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List of works by Shuji Kaneko

'Cut-open' method: a new method for Xenopus oocytes that enables intracellular perfusion and stable current recording ⬇️

scientific article published on 01 March 1998

A critical role of TRPM2 in neuronal cell death by hydrogen peroxide

scientific journal article

A facilitatory role of endogenous somatostatin in long-term potentiation of the mossy fiber-CA3 system in guinea-pig hippocampus

scientific article published in August 1991

A long-lasting potentiation of calmodulin-mediated chloride channel activity without a mediation of protein kinase C in Xenopus oocytes injected with rat brain mRNA.

scientific article published in April 1990

A new designer drug 5F-ADB activates midbrain dopaminergic neurons but not serotonergic neurons

scientific article published in January 2016

A pathophysiological role of TRPV1 in ischemic injury after transient focal cerebral ischemia in mice

scientific article published on 8 October 2015

A rat long-lasting cystitis model induced by intravesical injection of hydrogen peroxide

scientific article published on 27 February 2017

Acceleration of serotonin transporter transport-associated current by 3,4-methylenedioxymethamphetamine (MDMA) under acidic conditions

scientific article published on 26 September 2007

Activation of GABAergic Neurons in the Nucleus Accumbens Mediates the Expression of Cocaine-Associated Memory

scientific article published on 01 January 2018

Activation of mitochondrial transient receptor potential vanilloid 1 channel contributes to microglial migration

scientific article

Activation of the beta-adrenoceptor-protein kinase A signaling pathway within the ventral bed nucleus of the stria terminalis mediates the negative affective component of pain in rats.

scientific article published in July 2008

Acute cold hypersensitivity characteristically induced by oxaliplatin is caused by the enhanced responsiveness of TRPA1 in mice.

scientific article published on 28 July 2012

Adenosine 5'-triphosphate inhibits slow depolarization induced by repetitive dorsal root stimulation via P2Y purinoceptors in substantia gelatinosa neurons of the adult rat spinal cord slices with the dorsal root attached

scientific article published in March 2002

Alpha-tocotrienol provides the most potent neuroprotection among vitamin E analogs on cultured striatal neurons

scientific article published in November 2004

Alternative splicing of Cav2 genes and their functional significance.

scientific article

Aminoglutethimide prevents excitotoxic and ischemic injuries in cortical neurons

scientific article published on April 2006

An Adenosine A Receptor Antagonist Improves Multiple Symptoms of Repeated Quinpirole-Induced Psychosis

scientific article published on 01 January 2019

Antagonism of NMDA receptors by sigma receptor ligands attenuates chemical ischemia-induced neuronal death in vitro

scientific article (publication date: 29 November 2002)

Apoptotic DNA fragmentation and upregulation of Bax induced by transient ischemia of the rat retina

scientific article published in January 1999

Attenuated lipopolysaccharide-induced inflammatory bladder hypersensitivity in mice deficient of transient receptor potential ankilin1

scientific article published in Scientific Reports

Augmentation of serotonin release by sustained exposure to MDMA and methamphetamine in rat organotypic mesencephalic slice cultures containing raphe serotonergic neurons.

scientific article published on 24 July 2008

Automated electrophysiological system for the measurement of transporter/channel activities ⬇️

scientific article published on 01 December 2011

Bidirectional modulation of long-term potentiation by carbachol via M1 and M2 muscarinic receptors in guinea pig hippocampal mossy fiber-CA3 synapses

scientific article

Binding of G alpha(o) N terminus is responsible for the voltage-resistant inhibition of alpha(1A) (P/Q-type, Ca(v)2.1) Ca(2+) channels

scientific article (publication date: 3 August 2001)

Biochemical changes related to aging in the senescence-accelerated mouse

scientific article published on 01 January 1989

Ca2+ mobilization mediated by transient receptor potential canonical 3 is associated with thrombin-induced morphological changes in 1321N1 human astrocytoma cells.

scientific article published in September 2008

Calumin, a Ca²⁺-binding protein on the endoplasmic reticulum, alters the ion permeability of Ca²⁺ release-activated Ca²⁺ (CRAC) channels

scientific article published on 16 December 2011

Characterization of the tritium-labeled analog of L-threo-beta-benzyloxyaspartate binding to glutamate transporters

scientific article published on 17 October 2006

Chronic antidepressant potentiates spontaneous activity of dorsal raphe serotonergic neurons by decreasing GABAB receptor-mediated inhibition of L-type calcium channels

scientific article published on 19 October 2017

Chronic effects of antidepressants on serotonin release in rat raphe slice cultures: high potency of milnacipran in the augmentation of serotonin release.

scientific article

Cold sensitivity of TRPA1 is unveiled by the prolyl hydroxylation blockade-induced sensitization to ROS

scientific article

Competent Route to Unsymmetric Dimer Architectures: Total Syntheses of (-)-Lycodine and (-)-Complanadines A and B, and Evaluation of Their Neurite Outgrowth Activities.

scientific article

Control of intermale aggression by medial prefrontal cortex activation in the mouse

scientific article

Cut-open recording techniques

scientific article published in January 1998

Cyclic AMP facilitates slow-inactivating Ca2+ channel currents expressed by Xenopus oocyte after injection of rat brain mRNA.

scientific article published in December 1987

Depletion of intracellular glutathione increases susceptibility to nitric oxide in mesencephalic dopaminergic neurons

scientific article

Dibutyryl cyclic AMP induces differentiation of human neuroblastoma SH-SY5Y cells into a noradrenergic phenotype

scientific article

Different drug-susceptibilities of long-term potentiation in three input systems to the CA3 region of the guinea pig hippocampus in vitro

scientific article

Differential contribution of spinal mitogen-activated protein kinases to the phase of long-lasting allodynia evoked by intrathecal administration of ATP in rats.

scientific article published in June 2008

Differential regulation of N- and Q-type Ca2+ channels by cyclic nucleotides and G-proteins

scientific article published in January 1998

Direct evidence for increase in excitatory amino acids release during mossy fiber LTP in rat hippocampal slices as revealed by the patch sensor methods

scientific article

Distinct Mechanism of Cysteine Oxidation-Dependent Activation and Cold Sensitization of Human Transient Receptor Potential Ankyrin 1 Channel by High and Low Oxaliplatin.

scientific article

Distinct action of the α-glucosidase inhibitor miglitol on SGLT3, enteroendocrine cells, and GLP1 secretion

scientific article published on 8 December 2014

Effects of B vitamins on glutamate-induced neurotoxicity in retinal cultures

article

Effects of repeated administration of deer antler extract on biochemical changes related to aging in senescence-accelerated mice

scientific article published on 01 July 1988

Facilitative effect of a glutamate transporter inhibitor (2S,3S)-3-{3-[4-(trifluoromethyl)benzoylamino]benzyloxy}aspartate on the expression of methamphetamine-induced behavioral sensitization in rats

scientific article published on 3 December 2005

Functional expression of Ca(2+)-mobilizing opioid receptors in Xenopus oocytes injected with rat brain mRNA.

scientific article

Galanin inhibits long-term potentiation at Schaffer collateral-CA1 synapses in guinea-pig hippocampal slices

scientific article published in July 1996

Gene transfer of GLT-1, a glutamate transporter, into the nucleus accumbens shell attenuates methamphetamine- and morphine-induced conditioned place preference in rats

scientific article published in December 2005

Habenular lesion attenuates methamphetamine-induced inhibition of dopamine neuronal activity in the substantia nigra pars compacta of rats

scientific article

Heterologous expression of a mammalian ABC transporter in plant and its application to phytoremediation.

scientific article published in June 2006

Human sodium phosphate transporter 4 (hNPT4/SLC17A3) as a common renal secretory pathway for drugs and urate

scientific article

Hypoxia-induced sensitisation of TRPA1 in painful dysesthesia evoked by transient hindlimb ischemia/reperfusion in mice

scientific article

Identification of a novel planarian G-protein-coupled receptor that responds to serotonin in Xenopus laevis oocytes

scientific article published in October 2009

Increased Ca2+ channel currents in cerebellar Purkinje cells of the ataxic groggy rat

scientific article published on 25 August 2007

Inhalation administration of valerena-4,7(11)-diene from Nardostachys chinensis roots ameliorates restraint stress-induced changes in murine behavior and stress-related factors.

scientific article

Inhibition by [Arg8]-vasopressin of long term potentiation in guinea pig hippocampal slice

scientific article published in May 1998

Inhibition of TRPC5 channels by Ca2+-binding protein 1 in Xenopus oocytes.

scientific article published on 14 May 2005

Inhibition of glutamatergic transmission by morphine in the basolateral amygdaloid nucleus reduces pain-induced aversion

scientific article published in July 2007

Inhibition of histone deacetylases enhances the function of serotoninergic neurons in organotypic raphe slice cultures.

scientific article published on 18 March 2015

Inhibitory effects of bifemelane on brain Ca2+ channel subtypes expressed in Xenopus oocytes

scientific article published in September 1998

Inhibitory influence via 5-HT3 receptors on the induction of LTP in mossy fiber-CA3 system of guinea-pig hippocampal slices

scientific article published in January 1994

Inhibitory role of supraspinal P2X3/P2X2/3 subtypes on nociception in rats.

scientific article published on 5 June 2006

Interspecies differences in the population of multiple glutamate receptors expressed in Xenopus oocytes after injection of guinea pig, mouse and rat forebrain mRNAs

scientific article published in September 1990

Intracellular Ca2+ store-operated influx of Ca2+ through TRP-R, a rat homolog of TRP, expressed in Xenopus oocytes

scientific article published in June 1998

Intracerebroventricular administration of angiotensin II attenuates morphine-induced analgesia in mice

scientific article published in November 1985

Intrathecal administration of ATP produces long-lasting allodynia in rats: Differential mechanisms in the phase of the induction and maintenance

scientific article published on 01 June 2007

Involvement of M2 receptor in an enhancement of long-term potentiation by carbachol in Schaffer collateral-CA1 synapses of hippocampal slices

scientific article published in February 1997

Involvement of NOX1/NADPH oxidase in morphine-induced analgesia and tolerance

scientific article published on 01 December 2011

Involvement of TRPM2 in a wide range of inflammatory and neuropathic pain mouse models.

scientific article published on 18 February 2015

Involvement of TRPM2 in peripheral nerve injury-induced infiltration of peripheral immune cells into the spinal cord in mouse neuropathic pain model.

scientific article

Involvement of direct inhibition of NMDA receptors in the effects of sigma-receptor ligands on glutamate neurotoxicity in vitro

scientific article published in September 2000

Involvement of postsynaptic G proteins in hippocampal long-term potentiation

scientific article published in May 1992

Involvement of spinally-infiltrated immune cells in peripheral nerve injury-induced neuropathic pain: roles of TRPM2

scientific article published in November 2013

Involvement of the bed nucleus of the stria terminalis activated by the central nucleus of the amygdala in the negative affective component of morphine withdrawal in rats

scientific article published in January 2005

Involvement of the bed nucleus of the stria terminalis in the negative affective component of visceral and somatic pain in rats

scientific article published on 13 November 2006

Kcna1-mutant rats dominantly display myokymia, neuromyotonia and spontaneous epileptic seizures

scientific journal article

Ketamine-induced prefrontal serotonin release is mediated by cholinergic neurons in the pedunculopontine tegmental nucleus

scientific article published on 23 January 2018

Long-lasting pain-related behaviors in mouse chronic cystitis model induced by a single intravesical injection of hydrogen peroxide.

scientific article published on 19 November 2015

Manipulation of dorsal raphe serotonergic neurons modulates active coping to inescapable stress and anxiety-related behaviors in mice and rats

scientific article published on 30 October 2018

Mechanisms of oxygen glucose deprivation-induced glutamate release from cerebrocortical slice cultures

scientific article published in October 2004

Mechanisms of substrate transport-induced clustering of a glial glutamate transporter GLT-1 in astroglial-neuronal cultures.

scientific article published in November 2008

Metabotropic responses to acetylcholine and serotonin of Xenopus oocytes injected with rat brain mRNA are transduced by different G-protein subtypes

scientific article

Mobilization of intracellular Ca2+ and stimulation of cyclic AMP production by kappa opioid receptors expressed in Xenopus oocytes

scientific article

Modulation of Ca2+ channel currents by a novel antidementia drug N-(4-Acetyl-1-piperazinyl)-p-fluorobenzamide monohydrate (FK960) in rat hippocampal neurons

scientific article published on 20 October 2003

Motor vehicle collisions caused by the 'super-strength' synthetic cannabinoids, MAM-2201, 5F-PB-22, 5F-AB-PINACA, 5F-AMB and 5F-ADB in Japan experienced from 2012 to 2014.

scientific article

N-Methyl-D-aspartate receptors contribute to the maintenance of dopaminergic neurons in rat midbrain slice cultures

scientific article published in May 2003

Neuroprotective effects of alpha-tocopherol on oxidative stress in rat striatal cultures

scientific article published in March 2003

Neuropsychotoxicity of abused drugs: molecular and neural mechanisms of neuropsychotoxicity induced by methamphetamine, 3,4-methylenedioxymethamphetamine (ecstasy), and 5-methoxy-N,N-diisopropyltryptamine (foxy).

scientific article published on 16 January 2008

Neurotropin inhibits neuronal activity through potentiation of sustained Kv currents in primary cultured DRG neurons

scientific article published on 31 May 2018

Nicotinic acetylcholine receptor-mediated neuroprotection by donepezil against glutamate neurotoxicity in rat cortical neurons

scientific article published on 6 May 2003

Nicotinic alpha 7 receptors protect against glutamate neurotoxicity and neuronal ischemic damage.

scientific article

Noradrenergic inhibition of the release of substance P from the primary afferents in the rabbit spinal dorsal horn

scientific article published in December 1985

Novel mouse model of chronic inflammatory and overactive bladder by a single intravesical injection of hydrogen peroxide.

scientific article published on 30 March 2013

Olanzapine augments the effect of selective serotonin reuptake inhibitors by suppressing GABAergic inhibition via antagonism of 5-HT₆ receptors in the dorsal raphe nucleus.

scientific article published on 8 April 2015

Opioid activity of enkephalin analogues containing the kyotorphin-related structure in the N-terminus

scientific article published in April 1984

Patch sensor detection of glutamate release evoked by a single electrical shock

scientific article published on 01 August 1995

Pathophysiological Role of Transient Receptor Potential Ankyrin 1 in a Mouse Long-Lasting Cystitis Model Induced by an Intravesical Injection of Hydrogen Peroxide.

scientific article published on 7 November 2017

Pharmacological approach for elucidating the role of dorsal raphe serotonin neurons in mood/emotion regulation

scientific article published on 01 January 2017

Pharmacological characterization of standard analgesics on oxaliplatin-induced acute cold hypersensitivity in mice

scientific article published on 27 March 2014

Physiological and Pathophysiological Roles of Transient Receptor Potential Channels in Microglia-Related CNS Inflammatory Diseases

scientific article published on 01 January 2018

Positive regulation of capacitative Ca2+ entry by intracellular Ca2+ in Xenopus oocytes expressing rat TRP4.

scientific article published in September 2000

Possible coupling of prostaglandin E receptor EP(1) to TRP5 expressed in Xenopus laevis oocytes

scientific article

Potentiation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA)-selective glutamate receptor function by a nootropic drug, idebenone.

scientific article published in January 1994

Pregnenolone sulphate attenuates AMPA cytotoxicity on rat cortical neurons

scientific article published in May 2005

Prevention of antipsychotic-induced hyperglycaemia by vitamin D: a data mining prediction followed by experimental exploration of the molecular mechanism

scientific article

Preventive and alleviative effect of tramadol on neuropathic pain in rats: roles of α₂-adrenoceptors and spinal astrocytes

scientific article published on 04 February 2014

Prostaglandin E2 protects cultured cortical neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity

scientific article published on 01 November 1994

Protective effects of 1 alpha,25-(OH)(2)D(3) against the neurotoxicity of glutamate and reactive oxygen species in mesencephalic culture

scientific article published in May 2001

Purification and identification of endogenous anti-opioid substances from bovine brain

scientific article

Raphe AMPA receptors and nicotinic acetylcholine receptors mediate ketamine-induced serotonin release in the rat prefrontal cortex.

scientific article published on 23 May 2014

Reactive oxygen species derived from NOX1/NADPH oxidase enhance inflammatory pain.

scientific article

Reactive oxygen species signaling in the regulation of microglial functions - TRP channel-mediated novel mechanisms of microglial activation

scientific article published on 01 January 2016

Reciprocal regulation of ATPgammaS-induced monocyte chemoattractant protein-1 production by ERK and p38 MAP kinases in rat corticostriatal slice cultures

scientific journal article

Regulation of N-methyl-D-aspartate cytotoxicity by neuroactive steroids in rat cortical neurons.

scientific article

Repeated exposure to methamphetamine, cocaine or morphine induces augmentation of dopamine release in rat mesocorticolimbic slice co-cultures

scientific article

Role of enhanced noradrenergic transmission within the ventral bed nucleus of the stria terminalis in visceral pain-induced aversion in rats

scientific article

Role of the 5-HT4 receptor in chronic fluoxetine treatment-induced neurogenic activity and granule cell dematuration in the dentate gyrus

scientific article published on 15 May 2015

Roles of Transient Receptor Potential Ankyrin 1 in Oxaliplatin-Induced Peripheral Neuropathy

scientific article published on January 2017

Roles of endogenous cholinergic neurons in the induction of long-term potentiation at hippocampal mossy fiber synapses

scientific article published in July 1994

Roles of transient receptor potential melastatin 2 expressed on immune cells in neuropathic pain

scientific article

SLC1 glutamate transporters and diseases: psychiatric diseases and pathological pain

scientific article published on July 2013

Scallop DMT functions as a Ca2+ transporter

scientific article published on 9 April 2005

Sedative effects of inhaled essential oil components of traditional fragrance Pogostemon cablin leaves and their structure-activity relationships

scientific article

Separate mechanisms of long-term potentiation in two input systems to CA3 pyramidal neurons of rat hippocampal slices as revealed by the whole-cell patch-clamp technique

scientific article published in November 1991

Sequential PET estimation of cerebral oxygen metabolism with spontaneous respiration of 15O-gas in mice with bilateral common carotid artery stenosis

scientific article published in January 2017

Serofendic acid prevents acute glutamate neurotoxicity in cultured cortical neurons

scientific article published in September 2003

Serofendic acid, a neuroprotective substance derived from fetal calf serum, inhibits mitochondrial membrane depolarization and caspase-3 activation

scientific article published on 3 May 2006

Some physiological and pharmacological properties of slow depolarization of substantia gelatinosa neurons by repetitive stimulation of C-fibers of dorsal root in adult rat spinal cord slices with dorsal root attached

scientific article published in October 1999

Sphingosine-1-phosphate induces Ca2+ signaling and CXCL1 release via TRPC6 channel in astrocytes

scientific article

Spinal astrocytes as therapeutic targets for pathological pain

scientific article

Stimulating effect of deer antler extract on protein synthesis in senescence-accelerated mice in vivo

scientific article published on 01 July 1988

Stimulation of transient receptor potential vanilloid 4 channel suppresses abnormal activation of microglia induced by lipopolysaccharide

scientific article published on 13 February 2012

Superoxide dismutase activity in organotypic midbrain-striatum co-cultures is associated with resistance of dopaminergic neurons to excitotoxicity.

scientific article

Sustained exposure to 3,4-methylenedioxymethamphetamine induces the augmentation of exocytotic serotonin release in rat organotypic raphe slice cultures.

scientific article published on 19 May 2010

TRPM2 Channel Aggravates CNS Inflammation and Cognitive Impairment via Activation of Microglia in Chronic Cerebral Hypoperfusion.

scientific article published on 5 March 2018

TRPM2 Exacerbates Central Nervous System Inflammation in Experimental Autoimmune Encephalomyelitis by Increasing Production of CXCL2 Chemokines.

scientific article published on 10 September 2018

TRPM2 confers susceptibility to social stress but is essential for behavioral flexibility

scientific article published on 28 September 2018

TRPM2 contributes to LPS/IFNγ-induced production of nitric oxide via the p38/JNK pathway in microglia.

scientific article

TRPM2 contributes to inflammatory and neuropathic pain through the aggravation of pronociceptive inflammatory responses in mice.

scientific article

TRPV1 stimulation triggers apoptotic cell death of rat cortical neurons

scientific journal article

TRPV4 is functionally expressed in oligodendrocyte precursor cells and increases their proliferation.

scientific article

Taxanes and platinum derivatives impair Schwann cells via distinct mechanisms

scientific article

The Crotalaria juncea metal transporter CjNRAMP1 has a high Fe uptake activity, even in an environment with high Cd contamination

scientific article published on 01 January 2018

The ataxic groggy rat has a missense mutation in the P/Q-type voltage-gated Ca2+ channel alpha1A subunit gene and exhibits absence seizures

scientific article

The impact of mouse strain-specific spatial and temporal immune responses on the progression of neuropathic pain

scientific article published on 29 August 2018

The involvement of aldose reductase in alterations to neurotrophin receptors and neuronal cytoskeletal protein mRNA levels in the dorsal root ganglion of streptozotocin-induced diabetic rats

scientific article published in January 2010

The synthetic cannabinoid 5F-AMB changes the balance between excitation and inhibition of layer V pyramidal neurons in the mouse medial prefrontal cortex

scientific article published on 02 June 2018

The use of Xenopus oocytes to evaluate drugs affecting brain Ca2+ channels: effects of bifemelane and several nootropic agents

scientific article published in July 1990

Thermosensitive Ion Channel Activation in Single Neuronal Cells by Using Surface-Engineered Plasmonic Nanoparticles

scientific article published on 6 August 2015

Transient receptor potential canonical 3 (TRPC3) mediates thrombin-induced astrocyte activation and upregulates its own expression in cortical astrocytes.

scientific article published on September 2010

Transient receptor potential canonical 3 inhibitor Pyr3 improves outcomes and attenuates astrogliosis after intracerebral hemorrhage in mice

scientific article

Tremor dominant Kyoto (Trdk) rats carry a missense mutation in the gene encoding the SK2 subunit of small-conductance Ca2+-activated K+ channel.

scientific article

Utility of organotypic raphe slice cultures to investigate the effects of sustained exposure to selective 5-HT reuptake inhibitors on 5-HT release

scientific article

Yokukansan inhibits morphine tolerance and physical dependence in mice: the role of α₂A-adrenoceptor

scientific article published on 13 October 2012

[EXPRESS] Colchicine alleviates acute postoperative pain but delays wound repair in mice: roles of neutrophils and macrophages

scientific article

[Introduction: current status, characteristics, and problems of ion channel drug discovery]

scientific article published on 01 November 2005

[Pathophysiological roles of transient receptor potential channels in glial cells]

scientific article published on 01 March 2010

[Pathophysiology of immune cells during the progression of cerebral ischemic injury - involvement of TRPM2-mediated induction of iNOS in microglia/macrophage]

scientific article published on 01 September 2014

[Roles of TRPA1 in acute peripheral neuropathy characteristically induced by oxaliplatin]

scientific article published on 01 February 2013

p75-mediated neuroprotection by NGF against glutamate cytotoxicity in cortical cultures

article

sigma receptor ligands attenuate N-methyl-D-aspartate cytotoxicity in dopaminergic neurons of mesencephalic slice cultures

scientific article

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