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List of works by Piero Portincasa

(13)C-octanoic acid breath test (OBT) with a new test meal (EXPIROGer): Toward standardization for testing gastric emptying of solids

scientific article published on 29 January 2010

A novel cluster of patients with Familial Mediterranean Fever (FMF) in southern Italy

scientific article

A novel therapeutic effect of statins on nephrogenic diabetes insipidus

scientific article

A silybin-phospholipids complex counteracts rat fatty liver degeneration and mitochondrial oxidative changes.

scientific article published on May 2013

Absence of apolipoprotein E4 genotype, good gallbladder motility and presence of solitary stones delay rather than prevent gallstone recurrence after extracorporeal shock wave lithotripsy

scientific article published in July 2001

Adaptation of subcellular glutathione detoxification system to stress conditions in choline-deficient diet induced rat fatty liver.

scientific article published in November 2003

Adefovir dipivoxyl for the treatment of delta-related liver cirrhosis

scientific article published on 01 August 2006

Altered distribution of caveolin-1 in early liver steatosis.

scientific article published on 20 January 2011

Altered expression and distribution of aquaporin-9 in the liver of rat with obstructive extrahepatic cholestasis

scientific article published on 31 July 2008

Altered membrane glycoprotein targeting in cholestatic hepatocytes

scientific article published on 22 March 2010

An Update on the Lithogenic Mechanisms of Cholecystokinin a Receptor (CCKAR), an Important Gallstone Gene for <i>Lith13</i>

scientific article published on 29 November 2020

Anti-ApoA-1 predicts resistance to waist circumference reduction after Mediterranean Diet

scientific article published on 12 September 2020

Apolipoprotein E4 genotype and gallbladder motility influence speed of gallstone clearance and risk of recurrence after extracorporeal shock-wave lithotripsy

scientific article published on 01 September 1996

Aquaporins in the hepatobiliary tract. Which, where and what they do in health and disease.

scientific article published on January 2008

Assessing the nutritional status of older individuals in family practice: Evaluation and implications for management

scientific article published on 17 December 2014

Basolateral Ca2+-dependent K+-channels play a key role in Cl- secretion induced by taurodeoxycholate from colon mucosa.

scientific article

Behavior of various cholesterol crystals in bile from patients with gallstones

scientific article published on 01 April 1996

Beneficial effects of oral tilactase on patients with hypolactasia

scientific article published in November 2008

Bile Acids and GPBAR-1: Dynamic Interaction Involving Genes, Environment and Gut Microbiome

scientific article published on 30 November 2020

Biliary pronucleating proteins and apolipoprotein E in cholesterol and pigment stone patients

scientific article

Biliary proteins and their redox status changes in gallstone patients.

scientific article published on 28 July 2009

Biochemical mechanisms in drug-induced liver injury: certainties and doubts.

scientific article published on October 2009

Bovine pericardium patch wrapping intestinal anastomosis improves healing process and prevents leakage in a pig model

scientific article (publication date: 2014)

COVID-19 and nonalcoholic fatty liver disease: two intersecting pandemics

scientific article published on 26 June 2020

COVID-19, internists and resilience: the north-south Italy outbreak

scientific article published on 01 June 2020

COVID-19: Specific and Non-Specific Clinical Manifestations and Symptoms: The Current State of Knowledge

scientific article published on 05 June 2020

COVID-19: focus on the lungs but do not forget the gastrointestinal tract

scientific article published on 14 May 2020

Cardiac mitochondrial dysfunction during hyperglycemia--the role of oxidative stress and p66Shc signaling

scientific article published on 07 July 2012

Caveolin-1 and mitochondrial alterations in regenerating rat liver

scientific journal article

Changes of gallbladder and gastric dynamics in patients with acute hepatitis A.

scientific article published in July 2001

Chemical Characterization, Gastrointestinal Motility and Sensory Evaluation of Dark Chocolate: A Nutraceutical Boosting Consumers' Health

scientific article published on 28 March 2020

Chocolate, "Food of the Gods": History, Science, and Human Health

scientific article published on 06 December 2019

Cholecystectomy: a way forward and back to metabolic syndrome?

scientific article published in January 2018

Cholesterol cholelithiasis: part of a systemic metabolic disease, prone to primary prevention

scientific article published on 27 November 2018

Cholesterol crystallization in human gallbladder bile: relation to gallstone number, bile composition, and apolipoprotein E4 isoform

scientific article published in June 1998

Cholesterol gallstone disease.

scientific article published on July 2006

Cholesterol saturation rather than phospholipid/bile salt ratio or protein content affects crystallization sequences in human gallbladder bile

scientific article published in October 2004

Chronic ethanol administration induces oxidative alterations and functional impairment of pancreatic mitochondria in the rat

scientific article published on 01 November 1999

Circulating CRP Levels Are Associated with Epicardial and Visceral Fat Depots in Women with Metabolic Syndrome Criteria

scientific article published on 27 November 2019

Concomitant, sequential, and hybrid therapy for H. pylori eradication: a pilot study

scientific article published on 6 June 2013

Contractility in vitro and mitochondrial response in small and large rabbit bowel after anastomosis

scientific article published on 4 February 2002

Coordinate regulation of gallbladder motor function in the gut-liver axis.

scientific article published on June 2008

Current pharmacological treatment of nonalcoholic fatty liver

scientific article published on January 2006

Current treatments of primary sclerosing cholangitis.

scientific article published on January 2007

Current views on genetics and epigenetics of cholesterol gallstone disease

scientific article published on 14 April 2013

Dietary choline deprivation impairs rat brain mitochondrial function and behavioral phenotype

scientific article

Dissecting the genetic heterogeneity of gallbladder stone formation

scientific article published on 02 May 2011

Does mediastinal extension of the goiter increase morbidity of total thyroidectomy? A multicenter study of 19,662 patients

scientific article published on 19 February 2011

Drug reaction with eosinophilia and systemic symptoms caused by lenalidomide

scientific article published on 01 November 2012

Drugs affecting biliary lipid secretion and gallbladder motility: their potential role in gallstone treatment and prevention

scientific article

Effect of dietary restriction and N-acetylcysteine supplementation on intestinal mucosa and liver mitochondrial redox status and function in aged rats

scientific article published in September 2004

Effect of ezetimibe on the prevention and dissolution of cholesterol gallstones

scientific article published on 10 March 2008

Effect of gallbladder hypomotility on cholesterol crystallization and growth in CCK-deficient mice

scientific article

Effects of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001 in IBS patients

scientific article published on 12 February 2020

Effects of dietary education, followed by a tailored fructose-restricted diet in adults with fructose malabsorption

scientific article

Effects of growth hormone deficiency and recombinant growth hormone therapy on postprandial gallbladder motility and cholecystokinin release

scientific article

Effects of ursodeoxycholic acid therapy on in vitro gallbladder contractility in patients with cholesterol gallstones

scientific article published in January 1999

Efficacy and tolerability of cinitapride in the treatment of functional dyspepsia and delayed gastric emptying

scientific article published on 9 October 2009

Estrogen induces two distinct cholesterol crystallization pathways by activating ERα and GPR30 in female mice.

scientific article

Exercising the hepatobiliary-gut axis. The impact of physical activity performance

scientific article published on 14 June 2018

Exploring liver mitochondrial function by ¹³C-stable isotope breath tests: implications in clinical biochemistry

scientific article published in January 2015

Expression and subcellular localization of the AQP8 and AQP1 water channels in the mouse gall-bladder epithelium

scientific article published in June 2005

Ezetimibe prevents the formation of oestrogen-induced cholesterol gallstones in mice

scientific article

Familial mediterranean fever: a fascinating model of inherited autoinflammatory disorder

scientific article published on 14 October 2013

Fat, epigenome and pancreatic diseases. Interplay and common pathways from a toxic and obesogenic environment.

scientific article

Fecal microRNA profile in patients with colorectal carcinoma before and after curative surgery

scientific article published on 20 May 2015

Functional Relationship between Leptin and Nitric Oxide in Metabolism

scientific article published on 06 September 2019

Gallbladder and gastric motility in obese newborns, pre-adolescents and adults

scientific article published in August 2012

Gallbladder emptying in vivo, bile composition, and nucleation of cholesterol crystals in patients with cholesterol gallstones

scientific article

Gallbladder histopathology during murine gallstone formation: relation to motility and concentrating function.

scientific article published on 13 October 2005

Gallbladder motility and cholesterol crystallization in bile from patients with pigment and cholesterol gallstones

scientific article published in April 2000

Gallbladder motility and functional gastrointestinal disorders

scientific article

Gallbladder motor function in gallstone patients: sonographic and in vitro studies on the role of gallstones, smooth muscle function and gallbladder wall inflammation.

scientific article published in September 1994

Gallstone disease: Symptoms and diagnosis of gallbladder stones

scientific article

Gastrointestinal defects in gallstone and cholecystectomized patients

scientific article published on 29 January 2019

Gastrointestinal symptoms and motility disorders in patients with systemic scleroderma

scientific article

Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis

scientific journal article

Glutathione peroxidase, thioredoxin, and membrane protein changes in erythrocytes predict ribavirin-induced anemia.

scientific article published in October 2005

Gut Microbiota between Environment and Genetic Background in Familial Mediterranean Fever (FMF)

scientific article published on 03 September 2020

Helicobacter pylori Virulence Factors-Mechanisms of Bacterial Pathogenicity in the Gastric Microenvironment

scientific article published on 25 December 2020

High-fat diet alters the oligosaccharide chains of colon mucins in mice

scientific article published on 26 April 2014

Hydrophilic bile salts enhance differential distribution of sphingomyelin and phosphatidylcholine between micellar and vesicular phases: potential implications for their effects in vivo

scientific article published in April 2001

Immunological Aspects of the Tumor Microenvironment and Epithelial-Mesenchymal Transition in Gastric Carcinogenesis

scientific article published on 06 April 2020

In situ characterization of O-linked glycans of Muc2 in mouse colon.

scientific article

Incorporation of cholesterol in sphingomyelin- phosphatidylcholine vesicles has profound effects on detergent-induced phase transitions.

scientific article published on July 2002

Increase of the Adiponectin/Leptin Ratio in Patients with Obesity and Type 2 Diabetes after Roux-en-Y Gastric Bypass

scientific article published on 03 September 2019

Increased Colonic Permeability and Lifestyles as Contributing Factors to Obesity and Liver Steatosis

scientific article published on 21 February 2020

Indomethacin enhances bile salt detergent activity: relevance for NSAIDs-induced gastrointestinal mucosal injury

scientific article published on 01 April 2006

Indomethacin-induced ileitis is associated with tensiometric, vascular and oxidative changes in the experimental rat model.

scientific article published in April 2005

Influence on functional parameters of intestinal tract induced by short-term exposure to fumonisins contaminated corn chyme samples

scientific article published on 28 January 2014

Intestinal absorption, hepatic synthesis, and biliary secretion of cholesterol: where are we for cholesterol gallstone formation?

scientific article published on 04 April 2012

Intestinal mucosal damage caused by non-steroidal anti-inflammatory drugs: role of bile salts.

scientific article published on 31 January 2007

Intestinal permeability in patients with chronic liver diseases: Its relationship with the aetiology and the entity of liver damage.

scientific article

Ion transport across the gallbladder epithelium.

scientific article

Is it possible to predict the clinical course of gallstone disease? Usefulness of gallbladder motility evaluation in a clinical setting

scientific article published on 01 November 2006

Lith genes and genetic analysis of cholesterol gallstone formation

scientific article published on June 2010

Liver Steatosis, Gut-Liver Axis, Microbiome and Environmental Factors. A Never-Ending Bidirectional Cross-Talk

scientific article published on 14 August 2020

Liver breath tests non-invasively predict higher stages of non-alcoholic steatohepatitis

scientific article published on 01 August 2006

Liver function as assessed by breath tests in patients with hepatocellular carcinoma.

scientific article published on 21 November 2008

Liver glycerol permeability and aquaporin-9 are dysregulated in a murine model of Non-Alcoholic Fatty Liver Disease

scientific article

Long-term functional assessment of antegrade colonic enema for combined incontinence and constipation using a modified Marsh and Kiff technique

scientific article

Long-term management of chronic heart failure patients in internal medicine

scientific article published on 18 January 2019

Long-term ursodeoxycholate improves circulating redox changes in primary biliary cirrhotic patients

scientific article published on 21 September 2011

Loss-of-Function of the Voltage-Gated Sodium Channel NaV1.5 (Channelopathies) in Patients With Irritable Bowel Syndrome

scientific article (publication date: June 2014)

Low membrane protein sulfhydrils but not G6PD deficiency predict ribavirin-induced hemolysis in hepatitis C.

scientific article

Management of chronic liver disease by general practitioners in southern Italy: unmet educational needs

scientific article published on 25 May 2011

Management of liver cirrhosis between primary care and specialists

scientific article published on May 2011

Measurements of gallbladder motor function by ultrasonography: towards standardization.

scientific article published in July 2003

Mechanisms of the Epithelial-Mesenchymal Transition and Tumor Microenvironment in Helicobacter pylori-Induced Gastric Cancer

scientific article published on 23 April 2020

Medicinal treatments of cholesterol gallstones: old, current and new perspectives

scientific article published on January 2009

Methodology and indications of H2-breath testing in gastrointestinal diseases: the Rome Consensus Conference.

scientific article published on March 2009

Micellar lipid composition profoundly affects LXR-dependent cholesterol transport across CaCo2 cells.

scientific article published on 20 March 2009

Microbiota in health and irritable bowel syndrome: current knowledge, perspectives and therapeutic options.

scientific article

Mitochondria in chronic liver disease.

scientific article published on June 2011

Mitochondrial dysfunction in rat with nonalcoholic fatty liver Involvement of complex I, reactive oxygen species and cardiolipin

scientific article

Mitochondrial glutathione content determines the rate of liver regeneration after partial hepatectomy in eu- and hypothyroid rats.

scientific article published in October 2003

Mitochondrial oxidative damage and myocardial fibrosis in rats chronically intoxicated with moderate doses of ethanol

scientific article published in September 2001

Modifiable Factors and Genetic Predisposition Associated with Gallbladder Cancer. A Concise Review

scientific article published in September 2015

Modulation of cholesterol crystallization in bile. Implications for non-surgical treatment of cholesterol gallstone disease.

scientific article

Modulation of hepatic redox status and mitochondrial metabolism by exercise: therapeutic strategy for liver diseases

scientific article published on 21 July 2013

Molecular Mechanisms of NAFLD in Metabolic Syndrome.

scientific article published on 20 May 2015

Molecular pathophysiology and physical chemistry of cholesterol gallstones

scientific article published on January 2008

Mutual changes of thioredoxin and nitrosothiols during biliary cirrhosis: results from humans and cholestatic rats

scientific article published on 01 February 2007

New insights into the molecular mechanism of intestinal fatty acid absorption

scientific article published on 18 September 2013

New insights into the molecular mechanisms underlying effects of estrogen on cholesterol gallstone formation.

scientific article published on 06 July 2009

Non-alcoholic fatty liver disease in the metabolic syndrome.

scientific article published on January 2007

Nonalcoholic fatty liver disease

scientific article published on 01 October 2010

Nonalcoholic steatohepatitis: recent advances from experimental models to clinical management.

scientific article

Noncommunicable diseases, climate change and iniquities: What COVID‐19 has taught us about syndemic

scientific article published in 2021

Novel Insights into the Pathogenesis and Management of the Metabolic Syndrome

scientific article published on 08 May 2020

Novel therapeutics for the treatment of familial Mediterranean fever: from colchicine to biologics

scientific article published on 18 July 2013

Obesity and the risk and prognosis of gallstone disease and pancreatitis

scientific article published on 22 July 2014

Obesity phenotypes and their paradoxical association with cardiovascular diseases

scientific article

Oxidative stress in symptom-free HCV carriers: relation with ALT flare-up.

scientific article

Oxidative stress-induced risk factors associated with the metabolic syndrome: a unifying hypothesis.

scientific article published on 12 September 2007

Oxidized LDL receptor 1 gene polymorphism in patients with metabolic syndrome

scientific article published on 7 November 2012

PNPLA3-associated steatohepatitis: toward a gene-based classification of fatty liver disease

scientific article

Parallel intestinal and liver injury during early cholestasis in the rat: modulation by bile salts and antioxidants

scientific article published on 30 January 2007

Pathogenic role of oxidative and nitrosative stress in primary biliary cirrhosis

scientific article

Pathways of cholesterol crystallization in model bile and native bile.

scientific article

Physical exercise antagonizes clinical and anatomical features characterizing Lieber-DeCarli diet-induced obesity and related metabolic disorders.

scientific article published on 3 April 2014

Prevention of cholesterol gallstones by inhibiting hepatic biosynthesis and intestinal absorption of cholesterol.

scientific article published on 19 February 2013

Randomised clinical trial: mesalazine and/or probiotics in maintaining remission of symptomatic uncomplicated diverticular disease--a double-blind, randomised, placebo-controlled study

scientific article published on 19 August 2013

Re-wiring the circuit: mitochondria as a pharmacological target in liver disease.

scientific article published on January 2011

Red blood cells (RBC) deformability and aggregability: alterations in alcoholism.

scientific article published in January 2006

Regulation of Cholesterol Metabolism by Bioactive Components of Soy Proteins: Novel Translational Evidence

scientific article published on 28 December 2020

Relationship between Liver Stiffness and Steatosis in Obesity Conditions: In Vivo and In Vitro Studies

scientific article published on 23 May 2022

Ribavirin-induced anemia: mechanisms, risk factors and related targets for future research.

scientific article published on January 2006

Role of mitochondria in nonalcoholic fatty liver disease--from origin to propagation.

scientific article published on 28 March 2012

Severe impairment of postprandial cholecystokinin release and gall-bladder emptying and high risk of gallstone formation in acromegalic patients during Sandostatin LAR.

scientific article

Severe liver steatosis correlates with nitrosative and oxidative stress in rats

scientific journal article

Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: A randomized controlled trial

scientific article published on 15 February 2012

Slow-transit constipation: solitary symptom of a systemic gastrointestinal disease.

scientific article published in February 1999

Sourdough Fermented Breads are More Digestible than Those Started with Baker's Yeast Alone: An In Vivo Challenge Dissecting Distinct Gastrointestinal Responses

scientific article published on 04 December 2019

Sphingomyelin protects against apoptosis and hyperproliferation induced by deoxycholate: potential implications for colon cancer.

scientific article

Steatosis in the liver.

scientific article published on October 2013

T16189C mitochondrial DNA variant is associated with metabolic syndrome in Caucasian subjects.

scientific article

Targeting the liver in the metabolic syndrome: evidence from animal models.

scientific article published on January 2007

Targets for current pharmacologic therapy in cholesterol gallstone disease

scientific article

Taurodeoxycholate-induced intestinal injury is modulated by oxidative stress-dependent pre-conditioning like mechanisms

scientific article

The Controversial Role of Human Gut Lachnospiraceae

scientific article published on 15 April 2020

The Relationship between Prebiotic Supplementation and Anthropometric and Biochemical Parameters in Patients with NAFLD-A Systematic Review and Meta-Analysis of Randomized Controlled Trials

scientific article published on 11 November 2020

The Vibrio cholerae cytolysin promotes chloride secretion from intact human intestinal mucosa

scientific article

The deletion of the estrogen receptor α gene reduces susceptibility to estrogen-induced cholesterol cholelithiasis in female mice

scientific article published on 29 July 2015

The dyspeptic syndrome in migraine: morphofunctional evaluation on 53 patients

scientific article published on 01 July 1996

The grandfather's fever

scientific article published on 10 August 2019

The impact of single parathyroid gland autotransplantation during thyroid surgery on postoperative hypoparathyroidism: a multicenter study

scientific article published on 01 January 2007

The inulin hydrogen breath test predicts the quality of colonic preparation

The two congested failing giants: heart and liver

scientific article published on 11 May 2019

Therapeutic reflections in cholesterol homeostasis and gallstone disease: a review

scientific article

Total thyroidectomy is improved by loupe magnification.

scientific article published in January 2004

Ursodeoxycholic acid reduces protein levels and nucleation-promoting activity in human gallbladder bile

scientific article published on 01 April 1996

Water channel proteins in bile formation and flow in health and disease: when immiscible becomes miscible.

scientific article published on 07 April 2012

Water handling and aquaporins in bile formation: recent advances and research trends

scientific article published on November 2003

Water transport into bile and role in bile formation

scientific article

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