List of works - John Challiss

"Phenotypic" pharmacology: the influence of cellular environment on G protein-coupled receptor antagonist and inverse agonist pharmacology.

scientific article published on 12 September 2006

A model for Ca2+ oscillations stimulated by the type 5 metabotropic glutamate receptor: an unusual mechanism based on repetitive, reversible phosphorylation of the receptor

scientific article published on 17 September 2011

A problem in the radiochemical assay of glucose-6-phosphatase in muscle ⬇️

scientific article published on March 1, 1984

A single point mutation (N514Y) in the human M3 muscarinic acetylcholine receptor reveals differences in the properties of antagonists: evidence for differential inverse agonism.

scientific article published on 17 February 2006

Altered M(1) muscarinic acetylcholine receptor (CHRM1)-Galpha(q/11) coupling in a schizophrenia endophenotype

scientific article published on 29 April 2009

An Antibody Biosensor Establishes the Activation of the M1 Muscarinic Acetylcholine Receptor during Learning and Memory

scientific article published on 29 January 2016

Arrestins 2 and 3 differentially regulate ETA and P2Y2 receptor-mediated cell signaling and migration in arterial smooth muscle.

scientific article published on 7 December 2011

Arrestins differentially regulate histamine- and oxytocin-evoked phospholipase C and mitogen-activated protein kinase signalling in myometrial cells.

scientific article

Biased M1-muscarinic-receptor-mutant mice inform the design of next-generation drugs

scientific article published on 20 February 2020

Biosynthetic infochemical communication.

scientific article published on 09 July 2015

Ca2+/calmodulin-dependent translocation of sphingosine kinase: role in plasma membrane relocation but not activation.

scientific article published on February 2003

Characterization of an atypical muscarinic cholinoceptor mediating contraction of the guinea-pig isolated uterus.

scientific article

Characterization of anandamide-stimulated cannabinoid receptor signaling in human ULTR myometrial smooth muscle cells.

scientific article published on 28 May 2009

Characterization of the adenosine receptor modulating insulin action in rat skeletal muscle

scientific article published on 01 June 1992

Clustered coding variants in the glutamate receptor complexes of individuals with schizophrenia and bipolar disorder

scientific article

Comparative effects of BRL 38227, nitrendipine and isoprenaline on carbachol- and histamine-stimulated phosphoinositide metabolism in airway smooth muscle ⬇️

scientific article published on April 1, 1992

Comparison of the effect of isobutylmethylxanthine and phosphodiesterase-selective inhibitors on cAMP levels in SH-SY5Y neuroblastoma cells ⬇️

scientific article published on June 22, 1993

Conformational analysis of cyclophostin and designed analogs in comparison with the potent IP3 receptor agonist adenophostin A.

scientific article published in January 2001

Constitutive activity and inverse agonism at the M2 muscarinic acetylcholine receptor

scientific article published on 27 September 2005

Defining the roles of arrestin2 and arrestin3 in vasoconstrictor receptor desensitization in hypertension.

scientific article published on 13 May 2015

Depolarization and Agonist-Stimulated Changes in Inositol 1,4,5-Trisphosphate and Inositol 1,3,4,5-Tetrakisphosphate Mass Accumulation in Rat Cerebral Cortex ⬇️

scientific article published on September 1, 1991

Differential Regulation of Muscarinic Acetylcholine Receptor-sensitive Polyphosphoinositide Pools and Consequences for Signaling in Human Neuroblastoma Cells ⬇️

scientific article published on February 27, 1998

Differential expression and regulation of ryanodine receptor and myo-inositol 1,4,5-trisphosphate receptor Ca2+ release channels in mammalian tissues and cell lines ⬇️

scientific article published on October 1, 1997

Differential regulation of β2-adrenoceptor and adenosine A2B receptor signalling by GRK and arrestin proteins in arterial smooth muscle

scientific article published on 31 July 2018

Disruption of phosphoinositide signalling by lithium

scientific article published on May 1, 1992

Distinct and complementary roles for α and β isoenzymes of PKC in mediating vasoconstrictor responses to acutely elevated glucose

scientific article published on 9 December 2015

Early failure of N-methyl-D-aspartate receptors and deficient spine formation induced by reduction of regulatory heme in neurons.

scientific article

Effect of endurance and sprint exercise on the sensitivity of glucose metabolism to insulin in the epitrochlearis muscle of sedentary and trained rats

scientific article published on 01 January 1991

Effects of positive allosteric modulators on single-cell oscillatory Ca2+ signaling initiated by the type 5 metabotropic glutamate receptor.

scientific article

Effects of varying the expression level of recombinant human mGlu1alpha receptors on the pharmacological properties of agonists and antagonists

scientific article published in February 1999

Endogenous G protein-coupled receptor kinase 6 Regulates M3 muscarinic acetylcholine receptor phosphorylation and desensitization in human SH-SY5Y neuroblastoma cells

scientific article (publication date: 3 May 2002)

Endothelin signalling in arterial smooth muscle is tightly regulated by G protein-coupled receptor kinase 2.

scientific article published on 11 September 2009

Enhanced Type 1α Metabotropic Glutamate Receptor-Stimulated Phosphoinositide Signaling after Pertussis Toxin Treatment ⬇️

scientific article published on September 1, 1997

Enhanced inducible mGlu1alpha receptor expression in Chinese hamster ovary cells

scientific article published in June 2001

Enhanced purinoceptor-mediated Ca2+ signalling in L-fibroblasts overexpressing type 1 inositol 1,4,5-trisphosphate receptors.

scientific article published on August 1999

Evidence for cross‐talk between M2 and M3 muscarinic acetylcholine receptors in the regulation of second messenger and extracellular signal‐regulated kinase signalling pathways in Chinese hamster ovary cells ⬇️

scientific article published on April 1, 2003

FRET-based detection of M1 muscarinic acetylcholine receptor activation by orthosteric and allosteric agonists

scientific article

Functional selectivity of muscarinic receptor antagonists for inhibition of M3-mediated phosphoinositide responses in guinea pig urinary bladder and submandibular salivary gland.

scientific article

G protein coupling and signaling pathway activation by m1 muscarinic acetylcholine receptor orthosteric and allosteric agonists.

scientific article published on 29 July 2008

G protein-coupled receptor kinases 3 and 6 use different pathways to desensitize the endogenous M3 muscarinic acetylcholine receptor in human SH-SY5Y cells

scientific article published in August 2001

G protein-coupled receptor signalling in astrocytes in health and disease: a focus on metabotropic glutamate receptors

scientific article

Group I metabotropic glutamate receptors, mGlu1a and mGlu5a, couple to cyclic AMP response element binding protein (CREB) through a common Ca2+ - and protein kinase C-dependent pathway

scientific article

Group-I metabotropic glutamate receptors, mGlu1a and mGlu5a, couple to extracellular signal-regulated kinase (ERK) activation via distinct, but overlapping, signalling pathways

scientific article published in December 2002

Growth inhibition by the muscarinic M(3) acetylcholine receptor: evidence for p21(Cip1/Waf1) involvement in G(1) arrest.

scientific article published on October 2002

HMGB1 is upregulated in the airways in asthma and potentiates airway smooth muscle contraction via TLR4.

scientific article published on 23 February 2017

Imaging of muscarinic acetylcholine receptor signaling in hippocampal neurons: evidence for phosphorylation-dependent and -independent regulation by G-protein-coupled receptor kinases.

scientific article published in April 2004

Increased nicotinamide adenine dinucleotide phosphate oxidase 4 expression mediates intrinsic airway smooth muscle hypercontractility in asthma

scientific article published on 22 November 2011

Inhibitory action of the potassium channel opener BRL 38227 on agonist-stimulated phosphoinositide metabolism in bovine tracheal smooth muscle

scientific article published on 01 January 1992

Insulin sensitivity of rates of glycolysis and glycogen synthesis in soleus, stripped soleus, epitrochlearis, and hemi-diaphragm muscles isolated from sedentary rats ⬇️

scientific article published on 01 July 1983

Intracellular signalling. Receptor-specific messenger oscillations

scientific article published in September 2001

Lack of effect of zaprinast on methacholine-induced contraction and inositol 1,4,5-trisphosphate accumulation in bovine tracheal smooth muscle ⬇️

scientific article published on May 1, 1991

Ligand-Specific Signaling Profiles and Resensitization Mechanisms of the Neuromedin U2 Receptor.

scientific article published on 3 May 2018

Lithium-induced disruption of cell signalling in brain: evidence implicating the phosphoinositide cycle

scientific article published on January 1, 1992

Long-term channel block is required to inhibit cellular transformation by human ether-à-go-go-related gene (hERG1) potassium channels.

scientific article

M3 muscarinic cholinoceptors are linked to phosphoinositide metabolism in rat cerebellar granule cells ⬇️

scientific article published on March 25, 1991

Maximal activities of hexokinase, 6-phosphofructokinase, oxoglutarate dehydrogenase, and carnitine palmitoyltransferase in rat and avian muscles ⬇️

scientific article published on 01 December 1983

Mechanisms underlying the neuronal calcium sensor-1-evoked enhancement of exocytosis in PC12 cells

scientific journal article

Modulation of Gq-protein-coupled inositol trisphosphate and Ca2+ signaling by the membrane potential

scientific article published on September 2006

Modulation of spasmogen-stimulated Ins(1,4,5)P3 generation and functional responses by selective inhibitors of types 3 and 4 phosphodiesterase in airways smooth muscle

scientific article published in May 1998

Muscarinic acetylcholine receptor activation enhances hippocampal neuron excitability and potentiates synaptically evoked Ca(2+) signals via phosphatidylinositol 4,5-bisphosphate depletion

scientific article published in September 2005

NMDA-receptor regulation of muscarinic-receptor stimulated inositol 1,4,5-trisphosphate production and protein kinase C activation in single cerebellar granule neurons.

scientific article

Neuronal muscarinic receptors and phosphoinositide metabolism ⬇️

scientific article published on April 1, 1991

Nitric oxide is a volume transmitter regulating postsynaptic excitability at a glutamatergic synapse

scientific article published in November 2008

Nitric oxide synthesis and cGMP production is important for neurite growth and synapse remodeling after axotomy.

scientific article published in March 2013

Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability.

scientific article published on 9 April 2018

No evidence for altered intracellular calcium-handling in airway smooth muscle cells from human subjects with asthma

scientific article

Novel structural and functional insights into M3 muscarinic receptor dimer/oligomer formation

scientific article published on 16 October 2013

Pharmacological assessment of m1 muscarinic acetylcholine receptor-gq/11 protein coupling in membranes prepared from postmortem human brain tissue

scientific article published on 5 March 2008

Pharmacological characterization of type 1alpha metabotropic glutamate receptor-stimulated [35S]-GTPgammaS binding.

scientific article published on July 1997

Principal role of adenylyl cyclase 6 in K⁺ channel regulation and vasodilator signalling in vascular smooth muscle cells.

scientific article published on 23 May 2011

Quantitation of the lithium-sensitive component of the muscarinic receptor-stimulated inositol 1,3,4,5-tetrakisphosphate response in rat cerebral cortex

scientific article published on May 1, 1992

Reassessment of the Ca2+ sensing property of a type I metabotropic glutamate receptor by simultaneous measurement of inositol 1,4,5-trisphosphate and Ca2+ in single cells.

scientific article published on 20 February 2001

Receptors: GPCR-G protein preassembly?

scientific article published on 19 September 2011

Regulation of brain capillary endothelial cells by P2Y receptors coupled to Ca2+, phospholipase C and mitogen‐activated protein kinase ⬇️

scientific article published on November 1, 1997

Regulation of cyclic AMP response-element binding-protein (CREB) by Gq/11-protein-coupled receptors in human SH-SY5Y neuroblastoma cells

scientific article published on 22 October 2007

Regulation of oxytocin receptor responsiveness by G protein-coupled receptor kinase 6 in human myometrial smooth muscle

scientific article

Regulation of phosphoinositide turnover in neonatal rat cerebral cortex by group I‐ and II‐ selective metabotropic glutamate receptor agonists ⬇️

scientific article published on February 1, 1998

Role of Ca2+ feedback on single cell inositol 1,4,5-trisphosphate oscillations mediated by G-protein-coupled receptors.

scientific article published on April 2003

Role of protein kinase C in the regulation of histamine and bradykinin stimulated inositol polyphosphate turnover in adrenal chromaffin cells ⬇️

scientific article published on December 1, 1992

Roles of phosphorylation-dependent and -independent mechanisms in the regulation of M1 muscarinic acetylcholine receptors by G protein-coupled receptor kinase 2 in hippocampal neurons.

scientific article

Selective regulation of H1 histamine receptor signaling by G protein-coupled receptor kinase 2 in uterine smooth muscle cells.

scientific article

Single cell analysis and temporal profiling of agonist-mediated inositol 1,4,5-trisphosphate, Ca2+, diacylglycerol, and protein kinase C signaling using fluorescent biosensors.

scientific article

Small-Molecule G Protein-Coupled Receptor Kinase Inhibitors Attenuate G Protein-Coupled Receptor Kinase 2-Mediated Desensitization of Vasoconstrictor-Induced Arterial Contractions

scientific article published on 06 July 2018

Specificity of g protein-coupled receptor kinase 6-mediated phosphorylation and regulation of single-cell m3 muscarinic acetylcholine receptor signaling

scientific article published on November 2003

Steady-state modulation of voltage-gated K+ channels in rat arterial smooth muscle by cyclic AMP-dependent protein kinase and protein phosphatase 2B

scientific article

Structural aspects of M₃ muscarinic acetylcholine receptor dimer formation and activation

scientific article published on 26 October 2011

Structural, signalling and regulatory properties of the group I metabotropic glutamate receptors: prototypic family C G-protein-coupled receptors

scientific article

Sugar transport asymmetry in human erythrocytes--the effect of bulk haemoglobin removal and the addition of methylxanthines

scientific article published on 01 October 1980

Synaptic activity augments muscarinic acetylcholine receptor-stimulated inositol 1,4,5-trisphosphate production to facilitate Ca2+ release in hippocampal neurons

scientific article published in September 2004

Temporal profiling of changes in phosphatidylinositol 4,5-bisphosphate, inositol 1,4,5-trisphosphate and diacylglycerol allows comprehensive analysis of phospholipase C-initiated signalling in single neurons.

scientific article

The Use of Translocating Fluorescent Biosensors for Real-Time Monitoring of GPCR-Mediated Signaling Events ⬇️

scientific article published on January 1, 2011

The effects of insulin on transport and metabolism of glucose in skeletal muscle from hyperthyroid and hypothyroid rats ⬇️

scientific article published on 01 June 1997

The regulation of M1 muscarinic acetylcholine receptor desensitization by synaptic activity in cultured hippocampal neurons

scientific journal article

Treatment of experimental NADH ubiquinone reductase deficiency with menadione

scientific article published on August 1, 1992

Visualizing the temporal effects of vasoconstrictors on PKC translocation and Ca2+ signaling in single resistance arterial smooth muscle cells

scientific article published in October 2008

[Ca2+]i oscillations in ASM: relationship with persistent airflow obstruction in asthma

scientific article

List of works by John Challiss

"Phenotypic" pharmacology: the influence of cellular environment on G protein-coupled receptor antagonist and inverse agonist pharmacology.

A model for Ca2+ oscillations stimulated by the type 5 metabotropic glutamate receptor: an unusual mechanism based on repetitive, reversible phosphorylation of the receptor

A problem in the radiochemical assay of glucose-6-phosphatase in muscle ⬇️

A single point mutation (N514Y) in the human M3 muscarinic acetylcholine receptor reveals differences in the properties of antagonists: evidence for differential inverse agonism.

Altered M(1) muscarinic acetylcholine receptor (CHRM1)-Galpha(q/11) coupling in a schizophrenia endophenotype

An Antibody Biosensor Establishes the Activation of the M1 Muscarinic Acetylcholine Receptor during Learning and Memory

Arrestins 2 and 3 differentially regulate ETA and P2Y2 receptor-mediated cell signaling and migration in arterial smooth muscle.

Arrestins differentially regulate histamine- and oxytocin-evoked phospholipase C and mitogen-activated protein kinase signalling in myometrial cells.

Biased M1-muscarinic-receptor-mutant mice inform the design of next-generation drugs

Biosynthetic infochemical communication.

Ca2+/calmodulin-dependent translocation of sphingosine kinase: role in plasma membrane relocation but not activation.

Characterization of an atypical muscarinic cholinoceptor mediating contraction of the guinea-pig isolated uterus.

Characterization of anandamide-stimulated cannabinoid receptor signaling in human ULTR myometrial smooth muscle cells.

Characterization of the adenosine receptor modulating insulin action in rat skeletal muscle

Clustered coding variants in the glutamate receptor complexes of individuals with schizophrenia and bipolar disorder

Comparative effects of BRL 38227, nitrendipine and isoprenaline on carbachol- and histamine-stimulated phosphoinositide metabolism in airway smooth muscle ⬇️

Comparison of the effect of isobutylmethylxanthine and phosphodiesterase-selective inhibitors on cAMP levels in SH-SY5Y neuroblastoma cells ⬇️

Conformational analysis of cyclophostin and designed analogs in comparison with the potent IP3 receptor agonist adenophostin A.

Constitutive activity and inverse agonism at the M2 muscarinic acetylcholine receptor

Defining the roles of arrestin2 and arrestin3 in vasoconstrictor receptor desensitization in hypertension.

Depolarization and Agonist-Stimulated Changes in Inositol 1,4,5-Trisphosphate and Inositol 1,3,4,5-Tetrakisphosphate Mass Accumulation in Rat Cerebral Cortex ⬇️

Differential Regulation of Muscarinic Acetylcholine Receptor-sensitive Polyphosphoinositide Pools and Consequences for Signaling in Human Neuroblastoma Cells ⬇️

Differential expression and regulation of ryanodine receptor and myo-inositol 1,4,5-trisphosphate receptor Ca2+ release channels in mammalian tissues and cell lines ⬇️

Differential regulation of β2-adrenoceptor and adenosine A2B receptor signalling by GRK and arrestin proteins in arterial smooth muscle

Disruption of phosphoinositide signalling by lithium

Distinct and complementary roles for α and β isoenzymes of PKC in mediating vasoconstrictor responses to acutely elevated glucose

Early failure of N-methyl-D-aspartate receptors and deficient spine formation induced by reduction of regulatory heme in neurons.

Effect of endurance and sprint exercise on the sensitivity of glucose metabolism to insulin in the epitrochlearis muscle of sedentary and trained rats

Effects of positive allosteric modulators on single-cell oscillatory Ca2+ signaling initiated by the type 5 metabotropic glutamate receptor.

Effects of varying the expression level of recombinant human mGlu1alpha receptors on the pharmacological properties of agonists and antagonists

Endogenous G protein-coupled receptor kinase 6 Regulates M3 muscarinic acetylcholine receptor phosphorylation and desensitization in human SH-SY5Y neuroblastoma cells

Endothelin signalling in arterial smooth muscle is tightly regulated by G protein-coupled receptor kinase 2.

Enhanced Type 1α Metabotropic Glutamate Receptor-Stimulated Phosphoinositide Signaling after Pertussis Toxin Treatment ⬇️

Enhanced inducible mGlu1alpha receptor expression in Chinese hamster ovary cells

Enhanced purinoceptor-mediated Ca2+ signalling in L-fibroblasts overexpressing type 1 inositol 1,4,5-trisphosphate receptors.

Evidence for cross‐talk between M2 and M3 muscarinic acetylcholine receptors in the regulation of second messenger and extracellular signal‐regulated kinase signalling pathways in Chinese hamster ovary cells ⬇️

FRET-based detection of M1 muscarinic acetylcholine receptor activation by orthosteric and allosteric agonists

Functional selectivity of muscarinic receptor antagonists for inhibition of M3-mediated phosphoinositide responses in guinea pig urinary bladder and submandibular salivary gland.

G protein coupling and signaling pathway activation by m1 muscarinic acetylcholine receptor orthosteric and allosteric agonists.

G protein-coupled receptor kinases 3 and 6 use different pathways to desensitize the endogenous M3 muscarinic acetylcholine receptor in human SH-SY5Y cells

G protein-coupled receptor signalling in astrocytes in health and disease: a focus on metabotropic glutamate receptors

Group I metabotropic glutamate receptors, mGlu1a and mGlu5a, couple to cyclic AMP response element binding protein (CREB) through a common Ca2+ - and protein kinase C-dependent pathway

Group-I metabotropic glutamate receptors, mGlu1a and mGlu5a, couple to extracellular signal-regulated kinase (ERK) activation via distinct, but overlapping, signalling pathways

Growth inhibition by the muscarinic M(3) acetylcholine receptor: evidence for p21(Cip1/Waf1) involvement in G(1) arrest.

HMGB1 is upregulated in the airways in asthma and potentiates airway smooth muscle contraction via TLR4.

Imaging of muscarinic acetylcholine receptor signaling in hippocampal neurons: evidence for phosphorylation-dependent and -independent regulation by G-protein-coupled receptor kinases.

Increased nicotinamide adenine dinucleotide phosphate oxidase 4 expression mediates intrinsic airway smooth muscle hypercontractility in asthma

Inhibitory action of the potassium channel opener BRL 38227 on agonist-stimulated phosphoinositide metabolism in bovine tracheal smooth muscle

Insulin sensitivity of rates of glycolysis and glycogen synthesis in soleus, stripped soleus, epitrochlearis, and hemi-diaphragm muscles isolated from sedentary rats ⬇️

Intracellular signalling. Receptor-specific messenger oscillations

Lack of effect of zaprinast on methacholine-induced contraction and inositol 1,4,5-trisphosphate accumulation in bovine tracheal smooth muscle ⬇️

Ligand-Specific Signaling Profiles and Resensitization Mechanisms of the Neuromedin U2 Receptor.

Lithium-induced disruption of cell signalling in brain: evidence implicating the phosphoinositide cycle

Long-term channel block is required to inhibit cellular transformation by human ether-à-go-go-related gene (hERG1) potassium channels.

M3 muscarinic cholinoceptors are linked to phosphoinositide metabolism in rat cerebellar granule cells ⬇️

Maximal activities of hexokinase, 6-phosphofructokinase, oxoglutarate dehydrogenase, and carnitine palmitoyltransferase in rat and avian muscles ⬇️

Mechanisms underlying the neuronal calcium sensor-1-evoked enhancement of exocytosis in PC12 cells

Modulation of Gq-protein-coupled inositol trisphosphate and Ca2+ signaling by the membrane potential

Modulation of spasmogen-stimulated Ins(1,4,5)P3 generation and functional responses by selective inhibitors of types 3 and 4 phosphodiesterase in airways smooth muscle

Muscarinic acetylcholine receptor activation enhances hippocampal neuron excitability and potentiates synaptically evoked Ca(2+) signals via phosphatidylinositol 4,5-bisphosphate depletion

NMDA-receptor regulation of muscarinic-receptor stimulated inositol 1,4,5-trisphosphate production and protein kinase C activation in single cerebellar granule neurons.

Neuronal muscarinic receptors and phosphoinositide metabolism ⬇️

Nitric oxide is a volume transmitter regulating postsynaptic excitability at a glutamatergic synapse

Nitric oxide synthesis and cGMP production is important for neurite growth and synapse remodeling after axotomy.

Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability.

No evidence for altered intracellular calcium-handling in airway smooth muscle cells from human subjects with asthma

Novel structural and functional insights into M3 muscarinic receptor dimer/oligomer formation

Pharmacological assessment of m1 muscarinic acetylcholine receptor-gq/11 protein coupling in membranes prepared from postmortem human brain tissue

Pharmacological characterization of type 1alpha metabotropic glutamate receptor-stimulated [35S]-GTPgammaS binding.

Principal role of adenylyl cyclase 6 in K⁺ channel regulation and vasodilator signalling in vascular smooth muscle cells.

Quantitation of the lithium-sensitive component of the muscarinic receptor-stimulated inositol 1,3,4,5-tetrakisphosphate response in rat cerebral cortex

Reassessment of the Ca2+ sensing property of a type I metabotropic glutamate receptor by simultaneous measurement of inositol 1,4,5-trisphosphate and Ca2+ in single cells.

Receptors: GPCR-G protein preassembly?

Regulation of brain capillary endothelial cells by P2Y receptors coupled to Ca2+, phospholipase C and mitogen‐activated protein kinase ⬇️

Regulation of cyclic AMP response-element binding-protein (CREB) by Gq/11-protein-coupled receptors in human SH-SY5Y neuroblastoma cells

Regulation of oxytocin receptor responsiveness by G protein-coupled receptor kinase 6 in human myometrial smooth muscle

Regulation of phosphoinositide turnover in neonatal rat cerebral cortex by group I‐ and II‐ selective metabotropic glutamate receptor agonists ⬇️

Role of Ca2+ feedback on single cell inositol 1,4,5-trisphosphate oscillations mediated by G-protein-coupled receptors.

Role of protein kinase C in the regulation of histamine and bradykinin stimulated inositol polyphosphate turnover in adrenal chromaffin cells ⬇️