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List of works by Benjamin M. Segal

A new neutrophil subset promotes CNS neuron survival and axon regeneration

scientific article published on 26 October 2020

A randomized, subject and rater-blinded, placebo-controlled trial of dimethyl fumarate for obstructive sleep apnea

scientific article published on 01 August 2018

Americas Committee for Treatment and Research in Multiple Sclerosis Forum 2017: Environmental factors, genetics, and epigenetics in MS susceptibility and clinical course.

scientific article published in January 2018

An IFNγ/CXCL2 regulatory pathway determines lesion localization during EAE

scientific article published on 16 July 2018

An emerging role for eotaxins in neurodegenerative disease.

scientific article published on 21 September 2016

An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease.

scientific article

Antibodies to the RNA-binding protein hnRNP A1 contribute to neurodegeneration in a model of central nervous system autoimmune inflammatory disease.

scientific article published on 08 July 2016

B-cell targeting agents in the treatment of multiple sclerosis.

scientific article

CD4+ T Cells Orchestrate Lethal Immune Pathology despite Fungal Clearance during Cryptococcus neoformans Meningoencephalitis.

scientific article published on 21 November 2017

CNS-resident classical DCs play a critical role in CNS autoimmune disease

scientific article published on 29 October 2018

CXCL13 promotes isotype-switched B cell accumulation to the central nervous system during viral encephalomyelitis

scientific article published on 18 January 2016

Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease.

scientific article published on 05 February 2009

Clinical trials in multiple sclerosis: potential future trial designs

scientific article published on 13 May 2019

Differences in diffusion tensor imaging-derived metrics in the corpus callosum of patients with multiple sclerosis without and with gadolinium-enhancing cerebral lesions

scientific article published in July 2012

Dysregulation of the IL-23/IL-17 axis and myeloid factors in secondary progressive MS.

scientific article

Enhancing natural killer cells is beneficial in multiple sclerosis - Commentary

scientific article published on 13 November 2018

Experimental autoimmune encephalomyelitis

scientific article published on 01 January 2004

GM-CSF Promotes Chronic Disability in Experimental Autoimmune Encephalomyelitis by Altering the Composition of Central Nervous System-Infiltrating Cells, but Is Dispensable for Disease Induction

scientific article published on 29 December 2017

GM-CSF-dependent, CD103+ dermal dendritic cells play a critical role in Th effector cell differentiation after subcutaneous immunization.

scientific article

Getting to the crux of the matter: IL-23 and Th17 cell accumulation in the CNS.

scientific article published on July 2009

Highly polarized Th17 cells induce EAE via a T-bet independent mechanism

scientific article published on 23 August 2013

Hypnotic use and fatigue in multiple sclerosis.

scientific article published on 28 September 2014

IL-12 dependent/IFN gamma independent expression of CCR5 by myelin-reactive T cells correlates with encephalitogenicity

scientific article published on 01 April 2003

IL-12 driven upregulation of P-selectin ligand on myelin-specific T cells is a critical step in an animal model of autoimmune demyelination

scientific article published on 18 January 2006

IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition.

scientific article published on 23 June 2008

IL-12-polarized Th1 cells produce GM-CSF and induce EAE independent of IL-23.

scientific article published on 29 July 2015

IL-23 modulated myelin-specific T cells induce EAE via an IFNγ driven, IL-17 independent pathway ⬇️

scientific article published on October 15, 2010

In vitro polarization of T-helper cells

scientific article published on 01 January 2014

Increased rejection of primary tumors in mice lacking B cells: inhibition of anti-tumor CTL and TH1 cytokine responses by B cells

scientific article

MAdCAM-1-Mediated Intestinal Lymphocyte Homing Is Critical for the Development of Active Experimental Autoimmune Encephalomyelitis

article

Modulation of the Innate Immune System: A Future Approach to the Treatment of Neurological Disease

scientific article published on 01 April 2018

Multiple sclerosis relapse risk in the postoperative period: Effects of invasive surgery and anesthesia

scientific article published on 25 June 2019

Myeloid cell plasticity in the evolution of central nervous system autoimmunity

scientific article

Natalizumab (Tysabri) ⬇️

scientific article published on 05 August 2010

Neuroinflammation triggered by β-glucan/dectin-1 signaling enables CNS axon regeneration

scientific article

Neurosarcoidosis: diagnostic approaches and therapeutic strategies.

scientific article published on June 2013

Neutrophil-related factors as biomarkers in EAE and MS.

scientific article

Neutrophils promote VLA-4-dependent B cell antigen presentation and accumulation within the meninges during neuroinflammation

scientific article published on 07 November 2019

Notch signaling regulates T cell accumulation and function in the central nervous system during experimental autoimmune encephalomyelitis.

scientific article published on 03 July 2013

Obstructive sleep apnea and fatigue in patients with multiple sclerosis.

scientific article published on 15 February 2014

Obstructive sleep apnea is an under-recognized and consequential morbidity in multiple sclerosis

scientific article published on 15 June 2014

Primary progressive multiple sclerosis--why we are failing

scientific article published on 28 January 2016

Progressive decline in fractional anisotropy on serial DTI examinations of the corpus callosum: a putative marker of disease activity and progression in SPMS

scientific article published on 13 May 2011

Site-specific chemokine expression regulates central nervous system inflammation and determines clinical phenotype in autoimmune encephalomyelitis

scientific article

Stable biomarker for plastic microglia

scientific article published on 10 March 2016

Stage-specific immune dysregulation in multiple sclerosis

scientific article

Sublime diagnosis of Lyme neuroborreliosis

scientific article published on 01 August 2005

T-bet promotes the accumulation of encephalitogenic Th17 cells in the CNS.

scientific article published on 24 May 2016

TH17 cytokines in autoimmune neuro-inflammation ⬇️

scientific article published on 09 September 2011

Th Cell Diversity in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis

scientific article

Th1-mediated experimental autoimmune encephalomyelitis is CXCR3 independent

scientific article published on 21 August 2013

Th17 and Th1 responses directed against the immunizing epitope, as opposed to secondary epitopes, dominate the autoimmune repertoire during relapses of experimental autoimmune encephalomyelitis

scientific article published in June 2007

Th17 cells in autoimmune demyelinating disease.

scientific article

The Diversity of Encephalitogenic CD4+ T Cells in Multiple Sclerosis and Its Animal Models

scientific article published on 19 January 2019

The Th17-ELR+ CXC chemokine pathway is essential for the development of central nervous system autoimmune disease

scientific article published on 17 March 2008

The comeback of the elusive "suppressor" cell: an update on the regulatory network in EAE

scientific article published on 01 November 1998

The critical role of IL-12 and the IL-12R beta 2 subunit in the generation of pathogenic autoreactive Th1 cells.

scientific article

The dual roles of immunity in ALS: injury overrides protection.

scientific article published on 26 February 2015

The landscape of myeloid and astrocyte phenotypes in acute multiple sclerosis lesions

scientific article published on 12 August 2019

The lymphoid chemokine, CXCL13, is dispensable for the initial recruitment of B cells to the acutely inflamed central nervous system ⬇️

scientific article published on October 8, 2010

The role of natural killer cells in curbing neuroinflammation

scientific article

The straight talk on immune deviation

scientific article

The unwavering commitment of regulatory T cells in the suppression of autoimmune encephalomyelitis: another aspect of immune privilege in the CNS

scientific article published on May 2012

Treatment of CNS sarcoidosis with infliximab and mycophenolate mofetil

scientific article

Treatment of neuromyelitis optica spectrum disorders

scientific article published on 01 May 2019

Underrecognition of sleep disorders in patients with multiple sclerosis

scientific article published on 15 January 2015

Virus-induced CD8+ T cells accelerate the onset of experimental autoimmune encephalomyelitis: implications for how viral infections might trigger multiple sclerosis exacerbations

scientific article published on 18 April 2013

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