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List of works by Thomas Wekerle

25 And going strong

scientific article published on 01 January 2012

A B Cell Epitope Peptide Derived from the Major Grass Pollen Allergen Phl p 1 Boosts Allergen-Specific Secondary Antibody Responses without Allergen-Specific T Cell Help

scientific article published on 16 January 2017

Adoptive Cell Therapy in Mice Sensitized to a Grass Pollen Allergen

scientific article published in 2024

Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment

scientific article published on 01 April 2000

Anti-CD154 mAb and rapamycin induce T regulatory cell mediated tolerance in rat-to-mouse islet transplantation

scientific article (publication date: 26 April 2010)

Anti-CD154 mAb treatment but not recipient CD154 deficiency leads to long-term survival of xenogeneic islet grafts

scientific article published on 01 May 2005

Anti-LFA-1 or rapamycin overcome costimulation blockade-resistant rejection in sensitized bone marrow recipients.

scientific article published on 13 December 2012

Bcl-2 inhibition to overcome memory cell barriers in transplantation.

scientific article published in February 2014

Belatacept and Tregs: friends or foes?

scientific article published on 01 April 2012

Belatacept treatment for two yr after liver transplantation is not associated with operational tolerance

scientific article published on 10 December 2014

Belatacept-based immunosuppression in de novo liver transplant recipients: 1-year experience from a phase II randomized study

scientific article

Belatacept: from rational design to clinical application

scientific article published on 07 December 2011

CTLA4-Ig immunosuppressive activity at the level of dendritic cell/T cell crosstalk

scientific article published on 20 February 2013

CTLA4-Ig preserves thymus-derived T regulatory cells

article

CTLA4Ig Improves Murine iTreg Induction via TGFβ and Suppressor Function In Vitro

scientific article published on 02 July 2018

CTLA4Ig promotes the induction of hematopoietic chimerism and tolerance independently of Indoleamine-2,3-dioxygenase

scientific article

Cell-based therapy in allergy

scientific article published on January 2011

Combination of extended donor criteria and changes in the Model for End-Stage Liver Disease score predict patient survival and primary dysfunction in liver transplantation: a retrospective analysis.

scientific article published on March 2007

Comparison between C0 and C2 monitoring in de novo renal transplant recipients: retrospective analysis of a single-center experience

scientific article published in December 2004

Costimulation blockade with belatacept in renal transplantation

scientific article published in August 2005

Costimulatory pathways in transplantation

scientific article

Coupling of a Major Allergen to the Surface of Immune Cells for Use in Prophylactic Cell Therapy for the Prevention of IgE-Mediated Allergy

scientific article published in 2024

Deletional and regulatory mechanisms coalesce to drive transplantation tolerance through mixed chimerism

scientific article

Dipeptidyl peptidase IV (DPPIV/CD26) inhibition does not improve engraftment of unfractionated syngeneic or allogeneic bone marrow after nonmyeloablative conditioning

scientific article published on 13 November 2011

Distinct roles for major and minor antigen barriers in chimerism-based tolerance under irradiation-free conditions

scientific article published on 06 July 2020

Donor CD4 T Cells Trigger Costimulation Blockade-Resistant Donor Bone Marrow Rejection Through Bystander Activation Requiring IL-6

scientific article published on 06 August 2014

Downsizing of the donor lung: peripheral segmental resections and lobar transplantation

scientific article published on 01 November 1997

Earlier low-dose TBI or DST overcomes CD8+ T-cell-mediated alloresistance to allogeneic marrow in recipients of anti-CD40L

scientific article published on 01 January 2004

Early regulation of CD8 T cell alloreactivity by CD4+CD25- T cells in recipients of anti-CD154 antibody and allogeneic BMT is followed by rapid peripheral deletion of donor-reactive CD8+ T cells, precluding a role for sustained regulation

scientific article published on 01 September 2005

Effect of intraportal infusion of tacrolimus on ischaemic reperfusion injury in orthotopic liver transplantation: a randomized controlled trial

scientific article

Engraftment of retrovirally transduced Bet v 1-GFP expressing bone marrow cells leads to allergen-specific tolerance.

scientific article

Expression of a Major Plant Allergen as Membrane-Anchored and Secreted Protein in Human Cells with Preserved T Cell and B Cell Epitopes

article

Extrathymic T cell deletion and allogeneic stem cell engraftment induced with costimulatory blockade is followed by central T cell tolerance

scientific article

Hematopoietic chimerism and tolerance of T cells, B cells, and NK cells

scientific article published on 01 December 1998

Hybrid Resistance to Parental Bone Marrow Grafts in Non-Lethally Irradiated Mice

article

IDO and regulatory T cell support are critical for cytotoxic T lymphocyte-associated Ag-4 Ig-mediated long-term solid organ allograft survival.

scientific article published on 30 November 2011

Immune tolerance in transplantation

scientific article published in August 2017

Immunosenescence does not abrogate engraftment of murine allogeneic bone marrow

scientific article published in June 2013

Incidence and outcome of major non-pulmonary surgical procedures in lung transplant recipients.

scientific article published on November 1997

Induction of mixed chimerism through transplantation of CD45-congenic mobilized peripheral blood stem cells after nonmyeloablative irradiation.

scientific article

Induction of tolerance

scientific article published on April 2004

Intrahepatic splenic tissue in a patient with recurrent idiopathic thrombocytopenic purpura ⬇️

scientific article published on May 1, 1998

Long-term outcome of belatacept therapy in de novo kidney transplant recipients - a case-match analysis

article

Lung transplantation for primary pulmonary hypertension and giant pulmonary artery aneurysm

scientific article published on 01 March 1998

Macrophage depletion prolongs discordant but not concordant islet xenograft survival

scientific article published on 01 March 2005

Management of severe bronchial ischemia after bilateral sequential lung transplantation

scientific article published on 01 December 1992

Mechanisms involved in the establishment of tolerance through costimulatory blockade and BMT: lack of requirement for CD40L-mediated signaling for tolerance or deletion of donor-reactive CD4+ cells

scientific article published on 01 November 2001

Mechanistic and therapeutic role of regulatory T cells in tolerance through mixed chimerism

scientific article published on December 2010

Minimal conditioning required in a murine model of T cell depletion, thymic irradiation and high-dose bone marrow transplantation for the induction of mixed chimerism and tolerance

scientific article

Minor Antigen Disparities Impede Induction of Long Lasting Chimerism and Tolerance through Bone Marrow Transplantation with Costimulation Blockade

scientific article

Mixed chimerism for the induction of tolerance: potential applicability in clinical composite tissue grafting

scientific article published on 01 September 1998

Mixed chimerism through donor bone marrow transplantation: a tolerogenic cell therapy for application in organ transplantation

scientific article published on February 2012

Modulating T-cell costimulation as new immunosuppressive concept in organ transplantation

scientific article published on August 2012

Molecular signature of mice T lymphocytes following tolerance induction by allogeneic BMT and CD40-CD40L costimulation blockade.

scientific article published on February 2006

Murine mobilized peripheral blood stem cells have a lower capacity than bone marrow to induce mixed chimerism and tolerance.

scientific article

Murine models of transplantation tolerance through mixed chimerism: advances and roadblocks

scientific article published on 10 April 2017

NO AUGMENTATION OF INDOLEAMINE 2,3-DIOXYGENASE (IDO) ACTIVITY THROUGH BELATACEPT TREATMENT IN LIVER TRANSPLANT RECIPIENTS.

scientific article published on 22 December 2017

No evidence for recipient-derived hepatocytes in serial biopsies of sex-mismatched liver transplants.

scientific article published in November 2012

Persistent molecular microchimerism induces long-term tolerance towards a clinically relevant respiratory allergen

scientific article published on August 2012

Phylogenetic disparity influences the predominance of direct over indirect pathway of antigen presentation in islet xenotransplantation

scientific article published on 01 January 2005

Polyclonal Recipient nTregs Are Superior to Donor or Third-Party Tregs in the Induction of Transplantation Tolerance

scientific article

Prophylactic Bisphosphonate Treatment Prevents Bone Fractures After Liver Transplantation

scientific article published on 19 May 2007

Rapamycin and CTLA4Ig synergize to induce stable mixed chimerism without the need for CD40 blockade.

scientific article

Recent progress in tolerance induction through mixed chimerism.

scientific article published on 27 June 2007

Regulatory T Cells Promote Natural Killer Cell Education in Mixed Chimeras.

scientific article

Resistance to ABT-737 in activated T lymphocytes: molecular mechanisms and reversibility by inhibition of the calcineurin-NFAT pathway

scientific article

Role of CD40-CD154 pathway in the rejection of concordant and discordant xenogeneic islets

scientific article published on 01 January 2005

Role of peripheral clonal deletion in tolerance induction with bone marrow transplantation and costimulatory blockade

scientific article published on 01 February 1999

Short-term effects of high-dose zoledronic acid treatment on bone mineralization density distribution after orthotopic liver transplantation

scientific article published on 19 August 2008

Short-term immunosuppression facilitates induction of mixed chimerism and tolerance after bone marrow transplantation without cytoreductive conditioning

scientific article published in July 2005

Stable prodrugs of n-butyric acid: suppression of T cell alloresponses in vitro and prolongation of heart allograft survival in a fully allogeneic rat strain combination

scientific article published on 01 December 1999

Strategies to overcome the ABO barrier in kidney transplantation

scientific article published on September 2015

T-regulatory cell treatment prevents chronic rejection of heart allografts in a murine mixed chimerism model

scientific article

T-regulatory cells-what relationship with immunosuppressive agents?

scientific article published on December 2008

Taming the ABO barrier in transplantation

scientific article published in October 2013

The advantage of allocating kidneys from old cadaveric donors to old recipients: a single-center experience

scientific article published in July 2006

The critical role of mouse CD4+ cells in the rejection of highly disparate xenogeneic pig thymus grafts

scientific article published on 01 May 2000

The influence of immunosuppressive drugs on tolerance induction through bone marrow transplantation with costimulation blockade

scientific article published on 14 November 2002

The role of natural killer T cells in costimulation blockade-based mixed chimerism

scientific article

The role of non-deletional tolerance mechanisms in a murine model of mixed chimerism with costimulation blockade

scientific article published on 01 June 2005

The site of allergen expression in hematopoietic cells determines the degree and quality of tolerance induced through molecular chimerism

scientific article published on 15 July 2013

Therapeutic efficacy of polyclonal tregs does not require rapamycin in a low-dose irradiation bone marrow transplantation model

scientific article published in August 2011

Tolerance in mixed chimerism - a role for regulatory cells?

scientific article published in October 2004

Tolerance through bone marrow transplantation with costimulation blockade

scientific article

Toward MSC in Solid Organ Transplantation: 2008 Position Paper of the MISOT Study Group

article

Transplantation of discordant xenogeneic islets using repeated therapy with anti-CD154.

scientific article published in June 2005

Transplantation tolerance through mixed chimerism ⬇️

scientific article published on August 31, 2010

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