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List of works by Nigel Mongan

A Fibromyxoid Stromal Response is Associated with Muscle Invasion in Canine Urothelial Carcinoma

scientific article published on 17 May 2019

A key genomic subtype associated with lymphovascular invasion in invasive breast cancer

scientific article published on 22 May 2019

A novel prognostic two-gene signature for triple negative breast cancer

scientific article published on 13 May 2020

A predictive model for canine dilated cardiomyopathy-a meta-analysis of Doberman Pinscher data

scientific article

A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors.

scientific article published on 23 August 2013

All-trans retinoic acid (ATRA)-induced TFEB expression is required for myeloid differentiation in acute promyelocytic leukemia (APL)

scientific article published on 13 January 2020

Alternative Splicing Events and Their Clinical Significance in Colorectal Cancer: Targeted Therapeutic Opportunities

scientific article published in 2023

An extensive and diverse gene family of nicotinic acetylcholine receptor alpha subunits in Caenorhabditis elegans.

scientific article

Androgen dependent mechanisms of pro-angiogenic networks in placental and tumor development

scientific article published on 20 February 2017

Androgen insensitivity syndrome.

scientific article

Androgen receptor expression is inversely correlated with pathologic tumor stage in bladder cancer.

scientific article

Androgen receptor gene CAG repeat polymorphism in the development of ovarian hyperandrogenism.

scientific article published on July 2003

Anthelmintic actions on homomer-forming nicotinic acetylcholine receptor subunits: chicken alpha7 and ACR-16 from the nematode Caenorhabditis elegans.

scientific article published in January 2000

Association of Aromatase With Bladder Cancer Stage and Long-Term Survival: New Insights Into the Hormonal Paradigm in Bladder Cancer.

scientific article published on 27 May 2016

CARM1 (PRMT4) Acts as a Transcriptional Coactivator during Retinoic Acid-Induced Embryonic Stem Cell Differentiation

scientific article published on 25 August 2018

CDK1 interacts with RARγ and plays an important role in treatment response of acute myeloid leukemia

scientific article published on 21 March 2013

Clinical trial update and novel therapeutic approaches for metastatic prostate cancer.

scientific article published on January 2011

Clinicopathological and prognostic significance of Ras association and pleckstrin homology domains 1 (RAPH1) in breast cancer

scientific article published on 28 July 2018

Combined HER3-EGFR score in triple-negative breast cancer provides prognostic and predictive significance superior to individual biomarkers

scientific article published on 20 February 2020

Comparative review of human and canine osteosarcoma: morphology, epidemiology, prognosis, treatment and genetics.

scientific article published on 24 October 2017

Complete androgen insensitivity syndrome caused by a novel mutation in the ligand-binding domain of the androgen receptor: functional characterization.

scientific article

Cyclin A1 and P450 Aromatase Promote Metastatic Homing and Growth of Stem-like Prostate Cancer Cells in the Bone Marrow.

scientific article published on 26 February 2016

Decreased expression of the human stem cell marker, Rex-1 (zfp-42), in renal cell carcinoma

scientific article

Detection and analysis of RNA methylation

scientific article published on 26 April 2019

Diverse actions of retinoid receptors in cancer prevention and treatment.

scientific article published on 18 July 2007

Estrogen receptor-β expression and pharmacological targeting in bladder cancer.

scientific article published on 23 April 2013

Evidence that luteinising hormone receptor polymorphisms may contribute to male undermasculinisation

scientific article published in July 2002

Expression of NAD(P)H quinone dehydrogenase 1 (NQO1) is increased in the endometrium of women with endometrial cancer and women with polycystic ovary syndrome.

scientific article

Expression of VEGF and its receptors VEGFR1/VEGFR2 is associated with invasiveness of bladder cancer

scientific article published in June 2013

Expression of cyclin d1 and its association with disease characteristics in bladder cancer

scientific article

Five novel androgen receptor gene mutations associated with complete androgen insensitivity syndrome

scientific article published on 01 March 2006

Genetic evidence to exclude the androgen receptor-polyglutamine associated coactivator, ARA-24, as a cause of male undermasculinisation

scientific article published on 01 December 2001

Genetics of Human and Canine Dilated Cardiomyopathy

scientific article

Heterodimers of photoreceptor-specific nuclear receptor (PNR/NR2E3) and peroxisome proliferator-activated receptor-γ (PPARγ) are disrupted by retinal disease-associated mutations

scientific article published on 16 March 2017

Heterogeneity of tumour-infiltrating lymphocytes in breast cancer and its prognostic significance

scientific article published on 09 October 2018

Human androgen receptor gene ligand-binding-domain mutations leading to disrupted interaction between the N- and C-terminal domains

scientific article published in April 2006

Immunosuppressive properties of cytochalasin B-induced membrane vesicles of mesenchymal stem cells: comparing with extracellular vesicles derived from mesenchymal stem cells

scientific article published on 01 July 2020

Impact of breast cancer grade discordance on prediction of outcome

scientific article published on 19 September 2018

Increased expression of the polycomb group gene, EZH2, in transitional cell carcinoma of the bladder

scientific article

Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic modulation

scientific article published on 15 May 2015

Inhibition of UBE2L6 attenuates ISGylation and impedes ATRA-induced differentiation of leukemic cells

scientific article published on 10 December 2019

Jak3, STAT3, and STAT5 inhibit expression of miR-22, a novel tumor suppressor microRNA, in cutaneous T-Cell lymphoma

scientific article published on 12 May 2015

Lentiviral-Mediated shRNA Approaches: Applications in Cellular Differentiation and Autophagy

scientific article published on 01 January 2019

Ligase 1 is a predictor of platinum resistance and its blockade is synthetically lethal in XRCC1 deficient epithelial ovarian cancers

scientific article published on 25 July 2021

Malignant inflammation in cutaneous T-cell lymphoma-a hostile takeover

scientific article published on 07 October 2016

Metadherin: A Therapeutic Target in Multiple Cancers

scientific article published on 03 May 2019

MiR137 is an androgen regulated repressor of an extended network of transcriptional coregulators

scientific article

Molecular Characterisation of Canine Osteosarcoma in High Risk Breeds

scientific article published on 25 August 2020

Molecular characterization of adipose tissue in the African elephant (Loxodonta africana)

scientific article (publication date: 2014)

Multiple Genetic Associations with Irish Wolfhound Dilated Cardiomyopathy.

scientific article

Mutations in ZMYND10, a gene essential for proper axonemal assembly of inner and outer dynein arms in humans and flies, cause primary ciliary dyskinesia

scientific article

Novel alpha7-like nicotinic acetylcholine receptor subunits in the nematode Caenorhabditis elegans

scientific article

Overcoming drug resistance and treating advanced prostate cancer

scientific article

Overexpression of the cancer stem cell marker CD133 confers a poor prognosis in invasive breast cancer

scientific article published on 15 December 2018

Phase 1/2 clinical trial of interferon alpha2b and weekly liposome-encapsulated all-trans retinoic acid in patients with advanced renal cell carcinoma.

scientific article published in September 2007

Phase I trial of ATRA-IV and Depakote in patients with advanced solid tumor malignancies

scientific article

Polycomb recruitment attenuates retinoic acid-induced transcription of the bivalent NR2F1 gene

scientific article published on 10 May 2013

Predicting puberty in partial androgen insensitivity syndrome: Use of clinical and functional androgen receptor indices

scientific article published on 11 October 2018

Prognostic significance of KN motif and ankyrin repeat domains 1 (KANK1) in invasive breast cancer

scientific article published on 02 November 2019

Promoter-dependent activity on androgen receptor N-terminal domain mutations in androgen insensitivity syndrome.

scientific article

Reduced lecithin: retinol acyltransferase expression correlates with increased pathologic tumor stage in bladder cancer

scientific article

Reduced neonatal mortality in Meishan piglets: a role for hepatic fatty acids?

scientific article

Regulation of stem cell pluripotency and differentiation involves a mutual regulatory circuit of the NANOG, OCT4, and SOX2 pluripotency transcription factors with polycomb repressive complexes and stem cell microRNAs.

scientific article published on September 2009

Regulation of vascular endothelial growth factor in prostate cancer.

scientific article published on 13 April 2015

Retinoid X receptor gamma (RXRG) is an independent prognostic biomarker in ER-positive invasive breast cancer

scientific article published on 27 September 2019

Retinoid receptor signaling and autophagy in acute promyelocytic leukemia

scientific article published on 30 March 2014

Role of NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex 4-Like 2 in Clear Cell Renal Cell Carcinoma

scientific article published on 18 January 2016

Role of androgen receptor and associated lysine-demethylase coregulators, LSD1 and JMJD2A, in localized and advanced human bladder cancer.

scientific article published on 11 March 2011

STAT5 induces miR-21 expression in cutaneous T cell lymphoma.

scientific article published on 18 June 2016

Staphylococcal enterotoxin A (SEA) stimulates STAT3 activation and IL-17 expression in cutaneous T-cell lymphoma

scientific article published on 5 January 2016

Steroid receptor coactivator-3 glutamine repeat polymorphism and the androgen insensitivity syndrome

scientific article published in February 2003

TP53 copy number expansion is associated with the evolution of increased body size and an enhanced DNA damage response in elephants

scientific article

Targeted suppression of AR-V7 using PIP5K1α inhibitor overcomes enzalutamide resistance in prostate cancer cells.

scientific article published on 31 August 2016

The Expression of IL-21 Is Promoted by MEKK4 in Malignant T Cells and Associated with Increased Progression Risk in Cutaneous T-Cell Lymphoma.

scientific article published on 20 January 2016

The androgen receptor and stem cell pathways in prostate and bladder cancers (review)

scientific article

The dog as an animal model for bladder and urethral urothelial carcinoma: Comparative epidemiology and histology

scientific article published on 30 May 2018

The lysine specific demethylase-1 (LSD1/KDM1A) regulates VEGF-A expression in prostate cancer

scientific article (publication date: June 2013)

The molecular mechanisms underlying reduced E-cadherin expression in invasive ductal carcinoma of the breast: high throughput analysis of large cohorts

scientific article published on 13 February 2019

The prognostic significance of wild-type isocitrate dehydrogenase 2 (IDH2) in breast cancer

scientific article published on 10 October 2019

The putative human stem cell marker, Rex-1 (Zfp42): structural classification and expression in normal human epithelial and carcinoma cell cultures

scientific article

The role of HIF1α in renal cell carcinoma tumorigenesis.

scientific article

The role of PIP5K1α/pAKT and targeted inhibition of growth of subtypes of breast cancer using PIP5K1α inhibitor

Two de novo mutations in the AR gene cause the complete androgen insensitivity syndrome in a pair of monozygotic twins

scientific article published in March 2002

Two zinc finger proteins with functions in m6A writing interact with HAKAI

scientific article published on 02 March 2022

Understanding mechanisms of disease development: next generation pathology?

scientific article

Untangling the clinicopathological significance of MRE11-RAD50-NBS1 complex in sporadic breast cancers

scientific article published on 15 November 2021

Up-regulation of genes involved in the insulin signalling pathway (IGF1, PTEN and IGFBP1) in the endometrium may link polycystic ovarian syndrome and endometrial cancer

scientific article published on 20 January 2016

Utility of ankyrin 3 as a prognostic marker in androgen-receptor-positive breast cancer

scientific article published on 02 April 2019

Valproic acid, in combination with all-trans retinoic acid and 5-aza-2'-deoxycytidine, restores expression of silenced RARbeta2 in breast cancer cells.

scientific article

m6A potentiates Sxl alternative pre-mRNA splicing for robust Drosophila sex determination.

scientific article published on 30 November 2016