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List of works by Alessandro Giuffrè

A Clinically Relevant Variant of the Human Hydrogen Sulfide-Synthesizing Enzyme Cystathionine β-Synthase: Increased CO Reactivity as a Novel Molecular Mechanism of Pathogenicity?

scientific article published on 22 March 2017

A Sulfite Respiration Pathway from Thermus thermophilus and the Key Role of Newly Identified Cytochrome c 550

scientific article published on June 10, 2011

A novel type of nitric-oxide reductase. Escherichia coli flavorubredoxin

scientific article

Antigiardial activity of novel triazolyl-quinolone-based chalcone derivatives: when oxygen makes the difference.

scientific article

Bioenergetic relevance of hydrogen sulfide and the interplay between gasotransmitters at human cystathionine β-synthase.

scientific article published on 30 March 2016

Catalytic intermediates of cytochrome bd terminal oxidase at steady-state: ferryl and oxy-ferrous species dominate

scientific article published on 23 February 2011

Chloride Bound to Oxidized CytochromecOxidase Controls the Reaction with Nitric Oxide

scientific article published in Journal of Biological Chemistry

Control of cytochrome c oxidase activity by nitric oxide

scientific article published on April 2004

Control of respiration by cytochrome c oxidase in intact cells: role of the membrane potential

scientific article published on 23 September 2009

Control of respiration by nitric oxide in Keilin-Hartree particles, mitochondria and SH-SY5Y neuroblastoma cells.

scientific article published in August 2003

Cytochrome bd Protects Bacteria against Oxidative and Nitrosative Stress: A Potential Target for Next-Generation Antimicrobial Agents

scientific article

Cytochrome bd and Gaseous Ligands in Bacterial Physiology

scientific article published on 10 July 2017

Cytochrome bd from Escherichia coli catalyzes peroxynitrite decomposition.

scientific article

Cytochrome bd oxidase and bacterial tolerance to oxidative and nitrosative stress

scientific article published on 31 January 2014

Cytochrome bd oxidase and hydrogen peroxide resistance in Mycobacterium tuberculosis.

scientific article published on 17 December 2013

Cytochrome bd oxidase and nitric oxide: from reaction mechanisms to bacterial physiology.

scientific article published on 03 August 2011

Cytochrome bd oxidase from Escherichia coli displays high catalase activity: an additional defense against oxidative stress.

scientific article published on 30 May 2013

Cytochrome bo3 from Escherichia coli: the binding and turnover of nitric oxide

scientific article published on 01 September 2002

Cytochrome c Oxidase Does Not Catalyze the Anaerobic Reduction of NO

scientific article published in 1998

Cytochrome c oxidase and nitric oxide in action: molecular mechanisms and pathophysiological implications.

scientific article published on 14 September 2011

Cytochrome c oxidase, ligands and electrons

scientific article

Electron transfer and ligand binding in terminal oxidases Impact of recent structural information

scientific article published on 01 August 1994

Electron transfer kinetics of caa3 oxidase from Bacillus stearothermophilus: a hypothesis for thermophilicity

scientific article

Engineering the internal cavity of neuroglobin demonstrates the role of the haem-sliding mechanism

scientific article

Evidence for Detrimental Cross Interactions between Reactive Oxygen and Nitrogen Species in Leber's Hereditary Optic Neuropathy Cells.

scientific article published on 31 December 2015

Failure of apoptosis-inducing factor to act as neuroglobin reductase

scientific article published on 24 September 2009

Flavodiiron oxygen reductase from Entamoeba histolytica: modulation of substrate preference by tyrosine 271 and lysine 53.

scientific article published on 23 August 2014

Flavohemoglobin and nitric oxide detoxification in the human protozoan parasite Giardia intestinalis.

scientific article published on 5 August 2010

Functional characterization of peroxiredoxins from the human protozoan parasite Giardia intestinalis

scientific article (publication date: 2014)

Functional dissection of the multi-domain di-heme cytochrome c(550) from Thermus thermophilus

scientific article

Giardia intestinalis escapes oxidative stress by colonizing the small intestine: A molecular hypothesis

Hydrogen Sulfide Biochemistry and Interplay with Other Gaseous Mediators in Mammalian Physiology

scientific article published on 27 June 2018

Hydrogen Sulfide Metabolism and Signaling in the Tumor Microenvironment

scientific article published on 01 January 2020

Hydrogen Sulfide Oxidation: Adaptive Changes in Mitochondria of SW480 Colorectal Cancer Cells upon Exposure to Hypoxia

scientific article published on 29 January 2019

In the respiratory chain of Escherichia coli cytochromes bd-I and bd-II are more sensitive to carbon monoxide inhibition than cytochrome bo3

scientific article published on 04 November 2019

Interaction of the bacterial terminal oxidase cytochrome bd with nitric oxide.

scientific article

Internal Electron Transfer in Cu-Heme Oxidases

scientific article published in Journal of Biological Chemistry

Investigating the mechanism of electron transfer to the binuclear center in Cu-heme oxidases

scientific article published in February 1998

Is neuroglobin a signal transducer?

Kinetic characterization of the Escherichia coli nitric oxide reductase flavorubredoxin

scientific article published on January 2008

Kinetic properties of ba3 oxidase from Thermus thermophilus: effect of temperature

scientific article published in January 1999

Kinetics of electron transfer from NADH to the Escherichia coli nitric oxide reductase flavorubredoxin.

scientific article published on 20 December 2006

Mechanism of S-nitrosothiol formation and degradation mediated by copper ions

scientific article published on 01 October 1999

Mitochondria and nitric oxide: chemistry and pathophysiology

scientific article published on January 2012

N-Acetylcysteine Serves as Substrate of 3-Mercaptopyruvate Sulfurtransferase and Stimulates Sulfide Metabolism in Colon Cancer Cells

scientific article published on 04 August 2019

NO* binds human cystathionine β-synthase quickly and tightly

scientific article

Neuroglobin, nitric oxide, and oxygen: functional pathways and conformational changes

scientific article

Neuroglobin: enzymatic reduction and oxygen affinity

scientific article published on 14 January 2008

Nitric Oxide Does Not Inhibit but Is Metabolized by the Cytochrome bcc-aa3 Supercomplex

scientific article published on 12 November 2020

Nitric Oxide Reacts with the Single-electron Reduced Active Site of CytochromecOxidase

scientific article published in Journal of Biological Chemistry

Nitric Oxide and Cytochrome c Oxidase: Mechanisms of Inhibition and NO Degradation

scientific article published on 01 July 2000

Nitric oxide and cytochrome oxidase: reaction mechanisms from the enzyme to the cell

scientific article

Nitric oxide and mitochondrial complex IV.

scientific article published on October 2003

Nitric oxide and the respiratory enzyme

scientific article published on 13 May 2006

Nitric oxide reacts with the ferryl-oxo catalytic intermediate of the CuB-lacking cytochrome bd terminal oxidase.

scientific article

Nitric oxide, cytochromecoxidase and myoglobin: Competition and reaction pathways

article

Nitrosative stress defences of the enterohepatic pathogenic bacterium Helicobacter pullorum

scientific article published on 30 August 2017

O(2)-dependent efficacy of novel piperidine- and piperazine-based chalcones against the human parasite Giardia intestinalis.

scientific article

On the Mechanism of Inhibition of CytochromecOxidase by Nitric Oxide

scientific article published in Journal of Biological Chemistry

Probing the access of protons to the K pathway in the Paracoccus denitrificans cytochrome c oxidase

scientific article published in January 2005

Proton uptake upon anaerobic reduction of the Paracoccus denitrificans cytochrome c oxidase: a kinetic investigation of the K354M and D124N mutants

scientific article published in March 2004

Reaction of Nitric Oxide with the Turnover Intermediates of CytochromecOxidase: Reaction Pathway and Functional Effects†

scientific article published on 01 December 2000

Reaction of nitric oxide with the oxidized di-heme and heme-copper oxygen-reducing centers of terminal oxidases: Different reaction pathways and end-products

scientific article published on 18 June 2009

Redox control of fast ligand dissociation from Escherichia coli cytochrome bd.

scientific article published on 30 January 2007

Redox properties of the oxygen-detoxifying flavodiiron protein from the human parasite Giardia intestinalis

scientific article published on 21 June 2009

Redox-linked protonation of cytochrome c oxidase: the effect of chloride bound to CuB.

scientific article published in October 2002

S-Adenosyl-l-methionine Modulates CO and NO• Binding to the Human H2S-generating Enzyme Cystathionine β-Synthase

scientific article

Screening Pyridine Derivatives against Human Hydrogen Sulfide-synthesizing Enzymes by Orthogonal Methods

scientific article published in Scientific Reports

Substrate-induced conformational change in cytochrome P450 OleP

scientific article published on 12 September 2018

Superoxide reductase from Giardia intestinalis: structural characterization of the first SOR from a eukaryotic organism shows an iron centre that is highly sensitive to photoreduction

scientific article

The Chemical Interplay between Nitric Oxide and Mitochondrial CytochromecOxidase: Reactions, Effectors and Pathophysiology

scientific article published on January 1, 2012

The O2-scavenging flavodiiron protein in the human parasite Giardia intestinalis

scientific article

The Terminal Oxidase Cytochrome bd Promotes Sulfide-resistant Bacterial Respiration and Growth.

scientific article published on 31 March 2016

The cytochrome cbb3 from Pseudomonas stutzeri displays nitric oxide reductase activity

scientific article published in December 2001

The presence of glutamate residues on the PAS sequence of the stimuli-sensitive nano-ferritin improves in vivo biodistribution and mitoxantrone encapsulation homogeneity

scientific article published on 20 February 2018

The superoxide reductase from the early diverging eukaryote Giardia intestinalis

scientific article published in October 2011

Trichomonas vaginalis degrades nitric oxide and expresses a flavorubredoxin-like protein: a new pathogenic mechanism?

scientific article published in March 2004