List of works - Alain Charbit

A cluster of charged and aromatic residues in the C-terminal portion of maltoporin participates in sugar binding and uptake.

scientific article

A genetic system to elicit and monitor antipeptide antibodies without peptide synthesis.

scientific article published in February 1991

A homolog of Bacillus subtilis trigger factor in Listeria monocytogenes is involved in stress tolerance and bacterial virulence

scientific article

A hypermutator phenotype attenuates the virulence of Listeria monocytogenes in a mouse model

scientific article

A model of maltodextrin transport through the sugar-specific porin, LamB, based on deletion analysis.

scientific article published on October 1994

A new family of secreted toxins in pathogenic Neisseria species

scientific article

A novel receptor - ligand pathway for entry of Francisella tularensis in monocyte-like THP-1 cells: interaction between surface nucleolin and bacterial elongation factor Tu.

scientific article

A putative P-type ATPase required for virulence and resistance to haem toxicity in Listeria monocytogenes

scientific article

A splenic IgM memory subset with antibacterial specificities is sustained from persistent mucosal responses

article

A widespread family of polymorphic toxins encoded by temperate phages.

scientific article published on 29 August 2017

ActA is required for crossing of the fetoplacental barrier by Listeria monocytogenes

scientific article published on 21 November 2006

Adsorption of bacteriophage lambda on the LamB protein of Escherichia coli K-12: point mutations in gene J of lambda responsible for extended host range

scientific article

Antibacterial Toxins: Gram-Positive Bacteria Strike Back!

scientific article published on 21 November 2017

Antibody response to a foreign epitope expressed at the surface of recombinant bacteria: importance of the route of immunization

article

Asparagine assimilation is critical for intracellular replication and dissemination of Francisella

scientific article published on 8 November 2013

Bacterial vectors to target and/or purify polypeptides: their use in immunological studies.

scientific article published in January 1991

Bacteriophage lambda receptor site on the Escherichia coli K-12 LamB protein

scientific article

CD8 single-cell gene coexpression reveals three different effector types present at distinct phases of the immune response

scientific article

Capacity of ivanolysin O to replace listeriolysin O in phagosomal escape and in vivo survival of Listeria monocytogenes

scientific article published on 01 March 2003

Changes in proteome of the Δhfq strain derived from Francisella tularensis LVS correspond with its attenuated phenotype

scientific article published on 22 September 2014

Chronic Staphylococcus aureus Lung Infection Correlates With Proteogenomic and Metabolic Adaptations Leading to an Increased Intracellular Persistence

scientific article published on 01 November 2019

Cognate antigen stimulation generates potent CD8(+) inflammatory effector T cells

scientific article published on 16 December 2013

Construction and first characterization of two reciprocal hybrids between LamB from Escherichia coli K12 and Klebsiella pneumoniae.

scientific article

Contribution of the multiple Type I signal peptidases to the secretome of Listeria monocytogenes: deciphering their specificity for secreted exoproteins by exoproteomic analysis

scientific article published on 28 January 2015

Coordination of carbon and nitrogen metabolism.

scientific article published on July 1996

Creation of targets for proteolytic cleavage in the LamB protein of E coli K12 by genetic insertion of foreign sequences: implications for topological studies.

scientific article published in February 1990

Critical Role of a Sheath Phosphorylation Site On the Assembly and Function of an Atypical Type VI Secretion System

scientific article published on 02 October 2019

Critical role of neighbouring sequences on the immunogenicity of the C3 poliovirus neutralization epitope expressed at the surface of recombinant bacteria

scientific article published on 01 June 1990

Critical role of the N-terminal residues of listeriolysin O in phagosomal escape and virulence ofListeria monocytogenes

scientific article published on 01 October 2002

DNA sequence analysis of the lamB gene from Klebsiella pneumoniae: implications for the topology and the pore functions in maltoporin.

scientific article published in June 1992

Detection of the Interaction Between Host and Bacterial Proteins: Eukaryotic Nucleolin Interacts with Francisella Elongation Factor Tu

article published in 2014

Differential roles of multiple signal peptidases in the virulence of Listeria monocytogenes

scientific article published in March 2004

Exploring the role of the CTL epitope region of listeriolysin O in the pathogenesis of Listeria monocytogenes.

scientific article published in May 2006

Expression and immune response to foreign epitopes in bacteria. Perspectives for live vaccine development

scientific article published in February 1997

Expression and immunogenicity of the V3 loop from the envelope of human immunodeficiency virus type 1 in an attenuated aroA strain of Salmonella typhimurium upon genetic coupling to two Escherichia coli carrier proteins

scientific article published in September 1993

Expression of Human β1 and β2 Adrenergic Receptors in E. Coli As a New Tool for Ligand Screening

scholarly article by Stefano Marullo et al published September 1989 in Nature Biotechnology

Expression of a poliovirus neutralization epitope at the surface of recombinant bacteria: first immunization results.

scientific article

Francisella tularensis IglG Belongs to a Novel Family of PAAR-Like T6SS Proteins and Harbors a Unique N-terminal Extension Required for Virulence

scientific article (publication date: September 2016)

Francisella tularensis intracellular survival: To eat or to die.

scientific article published on 25 October 2013

Francisella tularensis metabolism and its relation to virulence

scientific article

Francisella tularensis regulates the expression of the amino acid transporter SLC1A5 in infected THP-1 human monocytes

scientific article

Fulminant arterial vasculitis as an unusual complication of disseminated staphylococcal disease due to the emerging CC1 methicillin-susceptible Staphylococcus aureus clone: a case report

scientific article published on 03 April 2019

Function of the duplicated IIB domain and oligomeric structure of the fructose permease of Escherichia coli.

scientific article

Functional assembly of two membrane-binding domains in listeriolysin O, the cytolysin of Listeria monocytogenes

scientific article published on 01 October 2001

Further genetic analysis of the C-terminal external loop region in Escherichia coli maltoporin.

scientific article published on June 1997

Further sequence analysis of the phage lambda receptor site. Possible implications for the organization of the lamB protein in Escherichia coli K12.

scientific article

Genetic Manipulations

article published in 2008

Gluconeogenesis, an essential metabolic pathway for pathogenic Francisella

scientific article published on 20 July 2015

Glutamate utilization couples oxidative stress defense and the tricarboxylic acid cycle in Francisella phagosomal escape

scientific article published on 16 January 2014

Glutathione provides a source of cysteine essential for intracellular multiplication of Francisella tularensis

scientific article

Hfq, a novel pleiotropic regulator of virulence-associated genes in Francisella tularensis

scientific article published on 17 February 2009

High efficiency transformation of Salmonella typhimurium and Salmonella typhi by electroporation

scientific article published in August 1990

Horizontal transfer of chromosomal DNA between the marine bacterium Vibrio furnissii and Escherichia coli revealed by sequence analysis

scientific article

Host glycosylation pathways and the unfolded protein response contribute to the infection by Francisella

scientific article published on 17 May 2016

Identification of LpeA, a PsaA-like membrane protein that promotes cell entry by Listeria monocytogenes

scientific article

Identification of a PEST-like motif in listeriolysin O required for phagosomal escape and for virulence in Listeria monocytogenes

scientific article published on 01 March 2001

Identification of a cryptic porin gene in the Escherichia coli genome: expression and insertion of a monomeric form of the protein into the outer membrane

article

Identification of a novel small RNA modulating Francisella tularensis pathogenicity

scientific article

Identification of a putative chaperone involved in stress resistance and virulence in Francisella tularensis

scientific article

Identification of an essential gene of Listeria monocytogenes involved in teichoic acid biogenesis

scientific article

Identification of new genes involved in the virulence of Listeria monocytogenes by signature-tagged transposon mutagenesis.

scientific article

Identification of small RNAs in Francisella tularensis

scientific article

Identification of the agr locus of Listeria monocytogenes: role in bacterial virulence

scientific article

Identification of trkH, encoding a potassium uptake protein required for Francisella tularensis systemic dissemination in mice

scientific article

Immune responses to hybrid maltose-binding proteins

scientific article published in January 1993

Immunodominance of a recombinant T-cell epitope depends on its molecular environment

scientific article published on 01 December 1993

Immunogenicity of foreign peptide epitopes expressed in bacterial envelope proteins

scientific article published in September 1990

Immunogenicity of recombinant hybrid proteins in attenuated Salmonella typhimurium

scientific article published in 1992

Immunogenicity of viral B- and T-cell epitopes expressed in recombinant bacterial proteins.

scientific article

Immunogenicity of viral B-cell epitopes inserted into two surface loops of the Escherichia coli K12 LamB protein and expressed in an attenuated aroA strain of Salmonella typhimurium

scientific article published in January 1999

Importance of Metabolic Adaptations in Francisella Pathogenesis

scientific article published on 28 March 2017

Importance of branched-chain amino acid utilization in Francisella intracellular adaptation

scientific article

Importance of host cell arginine uptake in Francisella phagosomal escape and ribosomal protein amounts

scientific article

In vivo and in vitro studies of major surface loop deletion mutants of the Escherichia coli K-12 maltoporin: contribution to maltose and maltooligosaccharide transport and binding.

scientific article

Interaction of bacteriophage lambda with its cell surface receptor: an in vitro study of binding of the viral tail protein gpJ to LamB (Maltoporin).

scientific article published on February 2006

Intracellular Survival of Staphylococcus aureus in Endothelial Cells: A Matter of Growth or Persistence

scientific article

Intradermal Immunization with rAAV1 Vector Induces Robust Memory CD8(+) T Cell Responses Independently of Transgene Expression in DCs.

scientific article

Iron acquisition systems for ferric hydroxamates, haemin and haemoglobin in Listeria monocytogenes

scientific article published in February 2006

Is there a neutralization epitope in the second conserved domain of HIV-1 envelope protein?

scientific article

Isolation of Plasmids

Lessons from signature-tagged mutagenesis on the infectious mechanisms of pathogenic bacteria

scientific article

Listeriolysin O: a key protein of Listeria monocytogenes with multiple functions

scientific article published on July 2006

Localization and characterization of three different beta-adrenergic receptors expressed in Escherichia coli

scientific article published in January 1990

Loops and networks in control of Francisella tularensis virulence

scientific article published on August 2009

Maltodextrin transport through LamB

scientific article published on May 1, 2003

Manipulation of host membranes by the bacterial pathogens Listeria, Francisella, Shigella and Yersinia

scientific article

Maturation of lipoproteins by type II signal peptidase is required for phagosomal escape of Listeria monocytogenes

scientific article

Mechanisms of iron and haem transport by Listeria monocytogenes

scientific article published on May 2012

Modification of the signal sequence cleavage site of listeriolysin O does not affect protein secretion but impairs the virulence of Listeria monocytogenes

scientific article published on 01 May 2003

Molecular and cellular parameters controlling the immunogenicity of foreign B- or T-cell epitopes expressed by recombinant vectors.

scientific article

Molecular and cellular targeting in the expression of foreign polypeptides in bacteria

scientific article published in February 1992

Multitasking Actors of Staphylococcus aureus Metabolism and Virulence

scientific article published on 18 November 2019

Mutagenesis by random linker insertion into the lamB gene of Escherichia coli K12

article

Nanopores: maltoporin channel as a sensor for maltodextrin and lambda-phage

scientific article

Novel phosphotransferase genes revealed by bacterial genome sequencing: a gene cluster encoding a putative N-acetylgalactosamine metabolic pathway in Escherichia coli

scientific article

Nucleolin, a shuttle protein promoting infection of human monocytes by Francisella tularensis

scientific article

PH-induced collapse of the extracellular loops closes Escherichia coli maltoporin and allows the study of asymmetric sugar binding

scientific article

Pathogenesis of Francisella tularensis in Humans

Permissive sites and topology of an outer membrane protein with a reporter epitope ⬇️

scientific article published on January 1, 1991

Pivotal Role of Mitochondria in Macrophage Response to Bacterial Pathogens

scientific article published on 23 October 2019

Pivotal role of the Francisella tularensis heat-shock sigma factor RpoH.

scientific article

Possible links between stress defense and the tricarboxylic acid (TCA) cycle in Francisella pathogenesis

scientific article published on 13 May 2013

Presentation of two epitopes of the preS2 region of hepatitis B virus on live recombinant bacteria

scientific article published in September 1987

Probing the topology of a bacterial membrane protein by genetic insertion of a foreign epitope; expression at the cell surface.

scientific article published on November 1986

Proteins involved in Francisella tularensis survival and replication inside macrophages

scientific article

Reactive Oxygen Species-Dependent Innate Immune Mechanisms Control Methicillin-Resistant Staphylococcus aureus Virulence in the <i>Drosophila</i> Larval Model

scientific article published on 15 June 2021

Regulation of expression of type I signal peptidases in Listeria monocytogenes

scientific article published in November 2005

Regulation of virulence in Francisella tularensis by small non-coding RNAs

Role of FliF and FliI of Listeria monocytogenes in Flagellar Assembly and Pathogenicity

scientific article published in 2007

Role of FliF and FliI of Listeria monocytogenes in flagellar assembly and pathogenicity

scientific article

Role of Glycosylation/Deglycolysation Processes in Francisella tularensis Pathogenesis

scientific article published on 21 March 2017

Role of the wbt locus of Francisella tularensis in lipopolysaccharide O-antigen biogenesis and pathogenicity

scientific article published on 9 October 2006

Sortase B, a new class of sortase in Listeria monocytogenes

scientific article

Sortase independent and dependent systems for acquisition of haem and haemoglobin in Listeria monocytogenes

scientific article

Studies of the anaerobically induced promoter pnirB and the improved expression of bacterial antigens

scientific article published in March 1995

The Maltose B Region in Salmonella Typhimurium, Escherichia Coli and Other Enterobacteriaceae

scholarly article published 1993

The absence of N-acetylglucosamine in wall teichoic acids of Listeria monocytogenes modifies biofilm architecture and tolerance to rinsing and cleaning procedures

scientific article published on 10 January 2018

The complex amino acid diet of Francisella in infected macrophages

scientific article

The heat-shock protein ClpB of Francisella tularensis is involved in stress tolerance and is required for multiplication in target organs of infected mice.

scientific article

The metabolic enzyme fructose-1,6-bisphosphate aldolase acts as a transcriptional regulator in pathogenic Francisella

scientific article published on 11 October 2017

The sortase SrtA of Listeria monocytogenes is involved in processing of internalin and in virulence

scientific article

The svpA-srtB locus of Listeria monocytogenes: fur-mediated iron regulation and effect on virulence

scientific article

The unraveling panoply of Francisella tularensis virulence attributes

scientific article published on 23 December 2009

Transketolase of Staphylococcus aureus in the Control of Master Regulators of Stress Response During Infection

scientific article published on 01 November 2019

Versatility of a vector for expressing foreign polypeptides at the surface of Gram-negative bacteria

article

[A genetic method for exposing a given epitope at the surface of the bacterium Escherichia coli. Perspectives]

scientific article

lmo1273, a novel gene involved in Listeria monocytogenes virulence

scientific article

malM, a new gene of the maltose regulon in Escherichia coli K12. I. malM is the last gene of the malK-lamB operon and encodes a periplasmic protein

scientific article

List of works by Alain Charbit

A cluster of charged and aromatic residues in the C-terminal portion of maltoporin participates in sugar binding and uptake.

A genetic system to elicit and monitor antipeptide antibodies without peptide synthesis.

A homolog of Bacillus subtilis trigger factor in Listeria monocytogenes is involved in stress tolerance and bacterial virulence

A hypermutator phenotype attenuates the virulence of Listeria monocytogenes in a mouse model

A model of maltodextrin transport through the sugar-specific porin, LamB, based on deletion analysis.

A new family of secreted toxins in pathogenic Neisseria species

A novel receptor - ligand pathway for entry of Francisella tularensis in monocyte-like THP-1 cells: interaction between surface nucleolin and bacterial elongation factor Tu.

A putative P-type ATPase required for virulence and resistance to haem toxicity in Listeria monocytogenes

A splenic IgM memory subset with antibacterial specificities is sustained from persistent mucosal responses

A widespread family of polymorphic toxins encoded by temperate phages.

ActA is required for crossing of the fetoplacental barrier by Listeria monocytogenes

Adsorption of bacteriophage lambda on the LamB protein of Escherichia coli K-12: point mutations in gene J of lambda responsible for extended host range

Antibacterial Toxins: Gram-Positive Bacteria Strike Back!

Antibody response to a foreign epitope expressed at the surface of recombinant bacteria: importance of the route of immunization

Asparagine assimilation is critical for intracellular replication and dissemination of Francisella

Bacterial vectors to target and/or purify polypeptides: their use in immunological studies.

Bacteriophage lambda receptor site on the Escherichia coli K-12 LamB protein

CD8 single-cell gene coexpression reveals three different effector types present at distinct phases of the immune response

Capacity of ivanolysin O to replace listeriolysin O in phagosomal escape and in vivo survival of Listeria monocytogenes

Changes in proteome of the Δhfq strain derived from Francisella tularensis LVS correspond with its attenuated phenotype

Chronic Staphylococcus aureus Lung Infection Correlates With Proteogenomic and Metabolic Adaptations Leading to an Increased Intracellular Persistence

Cognate antigen stimulation generates potent CD8(+) inflammatory effector T cells

Construction and first characterization of two reciprocal hybrids between LamB from Escherichia coli K12 and Klebsiella pneumoniae.

Contribution of the multiple Type I signal peptidases to the secretome of Listeria monocytogenes: deciphering their specificity for secreted exoproteins by exoproteomic analysis

Coordination of carbon and nitrogen metabolism.

Creation of targets for proteolytic cleavage in the LamB protein of E coli K12 by genetic insertion of foreign sequences: implications for topological studies.

Critical Role of a Sheath Phosphorylation Site On the Assembly and Function of an Atypical Type VI Secretion System

Critical role of neighbouring sequences on the immunogenicity of the C3 poliovirus neutralization epitope expressed at the surface of recombinant bacteria

Critical role of the N-terminal residues of listeriolysin O in phagosomal escape and virulence ofListeria monocytogenes

DNA sequence analysis of the lamB gene from Klebsiella pneumoniae: implications for the topology and the pore functions in maltoporin.

Detection of the Interaction Between Host and Bacterial Proteins: Eukaryotic Nucleolin Interacts with Francisella Elongation Factor Tu

Differential roles of multiple signal peptidases in the virulence of Listeria monocytogenes

Exploring the role of the CTL epitope region of listeriolysin O in the pathogenesis of Listeria monocytogenes.

Expression and immune response to foreign epitopes in bacteria. Perspectives for live vaccine development

Expression and immunogenicity of the V3 loop from the envelope of human immunodeficiency virus type 1 in an attenuated aroA strain of Salmonella typhimurium upon genetic coupling to two Escherichia coli carrier proteins

Expression of Human β1 and β2 Adrenergic Receptors in E. Coli As a New Tool for Ligand Screening

Expression of a poliovirus neutralization epitope at the surface of recombinant bacteria: first immunization results.

Francisella tularensis IglG Belongs to a Novel Family of PAAR-Like T6SS Proteins and Harbors a Unique N-terminal Extension Required for Virulence

Francisella tularensis intracellular survival: To eat or to die.

Francisella tularensis metabolism and its relation to virulence

Francisella tularensis regulates the expression of the amino acid transporter SLC1A5 in infected THP-1 human monocytes

Fulminant arterial vasculitis as an unusual complication of disseminated staphylococcal disease due to the emerging CC1 methicillin-susceptible Staphylococcus aureus clone: a case report

Function of the duplicated IIB domain and oligomeric structure of the fructose permease of Escherichia coli.

Functional assembly of two membrane-binding domains in listeriolysin O, the cytolysin of Listeria monocytogenes

Further genetic analysis of the C-terminal external loop region in Escherichia coli maltoporin.

Further sequence analysis of the phage lambda receptor site. Possible implications for the organization of the lamB protein in Escherichia coli K12.

Genetic Manipulations

Gluconeogenesis, an essential metabolic pathway for pathogenic Francisella

Glutamate utilization couples oxidative stress defense and the tricarboxylic acid cycle in Francisella phagosomal escape

Glutathione provides a source of cysteine essential for intracellular multiplication of Francisella tularensis

Hfq, a novel pleiotropic regulator of virulence-associated genes in Francisella tularensis

High efficiency transformation of Salmonella typhimurium and Salmonella typhi by electroporation

Horizontal transfer of chromosomal DNA between the marine bacterium Vibrio furnissii and Escherichia coli revealed by sequence analysis

Host glycosylation pathways and the unfolded protein response contribute to the infection by Francisella

Identification of LpeA, a PsaA-like membrane protein that promotes cell entry by Listeria monocytogenes

Identification of a PEST-like motif in listeriolysin O required for phagosomal escape and for virulence in Listeria monocytogenes

Identification of a cryptic porin gene in the Escherichia coli genome: expression and insertion of a monomeric form of the protein into the outer membrane

Identification of a novel small RNA modulating Francisella tularensis pathogenicity

Identification of a putative chaperone involved in stress resistance and virulence in Francisella tularensis

Identification of an essential gene of Listeria monocytogenes involved in teichoic acid biogenesis

Identification of new genes involved in the virulence of Listeria monocytogenes by signature-tagged transposon mutagenesis.

Identification of small RNAs in Francisella tularensis

Identification of the agr locus of Listeria monocytogenes: role in bacterial virulence

Identification of trkH, encoding a potassium uptake protein required for Francisella tularensis systemic dissemination in mice

Immune responses to hybrid maltose-binding proteins

Immunodominance of a recombinant T-cell epitope depends on its molecular environment

Immunogenicity of foreign peptide epitopes expressed in bacterial envelope proteins

Immunogenicity of recombinant hybrid proteins in attenuated Salmonella typhimurium

Immunogenicity of viral B- and T-cell epitopes expressed in recombinant bacterial proteins.

Immunogenicity of viral B-cell epitopes inserted into two surface loops of the Escherichia coli K12 LamB protein and expressed in an attenuated aroA strain of Salmonella typhimurium

Importance of Metabolic Adaptations in Francisella Pathogenesis

Importance of branched-chain amino acid utilization in Francisella intracellular adaptation

Importance of host cell arginine uptake in Francisella phagosomal escape and ribosomal protein amounts

In vivo and in vitro studies of major surface loop deletion mutants of the Escherichia coli K-12 maltoporin: contribution to maltose and maltooligosaccharide transport and binding.

Interaction of bacteriophage lambda with its cell surface receptor: an in vitro study of binding of the viral tail protein gpJ to LamB (Maltoporin).

Intracellular Survival of Staphylococcus aureus in Endothelial Cells: A Matter of Growth or Persistence

Intradermal Immunization with rAAV1 Vector Induces Robust Memory CD8(+) T Cell Responses Independently of Transgene Expression in DCs.

Iron acquisition systems for ferric hydroxamates, haemin and haemoglobin in Listeria monocytogenes

Is there a neutralization epitope in the second conserved domain of HIV-1 envelope protein?