List of works by Rino Ragno

2,6-Bis(3,4,5-trihydroxybenzylydene) derivatives of cyclohexanone: novel potent HIV-1 integrase inhibitors that prevent HIV-1 multiplication in cell-based assays

scientific article published on January 2004

2-(Alkyl/aryl)amino-6-benzylpyrimidin-4(3H)-ones as inhibitors of wild-type and mutant HIV-1: enantioselectivity studies

scientific article

3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-alkylamides as a new class of synthetic histone deacetylase inhibitors. 1. Design, synthesis, biological evaluation, and binding mode studies performed through three different docking procedures

scientific article published on February 2003

3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamides as a new class of synthetic histone deacetylase inhibitors. 2. Effect of pyrrole-C2 and/or -C4 substitutions on biological activity

scientific article published on February 2004

3-(4-Aroyl-1-methyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides as a new class of synthetic histone deacetylase inhibitors. 3. Discovery of novel lead compounds through structure-based drug design and docking studies

scientific article published on March 2004

3-(4-aroyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides, a new class of synthetic histone deacetylase inhibitors

scientific article published in June 2001

3-D QSAR Studies on Histone Deacetylase Inhibitors. A GOLPE/GRID Approach on Different Series of Compounds

scientific article published on 01 May 2006

3-D QSAutogrid/R: an alternative procedure to build 3-D QSAR models. Methodologies and applications

scientific article published on 13 June 2012

5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3H)-ones, a new series of potent, broad-spectrum non-nucleoside reverse transcriptase inhibitors belonging to the DABO family.

scientific article published on March 2005

5-Alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a series of anti-HIV-1 agents of the dihydro-alkoxy-benzyl-oxopyrimidine family with peculiar structure-activity relationship profile

scientific article published on 17 July 2008

6-aryl-2,4-dioxo-5-hexenoic acids, novel integrase inhibitors active against HIV-1 multiplication in cell-based assays

scientific article published in April 2004

A Combination of Molecular Dynamics and Docking Calculations to Explore the Binding Mode of ADS-J1, a Polyanionic Compound Endowed with Anti-HIV-1 Activity

article

Ab-initio and experimental study of pentose sugar dehydration mechanism in the gas phase

scientific article published on 8 February 2018

Antibacterial activity of essential oils mixture against PSA.

scientific article

Antifungal Agents, II: Synthesis and Antifungal Activities of Aryl-1H-pyrrol-2-yl-1H-imidazol-1-yl-methane Derivatives with Unsaturated Chains

scientific article published on 01 September 1993

Antimicrobial Essential Oil Formulation: Chitosan Coated Nanoemulsions for Nose to Brain Delivery

scientific article published on 17 July 2020

Antimicrobial and Antibiofilm Activity and Machine Learning Classification Analysis of Essential Oils from Different Mediterranean Plants against Pseudomonas aeruginosa.

scientific article published on 23 February 2018

Antimycobacterial pyrroles: synthesis, anti-Mycobacterium tuberculosis activity and QSAR studies.

scientific article published in June 2000

Aroyl-pyrrolyl hydroxyamides: influence of pyrrole C4-phenylacetyl substitution on histone deacetylase inhibition

scientific article published on February 2006

Biaryl tetrazolyl ureas as inhibitors of endocannabinoid metabolism: modulation at the N-portion and distal phenyl ring

scientific article

Binding mode analysis of 3-(4-benzoyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamide: a new synthetic histone deacetylase inhibitor inducing histone hyperacetylation, growth inhibition, and terminal cell differentiation

scientific article published in April 2002

Binding of azole drugs to heme: A combined MS/MS and computational approach

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-2.

scientific article published on 28 December 2017

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-5

scientific article published on 30 June 2019

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-6

scientific article published on 28 December 2019

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes⁻4

scientific article published on 31 December 2018

CYP19 (aromatase): Exploring the scaffold flexibility for novel selective inhibitors

scientific article published in September 2008

Calamintha nepeta (L.) Savi and its Main Essential Oil Constituent Pulegone: Biological Activities and Chemistry. ⬇️

scientific article published on 14 February 2017

Carotenoid content of Goji berries: CIELAB, HPLC-DAD analyses and quantitative correlation

scientific article published on 15 June 2018

Chemical Composition and Anti-Candida Activity of Mentha suaveolens Ehrh. Essential Oils Obtained by Different Distillation Processes

scientific article published in 2023

Chemical and Antimicrobial Analyses of Sideritis romana L. subsp. purpurea (Tal. ex Benth.) Heywood, an Endemic of the Western Balkan

scientific article published on 23 August 2017

Chemically Modified Multiwalled Carbon Nanotubes Electrodes with Ferrocene Derivatives through Reactive Landing

Class II-selective histone deacetylase inhibitors. Part 2: Alignment-independent GRIND 3-D QSAR, homology and docking studies

scientific article published on 27 May 2007

Combining 3-D quantitative structure-activity relationship with ligand based and structure based alignment procedures for in silico screening of new hepatitis C virus NS5B polymerase inhibitors

scientific article published in April 2010

Comprehensive model of wild-type and mutant HIV-1 reverse transciptases.

scientific article

Computer-aided design, synthesis, and anti-HIV-1 activity in vitro of 2-alkylamino-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as novel potent non-nucleoside reverse transcriptase inhibitors, also active against the Y181C

scientific article published on February 2004

Decreasing acidity in a series of aldose reductase inhibitors: 2-Fluoro-4-(1H-pyrrol-1-yl)phenol as a scaffold for improved membrane permeation

scientific article published on 26 February 2014

Design, Molecular Modeling, Synthesis, and Anti-HIV-1 Activity of New Indolyl Aryl Sulfones. Novel Derivatives of the Indole-2-carboxamide

article

Design, synthesis and QSAR studies on N-aryl heteroarylisopropanolamines, a new class of non-peptidic HIV-1 protease inhibitors

scientific article

Design, synthesis and biological evaluation of carboxy analogues of arginine methyltransferase inhibitor 1 (AMI-1).

scientific article published in March 2010

Design, synthesis and biological evaluation of new classes of thieno[3,2-d]pyrimidinone and thieno[1,2,3]triazine as inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2).

scientific article published on 19 March 2013

Design, synthesis, and biological evaluation of sirtinol analogues as class III histone/protein deacetylase (Sirtuin) inhibitors

scientific article

Design, synthesis, biological evaluation, and molecular modeling studies of TIBO-like cyclic sulfones as non-nucleoside HIV-1 reverse transcriptase inhibitors

scientific article published on January 2006

Discovery of the First Human Arylsulfatase A Reversible Inhibitor Impairing Mouse Oocyte Fertilization

scientific article published on 02 April 2020

Disruptor of telomeric silencing 1-like (DOT1L): disclosing a new class of non-nucleoside inhibitors by means of ligand-based and structure-based approaches

scientific article published on 15 January 2018

Docking and 3-D QSAR studies on indolyl aryl sulfones. Binding mode exploration at the HIV-1 reverse transcriptase non-nucleoside binding site and design of highly active N-(2-hydroxyethyl)carboxamide and N-(2-hydroxyethyl)carbohydrazide derivatives

scientific article published in January 2005

Effect of α-Methoxy Substitution on the Anti-HIV Activity of Dihydropyrimidin-4(3 H)-ones

scientific article published on 20 December 2018

Effects of Mentha suaveolens Essential Oil Alone or in Combination with Other Drugs in Candida albicans

scientific article published on 27 February 2014

Effects of Mentha suaveolens essential oil on Chlamydia trachomatis

scientific article

Essential Oil Extraction, Chemical Analysis and Anti-Candida Activity of Calamintha nepeta (L.) Savi subsp. glandulosa (Req.) Ball-New Approaches.

scientific article published on 26 January 2017

Essential Oils Biofilm Modulation Activity and Machine Learning Analysis on <i>Pseudomonas aeruginosa</i> Isolates from Cystic Fibrosis Patients

scientific article published on 24 April 2022

Essential Oils Biofilm Modulation Activity, Chemical and Machine Learning Analysis. Application on <i>Staphylococcus aureus</i> Isolates from Cystic Fibrosis Patients

scientific article published on 04 December 2020

Essential Oils and Their Main Chemical Components: The Past 20 Years of Preclinical Studies in Melanoma

scientific article published on 16 September 2020

Essential oils against bacterial isolates from cystic fibrosis patients by means of antimicrobial and unsupervised machine learning approaches

scientific article published on 14 February 2020

Experimental Data Based Machine Learning Classification Models with Predictive Ability to Select in Vitro Active Antiviral and Non-Toxic Essential Oils

scientific article published on 25 May 2020

Exploring the role of 2-chloro-6-fluoro substitution in 2-alkylthio-6-benzyl-5-alkylpyrimidin-4(3H)-ones: effects in HIV-1-infected cells and in HIV-1 reverse transcriptase enzymes

scientific article

Gas-phase basicity of 2-furaldehyde

scientific article published on 01 November 2012

Genotoxicity assessment of piperitenone oxide: An in vitro and in silico evaluation

scientific article

HIV-reverse transcriptase inhibition: inclusion of ligand-induced fit by cross-docking studies

scientific article published in January 2005

High Potency of Essential Oil against Multi-Drug Resistant Gram-Negative Bacteria and Methicillin-Resistant

scientific article published on 09 October 2018

High potency of indolyl aryl sulfone nonnucleoside inhibitors towards drug-resistant human immunodeficiency virus type 1 reverse transcriptase mutants is due to selective targeting of different mechanistic forms of the enzyme.

scientific article

Histone deacetylase inhibitors: structure-based modeling and isoform-selectivity prediction

scientific article published on 19 July 2012

Histone deacetylation in epigenetics: an attractive target for anticancer therapy

scientific article

Hsp90 inhibitors, part 1: definition of 3-D QSAutogrid/R models as a tool for virtual screening.

scientific article

Hsp90 inhibitors, part 2: combining ligand-based and structure-based approaches for virtual screening application

scientific article published on 04 March 2014

Identification of Inhibitors to Trypanosoma cruzi Sirtuins Based on Compounds Developed to Human Enzymes ⬇️

scientific article published on 22 May 2020

Identification of glutathione-methacrylates adducts in gingival fibroblasts and erythrocytes by HPLC–MS and capillary electrophoresis

scientific article published on 02 March 2011

Identification of small-molecule inhibitors of the XendoU endoribonucleases family

scientific article

In vitro inhibition of herpes simplex virus type 1 replication by Mentha suaveolens essential oil and its main component piperitenone oxide

scientific article published on 11 March 2014

In-Vitro Evaluation of Different Antimicrobial Combinations with and without Colistin Against Carbapenem-Resistant Acinetobacter Baumannii

scientific article published on 03 March 2019

Inhibition of hepatitis C virus NS5B polymerase by S-trityl-L-cysteine derivatives.

scientific article published on 12 January 2012

Investigation on QSAR and binding mode of a new class of human rhinovirus-14 inhibitors by CoMFA and docking experiments

scientific article published on 01 October 1996

Lycium barbarum polysaccharides: Extraction, purification, structural characterisation and evidence about hypoglycaemic and hypolipidaemic effects. A review

scientific article published on 01 February 2018

Machine Learning Analyses on Data including Essential Oil Chemical Composition and In Vitro Experimental Antibiofilm Activities against Staphylococcus Species

article

Mentha suaveolens Ehrh. (Lamiaceae) Essential Oil and Its Main Constituent Piperitenone Oxide: Biological Activities and Chemistry

scientific article

Molecular Modeling of Azole Antifungal Agents Active againstCandida albicans. 1. A Comparative Molecular Field Analysis Study1

scientific article published on 01 March 1996

Multidisciplinary Approach to Determine the Optimal Time and Period for Extracting the Essential Oil from Mentha suaveolens Ehrh

scientific article published on 26 May 2015

New pyrrole-based histone deacetylase inhibitors: binding mode, enzyme- and cell-based investigations

scientific article published on 12 September 2008

Novel cinnamyl hydroxyamides and 2-aminoanilides as histone deacetylase inhibitors: apoptotic induction and cytodifferentiation activity

scientific article published on 4 March 2011

Pharmacophore Assessment Through 3-D QSAR: Evaluation of the Predictive Ability on New Derivatives by the Application on a Series of Antitubercular Agents

scientific article published on 17 May 2013

RIP1-HAT1-SirT complex identification and targeting in treatment and prevention of cancer.

scientific article published on 13 March 2018

Shmt2: A Stat3 Signaling New Player in Prostate Cancer Energy Metabolism

scientific article published on 06 September 2019

Small molecule inhibitors of histone arginine methyltransferases: homology modeling, molecular docking, binding mode analysis, and biological evaluations

scientific article

Small-Molecule Interferon Inducers. Toward the Comprehension of the Molecular Determinants through Ligand-Based Approaches

scientific article published on 01 July 2009

Synthesis and Biological Properties of Novel, Uracil-Containing Histone Deacetylase Inhibitors

scientific article published on 01 October 2006

Synthesis and biological evaluation of enantiomerically pure pyrrolyl-oxazolidinones as a new class of potent and selective monoamine oxidase type A inhibitors

scientific article

Synthesis and biological properties of novel 2-aminopyrimidin-4(3H)-ones highly potent against HIV-1 mutant strains

scientific article

Synthesis and biological validation of novel synthetic histone/protein methyltransferase inhibitors

scientific article published on July 2007

Synthesis and evaluation of new tripeptide phosphonate inhibitors of MMP-8 and MMP-2.

scientific article

Synthesis of new disoxaril analogues with potent and selective anti-human rhinovirus 14 activity

scientific article published in 1991

Synthesis, biological evaluation and docking analysis of a new series of methylsulfonyl and sulfamoyl acetamides and ethyl acetates as potent COX-2 inhibitors

scientific article published on 26 December 2014

Synthesis, biological evaluation, and binding mode of novel 1-[2-(diarylmethoxy)ethyl]-2-methyl-5-nitroimidazoles targeted at the HIV-1 reverse transcriptase.

scientific article published on April 2002

Targeting the anti-apoptotic Bcl-2 family proteins: machine learning virtual screening and biological evaluation of new small molecules

scientific article published on 28 February 2022

The Targeted Pesticides as Acetylcholinesterase Inhibitors: Comprehensive Cross-Organism Molecular Modelling Studies Performed to Anticipate the Pharmacology of Harmfulness to Humans In Vitro

scientific article published on 30 August 2018

The tumor marker human placental protein 11 is an endoribonuclease

scientific article

Transcriptomic and genomic studies classify NKL54 as a histone deacetylase inhibitor with indirect influence on MEF2-dependent transcription

scientific article published on 01 March 2022

Understanding the Molecular Determinant of Reversible Human Monoamine Oxidase B Inhibitors Containing 2H-Chromen-2-One Core: Structure-Based and Ligand-Based Derived Three-Dimensional Quantitative Structure-Activity Relationships Predictive Models

scientific article

Vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitors: development and validation of predictive 3-D QSAR models through extensive ligand- and structure-based approaches

scientific article published on 21 July 2015

[[[(Thienylcarbonyl)alkyl]oxy]phenyl]- and [[[(pyrrylcarbonyl)alkyl]oxy]phenyl]oxazoline derivatives with potent and selective antihuman rhinovirus activity.

scientific article published on March 1995

www.3d-qsar.com: a web portal that brings 3-D QSAR to all electronic devices-the Py-CoMFA web application as tool to build models from pre-aligned datasets

scientific article published on 01 September 2019

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