List of works - Anna Colell

A Functional Role of GAS6/TAM in Nonalcoholic Steatohepatitis Progression Implicates AXL as Therapeutic Target

scientific article published on 02 November 2019

APP/PS1 mice overexpressing SREBP-2 exhibit combined Aβ accumulation and tau pathology underlying Alzheimer's disease.

scientific article published on 06 May 2013

ASMase is required for chronic alcohol induced hepatic endoplasmic reticulum stress and mitochondrial cholesterol loading.

scientific article published on 23 May 2013

Acetaldehyde impairs mitochondrial glutathione transport in HepG2 cells through endoplasmic reticulum stress

scientific article

Acidic sphingomyelinase downregulates the liver-specific methionine adenosyltransferase 1A, contributing to tumor necrosis factor-induced lethal hepatitis

scientific article published on March 2004

Ageing and chronic intermittent hypoxia mimicking sleep apnea do not modify local brain tissue stiffness in healthy mice

scientific article

Alcohol, signaling, and ECM turnover.

scientific article published on 23 October 2009

Alcoholic liver injury and apoptosis--synopsis of the symposium held at ESBRA 2001: 8th Congress of the European Society for Biomedical Research on Alcoholism, Paris, September 16, 2001.

scientific article published in October 2002

Alzheimer's Disease Mutant Mice Exhibit Reduced Brain Tissue Stiffness Compared to Wild-type Mice in both Normoxia and following Intermittent Hypoxia Mimicking Sleep Apnea

scientific article published on 19 January 2018

Antiapoptotic BCL-2 proteins determine sorafenib/regorafenib resistance and BH3-mimetic efficacy in hepatocellular carcinoma.

scientific article published on 30 March 2018

Caveolin-1 deficiency causes cholesterol-dependent mitochondrial dysfunction and apoptotic susceptibility.

scientific article published on 14 April 2011

Ceramide generated by acidic sphingomyelinase contributes to tumor necrosis factor-α-mediated apoptosis in human colon HT-29 cells through glycosphingolipids formation

scientific article published on 01 August 2002

Ceramide, tumor necrosis factor and alcohol-induced liver disease

scientific article

Cholesterol alters mitophagy by impairing optineurin recruitment and lysosomal clearance in Alzheimer's disease

scientific article published on 08 March 2021

Cholesterol and peroxidized cardiolipin in mitochondrial membrane properties, permeabilization and cell death

scientific article

Cholesterol and sphingolipids in alcohol-induced liver injury

scientific article published on March 2008

Cholesterol impairs autophagy-mediated clearance of amyloid beta while promoting its secretion

scientific article published on 04 June 2018

Cholesterol impairs the adenine nucleotide translocator-mediated mitochondrial permeability transition through altered membrane fluidity

scientific journal article

Chronic Ethanol Feeding Induces Cellular Antioxidants Decrease and Oxidative Stress in Rat Peripheral Nerves. Effect of S-Adenosyl-l-Methionine and N-Acetyl-l-Cysteine

scientific article published on 01 August 1998

Critical role of mitochondrial glutathione in the survival of hepatocytes during hypoxia

scientific article

Cysteine cathepsins control hepatic NF-κB-dependent inflammation via sirtuin-1 regulation.

scientific article

Defective TNF-alpha-mediated hepatocellular apoptosis and liver damage in acidic sphingomyelinase knockout mice

scientific article

Defective TNF-α–mediated hepatocellular apoptosis and liver damage in acidic sphingomyelinase knockout mice

Differential Role of Cathepsins S and B In Hepatic APC-Mediated NKT Cell Activation and Cytokine Secretion.

scientific article

Differential role of ethanol and acetaldehyde in the induction of oxidative stress in HEP G2 cells: effect on transcription factors AP-1 and NF-kappaB

scientific article

Direct Effect of Ceramide on the Mitochondrial Electron Transport Chain Leads to Generation of Reactive Oxygen Species

scientific article published in Journal of Biological Chemistry

Direct interaction of GD3 ganglioside with mitochondria generates reactive oxygen species followed by mitochondrial permeability transition, cytochrome c release, and caspase activation

scientific article (publication date: May 2000)

Divergent role of ceramide generated by exogenous sphingomyelinases on NF-kappa B activation and apoptosis in human colon HT-29 cells.

scientific article published in August 2002

Endoplasmic reticulum stress mediates amyloid β neurotoxicity via mitochondrial cholesterol trafficking

scientific article

Evidence that the rat hepatic mitochondrial carrier is distinct from the sinusoidal and canalicular transporters for reduced glutathione. Expression studies in Xenopus laevis oocytes

scientific article published in July 1995

Feeding S-adenosyl-L-methionine attenuates both ethanol-induced depletion of mitochondrial glutathione and mitochondrial dysfunction in periportal and perivenous rat hepatocytes

scientific article published on January 1995

GAPDH and Autophagy Preserve Survival after Apoptotic Cytochrome c Release in the Absence of Caspase Activation

GAPDH and autophagy preserve survival after apoptotic cytochrome c release in the absence of caspase activation

scientific article published in June 2007

GSH transport in mitochondria: defense against TNF-induced oxidative stress and alcohol-induced defect.

scientific article published on July 1997

Ganglioside GD3 enhances apoptosis by suppressing the nuclear factor-kappa B-dependent survival pathway

Glycosphingolipids and mitochondria: role in apoptosis and disease.

scientific article published in January 2004

Hepatocarcinogenesis and ceramide/cholesterol metabolism

scientific article published on May 2012

How is the liver primed or sensitized for alcoholic liver disease?

scientific article published in May 2001

Human placenta sphingomyelinase, an exogenous acidic pH-optimum sphingomyelinase, induces oxidative stress, glutathione depletion, and apoptosis in rat hepatocytes

scientific article

Inhibition of rat sinusoidal GSH transporter by thioethers: specificity, sidedness, and kinetics

scientific article

Mechanism of mitochondrial glutathione-dependent hepatocellular susceptibility to TNF despite NF-kappaB activation.

scientific article

Metabolic therapy: lessons from liver diseases.

scientific article published on December 2011

Mitochondria, cholesterol and amyloid beta peptide: a dangerous trio in Alzheimer disease.

scientific article published on October 2009

Mitochondrial Glutathione: Importance and Transport

article

Mitochondrial Glutathione: Recent Insights and Role in Disease

scientific article published on 24 September 2020

Mitochondrial S-adenosyl-L-methionine transport is insensitive to alcohol-mediated changes in membrane dynamics.

scientific article published on 9 April 2009

Mitochondrial cholesterol accumulation in alcoholic liver disease: Role of ASMase and endoplasmic reticulum stress.

scientific article

Mitochondrial cholesterol contributes to chemotherapy resistance in hepatocellular carcinoma.

scientific article

Mitochondrial cholesterol in health and disease

scientific article published on January 2009

Mitochondrial cholesterol loading exacerbates amyloid beta peptide-induced inflammation and neurotoxicity

scientific article published on May 2009

Mitochondrial free cholesterol loading sensitizes to TNF- and Fas-mediated steatohepatitis

scientific article published on September 2006

Mitochondrial glutathione, a key survival antioxidant

scientific article

Mitochondrial glutathione: features, regulation and role in disease

scientific article

Mitochondrial permeability transition induced by reactive oxygen species is independent of cholesterol-regulated membrane fluidity

scientific article published in February 2004

Novel roles for GAPDH in cell death and carcinogenesis.

scientific article published on 25 September 2009

Oxidative stress and alcoholic liver disease.

scientific article

Oxidative stress and altered mitochondrial function in neurodegenerative diseases: lessons from mouse models

scientific article published on August 2010

Oxidative stress: role of mitochondria and protection by glutathione

scientific article published in January 1998

PGE1 protection against apoptosis induced by D-galactosamine is not related to the modulation of intracellular free radical production in primary culture of rat hepatocytes

scientific article published in March 2002

Recent Insights into the Mitochondrial Role in Autophagy and Its Regulation by Oxidative Stress

scientific article published on 04 November 2019

Redox control of liver function in health and disease

scientific article

Role of oxidative stress generated from the mitochondrial electron transport chain and mitochondrial glutathione status in loss of mitochondrial function and activation of transcription factor nuclear factor-kappa B: studies with isolated mitochondri

scientific article published on 01 November 1995

S-Adenosyl-L-methionine and mitochondrial reduced glutathione depletion in alcoholic liver disease

scientific article

Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor

scientific article published on 01 December 1998

Sensitivity of the 2-oxoglutarate carrier to alcohol intake contributes to mitochondrial glutathione depletion

scientific journal article

Targeting glucosylceramide synthase upregulation reverts sorafenib resistance in experimental hepatocellular carcinoma

scientific article published on 22 January 2016

Tauroursodeoxycholic acid protects hepatocytes from ethanol-fed rats against tumor necrosis factor-induced cell death by replenishing mitochondrial glutathione.

scientific article published in November 2001

Trafficking of ganglioside GD3 to mitochondria by tumor necrosis factor-alpha

scientific journal article

Transcriptional regulation of the heavy subunit chain of gamma-glutamylcysteine synthetase by ionizing radiation.

scientific article published in May 1998

Transport of reduced glutathione in hepatic mitochondria and mitoplasts from ethanol-treated rats: Effect of membrane physical properties andS-adenosyl-L-methionine

scientific article published on 01 September 1997

Tumor necrosis factor increases hepatocellular glutathione by transcriptional regulation of the heavy subunit chain of gamma-glutamylcysteine synthetase.

scientific article published on November 1997

List of works by Anna Colell

A Functional Role of GAS6/TAM in Nonalcoholic Steatohepatitis Progression Implicates AXL as Therapeutic Target

APP/PS1 mice overexpressing SREBP-2 exhibit combined Aβ accumulation and tau pathology underlying Alzheimer's disease.

ASMase is required for chronic alcohol induced hepatic endoplasmic reticulum stress and mitochondrial cholesterol loading.

Acetaldehyde impairs mitochondrial glutathione transport in HepG2 cells through endoplasmic reticulum stress

Acidic sphingomyelinase downregulates the liver-specific methionine adenosyltransferase 1A, contributing to tumor necrosis factor-induced lethal hepatitis

Ageing and chronic intermittent hypoxia mimicking sleep apnea do not modify local brain tissue stiffness in healthy mice

Alcohol, signaling, and ECM turnover.

Alcoholic liver injury and apoptosis--synopsis of the symposium held at ESBRA 2001: 8th Congress of the European Society for Biomedical Research on Alcoholism, Paris, September 16, 2001.

Alzheimer's Disease Mutant Mice Exhibit Reduced Brain Tissue Stiffness Compared to Wild-type Mice in both Normoxia and following Intermittent Hypoxia Mimicking Sleep Apnea

Antiapoptotic BCL-2 proteins determine sorafenib/regorafenib resistance and BH3-mimetic efficacy in hepatocellular carcinoma.

Caveolin-1 deficiency causes cholesterol-dependent mitochondrial dysfunction and apoptotic susceptibility.

Ceramide generated by acidic sphingomyelinase contributes to tumor necrosis factor-α-mediated apoptosis in human colon HT-29 cells through glycosphingolipids formation

Ceramide, tumor necrosis factor and alcohol-induced liver disease

Cholesterol alters mitophagy by impairing optineurin recruitment and lysosomal clearance in Alzheimer's disease

Cholesterol and peroxidized cardiolipin in mitochondrial membrane properties, permeabilization and cell death

Cholesterol and sphingolipids in alcohol-induced liver injury

Cholesterol impairs autophagy-mediated clearance of amyloid beta while promoting its secretion

Cholesterol impairs the adenine nucleotide translocator-mediated mitochondrial permeability transition through altered membrane fluidity

Chronic Ethanol Feeding Induces Cellular Antioxidants Decrease and Oxidative Stress in Rat Peripheral Nerves. Effect of S-Adenosyl-l-Methionine and N-Acetyl-l-Cysteine

Critical role of mitochondrial glutathione in the survival of hepatocytes during hypoxia

Cysteine cathepsins control hepatic NF-κB-dependent inflammation via sirtuin-1 regulation.

Defective TNF-alpha-mediated hepatocellular apoptosis and liver damage in acidic sphingomyelinase knockout mice

Defective TNF-α–mediated hepatocellular apoptosis and liver damage in acidic sphingomyelinase knockout mice

Differential Role of Cathepsins S and B In Hepatic APC-Mediated NKT Cell Activation and Cytokine Secretion.

Differential role of ethanol and acetaldehyde in the induction of oxidative stress in HEP G2 cells: effect on transcription factors AP-1 and NF-kappaB

Direct Effect of Ceramide on the Mitochondrial Electron Transport Chain Leads to Generation of Reactive Oxygen Species

Direct interaction of GD3 ganglioside with mitochondria generates reactive oxygen species followed by mitochondrial permeability transition, cytochrome c release, and caspase activation

Divergent role of ceramide generated by exogenous sphingomyelinases on NF-kappa B activation and apoptosis in human colon HT-29 cells.

Endoplasmic reticulum stress mediates amyloid β neurotoxicity via mitochondrial cholesterol trafficking

Evidence that the rat hepatic mitochondrial carrier is distinct from the sinusoidal and canalicular transporters for reduced glutathione. Expression studies in Xenopus laevis oocytes

Feeding S-adenosyl-L-methionine attenuates both ethanol-induced depletion of mitochondrial glutathione and mitochondrial dysfunction in periportal and perivenous rat hepatocytes

GAPDH and Autophagy Preserve Survival after Apoptotic Cytochrome c Release in the Absence of Caspase Activation

GAPDH and autophagy preserve survival after apoptotic cytochrome c release in the absence of caspase activation

GSH transport in mitochondria: defense against TNF-induced oxidative stress and alcohol-induced defect.

Ganglioside GD3 enhances apoptosis by suppressing the nuclear factor-kappa B-dependent survival pathway

Glycosphingolipids and mitochondria: role in apoptosis and disease.

Hepatocarcinogenesis and ceramide/cholesterol metabolism

How is the liver primed or sensitized for alcoholic liver disease?

Human placenta sphingomyelinase, an exogenous acidic pH-optimum sphingomyelinase, induces oxidative stress, glutathione depletion, and apoptosis in rat hepatocytes

Inhibition of rat sinusoidal GSH transporter by thioethers: specificity, sidedness, and kinetics

Mechanism of mitochondrial glutathione-dependent hepatocellular susceptibility to TNF despite NF-kappaB activation.

Metabolic therapy: lessons from liver diseases.

Mitochondria, cholesterol and amyloid beta peptide: a dangerous trio in Alzheimer disease.

Mitochondrial Glutathione: Importance and Transport

Mitochondrial Glutathione: Recent Insights and Role in Disease

Mitochondrial S-adenosyl-L-methionine transport is insensitive to alcohol-mediated changes in membrane dynamics.

Mitochondrial cholesterol accumulation in alcoholic liver disease: Role of ASMase and endoplasmic reticulum stress.

Mitochondrial cholesterol contributes to chemotherapy resistance in hepatocellular carcinoma.

Mitochondrial cholesterol in health and disease

Mitochondrial cholesterol loading exacerbates amyloid beta peptide-induced inflammation and neurotoxicity

Mitochondrial free cholesterol loading sensitizes to TNF- and Fas-mediated steatohepatitis

Mitochondrial glutathione, a key survival antioxidant

Mitochondrial glutathione: features, regulation and role in disease

Mitochondrial permeability transition induced by reactive oxygen species is independent of cholesterol-regulated membrane fluidity

Novel roles for GAPDH in cell death and carcinogenesis.

Oxidative stress and alcoholic liver disease.

Oxidative stress and altered mitochondrial function in neurodegenerative diseases: lessons from mouse models

Oxidative stress: role of mitochondria and protection by glutathione

PGE1 protection against apoptosis induced by D-galactosamine is not related to the modulation of intracellular free radical production in primary culture of rat hepatocytes

Recent Insights into the Mitochondrial Role in Autophagy and Its Regulation by Oxidative Stress

Redox control of liver function in health and disease

Role of oxidative stress generated from the mitochondrial electron transport chain and mitochondrial glutathione status in loss of mitochondrial function and activation of transcription factor nuclear factor-kappa B: studies with isolated mitochondri

S-Adenosyl-L-methionine and mitochondrial reduced glutathione depletion in alcoholic liver disease

Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor

Sensitivity of the 2-oxoglutarate carrier to alcohol intake contributes to mitochondrial glutathione depletion

Targeting glucosylceramide synthase upregulation reverts sorafenib resistance in experimental hepatocellular carcinoma

Tauroursodeoxycholic acid protects hepatocytes from ethanol-fed rats against tumor necrosis factor-induced cell death by replenishing mitochondrial glutathione.

Trafficking of ganglioside GD3 to mitochondria by tumor necrosis factor-alpha

Transcriptional regulation of the heavy subunit chain of gamma-glutamylcysteine synthetase by ionizing radiation.

Transport of reduced glutathione in hepatic mitochondria and mitoplasts from ethanol-treated rats: Effect of membrane physical properties andS-adenosyl-L-methionine

Tumor necrosis factor increases hepatocellular glutathione by transcriptional regulation of the heavy subunit chain of gamma-glutamylcysteine synthetase.