List of works - Wen-jun Shen

A Novel Role of Salt-Inducible Kinase 1 (SIK1) in the Post-Translational Regulation of Scavenger Receptor Class B Type 1 Activity.

scientific article published on 16 November 2015

ACTH Regulation of Adrenal SR-B1

scientific article

Ablation of vimentin results in defective steroidogenesis

scientific article

Adipocytes decrease Runx2 expression in osteoblastic cells: roles of PPARγ and adiponectin

scientific article published on November 2010

Adipose Triglyceride Lipase, Not Hormone-Sensitive Lipase, Is the Primary Lipolytic Enzyme in Fasting Elephant Seals (Mirounga angustirostris).

scientific article

Adrenal neutral cholesteryl ester hydrolase: identification, subcellular distribution, and sex differences

scientific article published in March 2002

Age-related modulation of the effects of obesity on gene expression profiles of mouse bone marrow and epididymal adipocytes

scientific article

Anti-Hyperlipidemic Effects of Synthetic Analogs of Nordihydroguaiaretic acid (NDGA) in Dyslipidemic Rats

scientific article published on 10 December 2018

Cardiac overexpression of hormone-sensitive lipase inhibits myocardial steatosis and fibrosis in streptozotocin diabetic mice

scientific article published on 15 April 2008

Cholesterol ester droplets and steroidogenesis

scientific article

Creosote bush-derived NDGA attenuates molecular and pathological changes in a novel mouse model of non-alcoholic steatohepatitis (NASH)

scientific article published on 12 August 2019

Differential roles of cysteine residues in the cellular trafficking, dimerization, and function of the high-density lipoprotein receptor, SR-BI.

scientific article published on 29 November 2011

Effect of Creosote Bush-Derived NDGA on Expression of Genes Involved in Lipid Metabolism in Liver of High-Fructose Fed Rats: Relevance to NDGA Amelioration of Hypertriglyceridemia and Hepatic Steatosis

scientific article published on 22 September 2015

Effects of rosiglitazone and high fat diet on lipase/esterase expression in adipose tissue

scientific article published on 6 December 2006

Evidence for protein‐mediated fatty acid efflux by adipocytes ⬇️

scientific article published on October 25, 2011

Fat-specific protein 27 modulates nuclear factor of activated T cells 5 and the cellular response to stress

scientific article published on 11 December 2012

Fatty acid-binding protein-hormone-sensitive lipase interaction. Fatty acid dependence on binding.

scientific article published on 16 September 2003

Feedback inhibition of CREB signaling by p38 MAPK contributes to the negative regulation of steroidogenesis

scientific article published on 16 March 2017

Function of hormone-sensitive lipase in diacylglycerol-protein kinase C pathway

scientific article

Functional analysis of the promoter region of a nodule-enhanced glutamine synthetase gene from Phaseolus vulgaris L

article

Functional interaction of hormone-sensitive lipase and perilipin in lipolysis

scientific article published on 10 June 2009

Gene expression profile of human skeletal muscle and adipose tissue of Chinese Han patients with type 2 diabetes mellitus

scientific article published in October 2009

Generation of novel adipocyte monolayer cultures from embryonic stem cells

scientific article published on 01 June 2007

Hormonal regulation of microRNA expression in steroid producing cells of the ovary, testis and adrenal gland

scientific article

Hormone-sensitive lipase functions as an oligomer

scientific article (publication date: 7 March 2000)

Hormone-sensitive lipase is required for high-density lipoprotein cholesteryl ester-supported adrenal steroidogenesis

scientific journal article

Hormone-sensitive lipase knockouts

scientific article

Hormone-sensitive lipase modulates adipose metabolism through PPARγ.

scientific article

Hormone-sensitive lipase-knockout mice maintain high bone density during aging

scientific article

Hormone-sensitive lipase: control of intracellular tri-(di-)acylglycerol and cholesteryl ester hydrolysis

scientific article (publication date: October 2002)

Human BMP-7/OP-1 induces the growth and differentiation of adipocytes and osteoblasts in bone marrow stromal cell cultures.

scientific article

IL-17 regulates adipogenesis, glucose homeostasis, and obesity

scientific article

Interaction of hormone-sensitive lipase with steroidogenic acute regulatory protein: facilitation of cholesterol transfer in adrenal

scientific journal article

Interaction of rat hormone-sensitive lipase with adipocyte lipid-binding protein

scientific article

LDL and cAMP cooperate to regulate the functional expression of the LRP in rat ovarian granulosa cells

scientific article published on 23 August 2006

Lipid droplet metabolism

scientific article

Lipid droplets and steroidogenic cells.

scientific article published on 27 November 2015

MMSA-1 expression pattern in multiple myeloma and its clinical significance.

scientific article published on 22 October 2015

MicroRNAs 125a and 455 repress lipoprotein-supported steroidogenesis by targeting scavenger receptor class B type I in steroidogenic cells

scientific article

Microarray analysis of gene expression in liver, adipose tissue and skeletal muscle in response to chronic dietary administration of NDGA to high-fructose fed dyslipidemic rats

scientific article published on 29 September 2016

Mutational analysis of structural features of rat hormone-sensitive lipase.

scientific article published on June 1998

Mutational analysis of the "regulatory module" of hormone-sensitive lipase

scientific journal article

Nordihydroguaiaretic acid improves metabolic dysregulation and aberrant hepatic lipid metabolism in mice by both PPARα-dependent and -independent pathways

scientific article published on 25 October 2012

Novel ABCA1 peptide agonists with antidiabetic action

article

Overexpression of leptin in transgenic mice leads to decreased basal lipolysis, PKA activity, and perilipin levels

scientific article

Oxidative stress-induced inhibition of adrenal steroidogenesis requires participation of p38 mitogen-activated protein kinase signaling pathway.

scientific article

Regulation of expression and function of scavenger receptor class B, type I (SR-BI) by Na+/H+ exchanger regulatory factors (NHERFs)

scientific article published on 12 March 2013

Regulation of hormone-sensitive lipase in islets.

scientific article

SNARE-Mediated Cholesterol Movement to Mitochondria Supports Steroidogenesis in Rodent Cells

scientific article published on 15 January 2016

SNAREs and cholesterol movement for steroidogenesis

scientific article

Scavenger receptor B type 1: expression, molecular regulation, and cholesterol transport function

scholarly article by Wen-jun Shen et al published July 2018 in Journal of Lipid Research

Scavenger receptor class B type I (SR-BI): a versatile receptor with multiple functions and actions

scientific article published on 21 March 2014

Stimulation of Human Insulin Receptor Gene Expression by Retinoblastoma Gene Product ⬇️

scientific article published on September 1, 1995

Stimulation of lipolysis and hormone-sensitive lipase via the extracellular signal-regulated kinase pathway

scientific article (publication date: 30 November 2001)

The LDL receptor is not necessary for acute adrenal steroidogenesis in mouse adrenocortical cells

scientific article published on 19 September 2006

The proteome of cholesteryl-ester-enriched versus triacylglycerol-enriched lipid droplets

scientific article

Tissue-Specific Ablation of ACSL4 Results in Disturbed Steroidogenesis

scientific article published on 01 November 2019

Two glutamine synthetase genes from Phaseolus vulgaris L. display contrasting developmental and spatial patterns of expression in transgenic Lotus corniculatus plants

scientific article published in April 1989

Using SRM-MS to quantify nuclear protein abundance differences between adipose tissue depots of insulin-resistant mice.

scientific article published on 3 April 2015

Vimentin is a functional partner of hormone sensitive lipase and facilitates lipolysis

scientific article

p38 MAPK regulates steroidogenesis through transcriptional repression of STAR gene

scientific article

List of works by Wen-jun Shen

A Novel Role of Salt-Inducible Kinase 1 (SIK1) in the Post-Translational Regulation of Scavenger Receptor Class B Type 1 Activity.

ACTH Regulation of Adrenal SR-B1

Ablation of vimentin results in defective steroidogenesis

Adipocytes decrease Runx2 expression in osteoblastic cells: roles of PPARγ and adiponectin

Adipose Triglyceride Lipase, Not Hormone-Sensitive Lipase, Is the Primary Lipolytic Enzyme in Fasting Elephant Seals (Mirounga angustirostris).

Adrenal neutral cholesteryl ester hydrolase: identification, subcellular distribution, and sex differences

Age-related modulation of the effects of obesity on gene expression profiles of mouse bone marrow and epididymal adipocytes

Anti-Hyperlipidemic Effects of Synthetic Analogs of Nordihydroguaiaretic acid (NDGA) in Dyslipidemic Rats

Cardiac overexpression of hormone-sensitive lipase inhibits myocardial steatosis and fibrosis in streptozotocin diabetic mice

Cholesterol ester droplets and steroidogenesis

Creosote bush-derived NDGA attenuates molecular and pathological changes in a novel mouse model of non-alcoholic steatohepatitis (NASH)

Differential roles of cysteine residues in the cellular trafficking, dimerization, and function of the high-density lipoprotein receptor, SR-BI.

Effect of Creosote Bush-Derived NDGA on Expression of Genes Involved in Lipid Metabolism in Liver of High-Fructose Fed Rats: Relevance to NDGA Amelioration of Hypertriglyceridemia and Hepatic Steatosis

Effects of rosiglitazone and high fat diet on lipase/esterase expression in adipose tissue

Evidence for protein‐mediated fatty acid efflux by adipocytes ⬇️

Fat-specific protein 27 modulates nuclear factor of activated T cells 5 and the cellular response to stress

Fatty acid-binding protein-hormone-sensitive lipase interaction. Fatty acid dependence on binding.

Feedback inhibition of CREB signaling by p38 MAPK contributes to the negative regulation of steroidogenesis

Function of hormone-sensitive lipase in diacylglycerol-protein kinase C pathway

Functional analysis of the promoter region of a nodule-enhanced glutamine synthetase gene from Phaseolus vulgaris L

Functional interaction of hormone-sensitive lipase and perilipin in lipolysis

Gene expression profile of human skeletal muscle and adipose tissue of Chinese Han patients with type 2 diabetes mellitus

Generation of novel adipocyte monolayer cultures from embryonic stem cells

Hormonal regulation of microRNA expression in steroid producing cells of the ovary, testis and adrenal gland

Hormone-sensitive lipase functions as an oligomer

Hormone-sensitive lipase is required for high-density lipoprotein cholesteryl ester-supported adrenal steroidogenesis

Hormone-sensitive lipase knockouts

Hormone-sensitive lipase modulates adipose metabolism through PPARγ.

Hormone-sensitive lipase-knockout mice maintain high bone density during aging

Hormone-sensitive lipase: control of intracellular tri-(di-)acylglycerol and cholesteryl ester hydrolysis

Human BMP-7/OP-1 induces the growth and differentiation of adipocytes and osteoblasts in bone marrow stromal cell cultures.

IL-17 regulates adipogenesis, glucose homeostasis, and obesity

Interaction of hormone-sensitive lipase with steroidogenic acute regulatory protein: facilitation of cholesterol transfer in adrenal

Interaction of rat hormone-sensitive lipase with adipocyte lipid-binding protein

LDL and cAMP cooperate to regulate the functional expression of the LRP in rat ovarian granulosa cells

Lipid droplet metabolism

Lipid droplets and steroidogenic cells.

MMSA-1 expression pattern in multiple myeloma and its clinical significance.

MicroRNAs 125a and 455 repress lipoprotein-supported steroidogenesis by targeting scavenger receptor class B type I in steroidogenic cells

Microarray analysis of gene expression in liver, adipose tissue and skeletal muscle in response to chronic dietary administration of NDGA to high-fructose fed dyslipidemic rats

Mutational analysis of structural features of rat hormone-sensitive lipase.

Mutational analysis of the "regulatory module" of hormone-sensitive lipase

Nordihydroguaiaretic acid improves metabolic dysregulation and aberrant hepatic lipid metabolism in mice by both PPARα-dependent and -independent pathways

Novel ABCA1 peptide agonists with antidiabetic action

Overexpression of leptin in transgenic mice leads to decreased basal lipolysis, PKA activity, and perilipin levels

Oxidative stress-induced inhibition of adrenal steroidogenesis requires participation of p38 mitogen-activated protein kinase signaling pathway.

Regulation of expression and function of scavenger receptor class B, type I (SR-BI) by Na+/H+ exchanger regulatory factors (NHERFs)

Regulation of hormone-sensitive lipase in islets.

SNARE-Mediated Cholesterol Movement to Mitochondria Supports Steroidogenesis in Rodent Cells

SNAREs and cholesterol movement for steroidogenesis

Scavenger receptor B type 1: expression, molecular regulation, and cholesterol transport function

Scavenger receptor class B type I (SR-BI): a versatile receptor with multiple functions and actions

Stimulation of Human Insulin Receptor Gene Expression by Retinoblastoma Gene Product ⬇️

Stimulation of lipolysis and hormone-sensitive lipase via the extracellular signal-regulated kinase pathway

The LDL receptor is not necessary for acute adrenal steroidogenesis in mouse adrenocortical cells

The proteome of cholesteryl-ester-enriched versus triacylglycerol-enriched lipid droplets

Tissue-Specific Ablation of ACSL4 Results in Disturbed Steroidogenesis

Two glutamine synthetase genes from Phaseolus vulgaris L. display contrasting developmental and spatial patterns of expression in transgenic Lotus corniculatus plants

Using SRM-MS to quantify nuclear protein abundance differences between adipose tissue depots of insulin-resistant mice.

Vimentin is a functional partner of hormone sensitive lipase and facilitates lipolysis

p38 MAPK regulates steroidogenesis through transcriptional repression of STAR gene