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List of works by Akiyoshi Uemura

A new perfusion culture method with a self-organized capillary network

scientific article published on 28 October 2020

A sodium-glucose cotransporter 2 inhibitor attenuates renal capillary injury and fibrosis by a vascular endothelial growth factor-dependent pathway after renal injury in mice

scientific article published on 23 July 2018

Angiogenesis in the mouse retina: a model system for experimental manipulation

scientific article

Arhgef15 promotes retinal angiogenesis by mediating VEGF-induced Cdc42 activation and potentiating RhoJ inactivation in endothelial cells

scientific article

Autonomy and Non-autonomy of Angiogenic Cell Movements Revealed by Experiment-Driven Mathematical Modeling

scientific article published on 19 November 2015

Cataract-preventing contact lens for in vivo imaging of mouse retina

scientific article published on 01 August 2018

Combination therapy with intravitreal tissue plasminogen activator and ranibizumab for subfoveal type 2 choroidal neovascularization

scientific article published on 26 February 2016

Corneal spherical aberration of eyes with cataract in a Japanese population

scientific article published on 01 June 2010

Endosomal sorting by Semaphorin 4A in retinal pigment epithelium supports photoreceptor survival

scientific article published on 30 March 2012

EphrinB2-EphB4 signals regulate formation and maintenance of funnel-shaped valves in corneal lymphatic capillaries

scientific article published on 12 June 2013

FGD5 mediates proangiogenic action of vascular endothelial growth factor in human vascular endothelial cells.

scientific article published on 9 February 2012

Flattening of retinal pigment epithelial detachments after pneumatic displacement of submacular hemorrhages secondary to age-related macular degeneration

scientific article published on 01 July 2018

High level of endothelial cell-specific gene expression by a combination of the 5' flanking region and the 5' half of the first intron of the VE-cadherin gene

scientific article published on 3 March 2005

Identification of novel drug targets for the treatment of diabetic retinopathy

scientific article

Indocyanine Green Angiography-Guided Focal Laser Photocoagulation for Diabetic Macular Edema

scientific article published on 23 September 2015

Inhibition of stromal cell-derived factor-1α/CXCR4 signaling restores the blood-retina barrier in pericyte-deficient mouse retinas

MRP4 knockdown enhances migration, suppresses apoptosis, and produces aggregated morphology in human retinal vascular endothelial cells.

scientific article published on 6 September 2010

Mechanisms of endothelial cell coverage by pericytes: computational modelling of cell wrapping and in vitro experiments

scientific article published on 29 January 2020

Microaneurysms cause refractory macular edema in branch retinal vein occlusion

scientific article

Microvascular Abnormalities on Optical Coherence Tomography Angiography in Macular Edema Associated With Branch Retinal Vein Occlusion

scientific article published on 28 October 2015

Multimodal evaluation of an interphotoreceptor retinoid-binding protein-induced mouse model of experimental autoimmune uveitis

scientific article published on 09 March 2022

Pathophysiology of Diabetic Retinopathy: The Old and the New

Pharmacologic management of diabetic retinopathy

scientific article published on 6 September 2017

Phosphatidylinositol 3-kinase/Akt regulates angiotensin II-induced inhibition of apoptosis in microvascular endothelial cells by governing survivin expression and suppression of caspase-3 activity

scientific article published on 12 February 2004

PlexinD1 signaling controls morphological changes and migration termination in newborn neurons.

scientific article published on 18 January 2018

Recombinant angiopoietin-1 restores higher-order architecture of growing blood vessels in mice in the absence of mural cells.

scientific article

Remodeling mechanisms determine size distributions in developing retinal vasculature

scientific article published on 14 October 2020

Retinal Hemodynamics Seen on Optical Coherence Tomography Angiography Before and After Treatment of Retinal Vein Occlusion

scientific article

RhoJ Regulates α5β1 Integrin Trafficking to Control Fibronectin Remodeling during Angiogenesis

scientific article published on 08 April 2020

RhoJ integrates attractive and repulsive cues in directional migration of endothelial cells

scientific article published on 29 April 2020

Selective induction of neuropilin-1 by vascular endothelial growth factor (VEGF): a mechanism contributing to VEGF-induced angiogenesis

scientific article

Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenesis in ischemic retinopathy in mice

scientific article published on April 18, 2011

Semaphorin 3E/PlexinD1 signaling is required for cardiac ventricular compaction

scientific article published on 22 August 2019

Semaphorin 3G Provides a Repulsive Guidance Cue to Lymphatic Endothelial Cells via Neuropilin-2/PlexinD1.

scientific article published in November 2016

Semaphorin-3C signals through Neuropilin-1 and PlexinD1 receptors to inhibit pathological angiogenesis.

scientific article

Semaphorin3E-induced inflammation contributes to insulin resistance in dietary obesity

scientific article published on 01 October 2013

Sequential Notch activation regulates ventricular chamber development

scientific article

Structural and Functional Analyses of Retinal Ischemia in Eyes with Retinal Vein Occlusion: Relationship with Macular Edema or Microaneurysm Formation

article

Sustained inflammation after pericyte depletion induces irreversible blood-retina barrier breakdown

scientific article (publication date: 9 February 2017)

Sympathetic ophthalmia in fellow eye after vitrectomy for massive subretinal hemorrhage secondary to polypoidal choroidal vasculopathy

scientific article published on 30 October 2018

TLX activates MASH1 for induction of neuronal lineage commitment of adult hippocampal neuroprogenitors

scientific article

The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice

scientific journal article

Therapeutic potential of semaphorin 3E for the treatment of choroidal neovascularization

scientific article

Tlx acts as a proangiogenic switch by regulating extracellular assembly of fibronectin matrices in retinal astrocytes

scientific journal article

Tlx, an orphan nuclear receptor, regulates cell numbers and astrocyte development in the developing retina

scientific journal article

Transcription factor Ets-1 mediates ischemia- and vascular endothelial growth factor-dependent retinal neovascularization.

scientific article published on May 2004

Transient expression of ephrin b2 in perinatal skin is required for maintenance of keratinocyte homeostasis

scientific journal article

Ursodeoxycholic Acid Attenuates the Retinal Vascular Abnormalities in Anti-PDGFR-β Antibody-Induced Pericyte Depletion Mouse Models

scientific article published on 22 January 2020

Vascular RhoJ is an effective and selective target for tumor angiogenesis and vascular disruption

scientific article published in January 2014