Search filters

List of works by Pieter Wesseling

3'-Deoxy-3'-18F-fluorothymidine PET-derived proliferative volume predicts overall survival in high-grade glioma patients.

scientific article published on 17 October 2012

<scp>AllergoOncology</scp>: Biomarkers and refined classification for research in the allergy and glioma nexus—A joint <scp>EAACI‐EANO</scp> position paper

scientific article published in 2024

A clinicopathologic study of 11 rosette-forming meningiomas: a rare and potentially confusing pattern

scientific article published on 24 June 2015

A hypermethylated phenotype is a better predictor of survival than MGMT methylation in anaplastic oligodendroglial brain tumors: a report from EORTC study 26951.

scientific article

A new technique for the assessment of the draining area of a cerebral vein

scientific article

A novel seven-octapeptide repeat insertion in the prion protein gene (PRNP) in a Dutch pedigree with Gerstmann-Sträussler-Scheinker disease phenotype: comparison with similar cases from the literature

scientific article

A pilot study on slit lamp-adapted optical coherence tomography imaging of trabeculectomy filtering blebs.

scientific article published on 22 November 2006

A spinal intradural enterogenous cyst with well-differentiated muscularis propria.

scientific article published in August 2002

A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR

scientific article published on 01 November 2020

A uniform histological cluster scheme for ICD-O-coded primary central nervous system tumors.

scientific article

Accumulation of heparan sulfate proteoglycans in cerebellar senile plaques

scientific article published in July 2002

Accurate classification of childhood brain tumours by in vivo ¹H MRS - a multi-centre study

scientific article published on 2 October 2012

Activating mutations of the GNAQ gene: a frequent event in primary melanocytic neoplasms of the central nervous system

scientific article

Agrin is a major heparan sulfate proteoglycan accumulating in Alzheimer's disease brain.

scientific article published on December 1999

Alpha-internexin expression predicts outcome in anaplastic oligodendroglial tumors and may positively impact the efficacy of chemotherapy: European organization for research and treatment of cancer trial 26951.

scientific article published on 18 January 2011

Aminopeptidase A is a functional target in angiogenic blood vessels

scientific article

Amyloid-beta-induced degeneration of human brain pericytes is dependent on the apolipoprotein E genotype

scientific article published in April 2000

Analysis of von Hippel—Lindau mutations with comparative genomic hybridization in sporadic and hereditary hemangioblastomas: possible genetic heterogeneity

scientific article published on 01 October 2002

Announcing cIMPACT-NOW: the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy

scientific article

Antiangiogenic therapy of cerebral melanoma metastases results in sustained tumor progression via vessel co-option

scientific article published on September 2004

CD4+FoxP3+ regulatory T cells gradually accumulate in gliomas during tumor growth and efficiently suppress antiglioma immune responses in vivo

scientific article published in July 2007

Can excision of meningiomas be limited to resection of tumor and radiologically abnormal dura mater? Neuronavigation-guided biopsies of dural tail and seemingly normal dura mater, with a review of the literature

scientific article published on 5 July 2014

Cerebral Amyloid Angiopathy with Severe Secondary Vascular Pathology: A Histopathological Study

scientific article published on 22 September 2005

Characteristic chromosomal aberrations in sporadic cerebellar hemangioblastomas revealed by comparative genomic hybridization

scientific article published in May 2001

Chloroquine combined with concurrent radiotherapy and temozolomide for newly diagnosed glioblastoma: a phase IB trial

scientific article published on 20 September 2020

Choroid plexus carcinoma: a report of two cases and review of the literature.

scientific article published on June 1996

Chromosomal imbalances in primary oligodendroglial tumors and their recurrences: clues about malignant progression detected using comparative genomic hybridization

scientific article published in March 2002

Citrullination of central nervous system proteins during the development of experimental autoimmune encephalomyelitis

scientific article published in June 2005

Clear cell meningiomas are defined by a highly distinct DNA methylation profile and mutations in SMARCE1

scientific article published on 14 December 2020

Clinical value of chromosome arms 19q and 11p losses in low-grade gliomas

scientific article published on 12 December 2013

Comparative genomic hybridization: practical guidelines

scientific article

Comparison between neuroimaging classifications and histopathological diagnoses using an international multicenter brain tumor magnetic resonance imaging database.

scientific article published on July 2006

Computer-assisted analysis of the microvasculature in untreated glioblastomas

scientific article published on 01 January 1995

Contribution of CSF cytology in the diagnostic work-up of breast cancer patients with neurological symptoms: a retrospective analysis over two decades

scientific article published on 4 January 2012

Conventional radiotherapy combined with carbogen breathing and nicotinamide for malignant gliomas.

scientific article published in May 1995

Copy number variation analysis and methylome profiling of a GNAQ-mutant primary meningeal melanocytic tumor and its liver metastasis.

scientific article published on 11 December 2016

Copy number variations as potential diagnostic and prognostic markers for CNS melanocytic neoplasms in neurocutaneous melanosis

scientific article published on 17 December 2016

Correlation between localization, age, and chromosomal imbalances in ependymal tumours as detected by CGH.

scientific article published in June 2002

Cyclin D1 genotype and expression in sporadic hemangioblastomas

scientific article published in September 2005

DNA copy number analysis of fresh and formalin-fixed specimens by shallow whole-genome sequencing with identification and exclusion of problematic regions in the genome assembly

scientific article

DNA methylation-based classification of central nervous system tumours

scientific article published on 14 March 2018

Development and developmental disorders of the human cerebellum ⬇️

scientific article published on September 1, 2003

Development of a decision support system for diagnosis and grading of brain tumours using in vivo magnetic resonance single voxel spectra.

scientific article published in June 2006

Development of the tumor vascular bed in response to hypoxia-induced VEGF-A differs from that in tumors with constitutive VEGF-A expression

scientific article published in November 2006

Diagnostic Accuracy of Neuroimaging to Delineate Diffuse Gliomas within the Brain: A Meta-Analysis

scientific article published on 7 September 2017

Differential effects of vascular endothelial growth factor A isoforms in a mouse brain metastasis model of human melanoma ⬇️

scientific article published on September 1, 2003

Differential patterns of insulin-like growth factor-I and -II mRNA expression in medulloblastoma

scientific article published on 01 October 2004

Diffuse glioma growth: a guerilla war

scientific article published on 06 September 2007

Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.

scientific article published on 25 June 2015

Direct comparison of [11C] choline and [18F] FET PET to detect glioma infiltration: a diagnostic accuracy study in eight patients

scientific article published on 28 June 2019

Discordance in ERα, PR and HER2 receptor status across different distant breast cancer metastases within the same patient

scientific article published on 10 October 2013

EMBR-15. DIAGNOSTIC RE-EVALUATION AND POOLED CLINICAL DATA ANALYSIS OF PATIENTS WITH PREVIOUS DIAGNOSIS OF CNS-PNET

Effects of dual targeting of tumor cells and stroma in human glioblastoma xenografts with a tyrosine kinase inhibitor against c-MET and VEGFR2

scientific article

Effects of targeting the VEGF and PDGF pathways in diffuse orthotopic glioma models.

scientific article

Embryonal tumor with multilayered rosettes (ETMR): signed, sealed, delivered ….

scientific article published in August 2014

Evolution of DNA repair defects during malignant progression of low-grade gliomas after temozolomide treatment

scientific article published on 28 February 2015

Experimental treatment of NRAS-mutated neurocutaneous melanocytosis with MEK162, a MEK-inhibitor

scientific article

Expression pattern of apoptosis-related markers in Huntington's disease

scientific article published on 25 January 2005

Expression profiling of immune inhibitory Siglecs and their ligands in patients with glioma.

scientific article published on 5 April 2019

Fatal thrombotic microangiopathy after a single dose of gemcitabine as fourth-line palliative treatment for metastasized ductal breast carcinoma

scientific article published on 30 August 2010

Genetic reflection of glioblastoma biopsy material in xenografts: characterization of 11 glioblastoma xenograft lines by comparative genomic hybridization

article

Genetics and pharmacogenomics of diffuse gliomas

scientific article published on 14 September 2012

Germline mutation of INI1/SMARCB1 in familial schwannomatosis

scientific article

Giant cavernous hemangiomas: report of three cases

scientific article published on 19 September 2006

Gliomatosis cerebri: quantitative proof of vessel recruitment by cooptation instead of angiogenesis

scientific article published in October 2005

Glutamate as chemotactic fuel for diffuse glioma cells: are they glutamate suckers?

scientific article

Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8.

scientific article

Grading of meningeal solitary fibrous tumors/hemangiopericytomas: analysis of the prognostic value of the Marseille Grading System in a cohort of 132 patients

scientific article published on 07 May 2018

Heparan sulphate proteoglycans in Alzheimer's disease and amyloid-related disorders

scientific article

Histological effects of fibrin glue on nervous tissue: a safety study in rats

scientific article

Human pontine glioma cells can induce murine tumors

scientific article

Hypoxia in a human intracerebral glioma model

scientific article published in September 2000

IDH mutant diffuse and anaplastic astrocytomas have similar age at presentation and little difference in survival: a grading problem for WHO.

scientific article published on 12 May 2015

IDH mutation status and role of WHO grade and mitotic index in overall survival in grade II-III diffuse gliomas

scientific article

Identification of a novel MET mutation in high-grade glioma resulting in an auto-active intracellular protein

scientific article published on 11 April 2015

Identification of subgroups of high-grade oligodendroglial tumors by comparative genomic hybridization.

scientific article published in June 1999

Identification of temozolomide resistance factors in glioblastoma via integrative miRNA/mRNA regulatory network analysis

scientific article

Ileus in mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes ⬇️

scientific article published on July 1, 1998

Implementation of a multi-institutional diffuse intrinsic pontine glioma autopsy protocol and characterization of a primary cell culture

scientific article

Improved discrimination of melanotic schwannoma from melanocytic lesions by combined morphological and GNAQ mutational analysis.

scientific article

In vitro drug response and efflux transporters associated with drug resistance in pediatric high grade glioma and diffuse intrinsic pontine glioma

scientific article

Increase in both CD14-positive and CD15-positive myeloid-derived suppressor cell subpopulations in the blood of patients with glioma but predominance of CD15-positive myeloid-derived suppressor cells in glioma tissue

scientific article published on May 2015

Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG.

scientific article published on 29 May 2013

Intestinal mucosa on top of a rudimentary occipital meningocele in amniotic rupture sequence: disorganization-like syndrome, homeotic transformation, abnormal surface encounter or endoectodermal adhesion?

scientific article published on 01 January 2002

Intramedullary enterogenous cyst presenting with spastic paraparesis during two consecutive pregnancies: a case report.

scientific article published on October 2001

Intrinsic molecular subtypes of glioma are prognostic and predict benefit from adjuvant procarbazine, lomustine, and vincristine chemotherapy in combination with other prognostic factors in anaplastic oligodendroglial brain tumors: a report from EOR

scientific article

Inverse correlation between genetic aberrations and malignancy grade in ependymal tumors: a paradox?

scientific article published in January 2004

Keratitis caused by Scedosporium apiospermum successfully treated with a cornea transplant and voriconazole

scientific article

Landscape of chromosomal copy number aberrations in gangliogliomas and dysembryoplastic neuroepithelial tumours

scientific article published on 12 March 2015

Liquid biopsies in patients with diffuse glioma

scientific article published on 27 February 2015

Long-term wellbeing and neurocognitive functioning of diffuse low-grade glioma patients and their caregivers: A longitudinal study spanning two decades

scientific article published in 2022

Mapping of the SCA23 locus involved in autosomal dominant cerebellar ataxia to chromosome region 20p13-12.3.

scientific article published on 11 August 2004

Massive reduction of tumour load and normalisation of hyperprolactinaemia after high dose cabergoline in metastasised prolactinoma causing thoracic syringomyelia

scientific article

Mechanisms of intimate and long-distance cross-talk between glioma and myeloid cells: how to break a vicious cycle.

scientific article

Meningioma of the pituitary stalk without dural attachment: case report and review of the literature

scientific article published in December 1999

Micronodular transformation as a novel mechanism of VEGF-A-induced metastasis

scientific article published on 12 March 2007

Molecular Analysis as a Tool in the Differential Diagnosis of VHL Disease-Related Tumors

scientific article published on 01 June 2005

Molecular classification of anaplastic oligodendroglioma using next-generation sequencing: a report of the prospective randomized EORTC Brain Tumor Group 26951 phase III trial.

scientific article published on 9 September 2015

Molecular pathogenesis of oligodendroglial tumors

scientific article

Multiplex ligation-dependent probe amplification: a diagnostic tool for simultaneous identification of different genetic markers in glial tumors

scientific article

Multivoxel ¹H MR spectroscopy is superior to contrast-enhanced MRI for response assessment after anti-angiogenic treatment of orthotopic human glioma xenografts and provides handles for metabolic targeting

scientific article published on 24 October 2013

Mutations in g protein encoding genes and chromosomal alterations in primary leptomeningeal melanocytic neoplasms.

scientific article

Myc-associated zinc finger protein (MAZ) is regulated by miR-125b and mediates VEGF-induced angiogenesis in glioblastoma

scientific article published on 13 March 2012

Neuromyelitis optica with clinical and histopathological involvement of the brain

scientific article

Neuropathological diagnostic accuracy

scientific article published in October 2002

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

scientific article

Occurrence of ocular melanoma thirteen years after skin melanoma: two separate primaries or metastatic disease? A case solved with NRAS and CDKN2A (INK4A-ARF) mutational analysis

scientific article published on 01 March 2008

Oligodendroglioma: pathology, molecular mechanisms and markers

scientific article

Overcoming the blood-brain tumor barrier for effective glioblastoma treatment

scientific article published on 06 March 2015

Papillary Tumor of the Pineal Region: A Distinct Molecular Entity

scientific article

Phenotypic and genotypic characterization of orthotopic human glioma models and its relevance for the study of anti-glioma therapy.

scientific article

Pheochromocytoma and gastrointestinal stromal tumors in patients with neurofibromatosis type I.

scientific article published on February 2013

Pituitary apoplexy after mild head injury misinterpreted as bacterial meningitis

scientific article published in July 2007

Premature termination of SMARCB1 translation may be followed by reinitiation in schwannomatosis-associated schwannomas, but results in absence of SMARCB1 expression in rhabdoid tumors.

scientific article published on 17 April 2014

Presence of an oligodendroglioma-like component in newly diagnosed glioblastoma identifies a pathogenetically heterogeneous subgroup and lacks prognostic value: central pathology review of the EORTC_26981/NCIC_CE.3 trial

scientific article published on 15 January 2012

Primary intracranial germ-cell tumors in adults: a practical review.

scientific article

Primary melanocytic tumors of the central nervous system: a review with focus on molecular aspects

scientific article published on March 2015

Primary melanoma of the CNS in children is driven by congenital expression of oncogenic NRAS in melanocytes.

scientific article published on 09 January 2013

Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis

scientific article published on 20 November 2020

Prognostic significance of NAB2-STAT6 fusion variants and TERT promotor mutations in solitary fibrous tumors/hemangiopericytomas of the CNS: not (yet) clear

scientific article published on 02 February 2019

Quantitative analysis of microvascular changes in diffuse astrocytic neoplasms with increasing grade of malignancy

scientific article published in April 1998

Quantitative immunohistological analysis of the microvasculature in untreated human glioblastoma multiforme

scientific article published on 01 December 1994

Quantitative short echo time 1H MRSI of the peripheral edematous region of human brain tumors in the differentiation between glioblastoma, metastasis, and meningioma.

scientific article

RAS/RAF pathway activation in gliomas: the result of copy number gains rather than activating mutations

scientific article published on 23 June 2007

RNA-Seq of Tumor-Educated Platelets Enables Blood-Based Pan-Cancer, Multiclass, and Molecular Pathway Cancer Diagnostics

scientific article

Re: a Word of Caution on New and Revolutionary Diagnostic Tests

scientific article published on 01 February 2016

Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors

scientific article published on 05 August 2021

Retroclival extradural hematoma is a magnetic resonance imaging diagnosis

scientific article published in November 2001

Rosette-forming glioneuronal tumors share a distinct DNA methylation profile and mutations in FGFR1, with recurrent co-mutation of PIK3CA and NF1

scientific article published on 27 June 2019

SF3B1 and EIF1AX mutations occur in primary leptomeningeal melanocytic neoplasms; yet another similarity to uveal melanomas

scientific article

SMARCB1 involvement in the development of leiomyoma in a patient with schwannomatosis

scientific article published in March 2014

Sarcoma classification by DNA methylation profiling

scientific article published on 21 January 2021

Scheie Syndrome Presenting as Myopathy

scientific article published on 01 April 2001

Secondary meningioma in a long-term survivor of atypical teratoid/rhabdoid tumour with a germline INI1 mutation

scientific article published on 31 January 2008

Selective cancer-germline gene expression in pediatric brain tumors

scientific article published on 9 April 2008

Significance of complete 1p/19q co-deletion, IDH1 mutation and MGMT promoter methylation in gliomas: use with caution.

scientific article published on 22 February 2013

Spatial and temporal evolution of distal 10q deletion, a prognostically unfavorable event in diffuse low-grade gliomas

scientific article

Specific association of small heat shock proteins with the pathological hallmarks of Alzheimer's disease brains

scientific article published in April 2006

Spinal xanthomatosis: a variant of cerebrotendinous xanthomatosis

scientific article

Subtyping of oligo-astrocytic tumours by comparative genomic hybridization.

scientific article published in May 2001

Subventricular spread of diffuse intrinsic pontine glioma

scientific article

Successful treatment of Fusarium keratitis with cornea transplantation and topical and systemic voriconazole.

scientific article published on 12 May 2005

Suramin treatment of human glioma xenografts; effects on tumor vasculature and oxygenation status

scientific article published in September 1999

TBIO-17. IMPLEMENTATION OF METHYLATION PROFILING FOR CNS TUMOR DIAGNOSIS IN THE PRINCESS MÁXIMA CENTER FOR PEDIATRIC ONCOLOGY, THE NETHERLANDS

Taxonomy of CNS Tumours; A Series of Three Short Reviews on the WHO 2016 Classification and Beyond.

scientific article

Technical feasibility of integrating 7 T anatomical MRI in image-guided radiotherapy of glioblastoma: a preparatory study.

scientific article published on 30 March 2016

The Aircardi-Goutières syndrome: variable clinical expression in two siblings

scientific article published in May 1997

The cochlear nuclei in two patients with Usher syndrome type I

scientific article published on 01 November 1999

The combination of IDH1 mutations and MGMT methylation status predicts survival in glioblastoma better than either IDH1 or MGMT alone.

scientific article

The immunosuppressive tumour network: myeloid-derived suppressor cells, regulatory T cells and natural killer T cells

scientific article

The molecular landscape of ETMR at diagnosis and relapse

scientific article published on 04 December 2019

The relationship between genetic aberrations as detected by comparative genomic hybridization and vascularization in glioblastoma xenografts

scientific article published in January 2001

Three-dimensional (3D) reconstruction and quantitative analysis of the microvasculature in medulloblastoma and ependymoma subtypes.

scientific article published on 16 November 2006

Towards an integrated morphological and molecular WHO diagnosis of central nervous system tumors: a paradigm shift.

scientific article published on 19 September 2015

Transalar sphenoidal encephalocele and respiratory distress in a neonate: a case report

scientific article published in January 1999

Type 1 papillary renal cell carcinoma in a patient with schwannomatosis: Mosaic versus loss of SMARCB1 expression in respectively schwannoma and renal tumor cells

scientific article published on 22 January 2016

Unique Presentation of Corneal Opacity in Peters Plus Syndrome

scientific article published on 01 February 2016

Upregulation of Claudin-4, CAIX and GLUT-1 in distant breast cancer metastases

scientific article

Vascular density in melanoma xenografts correlates with vascular permeability factor expression but not with metastatic potential.

scientific article published on January 1997

Vascular endothelial growth factor-A determines detectability of experimental melanoma brain metastasis in GD-DTPA-enhanced MRI.

scientific article published in July 2003

Vascular endothelial growth factor-A(165) induces progression of melanoma brain metastases without induction of sprouting angiogenesis

scientific article published on January 2002

Virilization due to ovarian androgen hypersecretion in a patient with ectopic adrenocorticotrophic hormone secretion caused by a carcinoid tumour: Case Report

scientific article published on 13 June 2006

WHO 2016 Classification of gliomas

scientific article published on 16 August 2017

Whole-genome copy-number analysis identifies new leads for chromosomal aberrations involved in the oncogenesis and metastastic behavior of uveal melanomas

scientific article published on June 2015

cIMPACT-NOW (the consortium to inform molecular and practical approaches to CNS tumor taxonomy): a new initiative in advancing nervous system tumor classification

scientific article published on 20 December 2016

Paulina is supported by:

About Paulina

Help