Search filters

List of works by Sejal Saglani

1α,25-dihydroxyvitamin D3 promotes CD200 expression by human peripheral and airway-resident T cells

scientific article

A video questionnaire identifies upper airway abnormalities in preschool children with reported wheeze

scientific article

Addressing unmet needs in understanding asthma mechanisms: From the European Asthma Research and Innovation Partnership (EARIP) Work Package (WP)2 collaborators

scientific article

Adolescence: the last frontier

scientific article published on 01 September 2012

Advances in the aetiology, management, and prevention of acute asthma attacks in children

scientific article published on 20 March 2019

Airway granulocytes in severe preschool wheeze: Predictive of school-age asthma attacks or disease protection

scientific article published on 01 July 2018

Airway remodeling and inflammation in symptomatic infants with reversible airflow obstruction

scientific article published on 18 January 2005

Allergy in severe asthma

scientific article

An alternative to lung transplantation

scientific article published on 01 October 2003

An approach to the management of children with problematic severe asthma

scientific article published on 07 September 2020

An infant with pneumonia, failure to thrive and persistent radiographical changes

scientific article published in July 2007

Approaches to Asthma Diagnosis in Children and Adults

Assessment of corticosteroid response in pediatric patients with severe asthma by using a multidomain approach.

scientific article

Asthma Attacks in Children: Does Blocking IgE Reduce Rhinoviral Infections?

scientific article

Asthma and allergy: the emerging epithelium

scientific article

Asthma attacks: should we nail our colours to the mast (cell)?

scientific article published in November 2016

Asthma in preschool children: the next challenge

scientific article

Asthma, atopy, and airway inflammation: what does it mean in practice?

scientific article published on 01 September 2008

Biologics for paediatric severe asthma: trick or TREAT?

scientific article published on 26 February 2019

Blood eosinophil counts rarely reflect airway eosinophilia in children with severe asthma

scientific article published on 25 January 2013

Bronchoalveolar lavage in infants with recurrent lower respiratory symptoms

scientific article published on 24 October 2014

Can HRCT be used as a marker of airway remodelling in children with difficult asthma?

scientific article

Changing prevalence of current asthma and inhaled corticosteroid treatment in the UK: population-based cohort 2006-2016

scientific article published on 04 April 2019

Childhood Asthma: Advances Using Machine Learning and Mechanistic Studies

scientific article published on 01 February 2019

Childhood severe asthma: New insights on remodelling and biomarkers

scientific article published on 12 June 2017

Comparative primary paediatric nasal epithelial cell culture differentiation and RSV-induced cytopathogenesis following culture in two commercial media

scientific article published on 26 March 2020

Corticosteroid responsiveness and clinical characteristics in childhood difficult asthma

scientific article

Cystic fibrosis and Down's syndrome: not always a poor prognosis

scientific article published on 01 April 2001

Defective IL-10 expression and in vitro steroid-induced IL-17A in paediatric severe therapy-resistant asthma.

scientific article published on 17 December 2013

Development of allergic immunity in early life.

scientific article published on July 2017

Development of the bronchial epithelial reticular basement membrane: relationship to epithelial height and age

scientific article

Developments allergy in 2019 through the eyes of Clinical and Experimental Allergy, Part II clinical allergy

scientific article published on 01 December 2020

Developments allergy in 2019 through the eyes of clinical and experimental allergy, part I mechanisms

scientific article published on 01 December 2020

Developments in the field of allergy in 2016 through the eyes of Clinical and Experimental Allergy

scientific article published on 25 October 2017

Developments in the field of allergy in 2017 through the eyes of Clinical and Experimental Allergy

scientific article published on 01 December 2018

Developments in the field of allergy mechanisms in 2015 through the eyes of Clinical & Experimental Allergy

scientific article

Developments in the field of clinical allergy in 2015 through the eyes of Clinical and Experimental Allergy

scientific article

Developments in the field of clinical allergy in 2018 through the eyes of Clinical and Experimental Allergy, Part II

scientific article published on 01 December 2019

Diagnosis and Management of Problematic Severe Asthma

scientific article published on 01 August 2020

Difficult asthma in the pre-school child

scientific article published in September 2004

Difficult-to-treat asthma in childhood

scientific article published on June 2013

Does tidal exhaled nitric oxide reflect mucosal airway inflammation in infants?

scientific article published on 29 September 2010

Dynamics of human monocytes and airway macrophages during healthy aging and after transplant

scientific article published on 01 March 2020

EAACI position statement on asthma exacerbations and severe asthma

scientific article

Early detection of airway wall remodeling and eosinophilic inflammation in preschool wheezers

scientific article published on 16 August 2007

Electronic adherence monitoring identifies severe preschool wheezers who are steroid responsive

scientific article published on 04 July 2020

Electronic monitoring of adherence to inhaled corticosteroids: an essential tool in identifying severe asthma in children

scientific article

Empyema: the use of broad range 16S rDNA PCR for pathogen detection.

scientific article

Endobronchial biopsy in childhood

scientific article published on 01 January 2008

Enhanced frequency and function of follicular T cells in the tonsils of house dust mite-sensitized children

scientific article published on 14 December 2019

Environmental factors relevant to difficult asthma

scientific article

Eosinophils in the pathogenesis of paediatric severe asthma

scientific article published on April 2014

Eosinophils in the spotlight: Finding the link between obesity and asthma.

scientific article published in August 2013

Epithelial cytokines and pulmonary allergic inflammation

scientific article

Ethnic Variation in Response to IM Triamcinolone in Children With Severe Therapy-Resistant Asthma

scientific article published on 17 September 2015

Feasibility of lung clearance index in a clinical setting in pre-school children

scientific article

Glucocorticosteroids Are Potential Confounders in Studies of Vitamin D and Asthma ⬇️

scientific article published on June 1, 2012

How to manage a child with difficult asthma?

scientific article published on 27 May 2016

IL-33 promotes airway remodeling in pediatric patients with severe steroid-resistant asthma

scientific article

Immune system dysregulation in chronic lung disease

scientific article published on 01 September 2011

Impaired innate interferon induction in severe therapy resistant atopic asthmatic children

scientific article published on 05 December 2012

Inception of early-life allergen-induced airway hyperresponsiveness is reliant on IL-13+CD4+ T cells

scientific article published on 01 September 2018

Increased airway smooth muscle in preschool wheezers who have asthma at school age.

scientific article published on 12 October 2012

Increased airway smooth muscle mass in children with asthma, cystic fibrosis, and non-cystic fibrosis bronchiectasis

scientific article published on 24 January 2008

Increased nuclear suppressor of cytokine signaling 1 in asthmatic bronchial epithelium suppresses rhinovirus induction of innate interferons

scientific article

Infection and inflammation in induced sputum from preschool children with chronic airways diseases

scientific article published on 17 December 2015

Innate helper cells: a novel cell type essential in the initiation of asthma? ⬇️

scientific article published on June 15, 2011

Innate immunity in paediatric viral wheezers is virus specific and not interferon dependent

scientific article published on 28 May 2014

Intraepithelial neutrophils in pediatric severe asthma are associated with better lung function

scientific article

Intravenous salbutamol bolus compared with an aminophylline infusion in children with severe asthma: a randomised controlled trial

scientific article published on April 2003

Investigation of young children with severe recurrent wheeze: any clinical benefit?

scientific article published on January 2006

Long-term effectiveness of a staged assessment for paediatric problematic severe asthma

scientific article

Lower airway microbiota associates with inflammatory phenotype in severe preschool wheeze

scientific article published on 21 December 2018

Lung clearance index and steroid response in pediatric severe asthma

scientific article published on 06 February 2020

Lung function in primary ciliary dyskinesia: breaking the myth that this is a mild disease

scientific article published on 23 August 2018

Lung function, airway remodeling, and inflammation in infants: outcome at 8 years

scientific article published on 25 October 2014

Lung function, airway remodelling and inflammation in symptomatic infants: outcome at 3 years.

scientific article

Lung microbiota promotes tolerance to allergens in neonates via PD-L1.

scientific article

Management of severe asthma in children

scientific article

Managing the pediatric patient with refractory asthma: a multidisciplinary approach.

scientific article

Managing wheeze in preschool children.

scientific article published on 04 February 2014

Mechanisms Mediating Pediatric Severe Asthma and Potential Novel Therapies

scientific article

Medical algorithm: Diagnosis and treatment of preschool asthma

scientific article published on 03 January 2020

Monitoring asthma in childhood: lung function, bronchial responsiveness and inflammation

scientific article published on June 2015

Monitoring asthma in children

scientific article

Multiple breath washouts in children can be shortened without compromising quality

scientific article

Novel concepts in airway inflammation and remodelling in asthma

scientific article

Onset of Structural Airway Changes in Preschool Wheezers. A Window and Target for Secondary Asthma Prevention?

scientific article published in July 2015

Opening the Window of Immune Opportunity: Treating Childhood Asthma

scientific article published on 14 August 2019

P76 Long-term effectiveness of a staged assessment for problematic severe asthma

scientific article published in December 2011

P77 Lung clearance index (LCI) in children with severe, therapy resistant asthma (STRA)

scientific article published in December 2011

P83 Is a single intramuscular dose of triamcinolone and acute bronchodilator sufficient to determine optimal lung function in children with severe therapy resistant asthma?

scientific article published in December 2011

P89 Novel mechanisms of immunomodulation by vitamin D and α-1-antitrypsin

scientific article published on 14 November 2013

Pathogenesis and prevention strategies of severe asthma exacerbations in children

scientific article

Pathophysiological features of asthma develop in parallel in house dust mite-exposed neonatal mice

scientific article

Pediatric severe asthma is characterized by eosinophilia and remodeling without T(H)2 cytokines

scientific article

Pediatric severe asthma with fungal sensitization is mediated by steroid-resistant IL-33

scientific article

Perinatal paracetamol exposure in mice does not affect the development of allergic airways disease in early life

scientific article published on 3 April 2015

Preschool wheeze: Challenges and research prospects reply to: Dr Jartti and Colleagues; in response to our manuscript entitled: Medical algorithm: Diagnosis and treatment of preschool asthma

scientific article published on 01 October 2020

Primary care of children and young people with asthma during the COVID-19 era

scientific article published on 29 October 2020

Prostacyclin as a Potential Novel Means to Manipulate Type 2 Innate Lymphoid Cell Function.

scientific article

Pulmonary epithelial barrier and immunological functions at birth and in early life - key determinants of the development of asthma? A description of the protocol for the Breathing Together study

article

Pulmonary type-2 innate lymphoid cells in paediatric severe asthma: phenotype and response to steroids

scientific article published on 29 August 2019

Quality, size, and composition of pediatric endobronchial biopsies in cystic fibrosis

scientific article published on 22 February 2007

Rebuilding a diseased lung: repair and regeneration

scientific article published in March 2013

Relationship between past airway pathology and current lung function in preschool wheezers

scientific article published on 20 July 2011

Relationship between serum vitamin D, disease severity, and airway remodeling in children with asthma

scientific article

Role of a prolonged inpatient admission when evaluating children with problematic severe asthma.

scientific article published on 31 January 2018

S33 Vitamin D and airway remodelling in paediatric severe therapy resistant asthma

scientific article published in December 2011

Safety of endobronchial biopsy in children with cystic fibrosis

scientific article published in November 2006

Safety of live attenuated influenza vaccine (LAIV) in children with moderate to severe asthma

scientific article published on 18 December 2019

Severe asthma in children

scientific article published on 25 May 2017

Severe asthma in children: therapeutic considerations

scientific article published on 01 April 2019

Severe asthma: looking beyond the amount of medication.

scientific article published on 11 October 2017

Severe therapy resistant asthma in children: translational approaches to uncover sub-phenotypes

scientific article

Should oral corticosteroids be prescribed for preschool viral wheeze?

scientific article published on 01 June 2018

Should preschool wheezers ever be treated with inhaled corticosteroids?

scientific article published on June 2007

Structurally Unsound? Why Airways Become Asthmatic

scientific article published on 01 October 2018

Symptom-pattern phenotype and pulmonary function in preschool wheezers

scientific article published on 25 June 2010

T cells in asthma: Influences of genetics, environment, and T-cell plasticity ⬇️

scientific article published on March 28, 2013

T4 Increased reticular basement membrane thickness but NOT airway smooth muscle in endobronchial biopsies of severe preschool wheezers

scientific article published on 16 November 2010

The difference between groups and individuals

scientific article

The early-life origins of asthma

scientific article published on February 2007

The need to differentiate between adults and children when treating severe asthma

scientific article published on 15 July 2015

The relationship between inflammation and remodeling in childhood asthma: A systematic review

scientific article published on 22 February 2018

The role of 1α,25-dihydroxyvitamin D3 and cytokines in the promotion of distinct Foxp3+ and IL-10+ CD4+ T cells

scientific article

The safety and quality of endobronchial biopsy in children under five years old.

scientific article published on December 2003

The utility of a multidomain assessment of steroid response for predicting clinical response to omalizumab.

scientific article published on 25 February 2016

Type 2 innate lymphoid cells in induced sputum from children with severe asthma

scientific article published on 12 August 2015

Ultrastructure of the reticular basement membrane in asthmatic adults, children and infants

scientific article published on 26 April 2006

Viral infections and the development of asthma in children

scientific article

Vitamin D and asthma in children

scientific article published on September 2011

Vitamin D binding protein and asthma severity in children

scientific article published on 28 March 2012

Vitamin D deficiency induces Th2 skewing and eosinophilia in neonatal allergic airways disease

scientific article

Vitamin D enhances production of soluble ST2, inhibiting the action of IL-33.

scientific article published on 12 November 2014

Paulina is supported by:

About Paulina

Help