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List of works by Brendan Harley

A collagen-glycosaminoglycan scaffold supports adult rat mesenchymal stem cell differentiation along osteogenic and chondrogenic routes

scientific article

A computational model of feedback-mediated hematopoietic stem cell differentiation in vitro

scientific article published on 01 March 2019

A gelatin hydrogel to study endometrial angiogenesis and trophoblast invasion

scientific article published on 16 August 2019

A new technique for calculating individual dermal fibroblast contractile forces generated within collagen-GAG scaffolds

scientific article

Anisotropic mineralized collagen scaffolds accelerate osteogenic response in a glycosaminoglycan-dependent fashion

scientific article published on 21 April 2020

Award Winner in the Young Investigator Category, 2014 Society for Biomaterials Annual Meeting and Exposition, Denver, Colorado, April 16-19, 2014: Periodically perforated core-shell collagen biomaterials balance cell infiltration, bioactivity, [...]

scientific article

CXCR4/CXCL12 signaling impacts enamel progenitor cell proliferation and motility in the dental stem cell niche.

scientific article

Challenges and Opportunities to Harnessing the (Hematopoietic) Stem Cell Niche

scientific article published on 29 January 2016

Collagen Scaffolds Incorporating Coincident Gradations of Instructive Structural and Biochemical Cues for Osteotendinous Junction Engineering

scientific article published on 19 January 2015

Collagen scaffold arrays for combinatorial screening of biophysical and biochemical regulators of cell behavior

scientific article

Collagen-GAG scaffold biophysical properties bias MSC lineage choice in the presence of mixed soluble signals.

scientific article published on 25 March 2014

Composite growth factor supplementation strategies to enhance tenocyte bioactivity in aligned collagen-GAG scaffolds.

scientific article published on 4 January 2013

Correction: Nanoscale mechanics guides cellular decision making.

scientific article published in September 2016

Crosstalk between microglia and patient-derived glioblastoma cells inhibit invasion in a three-dimensional gelatin hydrogel model

scientific article published on 18 November 2020

Design of a multiphase osteochondral scaffold III: Fabrication of layered scaffolds with continuous interfaces.

scientific article published in March 2010

Design of a multiphase osteochondral scaffold. I. Control of chemical composition.

scientific article published in March 2010

Design of a multiphase osteochondral scaffold. II. Fabrication of a mineralized collagen-glycosaminoglycan scaffold.

scientific article published in March 2010

Development of an inexpensive Raman-compatible substrate for the construction of a microarray screening platform

scientific article published on 01 October 2020

Engineering the hematopoietic stem cell niche: Frontiers in biomaterial science

scientific article

Enhanced live cell imaging via photonic crystal enhanced fluorescence microscopy.

scientific article

Extracellular Hyaluronic Acid Influences the Efficacy of EGFR Tyrosine Kinase Inhibitors in a Biomaterial Model of Glioblastoma.

scientific article published on 2 August 2017

Heterotypic tumor models through freeform printing into photostabilized granular microgels

scientific article published on 01 June 2021

Hypoxia activates enhanced invasive potential and endogenous hyaluronic acid production by glioblastoma cells.

scientific article published on 27 February 2018

Identifying States along the Hematopoietic Stem Cell Differentiation Hierarchy with Single Cell Specificity via Raman Spectroscopy

scientific article

Identifying differentiation stage of individual primary hematopoietic cells from mouse bone marrow by multivariate analysis of TOF-secondary ion mass spectrometry data

scientific article

Immunomodulatory effects of amniotic membrane matrix incorporated into collagen scaffolds

scientific article published on 22 January 2016

Incorporation of the Amniotic Membrane as an Immunomodulatory Design Element in Collagen Scaffolds for Tendon Repair

scientific article published on 19 October 2018

Increasing the strength and bioactivity of collagen scaffolds using customizable arrays of 3D-printed polymer fibers

scientific article published on 02 February 2016

Marrow-inspired matrix cues rapidly affect early fate decisions of hematopoietic stem and progenitor cells.

scientific article published on 06 January 2017

Microarchitecture of three-dimensional scaffolds influences cell migration behavior via junction interactions

scientific article published on 11 July 2008

Microfluidic generation of gradient hydrogels to modulate hematopoietic stem cell culture environment.

scientific article published on 29 August 2013

Mineralized collagen scaffolds fabricated with amniotic membrane matrix increase osteogenesis under inflammatory conditions

scientific article published on 07 April 2020

Mineralized collagen scaffolds induce hMSC osteogenesis and matrix remodeling

scientific article published on March 2015

Nanoparticulate Mineralized Collagen Scaffolds and BMP-9 Induce a Long-Term Bone Cartilage Construct in Human Mesenchymal Stem Cells

scientific article

Nanoparticulate mineralized collagen scaffolds induce in vivo bone regeneration independent of progenitor cell loading or exogenous growth factor stimulation.

scientific article published on 18 February 2016

Nanoscale mechanics guides cellular decision making

scientific article published on August 2016

Optimizing Collagen Scaffolds for Bone Engineering: Effects of Cross-linking and Mineral Content on Structural Contraction and Osteogenesis

scientific article (publication date: September 2015)

Osteogenesis on nanoparticulate mineralized collagen scaffolds via autogenous activation of the canonical BMP receptor signaling pathway

scientific article

Osteoprotegerin reduces osteoclast resorption activity without affecting osteogenesis on nanoparticulate mineralized collagen scaffolds

scientific article published on 12 June 2019

Patterning Three-Dimensional Hydrogel Microenvironments Using Hyperbranched Polyglycerols for Independent Control of Mesh Size and Stiffness.

scientific article published on 28 February 2017

Perivascular Secretome Influences Hematopoietic Stem Cell Maintenance in a Gelatin Hydrogel

scientific article published on 16 September 2020

Perivascular Stromal Cells Instruct Glioblastoma Invasion, Proliferation, and Therapeutic Response within an Engineered Brain Perivascular Niche Model

scientific article published in 2022

Photonic crystal enhanced microscopy for imaging of live cell adhesion

scientific article published on 22 August 2013

Photopatterning of vascular endothelial growth factor within collagen-glycosaminoglycan scaffolds can induce a spatially confined response in human umbilical vein endothelial cells

scientific article published on 09 July 2014

Planar Photonic Crystal Biosensor for Quantitative Label-Free Cell Attachment Microscopy

scientific article

Proangiogenic Activity of Endometrial Epithelial and Stromal Cells in Response to Estradiol in Gelatin Hydrogels.

scientific article published on 15 August 2017

Quantitative analysis of focal adhesion dynamics using photonic resonator outcoupler microscopy (PROM)

scientific article published on 30 May 2018

Quantitative imaging of haematopoietic stem and progenitor cell localization and hypoxic status in the bone marrow microenvironment

scientific article

Relationship between permeability and diffusivity in polyethylene glycol hydrogels

scientific article published on 04 October 2018

Response of neuroglia to hypoxia-induced oxidative stress using enzymatically crosslinked hydrogels

scientific article published on 18 December 2019

Rheological Analysis of the Gelation Kinetics of an Enzyme Cross-linked PEG Hydrogel

scientific article published on 10 May 2019

SOCS3 protein developmentally regulates the chemokine receptor CXCR4-FAK signaling pathway during B lymphopoiesis.

scientific article published in November 2007

Sequential sequestrations increase the incorporation and retention of multiple growth factors in mineralized collagen scaffolds

scientific article published on 20 July 2020

Soluble Signals and Remodeling in a Synthetic Gelatin-Based Hematopoietic Stem Cell Niche

scientific article published on 18 September 2019

Spatially gradated hydrogel platform as a 3D engineered tumor microenvironment.

scientific article published on 17 December 2014

Spatially graded hydrogels for preclinical testing of glioblastoma anticancer therapeutics.

scientific article published on 12 September 2017

Strategies to balance covalent and non-covalent biomolecule attachment within collagen-GAG biomaterials

scientific article

Structural and biochemical modification of a collagen scaffold to selectively enhance MSC tenogenic, chondrogenic, and osteogenic differentiation

scientific article

The Effect of Gradations in Mineral Content, Matrix Alignment, and Applied Strain on Human Mesenchymal Stem Cell Morphology within Collagen Biomaterials.

scientific article published on June 2016

The Influence of Hyaluronic Acid and Glioblastoma Cell Coculture on the Formation of Endothelial Cell Networks in Gelatin Hydrogels

scientific article

The combined effects of matrix stiffness and growth factor immobilization on the bioactivity and differentiation capabilities of adipose-derived stem cells

scientific article

The combined influence of substrate elasticity and ligand density on the viability and biophysical properties of hematopoietic stem and progenitor cells

scientific article published on 22 March 2012

The effect of glycosaminoglycan content on polyethylenimine-based gene delivery within three-dimensional collagen-GAG scaffolds

scientific article published on April 2015

The generation of biomolecular patterns in highly porous collagen-GAG scaffolds using direct photolithography

scientific article published on June 2011

The induction of pro-angiogenic processes within a collagen scaffold via exogenous estradiol and endometrial epithelial cells

scientific article

The influence of collagen-glycosaminoglycan scaffold relative density and microstructural anisotropy on tenocyte bioactivity and transcriptomic stability.

scientific article published on 24 December 2011

The influence of pore size and stiffness on tenocyte bioactivity and transcriptomic stability in collagen-GAG scaffolds

scientific article published on 29 August 2016

The use of bioinspired alterations in the glycosaminoglycan content of collagen-GAG scaffolds to regulate cell activity

scientific article

The use of covalently immobilized stem cell factor to selectively affect hematopoietic stem cell activity within a gelatin hydrogel

scientific article

Three-dimensional tissue cytometer based on high-speed multiphoton microscopy

scientific article published on December 2007

Tough and tunable scaffold-hydrogel composite biomaterial for soft-to-hard musculoskeletal tissue interfaces

scientific article published on 19 August 2020

Tracing Hematopoietic Progenitor Cell Neutrophilic Differentiation via Raman Spectroscopy

scientific article published on 06 September 2018

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