List of works - Craig Powell

A molecular mechanism for ibuprofen-mediated RhoA inhibition in neurons

scientific article

A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice

scientific article

A neuroligin-4 missense mutation associated with autism impairs neuroligin-4 folding and endoplasmic reticulum export

scientific article

Altered Striatal Synaptic Function and Abnormal Behaviour in Shank3 Exon4-9 Deletion Mouse Model of Autism

scientific article

Apparent Genetic Rescue of Adult Shank3 Exon 21 Insertion Mutation Mice Tempered by Appropriate Control Experiments

scientific article published on 27 September 2019

Autism Screening or Smoke Screen and Mirrors?

scientific article published on 16 February 2016

Autism-Associated Insertion Mutation (InsG) of Shank3 Exon 21 Causes Impaired Synaptic Transmission and Behavioral Deficits

scientific article

Autism-related neuroligin-3 mutation alters social behavior and spatial learning

scientific article

Autonomously active protein kinase C in the maintenance phase of N-methyl-D-aspartate receptor-independent long term potentiation.

scientific article

Block of glucocorticoid synthesis during re-activation inhibits extinction of an established fear memory

scientific article

Ca(2+)-induced persistent protein kinase C activation in rat hippocampal homogenates

scientific article published in January 1992

Chronic P7C3 treatment restores hippocampal neurogenesis in the Ts65Dn mouse model of Down Syndrome [Corrected].

scientific article

Clustering autism: using neuroanatomical differences in 26 mouse models to gain insight into the heterogeneity

scientific article published on 9 September 2014

Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation

scientific journal article

Delayed reduction of hippocampal synaptic transmission and spines following exposure to repeated subclinical doses of organophosphorus pesticide in adult mice.

scientific article published on 26 September 2011

Developmental and adult GAP-43 deficiency in mice dynamically alters hippocampal neurogenesis and mossy fiber volume

scientific article

Disparate diseases due to copycat copy number variations.

scientific article published on September 2009

Early restoration of Shank3 expression in Shank3 knockout mice prevents core ASD-like behavioural phenotypes

scientific article published on 17 April 2020

Effects of exogenous glucocorticoid on combat-related PTSD symptoms

scientific article

Efficacy and safety of CP-945,598, a selective cannabinoid CB1 receptor antagonist, on weight loss and maintenance

scientific article published on 3 February 2011

Essential role of brain-derived neurotrophic factor in adult hippocampal function

scientific article

Foxp1 in Forebrain Pyramidal Neurons Controls Gene Expression Required for Spatial Learning and Synaptic Plasticity.

scientific article

Functional and mechanistic exploration of an adult neurogenesis-promoting small molecule.

scientific article

Gene targeting of presynaptic proteins in synaptic plasticity and memory: across the great divide

scientific article

Genetic background effects in Neuroligin-3 mutant mice: Minimal behavioral abnormalities on C57 background

scientific article

Increased Cortical Inhibition in Autism-Linked Neuroligin-3R451C Mice Is Due in Part to Loss of Endocannabinoid Signaling

scientific article published on 15 October 2015

Increased anxiety-like behavior in mice lacking the inhibitory synapse cell adhesion molecule neuroligin 2

scientific article

Loss of predominant Shank3 isoforms results in hippocampus-dependent impairments in behavior and synaptic transmission

scientific article

Lowering beta-amyloid levels rescues learning and memory in a Down syndrome mouse model

scientific article

Motor coordination deficits in mice lacking RGS9

scientific article

Mouse neurexin-1alpha deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments

scientific article

Neuroligin 1 modulates striatal glutamatergic neurotransmission in a pathway and NMDAR subunit-specific manner

scientific article published on 29 July 2015

Neuroligin-1 deletion results in impaired spatial memory and increased repetitive behavior

scientific article

Novel Shank3 mutant exhibits behaviors with face validity for autism and altered striatal and hippocampal function

scientific article published on 5 August 2016

PTEN knockdown alters dendritic spine/protrusion morphology, not density

scientific article

Pearls and oy-sters: acute ischemic stroke caused by atypical thrombotic thrombocytopenic purpura

scientific article

Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice

scientific article

Postreactivation glucocorticoids impair recall of established fear memory.

scientific article

Psychometric Study of the Social Responsiveness Scale in Phelan-McDermid Syndrome

scientific article published on 14 May 2020

Pten regulates neuronal arborization and social interaction in mice

scientific article

RIM1alpha and interacting proteins involved in presynaptic plasticity mediate prepulse inhibition and additional behaviors linked to schizophrenia

scientific article

RIM1alpha phosphorylation at serine-413 by protein kinase A is not required for presynaptic long-term plasticity or learning

scientific article

Region-specific deletions of RIM1 reproduce a subset of global RIM1α(-/-) phenotypes

scientific article

Regulation of hippocampal and behavioral excitability by cyclin-dependent kinase 5.

scientific article

Schizophrenia-relevant behavioral testing in rodent models: a uniquely human disorder?

scientific article published on June 2006

Studies with synthetic peptide substrates derived from the neuronal protein neurogranin reveal structural determinants of potency and selectivity for protein kinase C

scientific article published on 01 February 1993

Temporally specified genetic ablation of neurogenesis impairs cognitive recovery after traumatic brain injury

scientific article published on March 2011

The presynaptic active zone protein RIM1alpha is critical for normal learning and memory

scientific article

List of works by Craig Powell

A molecular mechanism for ibuprofen-mediated RhoA inhibition in neurons

A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice

A neuroligin-4 missense mutation associated with autism impairs neuroligin-4 folding and endoplasmic reticulum export

Altered Striatal Synaptic Function and Abnormal Behaviour in Shank3 Exon4-9 Deletion Mouse Model of Autism

Apparent Genetic Rescue of Adult Shank3 Exon 21 Insertion Mutation Mice Tempered by Appropriate Control Experiments

Autism Screening or Smoke Screen and Mirrors?

Autism-Associated Insertion Mutation (InsG) of Shank3 Exon 21 Causes Impaired Synaptic Transmission and Behavioral Deficits

Autism-related neuroligin-3 mutation alters social behavior and spatial learning

Autonomously active protein kinase C in the maintenance phase of N-methyl-D-aspartate receptor-independent long term potentiation.

Block of glucocorticoid synthesis during re-activation inhibits extinction of an established fear memory

Ca(2+)-induced persistent protein kinase C activation in rat hippocampal homogenates

Chronic P7C3 treatment restores hippocampal neurogenesis in the Ts65Dn mouse model of Down Syndrome [Corrected].

Clustering autism: using neuroanatomical differences in 26 mouse models to gain insight into the heterogeneity

Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation

Delayed reduction of hippocampal synaptic transmission and spines following exposure to repeated subclinical doses of organophosphorus pesticide in adult mice.

Developmental and adult GAP-43 deficiency in mice dynamically alters hippocampal neurogenesis and mossy fiber volume

Disparate diseases due to copycat copy number variations.

Early restoration of Shank3 expression in Shank3 knockout mice prevents core ASD-like behavioural phenotypes

Effects of exogenous glucocorticoid on combat-related PTSD symptoms

Efficacy and safety of CP-945,598, a selective cannabinoid CB1 receptor antagonist, on weight loss and maintenance

Essential role of brain-derived neurotrophic factor in adult hippocampal function

Foxp1 in Forebrain Pyramidal Neurons Controls Gene Expression Required for Spatial Learning and Synaptic Plasticity.

Functional and mechanistic exploration of an adult neurogenesis-promoting small molecule.

Gene targeting of presynaptic proteins in synaptic plasticity and memory: across the great divide

Genetic background effects in Neuroligin-3 mutant mice: Minimal behavioral abnormalities on C57 background

Increased Cortical Inhibition in Autism-Linked Neuroligin-3R451C Mice Is Due in Part to Loss of Endocannabinoid Signaling

Increased anxiety-like behavior in mice lacking the inhibitory synapse cell adhesion molecule neuroligin 2

Loss of predominant Shank3 isoforms results in hippocampus-dependent impairments in behavior and synaptic transmission

Lowering beta-amyloid levels rescues learning and memory in a Down syndrome mouse model

Motor coordination deficits in mice lacking RGS9

Mouse neurexin-1alpha deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments

Neuroligin 1 modulates striatal glutamatergic neurotransmission in a pathway and NMDAR subunit-specific manner

Neuroligin-1 deletion results in impaired spatial memory and increased repetitive behavior

Novel Shank3 mutant exhibits behaviors with face validity for autism and altered striatal and hippocampal function

PTEN knockdown alters dendritic spine/protrusion morphology, not density

Pearls and oy-sters: acute ischemic stroke caused by atypical thrombotic thrombocytopenic purpura

Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice

Postreactivation glucocorticoids impair recall of established fear memory.

Psychometric Study of the Social Responsiveness Scale in Phelan-McDermid Syndrome

Pten regulates neuronal arborization and social interaction in mice

RIM1alpha and interacting proteins involved in presynaptic plasticity mediate prepulse inhibition and additional behaviors linked to schizophrenia

RIM1alpha phosphorylation at serine-413 by protein kinase A is not required for presynaptic long-term plasticity or learning

Region-specific deletions of RIM1 reproduce a subset of global RIM1α(-/-) phenotypes

Regulation of hippocampal and behavioral excitability by cyclin-dependent kinase 5.

Schizophrenia-relevant behavioral testing in rodent models: a uniquely human disorder?

Studies with synthetic peptide substrates derived from the neuronal protein neurogranin reveal structural determinants of potency and selectivity for protein kinase C

Temporally specified genetic ablation of neurogenesis impairs cognitive recovery after traumatic brain injury

The presynaptic active zone protein RIM1alpha is critical for normal learning and memory