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List of works by Yoshikazu Takada

A T cell-binding fragment of fibrinogen can prevent autoimmunity

scientific article

A dominant-negative FGF1 mutant (the R50E mutant) suppresses tumorigenesis and angiogenesis

scientific journal article

A novel fibroblast growth factor-1 (FGF1) mutant that acts as an FGF antagonist

scientific article

ADAM12-mediated focal adhesion formation is differently regulated by beta1 and beta3 integrins

scientific article published on 28 September 2005

ADAM12/syndecan-4 signaling promotes beta 1 integrin-dependent cell spreading through protein kinase Calpha and RhoA.

scientific article

Adhesion of gastric carcinoma cells to peritoneum mediated by alpha3beta1 integrin (VLA-3).

scientific article published on September 2004

Altered rate of fibronectin matrix assembly by deletion of the first type III repeats

scientific article

Amino acid residues in the alpha IIb subunit that are critical for ligand binding to integrin alpha IIbbeta 3 are clustered in the beta-propeller model

scientific article published on 13 September 2001

An integrin binding-defective mutant of insulin-like growth factor-1 (R36E/R37E IGF1) acts as a dominant-negative antagonist of the IGF1 receptor (IGF1R) and suppresses tumorigenesis but still binds to IGF1R.

scientific article published on 21 May 2013

Attachment of human colon cancer cells to vascular endothelium is enhanced by N-acetylglucosaminyltransferase V.

scientific article published in January 2004

Cellular interaction of integrin alpha3beta1 with laminin 5 promotes gap junctional communication

scientific article

Changing Ligand Specificities of αvβ1 and αvβ3 Integrins by Swapping a Short Diverse Sequence of the β Subunit

scientific article published in Journal of Biological Chemistry

Chinese hamster ovary cells expressing alpha4beta1 integrin stimulate osteoclast formation in vitro.

scientific article published on August 1998

Combinatorial chemistry identifies high-affinity peptidomimetics against alpha4beta1 integrin for in vivo tumor imaging

scientific article published on 11 June 2006

Critical cysteine residues for regulation of integrin alphaIIbbeta3 are clustered in the epidermal growth factor domains of the beta3 subunit

scientific article published on March 2004

Critical residues for ligand binding in an I domain-like structure of the integrin beta1 subunit

scientific article published in August 1996

Critical residues of integrin alphaIIb subunit for binding of alphaIIbbeta3 (glycoprotein IIb-IIIa) to fibrinogen and ligand-mimetic antibodies (PAC-1, OP-G2, and LJ-CP3).

scientific article

Critical role of integrin alpha 5 beta 1 in urokinase (uPA)/urokinase receptor (uPAR, CD87) signaling

scientific article published on 15 May 2003

Critical threonine and aspartic acid residues within the I domains of beta 2 integrins for interactions with intercellular adhesion molecule 1 (ICAM-1) and C3bi

scientific article published in May 1995

Cross-talk between integrin α6β4 and insulin-like growth factor-1 receptor (IGF1R) through direct α6β4 binding to IGF1 and subsequent α6β4-IGF1-IGF1R ternary complex formation in anchorage-independent conditions

scientific journal article

Cross-talk of integrin alpha3beta1 and tissue factor in cell migration

scientific article published on 14 July 2004

Defining the Topology of Integrin α5β1-Fibronectin Interactions Using Inhibitory Anti-α5 and Anti-β1 Monoclonal Antibodies

scientific article published in Journal of Biological Chemistry

Determinants of the specificity of rotavirus interactions with the alpha2beta1 integrin

scientific article

Differential regulation of cellular adhesion and migration by recombinant laminin-5 forms with partial deletion or mutation within the G3 domain of alpha3 chain

scientific article published on February 2003

Direct binding of integrin alphavbeta3 to FGF1 plays a role in FGF1 signaling

scientific article

Direct binding of the EGF-like domain of neuregulin-1 to integrins ({alpha}v{beta}3 and {alpha}6{beta}4) is involved in neuregulin-1/ErbB signaling

scientific journal article

Direct integrin binding to insulin-like growth factor-2 through the C-domain is required for insulin-like growth factor receptor type 1 (IGF1R) signaling.

scientific article

Direct interaction of the kringle domain of urokinase-type plasminogen activator (uPA) and integrin alpha v beta 3 induces signal transduction and enhances plasminogen activation

scientific article published in March 2006

Discovery of targeting ligands for breast cancer cells using the one-bead one-compound combinatorial method

scientific article

Echovirus 1 interaction with the human very late antigen-2 (integrin alpha2beta1) I domain. Identification of two independent virus contact sites distinct from the metal ion-dependent adhesion site

scientific article published in November 1997

Effects of fibronectin cleaved by neuropsin on cell adhesion and migration.

scientific article

Effects on rotavirus cell binding and infection of monomeric and polymeric peptides containing alpha2beta1 and alphaxbeta2 integrin ligand sequences

scientific article

Enhanced Expression of Integrin αvβ3 Induced by TGF-β Is Required for the Enhancing Effect of Fibroblast Growth Factor 1 (FGF1) in TGF-β-Induced Epithelial-Mesenchymal Transition (EMT) in Mammary Epithelial Cells

scientific article published on 3 September 2015

Enhanced activity of transforming growth factor β1 (TGF-β1) bound to cartilage oligomeric matrix protein

scientific article published on 22 September 2011

Enzymatic and immunological comparison of alanine: glyoxylate aminotransferases from different fish and mammalian livers

scientific article published on 01 January 1984

Erratum to “A T cell-binding fragment of fibrinogen can prevent autoimmunity” [J. Autoimmun. 34 (2010) 453–459]

scholarly article published in Journal of Autoimmunity

Expression level of integrin alpha 5 on tumour cells affects the rate of metastasis to the kidney

scientific article published on January 2003

Fibrinogen-gamma C-terminal fragments induce endothelial barrier dysfunction and microvascular leak via integrin-mediated and RhoA-dependent mechanism

scientific article

Fibulin-5/DANCE is essential for elastogenesis in vivo

scientific article (publication date: 10 January 2002)

Functional classification of ADAMs based on a conserved motif for binding to integrin alpha 9beta 1: implications for sperm-egg binding and other cell interactions

scientific article (publication date: 17 May 2002)

Galectin-3 modulates phagocytosis-induced stellate cell activation and liver fibrosis in vivo ⬇️

scientific article published on December 8, 2011

Glutamate-Glyoxylate Aminotransferase in Rat Liver Cytosol. Purification, Properties and Identity with Alanine-2-Oxoglutarate Aminotransferase

scientific article published in 1977

High affinity interactions of Coxsackievirus A9 with integrin alphavbeta3 (CD51/61) require the CYDMKTTC sequence of beta3, but do not require the RGD sequence of the CAV-9 VP1 protein.

scientific article

Human parechovirus 1 utilizes integrins alphavbeta3 and alphavbeta1 as receptors

scientific article

Identification of Equine Lactadherin-derived Peptides That Inhibit Rotavirus Infection via Integrin Receptor Competition

scientific article published on 26 March 2015

Identification of inhibitors against interaction between pro-inflammatory sPLA2-IIA protein and integrin αvβ3 ⬇️

scientific article published on October 24, 2012

Identification of proteins that associate with integrin α2 by proteomic analysis in human fibrosarcoma HT-1080 cells

scientific article published on August 2012

Identification of putative ligand binding sites within I domain of integrin α2β1 (VLA-2,CD49b/CD29)

scientific article published in Journal of Biological Chemistry

Increase in hepatic pyruvate (glyoxylate) aminotransferase activity on administration of clofibrate to the rat

scientific article published on 01 February 1981

Inhibition of tissue factor signaling suppresses tumor growth

scientific article

Insulin-like Growth Factor (IGF) Signaling Requires αvβ3-IGF1-IGF Type 1 Receptor (IGF1R) Ternary Complex Formation in Anchorage Independence, and the Complex Formation Does Not Require IGF1R and Src Activation ⬇️

scientific article published on December 14, 2012

Integrin alpha3beta1 expressed by human colon cancer cells is a major carrier of oncodevelopmental carbohydrate epitopes

scientific article published in February 1999

Integrin-using rotaviruses bind alpha2beta1 integrin alpha2 I domain via VP4 DGE sequence and recognize alphaXbeta2 and alphaVbeta3 by using VP7 during cell entry

scientific article

Integrins αvβ3 and α4β1 Act as Coreceptors for Fractalkine, and the Integrin-Binding Defective Mutant of Fractalkine Is an Antagonist of CX3CR1 ⬇️

scientific article published on November 2, 2012

Intraperoxisomal and Intramitochondrial Localization, and Assay of Pyruvate (Glyoxylate) Aminotransferase from Rat Liver

scientific article published in 1979

Intraperoxisomal and intramitochondrial localization, and assay of pyruvate (glyoxylate) aminotransferase from rat liver

scientific article published on July 1, 1979

Kidney alanine: Glyoxylate aminotransferase isoenzymes; species distribution, subcellular distribution and properties

scientific article published in 1980

Model of the alphaLbeta2 integrin I-domain/ICAM-1 DI interface suggests that subtle changes in loop orientation determine ligand specificity

scientific article published on August 2002

Molecular Basis of Ligand Recognition by Integrin α5β1

scientific article published in Journal of Biological Chemistry

Monkey rotavirus binding to alpha2beta1 integrin requires the alpha2 I domain and is facilitated by the homologous beta1 subunit

scientific article published on September 2003

Multiple discontinuous ligand-mimetic antibody binding sites define a ligand binding pocket in integrin alpha(IIb)beta(3).

scientific article published on March 2000

Multiple loop structures critical for ligand binding of the integrin alpha4 subunit in the upper face of the beta-propeller mode 1

scientific article published on July 1997

Mutational analysis of cell cycle inhibition by integrin beta1C.

scientific article published on March 1999

Non-cytotoxic cobra cardiotoxin A5 binds to alpha(v)beta3 integrin and inhibits bone resorption. Identification of cardiotoxins as non-RGD integrin-binding proteins of the Ly-6 family

scientific article published on 10 January 2006

Novel point mutations in the alphaIIb subunit (Phe289-->Ser, Glu324-->Lys and Gln747-->Pro) causing thrombasthenic phenotypes in four Japanese patients

scientific article published in August 1998

Peroxisomal localization of alanine: Glyoxylate aminotransferase in human liver

scientific article published on 01 September 1979

Plasmin-induced migration of endothelial cells. A potential target for the anti-angiogenic action of angiostatin

scientific article published on 26 June 2002

Plasmin-induced migration requires signaling through protease-activated receptor 1 and integrin alpha(9)beta(1).

scientific article

Potential role of kringle-integrin interaction in plasmin and uPA actions (a hypothesis).

scientific article published on 16 October 2012

Pro-inflammatory secretory phospholipase A2 type IIA binds to integrins alphavbeta3 and alpha4beta1 and induces proliferation of monocytic cells in an integrin-dependent manner

scientific article published on 17 July 2008

Proinflammatory secreted phospholipase A2 type IIA (sPLA-IIA) induces integrin activation through direct binding to a newly identified binding site (site 2) in integrins αvβ3, α4β1, and α5β1.

scientific article

Propolypeptide of von Willebrand factor is a novel ligand for very late antigen-4 integrin

scientific article

Purification, characterization and identification of aromatic 2-oxo acid reductase ⬇️

scientific article published on February 15, 1977

Regulation of conformation and ligand binding function of integrin alpha5beta1 by the beta1 cytoplasmic domain

scientific article published in July 1996

Role of integrin alpha(v)beta3 in the early phase of liver metastasis: PET and IVM analyses.

scientific article published on January 2002

Rotavirus spike protein VP5* binds alpha2beta1 integrin on the cell surface and competes with virus for cell binding and infectivity

scientific article published on May 2006

Rotavirus-neutralizing antibodies inhibit virus binding to integrins alpha 2 beta 1 and alpha 4 beta 1.

scientific article published on 23 February 2007

Rotaviruses interact with alpha4beta7 and alpha4beta1 integrins by binding the same integrin domains as natural ligands

scientific article

Silencing of DLC1 upregulates PAI-1 expression and reduces migration in normal prostate cells

scientific article

Single-chain antibodies for the conformation-specific blockade of activated platelet integrin alphaIIbbeta3 designed by subtractive selection from naive human phage libraries

scientific article

Specific interaction of angiostatin with integrin alpha(v)beta(3) in endothelial cells

scientific article published on 20 August 2001

Specific interaction of the recombinant disintegrin-like domain of MDC-15 (metargidin, ADAM-15) with integrin alphavbeta3

scientific article

Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site

scientific article

Structural basis of integrin-mediated signal transduction

scientific article

Subcellular distribution, and physical and immunological properties of hepathic alanine: Glyoxylate aminotransferase isoenzymes in different mammalian species

article

The COOH-terminal globular domain of fibrinogen gamma chain suppresses angiogenesis and tumor growth

scientific article published in October 2006

The binding of monomeric C-reactive protein (mCRP) to Integrins αvβ3 and α4β1 is related to its pro-inflammatory action

scientific article

The chemokine fractalkine can activate integrins without CX3CR1 through direct binding to a ligand-binding site distinct from the classical RGD-binding site

scientific article

The direct binding of insulin-like growth factor-1 (IGF-1) to integrin alphavbeta3 is involved in IGF-1 signaling

scientific article

The effect of vitamin B6 deficiency on alanine:Glyoxylate aminotransferase isoenzymes in rat liver

scientific article published on 01 February 1984

The evolution of peroxisomal and mitochondrial alanine: glyoxylate aminotransferase 1 in mammalian liver

scientific article published in September 1982

The integrins

scientific article published on January 2007

The role of alpha and beta chains in ligand recognition by beta 7 integrins

scientific article (publication date: 18 August 2000)

The use of one-bead one-compound combinatorial library technology to discover high-affinity αvβ3 integrin and cancer targeting arginine-glycine-aspartic acid ligands with a built-in handle

scientific article

Three Novel Integrin β3 Subunit Missense Mutations (H280P, C560F, and G579S) in Thrombasthenia, Including One (H280P) Prevalent in Japanese Patients

scientific article published in 1998

Urokinase-type plasminogen activator receptor (CD87) is a ligand for integrins and mediates cell-cell interaction.

scientific article

VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site.

scientific article published on February 1990

[35] Aromatic-amino acid-glyoxylate aminotransferase from rat liver

scientific article published on 01 January 1987

alpha4beta1- and alpha6beta1-integrins are functional receptors for midkine, a heparin-binding growth factor

scientific article published on 5 October 2004

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