬇️

scientific article published on April 11, 1991

Cyclin D1 Inhibits Mitochondrial Activity in B Cells ⬇️

scientific article published on February 22, 2011

Cyclin D1 expression in patients with multiple myeloma

scientific article published in 2000

Cyclin D1 gene activation in human myeloma cells is independent of DNA hypomethylation or histone hyperacetylation.

scientific article

Cyclin D1 regulates p27(Kip1) stability in B cells.

scientific article published on 15 September 2010

Cyclin D1 sensitizes myeloma cells to endoplasmic reticulum stress-mediated apoptosis by activating the unfolded protein response pathway

scientific article published on 11 April 2015

Cyclin D1 targets hexokinase 2 to control aerobic glycolysis in myeloma cells

scientific article published on 24 July 2020

Cyclin D1 unbalances the redox status controlling cell adhesion, migration, and drug resistance in myeloma cells.

scientific article published on 7 June 2016

Cyclin K and cyclin D1b are oncogenic in myeloma cells.

scientific article

Cytoplasmic cyclin D1 controls the migration and invasiveness of mantle lymphoma cells.

scientific article published on 24 October 2017

Deazaneplanocin a is a promising drug to kill multiple myeloma cells in their niche

scientific article

Deciphering Genetic Alterations of Hairy Cell Leukemia and Hairy Cell Leukemia-like Disorders in 98 Patients

scientific article published on 10 April 2022

Detection by the comet assay of apoptosis induced in lymphoid cell lines after growth factor deprivation.

scientific article

Differential regulation of NMDA receptor-expressing neurons in the rat hippocampus and striatum following bilateral vestibular loss demonstrated using flow cytometry

scientific article published on 21 June 2018

Dysfunction of the Fas apoptotic signaling pathway in persistent polyclonal B-cell lymphocytosis.

scientific article published in February 2003

Early and sequential recruitment of apoptotic effectors after focal permanent ischemia in mice

scientific article published in February 2000

Early involvement of the fim-2 and fim-3 regions in mouse myeloblastic leukemogenesis.

scientific article published in December 1988

Ectopic expression of cyclin D1 impairs the proliferation and enhances the apoptosis of a murine lymphoid cell line.

scientific article published on January 2001

Estrogenic or antiestrogenic therapies for multiple myeloma?

scientific article published on 24 September 2007

Expression and subcellular localization of cyclin-dependent kinase inhibitor p27 does not correlate with proliferation pattern of mantle lymphoma cells.

scientific article published on 6 February 2014

Expression of cyclins D-type in B-chronic lymphoproliferative disorders

scientific article published in July 2000

Expression of functional β-platelet-derived growth factor receptors on hematopoietic cell lines

scientific article published in January 1993

Expression of the two alternative [a] and [b] transcripts of CCND1 gene in cyclin D1-expressing B-malignancies: relevance for the pathogenesis.

scientific article

Fim-1, Fim-2/c-fms, and Fim-3, three common integration sites of Friend murine leukemia virus in myeloblastic leukemias, map to mouse chromosomes 13, 18, and 3, respectively

scientific article published on November 1988

Flow cytometry for receptor analysis from ex-vivo brain tissue in adult rat

scientific article published on 13 April 2018

Frequent c-fms activation by proviral insertion in mouse myeloblastic leukaemias.

scientific article

Growth arrest and terminal differentiation of leukemic myelomonocytic cells induced through ligation of surface CD23 antigen.

scientific article published on November 1994

HIF-1α and rapamycin act as gerosuppressant in multiple myeloma cells upon genotoxic stress.

scientific article published on 24 June 2016

Heat shock factor 1 is a potent therapeutic target for enhancing the efficacy of treatments for multiple myeloma with adverse prognosis.

scientific article published on 23 April 2015

Hemolytic anemia and erythroleukemia, two distinct pathogenic effects of Friend MuLV: Mapping of the effects to different regions of the viral genome

scientific article published on 01 December 1986

High sensitivity of protoplasmic cortical astroglia to focal ischemia.

scientific article published in March 2002

In vitro evaluation of B-CLL cells apoptotic responses to irradiation.

scientific article published on June 1999

Influence of debris and aggregates on image cytometry DNA measurement of archival tumors

scientific article published in April 1997

Isolation and characterization of a monoclonal antibody specific for fibrinogen and fibrin of human origin.

scientific article

Lipospermine-mediated gene transfer technique into murine cultured cortical cells.

scientific article

Malignant myeloblastic transformation of murine long-term bone marrow cultures by F-MuLV:In vitro reproduction of a long-term leukemogenesis, and investigation of preleukemic events

scientific article published on 15 August 1983

Management of Drug Resistance in Mantle Cell Lymphoma

scientific article published on 12 June 2020

Monoclonal antibodies against human factor VIII molecular neutralize antihemophilic factor and ristocetin cofactor activities.

scientific article

Multistep virus-induced leukemogenesis in vitro: description of a model specifying three steps within the myeloblastic malignant process.

scientific article published on January 1984

New generation sequencing of targeted genes in the classical and the variant form of hairy cell leukemia highlights mutations in epigenetic regulation genes.

scientific article published on 22 June 2018

Overproduction of Cu/Zn-superoxide dismutase or Bcl-2 prevents the brain mitochondrial respiratory dysfunction induced by glutathione depletion.

scientific article

Pharmacological delta1- and delta2-opioid receptor subtypes in the human neuroblastoma cell line SK-N-BE: no evidence for distinct molecular entities.

scientific article

Pure antiestrogen-induced G1-arrest in myeloma cells results from the reduced kinase activity of cyclin D3/CDK6 complexes whereas apoptosis is mediated by endoplasmic reticulum-dependent caspases.

scientific article

ROS Overproduction Sensitises Myeloma Cells to Bortezomib-Induced Apoptosis and Alleviates Tumour Microenvironment-Mediated Cell Resistance

scientific article published on 26 October 2020

Reassessment of the murine c-fms proto-oncogene sequence.

scientific article

Recruitment of several neuroprotective pathways after permanent focal ischemia in mice

scientific article published in December 1998

Recurrent mutations of the exportin 1 gene (XPO1) and their impact on selective inhibitor of nuclear export compounds sensitivity in primary mediastinal B-cell lymphoma

scientific article published on 16 June 2016

Reduction of cell proliferation and potentiation of Fas-induced apoptosis by the selective kappa-opioid receptor agonist U50 488 in the multiple myeloma LP-1 cells

scientific article

Reduction of cortical infarction and impairment of apoptosis in NGF-transgenic mice subjected to permanent focal ischemia

scientific article published in March 1998

Reduction of ischemic damage in NGF-transgenic mice: correlation with enhancement of antioxidant enzyme activities.

scientific article published on June 1999

Relevance of cyclin D1 level in the pathogenesis of multiple myeloma

scientific article published on 01 December 2003

Relevance of cyclin D1b expression and CCND1 polymorphism in the pathogenesis of multiple myeloma and mantle cell lymphoma

scientific article

STAT6 is a cargo of exportin 1: Biological relevance in primary mediastinal B-cell lymphoma.

scientific article

Senescence-associated secretory phenotype favors the emergence of cancer stem-like cells.

scientific article published on 20 December 2012

Somatostatin and opioid receptors do not regulate proliferation or apoptosis of the human multiple myeloma U266 cells

scientific article published on 7 June 2009

The double dealing of cyclin D1

scientific article published on 29 December 2019

The enigmatic role of cyclin D1 in multiple myeloma.

scientific article

The human homologues of Fim1, Fim2/c-Fms, and Fim3, three retroviral integration regions involved in mouse myeloblastic leukemias, are respectively located on chromosomes 6p23, 5q33, and 3q27

scientific article published in February 1989

The targeting of the sole cyclin D1 is not adequate for mantle cell lymphoma and myeloma therapies.

scientific article published on 13 August 2009

Transcriptional and post-transcriptional mechanisms induce cyclin-D1 over-expression in B-chronic lymphoproliferative disorders

scientific article published on 8 October 1999

Upstream mediators of the Fas apoptotic transduction pathway are defective in B-chronic lymphocytic leukemia.

scientific article

Viral expression in two myelomonocytic cell lines obtained from long-term bone marrow culture infected with the Friend polycythemia-inducing virus (FV-P).

scientific article

XPO1 in B cell hematological malignancies: from recurrent somatic mutations to targeted therapy.

scientific article published on 14 February 2017

XPO1E571K Mutation Modifies Exportin 1 Localisation and Interactome in B-cell Lymphoma

scientific article published on 30 September 2020

[18F]Fludarabine-PET in a murine model of multiple myeloma

scientific article

[Emergence of cancer stem cells or tumor-initiating/propagating cells and relapse in multiple myeloma]

scientific article published on 01 December 2014

[Monoclonal antibodies against the factor VIII/Willebrand factor molecule: inhibition of the cofactor action of ristocetin and the antihemophilic factor]

scientific article published on 18 May 1981

c-Jun and cyclin D1 proteins as mediators of neuronal death after a focal ischaemic insult.

scientific article

List of works by Brigitte Sola

4-Hydroxy-tamoxifen-loaded liposomes have potent anti-myeloma activity

A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress.

A mouse model of disseminated mantle cell lymphoma highlights a lack of activity of estrogen receptor β agonists toward tumor burden

A sensitive method to quantify senescent cancer cells.

Anti-tumor necrosis factor-alpha (TNF-alpha) treatment strategies in Crohn's disease

Antiestrogenic therapies in solid cancers and multiple myeloma.

Antioestrogen-mediated cell cycle arrest and apoptosis induction in breast cancer and multiple myeloma cells.

Antitumoral activity of lenalidomide in in vitro and in vivo models of mantle cell lymphoma involves the destabilization of cyclin D1/p27KIP1 complexes

Apoptotic death in cortical neurons of mice subjected to focal ischemia

Cooperation between structural elements in hormonoregulated transcription from the mouse mammary tumor virus promoter ⬇️

Cyclin D1 Inhibits Mitochondrial Activity in B Cells ⬇️

Cyclin D1 expression in patients with multiple myeloma

Cyclin D1 gene activation in human myeloma cells is independent of DNA hypomethylation or histone hyperacetylation.

Cyclin D1 regulates p27(Kip1) stability in B cells.

Cyclin D1 sensitizes myeloma cells to endoplasmic reticulum stress-mediated apoptosis by activating the unfolded protein response pathway

Cyclin D1 targets hexokinase 2 to control aerobic glycolysis in myeloma cells

Cyclin D1 unbalances the redox status controlling cell adhesion, migration, and drug resistance in myeloma cells.

Cyclin K and cyclin D1b are oncogenic in myeloma cells.

Cytoplasmic cyclin D1 controls the migration and invasiveness of mantle lymphoma cells.

Deazaneplanocin a is a promising drug to kill multiple myeloma cells in their niche

Deciphering Genetic Alterations of Hairy Cell Leukemia and Hairy Cell Leukemia-like Disorders in 98 Patients

Detection by the comet assay of apoptosis induced in lymphoid cell lines after growth factor deprivation.

Differential regulation of NMDA receptor-expressing neurons in the rat hippocampus and striatum following bilateral vestibular loss demonstrated using flow cytometry

Dysfunction of the Fas apoptotic signaling pathway in persistent polyclonal B-cell lymphocytosis.

Early and sequential recruitment of apoptotic effectors after focal permanent ischemia in mice

Early involvement of the fim-2 and fim-3 regions in mouse myeloblastic leukemogenesis.

Ectopic expression of cyclin D1 impairs the proliferation and enhances the apoptosis of a murine lymphoid cell line.

Estrogenic or antiestrogenic therapies for multiple myeloma?

Expression and subcellular localization of cyclin-dependent kinase inhibitor p27 does not correlate with proliferation pattern of mantle lymphoma cells.

Expression of cyclins D-type in B-chronic lymphoproliferative disorders

Expression of functional β-platelet-derived growth factor receptors on hematopoietic cell lines

Expression of the two alternative [a] and [b] transcripts of CCND1 gene in cyclin D1-expressing B-malignancies: relevance for the pathogenesis.

Fim-1, Fim-2/c-fms, and Fim-3, three common integration sites of Friend murine leukemia virus in myeloblastic leukemias, map to mouse chromosomes 13, 18, and 3, respectively

Flow cytometry for receptor analysis from ex-vivo brain tissue in adult rat

Frequent c-fms activation by proviral insertion in mouse myeloblastic leukaemias.

Growth arrest and terminal differentiation of leukemic myelomonocytic cells induced through ligation of surface CD23 antigen.

HIF-1α and rapamycin act as gerosuppressant in multiple myeloma cells upon genotoxic stress.

Heat shock factor 1 is a potent therapeutic target for enhancing the efficacy of treatments for multiple myeloma with adverse prognosis.

Hemolytic anemia and erythroleukemia, two distinct pathogenic effects of Friend MuLV: Mapping of the effects to different regions of the viral genome

High sensitivity of protoplasmic cortical astroglia to focal ischemia.

In vitro evaluation of B-CLL cells apoptotic responses to irradiation.

Influence of debris and aggregates on image cytometry DNA measurement of archival tumors

Isolation and characterization of a monoclonal antibody specific for fibrinogen and fibrin of human origin.

Lipospermine-mediated gene transfer technique into murine cultured cortical cells.

Malignant myeloblastic transformation of murine long-term bone marrow cultures by F-MuLV:In vitro reproduction of a long-term leukemogenesis, and investigation of preleukemic events

Management of Drug Resistance in Mantle Cell Lymphoma

Monoclonal antibodies against human factor VIII molecular neutralize antihemophilic factor and ristocetin cofactor activities.

Multistep virus-induced leukemogenesis in vitro: description of a model specifying three steps within the myeloblastic malignant process.

New generation sequencing of targeted genes in the classical and the variant form of hairy cell leukemia highlights mutations in epigenetic regulation genes.

Overproduction of Cu/Zn-superoxide dismutase or Bcl-2 prevents the brain mitochondrial respiratory dysfunction induced by glutathione depletion.

Pharmacological delta1- and delta2-opioid receptor subtypes in the human neuroblastoma cell line SK-N-BE: no evidence for distinct molecular entities.

Pure antiestrogen-induced G1-arrest in myeloma cells results from the reduced kinase activity of cyclin D3/CDK6 complexes whereas apoptosis is mediated by endoplasmic reticulum-dependent caspases.

ROS Overproduction Sensitises Myeloma Cells to Bortezomib-Induced Apoptosis and Alleviates Tumour Microenvironment-Mediated Cell Resistance

Reassessment of the murine c-fms proto-oncogene sequence.

Recruitment of several neuroprotective pathways after permanent focal ischemia in mice

Recurrent mutations of the exportin 1 gene (XPO1) and their impact on selective inhibitor of nuclear export compounds sensitivity in primary mediastinal B-cell lymphoma

Reduction of cell proliferation and potentiation of Fas-induced apoptosis by the selective kappa-opioid receptor agonist U50 488 in the multiple myeloma LP-1 cells

Reduction of cortical infarction and impairment of apoptosis in NGF-transgenic mice subjected to permanent focal ischemia

Reduction of ischemic damage in NGF-transgenic mice: correlation with enhancement of antioxidant enzyme activities.

Relevance of cyclin D1 level in the pathogenesis of multiple myeloma

Relevance of cyclin D1b expression and CCND1 polymorphism in the pathogenesis of multiple myeloma and mantle cell lymphoma

STAT6 is a cargo of exportin 1: Biological relevance in primary mediastinal B-cell lymphoma.

Senescence-associated secretory phenotype favors the emergence of cancer stem-like cells.

Somatostatin and opioid receptors do not regulate proliferation or apoptosis of the human multiple myeloma U266 cells

The double dealing of cyclin D1

The enigmatic role of cyclin D1 in multiple myeloma.

The human homologues of Fim1, Fim2/c-Fms, and Fim3, three retroviral integration regions involved in mouse myeloblastic leukemias, are respectively located on chromosomes 6p23, 5q33, and 3q27

The targeting of the sole cyclin D1 is not adequate for mantle cell lymphoma and myeloma therapies.

Transcriptional and post-transcriptional mechanisms induce cyclin-D1 over-expression in B-chronic lymphoproliferative disorders

Upstream mediators of the Fas apoptotic transduction pathway are defective in B-chronic lymphocytic leukemia.

Viral expression in two myelomonocytic cell lines obtained from long-term bone marrow culture infected with the Friend polycythemia-inducing virus (FV-P).

XPO1 in B cell hematological malignancies: from recurrent somatic mutations to targeted therapy.

XPO1E571K Mutation Modifies Exportin 1 Localisation and Interactome in B-cell Lymphoma

[18F]Fludarabine-PET in a murine model of multiple myeloma

[Emergence of cancer stem cells or tumor-initiating/propagating cells and relapse in multiple myeloma]

[Monoclonal antibodies against the factor VIII/Willebrand factor molecule: inhibition of the cofactor action of ristocetin and the antihemophilic factor]

c-Jun and cyclin D1 proteins as mediators of neuronal death after a focal ischaemic insult.