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List of works by Ku-lung Hsu

A lectin microarray approach for the rapid analysis of bacterial glycans

article

A simple strategy for the creation of a recombinant lectin microarray

scientific article

ABHD6 blockade exerts antiepileptic activity in PTZ-induced seizures and in spontaneous seizures in R6/2 mice

scientific article

Analyzing the dynamic bacterial glycome with a lectin microarray approach.

scientific article

Automated Spatially Targeted Optical Microproteomics (autoSTOMP) to Determine Protein Complexity of Subcellular Structures

scientific article published on 07 January 2020

Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors

scientific article

Combined inhibition of FAAH and COX produces enhanced anti-allodynic effects in mouse neuropathic and inflammatory pain models

scientific article

Competitive activity-based protein profiling identifies aza-β-lactams as a versatile chemotype for serine hydrolase inhibition

scientific article published on 8 March 2012

Confirming target engagement for reversible inhibitors in vivo by kinetically tuned activity-based probes

scientific article

DAGL-Beta Functions as a PUFA-Specific Triacylglycerol Lipase in Macrophages

scientific article published on 27 January 2020

DAGLβ inhibition perturbs a lipid network involved in macrophage inflammatory responses

scientific article

Deconstructing Lipid Kinase Inhibitors by Chemical Proteomics

scientific article published on 20 November 2017

Development and optimization of piperidyl-1,2,3-triazole ureas as selective chemical probes of endocannabinoid biosynthesis

scientific article published on 23 October 2013

Diacylglycerol Lipase-β Is Required for TNF-α Response but Not CD8+ T Cell Priming Capacity of Dendritic Cells

scientific article published on 16 May 2019

Diacylglycerol lipase disinhibits VTA dopamine neurons during chronic nicotine exposure

scientific article published on 11 January 2016

Diacylglycerol lipase β inhibition reverses nociceptive behaviour in mouse models of inflammatory and neuropathic pain.

scientific article published on 24 February 2016

Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective, and in vivo-active inhibitors of α/β-hydrolase domain containing 6 (ABHD6)

scientific article published on 23 October 2013

Evaluation of different drug classes on transient sciatic nerve injury-depressed marble burying in mice

scientific article published on 8 March 2018

Fabrication of an oriented lectin microarray

scientific article published in June 2010

Global targeting of functional tyrosines using sulfur-triazole exchange chemistry

scientific article published on 25 November 2019

Highly Selective, Reversible Inhibitor Identified by Comparative Chemoproteomics Modulates Diacylglycerol Lipase Activity in Neurons

scientific article published on July 2015

Identification of the major prostaglandin glycerol ester hydrolase in human cancer cells

scientific article

Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes

scientific article

Isoform-selective activity-based profiling of ERK signaling

Lacritin proteoforms prevent tear film collapse and maintain epithelial homeostasis

scientific article published on 13 November 2020

Liganding Functional Tyrosine Sites on Proteins Using Sulfur-Triazole Exchange Chemistry

scientific article published on 24 April 2020

Liposomal Delivery of Diacylglycerol Lipase-Beta Inhibitors to Macrophages Dramatically Enhances Selectivity and Efficacy in Vivo

scientific article published on 13 September 2017

Mapping posttranscriptional regulation of the human glycome uncovers microRNA defining the glycocode

scientific article published on 03 March 2014

Modulation of PKM activity affects the differentiation of TH17 cells

scientific article published on 27 October 2020

Monoacylglycerol lipase inhibitors reverse paclitaxel-induced nociceptive behavior and proinflammatory markers in a mouse model of chemotherapy-induced neuropathy

scientific article published on 14 March 2018

Next-Generation Cell-Active Inhibitors of the Undrugged Oncogenic PTP4A3 Phosphatase

scientific article published on 10 October 2019

Ratiometric lectin microarray analysis of the mammalian cell surface glycome

scientific article published on January 2011

Re-examining the potential of targeting ABHD6 in multiple sclerosis: Efficacy of systemic and peripherally restricted inhibitors in experimental autoimmune encephalomyelitis

scientific article published on 30 August 2018

Recombinant lectin microarrays for glycomic analysis

scientific article published on January 2011

Regulation of calcium release from the endoplasmic reticulum by the serine hydrolase ABHD2.

scientific article published on 3 July 2017

Reprogramming fatty acyl specificity of lipid kinases via C1 domain engineering

scientific article published on 13 January 2020

Selective inhibitor of platelet-activating factor acetylhydrolases 1b2 and 1b3 that impairs cancer cell survival

scientific article

Selective inhibitors and tailored activity probes for lipoprotein-associated phospholipase A(2)

scientific article published on 2 December 2012

Serine hydrolase inhibitors block necrotic cell death by preventing calcium overload of the mitochondria and permeability transition pore formation

scientific article published on 02 December 2013

Sweet tasting chips: microarray-based analysis of glycans

scientific article published on 26 August 2009

The Ligand Binding Landscape of Diacylglycerol Kinases

scientific article published on 6 July 2017

The hereditary spastic paraplegia-related enzyme DDHD2 is a principal brain triglyceride lipase

scientific journal article

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