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List of works by Nicholas Cross

A British Society for Haematology Guideline on the diagnosis and management of chronic myeloid leukaemia

scientific article published on 30 July 2020

A Novel t(1;9)(p36;p24.1) JAK2 Translocation and Review of the Literature

scientific article published on 07 May 2019

A case of myelofibrosis with a t(4;13)(q25;q12): evidence for involvement of a second 13q12 locus in chronic myeloproliferative disorders

scientific article published on 01 June 1999

A certified plasmid reference material for the standardisation of BCR-ABL1 mRNA quantification by real-time quantitative PCR

scientific article

A comparison of the sensitivity of blood and bone marrow for the detection of minimal residual disease in chronic myeloid leukaemia

article

A constitutively active SPTBN1-FLT3 fusion in atypical chronic myeloid leukemia is sensitive to tyrosine kinase inhibitors and immunotherapy

scientific article published on 30 August 2007

A multi-centre phase 2 study of azacitidine in chronic myelomonocytic leukaemia.

scientific article published on 26 February 2014

A new aldolase B variant, N334K, is a common cause of hereditary fructose intolerance in Yugoslavia

scientific article

A novel BCR-ABL fusion gene (e2/1a) in a patient with Philadelphia-positive chronic myelogenous leukaemia and an aggressive clinical course

article

A novel ETV6-PDGFRB fusion transcript missed by standard screening in a patient with an imatinib responsive chronic myeloproliferative disease

scientific article published on 17 May 2007

A novel K509I mutation of KIT identified in familial mastocytosis-in vitro and in vivo responsiveness to imatinib therapy

scientific article published on 22 September 2005

A novel arrangement of sequence elements surrounding the rDNA promoter and its spacer duplications in tsetse species

scientific article published on May 1987

A novel gene, NSD1, is fused to NUP98 in the t(5;11)(q35;p15.5) in de novo childhood acute myeloid leukemia

scientific article published in August 2001

A polymorphism associated with STAT3 expression and response of chronic myeloid leukemia to interferon α.

scientific article

A potent inhibitor of Taq polymerase copurifies with human genomic DNA.

scientific article published on November 1988

A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome

scientific article

ABL-BCR expression does not correlate with deletions on the derivative chromosome 9 or survival in chronic myeloid leukemia

article

APPROPRIATE CONTROLS FOR REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION (RT-PCR)

scientific article published on 01 May 1994

Aberrant DNA methylation profile of chronic and transformed classic Philadelphia-negative myeloproliferative neoplasms.

scientific article published on 28 May 2013

Aberrant transcripts of the FHIT gene are expressed in normal and leukaemic haemopoietic cells ⬇️

scientific article published on September 1, 1998

Aberrations of EZH2 in cancer

scientific article

Absence of CALR Mutations in Idiopathic Erythrocytosis Patients with Low Serum Erythropoietin Levels

scientific article published on 30 May 2018

Accurate detection and quantitation of heteroplasmic mitochondrial point mutations by pyrosequencing

scientific article published in January 2005

Acquired uniparental disomy in myeloproliferative neoplasms

scientific article published on 18 August 2012

Activity of TKI258 against primary cells and cell lines with FGFR1 fusion genes associated with the 8p11 myeloproliferative syndrome.

scientific article published on 13 August 2007

Acute myeloid leukaemia with associated eosinophilia: justification for FIP1L1-PDGFRA screening in cases lacking the CBFB-MYH11 fusion gene

scientific article published on 19 May 2009

Adoptive immunotherapy for relapse of chronic myeloid leukemia after allogeneic bone marrow transplant: equal efficacy of lymphocytes from sibling and matched unrelated donors

scientific article published on 01 May 1998

Age has a profound effect on the incidence and significance of chromosome abnormalities in myeloma

scientific article published on 01 September 2005

Aldolase B mutations in Italian families affected by hereditary fructose intolerance ⬇️

scientific article published on April 1, 1991

Amplification refractory mutation system, a highly sensitive and simple polymerase chain reaction assay, for the detection of JAK2 V617F mutation in chronic myeloproliferative disorders

scientific article published on April 2007

An International MDS/MPN Working Group's perspective and recommendations on molecular pathogenesis, diagnosis and clinical characterization of myelodysplastic/myeloproliferative neoplasms.

scientific article published on September 2015

An atypical myeloproliferative disorder with t(8;13) (p11;q12): a third case

scientific article published on 01 April 1994

An extremely delayed cytogenetic response to interferon-α in a patient with chronic myeloid leukaemia

scientific article published on 01 April 1997

An international consortium proposal of uniform response criteria for myelodysplastic/myeloproliferative neoplasms (MDS/MPN) in adults

scientific article published on 26 January 2015

Analysis of chronic myeloid leukaemia during deep molecular response by genomic PCR: a traffic light stratification model with impact on treatment-free remission

scientific article published on 29 May 2020

Antisense Oligonucleotides Modulating Activation of a Nonsense-Mediated RNA Decay Switch Exon in the ATM Gene.

scientific article published on 22 September 2016

Aplasia after donor lymphocyte infusion (DLI) for CML in relapse after sex-mismatched BMT: recovery of donor-type haemopoiesis predicted by non-isotopic in situ hybridization (ISH)

scientific article published on 01 October 1994

Assignment 1 of ZNF262 to human chromosome band 1p34→p32 by in situ hybridization

scientific article published on 01 January 1999

Assignment of the Steroid Receptor Coactivator-1 (SRC-1) Gene to Human Chromosome Band 2p23

article

Atypical mRNA fusions in PML-RARA positive, RARA-PML negative acute promyelocytic leukemia.

scientific article published in May 2010

BCR-ABL antisense purging in chronic myeloid leukaemia

scientific article published in The Lancet

BCR-ABL-positive progenitors in chronic myeloid leukaemia patients in complete cytogenetic remission after treatment with interferon-α

scientific article published on 01 September 1998

BCR-ABL1-positive CML and BCR-ABL1-negative chronic myeloproliferative disorders: some common and contrasting features

scientific article published in November 2008

Bioinformatic analyses of CALR mutations in myeloproliferative neoplasms support a role in signaling

scientific article published on 12 June 2014

Broad molecular screening of an unclassifiable myeloproliferative disorder reveals an unexpected ETV6/ABL1 fusion transcript

scientific article published on 01 June 2005

CHIC2 deletion, a surrogate for FIP1L1-PDGFRA fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib mesylate therapy

scientific article (publication date: November 2003)

Characterization of a t(10;12)(q24;p13) in a case of CML in transformation

scientific article published on 01 December 1997

Characterization of genomic BCR-ABL breakpoints in chronic myeloid leukaemia by PCR.

scientific article

Characterization of three new imatinib-responsive fusion genes in chronic myeloproliferative disorders generated by disruption of the platelet-derived growth factor receptor beta gene

scientific article published in February 2007

Chronic eosinophilic leukaemia presenting with erythroderma, mild eosinophilia and hyper-IgE: clinical, immunological and cytogenetic features and therapeutic approach. A case report

scientific article published in January 2002

Chronic myeloid leukemia – some topical issues

scientific article published on 10 May 2007

Chronic myeloproliferative disorders: the role of tyrosine kinases in pathogenesis, diagnosis and therapy.

scientific article published on January 2007

Clinical evidence for a graft-versus-tumour effect following allogeneic HSCT for t(8;13) atypical myeloproliferative disorder

article

Clinical variability of patients with the t(6;8)(q27;p12) and FGFR1OP-FGFR1 fusion: two further cases.

scientific article published in January 2004

Clonal diversity in the myeloproliferative neoplasms: independent origins of genetically distinct clones

scientific article published on 16 January 2009

Clonal myelopoiesis in the UK Biobank cohort: ASXL1 mutations are strongly associated with smoking

scientific article published on 10 June 2020

Cloning and characterization of RNF6, a novel RING finger gene mapping to 13q12.

scientific article published in May 1999

Cloning of ZNF237, a novel member of the MYM gene family that maps to human chromosome 13q11-->q12.

scientific article published in January 2000

Combining gene mutation with gene expression data improves outcome prediction in myelodysplastic syndromes

scientific article

Comparison of mutated ABL1 and JAK2 as oncogenes and drug targets in myeloproliferative disorders

scientific article

Comprehensive mutational profiling in advanced systemic mastocytosis

scientific article published on 19 August 2013

Consensus on BCR-ABL1 reporting in chronic myeloid leukaemia in the UK

scientific article published on 20 August 2018

Consistent fusion of MOZ and TIF2 in AML with inv(8)(p11q13).

scientific article published in August 1999

Correlation between the proportion of Philadelphia chromosome-positive metaphase cells and levels ofBCR-ABL mRNA in chronic myeloid leukaemia

article

Cough and hypereosinophilia due to FIP1L1-PDGFRA fusion gene with tyrosine kinase activity

scientific article published in January 2006

Critical role of STAT5 activation in transformation mediated by ZNF198-FGFR1.

scientific article published on 5 December 2003

Cytogenetics of chronic myeloid leukaemia.

scientific article

DNA topoisomerase II in therapy-related acute promyelocytic leukemia.

scientific article published in April 2005

Decrease in JAK2 V617F allele burden is not a prerequisite to clinical response in patients with polycythemia vera

scientific article

Deletion analysis of the p16 tumour suppressor gene in phaeochromocytomas

article

Deletion of chromosome 13 detected by conventional cytogenetics is a critical prognostic factor in myeloma

scientific article published on 06 July 2006

Der(6)t(1;6)(q21-23;p21.3): a specific cytogenetic abnormality in myelofibrosis with myeloid metaplasia.

scientific article published in July 2005

Desirable performance characteristics for BCR-ABL measurement on an international reporting scale to allow consistent interpretation of individual patient response and comparison of response rates between clinical trials.

scientific article published on 6 August 2008

Detection and molecular monitoring of FIP1L1-PDGFRA-positive disease by analysis of patient-specific genomic DNA fusion junctions

scientific article

Detection and quantification of residual disease in chronic myelogenous leukemia.

scientific article

Detection of leukemia-associated mutations in peripheral blood DNA of hematologically normal elderly individuals

scientific article published on 28 January 2015

Development and evaluation of a secondary reference panel for BCR-ABL1 quantification on the International Scale

scientific article published on 25 April 2016

Diagnostic and therapeutic management of eosinophilia-associated chronic myeloproliferative disorders

scientific article published on 01 September 2007

Diagnostic challenges in the work up of hypereosinophilia: pitfalls in bone marrow core biopsy interpretation

scientific article published on 22 January 2016

Disruption and aberrant expression of HMGA2 as a consequence of diverse chromosomal translocations in myeloid malignancies

scientific article

Distinct stem cell myeloproliferative/T lymphoma syndromes induced by ZNF198-FGFR1 and BCR-FGFR1 fusion genes from 8p11 translocations

scientific journal article

Distribution of genomic breakpoints in chronic myeloid leukemia: analysis of 308 patients

scientific article published on 16 April 2013

Dosage analysis of cancer predisposition genes by multiplex ligation-dependent probe amplification

scientific article

Durable responses to imatinib in patients with PDGFRB fusion gene-positive and BCR-ABL-negative chronic myeloproliferative disorders

scientific article

EZH2 mutational status predicts poor survival in myelofibrosis.

scientific article published on 14 September 2011

Early detection of BCR-ABL transcripts by quantitative reverse transcriptase-polymerase chain reaction predicts outcome after allogeneic stem cell transplantation for chronic myeloid leukemia

scientific article published on 01 March 2001

Eosinophilic disorders: molecular pathogenesis, new classification, and modern therapy

scientific article published on January 2006

Establishing optimal quantitative-polymerase chain reaction assays for routine diagnosis and tracking of minimal residual disease in JAK2-V617F-associated myeloproliferative neoplasms: a joint European LeukemiaNet/MPN&MPNr-EuroNet (COST action BM090

scientific article published on 17 July 2013

Establishment and validation of analytical reference panels for the standardization of quantitative BCR-ABL1 measurements on the international scale

scientific article published on 7 March 2013

Evaluation of methods to detect CALR mutations in myeloproliferative neoplasms.

scientific article published on 29 November 2014

Evolutional change of karyotype with t(8;9)(p22;p24) and HLA-DR immunophenotype in relapsed acute myeloid leukemia

scientific article published on 2 July 2008

Exon-centric regulation of ATM expression is population-dependent and amenable to antisense modification by pseudoexon targeting

scientific article

FIP1L1-PDGFRA in chronic eosinophilic leukemia and BCR-ABL1 in chronic myeloid leukemia affect different leukemic cells

scientific article published on 11 January 2007

Favorable outcome of allogeneic hematopoietic cell transplantation for 8p11 myeloproliferative syndrome associated with BCR-FGFR1 gene fusion.

scientific article

Frequent CBL mutations associated with 11q acquired uniparental disomy in myeloproliferative neoplasms

scientific article published on 22 April 2009

Frequent upregulation of MYC in plasma cell leukemia

scientific article published in July 2009

Frontline nilotinib in patients with chronic myeloid leukemia in chronic phase: results from the European ENEST1st study.

scientific article

Fusion of PDGFRB to MPRIP, CPSF6, and GOLGB1 in three patients with eosinophilia-associated myeloproliferative neoplasms

scientific article

Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma

article

Genomic anatomy of the specific reciprocal translocation t(15;17) in acute promyelocytic leukemia

scientific article

Genomics of Myeloproliferative Neoplasms

scientific article published on 13 February 2017

Guideline for the investigation and management of eosinophilia.

scientific article

Guidelines for the measurement of BCR-ABL1 transcripts in chronic myeloid leukaemia

scientific article published on 8 March 2011

Hereditary fructose intolerance

scientific article published on 01 January 1990

IDH2 somatic mutations in chronic myeloid leukemia patients in blast crisis

scientific article published on 21 October 2010

Identification and functional characterization of imatinib-sensitive DTD1-PDGFRB and CCDC88C-PDGFRB fusion genes in eosinophilia-associated myeloid/lymphoid neoplasms

scientific article published in May 2014

Identification of FOXP1 and SNX2 as novel ABL1 fusion partners in acute lymphoblastic leukaemia.

scientific article

Identification of U2AF(35)-dependent exons by RNA-Seq reveals a link between 3' splice-site organization and activity of U2AF-related proteins.

scientific article

Identification of a novel gene, FGFR1OP2, fused to FGFR1 in 8p11 myeloproliferative syndrome

scientific article published in May 2004

Identification of a novel imatinib responsive KIF5B-PDGFRA fusion gene following screening for PDGFRA overexpression in patients with hypereosinophilia

scientific article published in May 2006

Identification of four new translocations involving FGFR1 in myeloid disorders

scientific article

Idiopathic hypereosinophilic syndrome in children: report of a 7-year-old boy with FIP1L1-PDGFRA rearrangement.

scientific article

Imatinib for systemic mast-cell disease

scientific article published in August 2003

Imatinib sensitivity as a consequence of a CSF1R-Y571D mutation and CSF1/CSF1R signaling abnormalities in the cell line GDM1.

scientific article

Imatinib therapy for hypereosinophilic syndrome and other eosinophilic disorders

scientific article

Impact of BCR-ABL mutations on patients with chronic myeloid leukemia.

scientific article published on 15 January 2011

Impact of centralized evaluation of bone marrow histology in systemic mastocytosis.

scientific article

Impact of isolated germline JAK2V617I mutation on human hematopoiesis

scientific article published on 27 March 2013

In search of the original leukemic clone in chronic myeloid leukemia patients in complete molecular remission after stem cell transplantation or imatinib.

scientific article published on 12 May 2010

Inactivation of polycomb repressive complex 2 components in myeloproliferative and myelodysplastic/myeloproliferative neoplasms

scientific article published on 3 November 2011

Inhibitory effects of midostaurin and avapritinib on myeloid progenitors derived from patients with KIT D816V positive advanced systemic mastocytosis

scientific article published on 25 March 2019

Interlaboratory diagnostic validation of conformation-sensitive capillary electrophoresis for mutation scanning

scientific article published on 18 February 2010

International Working Group (IWG) consensus criteria for treatment response in myelofibrosis with myeloid metaplasia, for the IWG for Myelofibrosis Research and Treatment (IWG-MRT).

scientific article

International standardisation of quantitative real-time RT-PCR for BCR-ABL

article

Is cancer latency an outdated concept? Lessons from chronic myeloid leukemia

scientific article published on 06 July 2020

Isolation and characterization of the genes encoding mouse and human type-5 acid phosphatase

scientific journal article

JAK2 Mutations are present in all cases of polycythemia vera

scientific article published on 13 December 2007

JAK2 V617F mutation in classic chronic myeloproliferative diseases: a report on a series of 349 patients

scientific article published on 01 March 2006

JAK2(V617F) allele burden in polycythemia vera correlates with grade of myelofibrosis, but is not substantially affected by therapy

scientific article published on 22 July 2010

JAK2V617F allele burden, JAK2 46/1 haplotype and clinical features of Chinese with myeloproliferative neoplasms

article

JAK2V617F mutational frequency in polycythemia vera: 100%, >90%, less?

scientific article published on 31 August 2006

KIT D816 mutated/CBF-negative acute myeloid leukemia: a poor-risk subtype associated with systemic mastocytosis

scientific article published on 11 January 2019

KIT D816V and JAK2 V617F mutations are seen recurrently in hypereosinophilia of unknown significance

scientific article

KIT mutation analysis in mast cell neoplasms: recommendations of the European Competence Network on Mastocytosis

scientific article

Laboratory recommendations for scoring deep molecular responses following treatment for chronic myeloid leukemia.

scientific article published on 5 February 2015

Limited clinical activity of nilotinib and sorafenib in FIP1L1-PDGFRA positive chronic eosinophilic leukemia with imatinib-resistant T674I mutation

scientific article published on 5 August 2011

Limited duration of complete remission on ruxolitinib in myeloid neoplasms with PCM1-JAK2 and BCR-JAK2 fusion genes

scientific article published on 27 September 2014

Localization of the 8;13 translocation breakpoint associated with myeloproliferative disease to a 1.5 mbp region of chromosome 13

article

Long-term follow-up of treatment with imatinib in eosinophilia-associated myeloid/lymphoid neoplasms with PDGFR rearrangements in blast phase

scientific article published on 25 April 2013

Low expression of the putative tumour suppressor gene gravin in chronic myeloid leukaemia, myelodysplastic syndromes and acute myeloid leukaemia

scientific article

Low frequency mutations independently predict poor treatment-free survival in early stage chronic lymphocytic leukemia and monoclonal B-cell lymphocytosis.

scientific article published on 20 February 2015

Measurement of BCR-ABL1 by RT-qPCR in chronic myeloid leukaemia: findings from an International EQA Programme.

scientific article

Megalencephaly syndromes: exome pipeline strategies for detecting low-level mosaic mutations

scientific article

Methylation-Sensitive High-Resolution Melting-Curve Analysis of the SNRPN Gene as a Diagnostic Screen for Prader-Willi and Angelman Syndromes

article

Minimal Residual Disease after Bone Marrow Transplant for Chronic Myeloid Leukaemia Detected by the Polymerase Chain Reaction

article

Minimal molecular response in polycythemia vera patients treated with imatinib or interferon alpha

scientific article

Minimal residual disease after allogeneic bone marrow transplantation for chronic myeloid leukaemia in first chronic phase: correlations with acute graft-versus-host disease and relapse

scientific article published in May 1993

Modification of British Committee for Standards in Haematology diagnostic criteria for essential thrombocythaemia

scientific article published on 17 June 2014

Molecular analysis of aldolase B genes in hereditary fructose intolerance

scientific article

Molecular basis of myelodysplastic/myeloproliferative neoplasms

scientific article published on December 2009

Molecular diagnosis of the myeloproliferative neoplasms: UK guidelines for the detection of JAK2 V617F and other relevant mutations

scientific article published on 11 October 2012

Molecular pathogenesis of atypical CML, CMML and MDS/MPN-unclassifiable.

scientific article published on 12 September 2014

Molecular profiling of chronic myelomonocytic leukemia reveals diverse mutations in >80% of patients with TET2 and EZH2 being of high prognostic relevance

article

Molecular profiling of myeloid progenitor cells in multi-mutated advanced systemic mastocytosis identifies KIT D816V as a distinct and late event.

scientific article published on 8 January 2015

Molecular response of CML patients treated with interferon-alpha monitored by quantitative Southern blot analysis

article

Molecular studies in patients with chronic myeloid leukaemia in remission 5 years after allogeneic stem cell transplant define the risk of subsequent relapse

article

Mutational mechanisms of EZH2 inactivation in myeloid neoplasms

scientific article published on 22 April 2020

Mutations affecting mRNA splicing define distinct clinical phenotypes and correlate with patient outcome in myelodysplastic syndromes.

scientific article

Mutations and prognosis in primary myelofibrosis

scientific article published on 26 April 2013

Mutations in SETBP1 are recurrent in myelodysplastic syndromes and often coexist with cytogenetic markers associated with disease progression.

scientific article published on 24 July 2013

Mutations of the transcription factor AML1/CBA2 are uncommon in blastic transformation of chronic myeloid leukaemia

scientific article published on 01 March 2001

Myeloproliferative disorders

scientific article published on 01 September 2001

Myeloproliferative disorders with translocations of chromosome 5q31-35: role of the platelet-derived growth factor receptor Beta

scientific article (publication date: 2002)

NIN, a gene encoding a CEP110-like centrosomal protein, is fused to PDGFRB in a patient with a t(5;14)(q33;q24) and an imatinib-responsive myeloproliferative disorder

scientific article

NUP98-LEDGF fusion and t(9;11) in transformed chronic myeloid leukemia

scientific article

Neutrophilic leukemoid reaction in multiple myeloma

scientific article published in November 2015

Nilotinib first-line therapy in patients with Philadelphia chromosome-negative/BCR-ABL-positive chronic myeloid leukemia in chronic phase: ENEST1st sub-analysis

scientific article

No evidence for increased prevalence of JAK2 V617F in women with a history of recurrent miscarriage.

scientific article

Non-random involvement of chromosome 13 in patients with persistent or relapsed disease after bone-marrow transplantation for chronic myeloid leukemia

scientific article published on 01 March 2000

Novel imatinib-sensitive PDGFRA-activating point mutations in hypereosinophilic syndrome induce growth factor independence and leukemia-like disease

scientific article published on 11 January 2011

Novel translocations that disrupt the platelet-derived growth factor receptor beta (PDGFRB) gene in BCR-ABL-negative chronic myeloproliferative disorders.

scientific article published in January 2003

Null alleles of the aldolase B gene in patients with hereditary fructose intolerance

scientific article

Oncogenic derivatives of platelet-derived growth factor receptors.

scientific article

P2X7 polymorphism and chronic lymphocytic leukaemia: lack of correlation with incidence, survival and abnormalities of chromosome 12

scientific article published on 01 November 2003

Patients with myeloid malignancies bearing PDGFRB fusion genes achieve durable long-term remissions with imatinib

scientific article

Persistence of bone marrow micrometastases in patients receiving adjuvant therapy for breast cancer: results at 4 years.

scientific article published in March 2005

Philadelphia chromosome-negative myeloproliferative neoplasm with a novel platelet-derived growth factor receptor-β rearrangement responsive to imatinib.

scientific article published on 13 February 2012

Ponatinib as targeted therapy for FGFR1 fusions associated with the 8p11 myeloproliferative syndrome

scientific article

Profound parental bias associated with chromosome 14 acquired uniparental disomy indicates targeting of an imprinted locus

scientific article

Prognostic score including gene mutations in chronic myelomonocytic leukemia.

scientific article

Quantification of PML-RARalpha transcripts in acute promyelocytic leukaemia: explanation for the lack of sensitivity of RT-PCR for the detection of minimal residual disease and induction of the leukaemia-specific mRNA by alpha interferon

article

Quantification of minimal residual disease in patients with BCR-ABL-positive acute lymphoblastic leukaemia using quantitative competitive polymerase chain reaction

scientific article published on 01 September 1999

Rapid identification of JAK2 exon 12 mutations using high resolution melting analysis

scientific article published on 12 August 2008

Rarity of dominant-negative mutations of the G-CSF receptor in patients with blast crisis of chronic myeloid leukemia or de novo acute leukemia

scientific article published in July 1997

Rarity of microsatellite alterations in acute myeloid leukaemia.

scientific article published on July 1996

Real-world tyrosine kinase inhibitor treatment pathways, monitoring patterns and responses in patients with chronic myeloid leukaemia in the United Kingdom: the UK TARGET CML study

scientific article published on 24 May 2020

Recurrent CEP85L-PDGFRB fusion in patient with t(5;6) and imatinib-responsive myeloproliferative neoplasm with eosinophilia.

scientific article

Recurrent activating STAT5B N642H mutation in myeloid neoplasms with eosinophilia

scientific article published on 20 December 2018

Response to imatinib mesylate in patients with chronic myeloproliferative diseases with rearrangements of the platelet-derived growth factor receptor beta

scientific article published in August 2002

Ruxolitinib as potential targeted therapy for patients with JAK2 rearrangements ⬇️

scientific article published on August 8, 2012

Ruxolitinib, a potent JAK1/JAK2 inhibitor, induces temporary reductions in the allelic burden of concurrent CSF3R mutations in chronic neutrophilic leukemia.

scientific article published on 16 March 2017

Safety and efficacy of imatinib in chronic eosinophilic leukaemia and hypereosinophilic syndrome: a phase-II study

scientific article

Serial measurement of BCR-ABL transcripts in the peripheral blood after allogeneic stem cell transplantation for chronic myeloid leukemia: an attempt to define patients who may not require further therapy

scientific article published on 31 January 2006

Signal transduction therapy in haematological malignancies: identification and targeting of tyrosine kinases

scientific article published on October 2006

Simultaneous MLPA-based multiplex point mutation and deletion analysis of the Dystrophin gene

article

Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2

scientific article

Splenomegaly, elevated alkaline phosphatase and mutations in the SRSF2/ASXL1/RUNX1 gene panel are strong adverse prognostic markers in patients with systemic mastocytosis.

scientific article published on 15 July 2016

Standardisation of molecular monitoring for chronic myeloid leukaemia

scientific article published on September 2009

Standardization of molecular monitoring for chronic myeloid leukemia in Latin America using locally produced secondary cellular calibrators.

scientific article published on 25 July 2016

Standardized definitions of molecular response in chronic myeloid leukemia.

scientific article published on 16 April 2012

TEL-AML1 fusion in acute lymphoblastic leukaemia of adults

article

TFG, a target of chromosome translocations in lymphoma and soft tissue tumors, fuses to GPR128 in healthy individuals

scientific article

The 8p11 myeloproliferative syndrome: a distinct clinical entity caused by constitutive activation of FGFR1

scientific article (publication date: 2002)

The JAK2 46/1 haplotype predisposes to MPL-mutated myeloproliferative neoplasms

scientific article

The KIT D816V expressed allele burden for diagnosis and disease monitoring of systemic mastocytosis.

scientific article

The clinical significance of NOTCH1 and SF3B1 mutations in the UK LRF CLL4 trial.

scientific article

The commonly deleted region at 9p21-22 in lymphoblastic leukemias spans at least 400 kb and includes p16 but not p15 or the IFN gene cluster

article

The effect of initial molecular profile on response to recombinant interferon-α (rIFNα) treatment in early myelofibrosis

scientific article published on 18 May 2017

The future of JAK inhibition in myelofibrosis and beyond

scientific article published on 28 June 2014

The genomic structure of ZNF198 and location of breakpoints in the t(8;13) myeloproliferative syndrome

scientific article

The influence of INK4 proteins on growth and self-renewal kinetics of hematopoietic progenitor cells.

scientific article published on May 2001

The molecular anatomy of the FIP1L1-PDGFRA fusion gene

scientific article published on 6 November 2008

The myeloproliferative neoplasm-associated JAK2 46/1 haplotype is not overrepresented in chronic myelogenous leukemia.

scientific article

The number of prognostically detrimental mutations and prognosis in primary myelofibrosis: an international study of 797 patients

scientific article published on 19 February 2014

The rate and kinetics of molecular response to donor leucocyte transfusions in chronic myeloid leukaemia patients treated for relapse after allogeneic bone marrow transplantation

article

The severity of FIP1L1-PDGFRA-positive chronic eosinophilic leukaemia is associated with polymorphic variation at the IL5RA locus.

scientific article published on 4 October 2007

The t(14;20) is a poor prognostic factor in myeloma but is associated with long-term stable disease in monoclonal gammopathies of undetermined significance

scientific article

The t(1;9)(p34;q34) and t(8;12)(p11;q15) fuse pre-mRNA processing proteins SFPQ (PSF) and CPSF6 to ABL and FGFR1.

scientific article published on May 2008

The t(4;22)(q12;q11) in atypical chronic myeloid leukaemia fuses BCR to PDGFRA.

scientific article published in June 2002

The t(4;9)(q11;q33) fuses CEP110 to KIT in a case of acute myeloid leukemia

scientific article published on 15 March 2011

The t(8;17)(p11;q23) in the 8p11 myeloproliferative syndrome fuses MYO18A to FGFR1.

scientific article

The t(8;22) in chronic myeloid leukemia fuses BCR to FGFR1: transforming activity and specific inhibition of FGFR1 fusion proteins

scientific journal article

Transient response to imatinib in a chronic eosinophilic leukemia associated with ins(9;4)(q33;q12q25) and a CDK5RAP2-PDGFRA fusion gene

scientific article published in October 2006

Two novel imatinib-responsive PDGFRA fusion genes in chronic eosinophilic leukaemia

article

Two patients with novel BCR/ABL fusion transcripts (e8/a2 and e13/a2) resulting from translocation breakpoints within BCR exons

scientific article published on 01 May 1999

Type 5 acid phosphatase. Sequence, expression and chromosomal localization of a differentiation-associated protein of the human macrophage

scientific article

Tyrosine kinase fusion genes in chronic myeloproliferative diseases.

scientific article

Tyrosine kinases as therapeutic targets in BCR-ABL negative chronic myeloproliferative disorders

scientific article published on February 2007

Variable numbers of BCR-ABL transcripts persist in CML patients who achieve complete cytogenetic remission with interferon-α

scientific article published on 01 September 1995

Why do we see JAK2 exon 12 mutations in myeloproliferative neoplasms?

scientific article published on 20 March 2013

Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disorders

scientific article published on 26 May 2005

p53-Binding protein 1 is fused to the platelet-derived growth factor receptor beta in a patient with a t(5;15)(q33;q22) and an imatinib-responsive eosinophilic myeloproliferative disorder

scientific article published in October 2004

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