List of works - Aaron Pollett

A descriptive analysis of gastric cancer specimen processing techniques ⬇️

scientific article published on March 1, 2011

A histology-based model for predicting microsatellite instability in colorectal cancers

scientific article published in December 2010

A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

scientific article (publication date: 4 January 2007)

A novel and rapid method of determining the effect of unclassified MLH1 genetic variants on differential allelic expression

scientific article

A novel complex mutation in MSH2 contributes to both Muir-Torre and Lynch Syndrome

scientific article published on 13 November 2009

ARID1A loss correlates with mismatch repair deficiency and intact p53 expression in high-grade endometrial carcinomas

scientific article

Café-au-lait macules and pediatric malignancy caused by biallelic mutations in the DNA mismatch repair (MMR) gene PMS2.

scientific article

Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers

scientific article

Comparison of clinical schemas and morphologic features in predicting Lynch syndrome in mutation-positive patients with endometrial cancer encountered in the context of familial gastrointestinal cancer registries.

scientific article published on 30 June 2011

Controlled Attenuation Parameter (CAP): a noninvasive method for the detection of hepatic steatosis based on transient elastography

article

Correlation of p53 Mutations in ThinPrep-Processed Fine Needle Breast Aspirates with Surgically Resected Breast Cancers

scientific article published on 01 November 2000

Digital pathology: Attitudes and practices in the Canadian pathology community

scientific article published on 14 March 2013

Discordance in fibrosis staging between liver biopsy and transient elastography using the FibroScan XL probe

scientific article published on 23 October 2011

Exacerbated tissue destruction in DSS-induced acute colitis of OPN-null mice is associated with downregulation of TNF-alpha expression and non-programmed cell death

scientific article (publication date: September 2006)

Feasibility and diagnostic performance of the FibroScan XL probe for liver stiffness measurement in overweight and obese patients

article

Gastrointestinal cancers and neurofibromatosis type 1 features in children with a germline homozygous MLH1 mutation

article

Genetic and clinical determinants of constitutional mismatch repair deficiency syndrome: report from the constitutional mismatch repair deficiency consortium

scientific article published on 15 January 2014

Genetic testing for Lynch syndrome in the province of Ontario.

scientific article published on 28 March 2016

Germline BRCA1 mutations predispose to pancreatic adenocarcinoma

scientific article published on 02 September 2008

Hepatic Adenomas Caused by Somatic HNF1A Mutations in Children With Biallelic Mismatch Repair Gene Mutations ⬇️

scientific article published on December 21, 2010

Hereditary nonpolyposis colorectal cancer--molecular basis

scientific article

High frequency of hereditary colorectal cancer in Newfoundland likely involves novel susceptibility genes.

scientific article published in October 2005

High prevalence of mismatch repair deficiency in prostate cancers diagnosed in mismatch repair gene mutation carriers from the colon cancer family registry

scientific article

High-grade papillary cystadenocarcinoma of the tongue.

scientific article published on August 1997

Identification of a novel MSH6 germline variant in a family with multiple gastro-intestinal malignancies by next generation sequencing.

scientific article

Identification of genes expressed by immune cells of the colon that are regulated by colorectal cancer-associated variants

scientific article

Improving the quality of processing gastric cancer specimens: The pathologist's perspective

scientific article published on 01 March 2010

Juvenile polyposis, hereditary hemorrhagic telangiectasia, and early onset colorectal cancer in patients with SMAD4 mutation

article

Lynch syndrome in a predominantly Afrocentric population: a clinicopathological and genetic study.

scientific article

Mucinous tumor of the appendix with limited peritoneal spread: is there a role for expectant observation?

scientific article published on 08 October 2013

Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation

scientific article published on 11 May 2016

Pathological features of colorectal carcinomas in MYH-associated polyposis

scientific article published on 28 June 2008

Pathology features in Bethesda guidelines predict colorectal cancer microsatellite instability: a population-based study

scientific article

Patients with Lynch syndrome mismatch repair gene mutations are at higher risk for not only upper tract urothelial cancer but also bladder cancer.

scientific article published on 2 August 2012

Performance characteristics of a brief Family History Questionnaire to screen for Lynch syndrome in women with newly diagnosed endometrial cancer.

scientific article published on 19 December 2014

Performance characteristics of screening strategies for Lynch syndrome in unselected women with newly diagnosed endometrial cancer who have undergone universal germline mutation testing.

scientific article published on 31 July 2014

Phenotypic and genotypic characterisation of biallelic mismatch repair deficiency (BMMR-D) syndrome

scientific article published on 13 April 2015

Plk4 haploinsufficiency causes mitotic infidelity and carcinogenesis

scientific article

Plk4 is required for cytokinesis and maintenance of chromosomal stability

scientific article

Prevalence of loss of expression of DNA mismatch repair proteins in primary epithelial ovarian tumors.

scientific article published in November 2012

Prognostic significance of mesenteric tumor nodules in patients with stage III colorectal cancer

scientific article published on January 2008

Progression and Management of Duodenal Neoplasia in Familial Adenomatous Polyposis

article

Promoter methylation of Wnt antagonistsDKK1andSFRP1is associated with opposing tumor subtypes in two large populations of colorectal cancer patients ⬇️

scientific article published on February 8, 2011

Promoter methylation of Wnt5a is associated with microsatellite instability and BRAF V600E mutation in two large populations of colorectal cancer patients ⬇️

scientific article published on May 17, 2011

Review of findings in prophylactic gynaecological specimens in Lynch syndrome with literature review and recommendations for grossing

scientific article published on 16 April 2014

Sclerosing pancreatitis presenting as a periampullary tumour

scientific article

Specific variants in the MLH1 gene region may drive DNA methylation, loss of protein expression, and MSI-H colorectal cancer

scientific article

The genetic basis of colorectal cancer in a population-based incident cohort with a high rate of familial disease

scientific article

The histomorphology of Lynch syndrome-associated ovarian carcinomas: toward a subtype-specific screening strategy

scientific article published on September 2014

The microenvironment-specific transformation of adult stem cells models malignant triton tumors

scientific article

Tumor microsatellite instability in early onset gastric cancer

scientific article published in October 2005

Unifying diagnosis for adenomatous polyps, café-au-lait macules, and a brain mass?

scientific article published on 24 September 2013

Use of mismatch repair immunohistochemistry and microsatellite instability testing: exploring Canadian practices.

scientific article

Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer

scientific article

Venous invasion in colorectal cancer: impact of an elastin stain on detection and interobserver agreement among gastrointestinal and nongastrointestinal pathologists

scientific article published in February 2013

List of works by Aaron Pollett

A descriptive analysis of gastric cancer specimen processing techniques ⬇️

A histology-based model for predicting microsatellite instability in colorectal cancers

A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

A novel and rapid method of determining the effect of unclassified MLH1 genetic variants on differential allelic expression

A novel complex mutation in MSH2 contributes to both Muir-Torre and Lynch Syndrome

ARID1A loss correlates with mismatch repair deficiency and intact p53 expression in high-grade endometrial carcinomas

Café-au-lait macules and pediatric malignancy caused by biallelic mutations in the DNA mismatch repair (MMR) gene PMS2.

Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers

Comparison of clinical schemas and morphologic features in predicting Lynch syndrome in mutation-positive patients with endometrial cancer encountered in the context of familial gastrointestinal cancer registries.

Controlled Attenuation Parameter (CAP): a noninvasive method for the detection of hepatic steatosis based on transient elastography

Correlation of p53 Mutations in ThinPrep-Processed Fine Needle Breast Aspirates with Surgically Resected Breast Cancers

Digital pathology: Attitudes and practices in the Canadian pathology community

Discordance in fibrosis staging between liver biopsy and transient elastography using the FibroScan XL probe

Exacerbated tissue destruction in DSS-induced acute colitis of OPN-null mice is associated with downregulation of TNF-alpha expression and non-programmed cell death

Feasibility and diagnostic performance of the FibroScan XL probe for liver stiffness measurement in overweight and obese patients

Gastrointestinal cancers and neurofibromatosis type 1 features in children with a germline homozygous MLH1 mutation

Genetic and clinical determinants of constitutional mismatch repair deficiency syndrome: report from the constitutional mismatch repair deficiency consortium

Genetic testing for Lynch syndrome in the province of Ontario.

Germline BRCA1 mutations predispose to pancreatic adenocarcinoma

Hepatic Adenomas Caused by Somatic HNF1A Mutations in Children With Biallelic Mismatch Repair Gene Mutations ⬇️

Hereditary nonpolyposis colorectal cancer--molecular basis

High frequency of hereditary colorectal cancer in Newfoundland likely involves novel susceptibility genes.

High prevalence of mismatch repair deficiency in prostate cancers diagnosed in mismatch repair gene mutation carriers from the colon cancer family registry

High-grade papillary cystadenocarcinoma of the tongue.

Identification of a novel MSH6 germline variant in a family with multiple gastro-intestinal malignancies by next generation sequencing.

Identification of genes expressed by immune cells of the colon that are regulated by colorectal cancer-associated variants

Improving the quality of processing gastric cancer specimens: The pathologist's perspective

Juvenile polyposis, hereditary hemorrhagic telangiectasia, and early onset colorectal cancer in patients with SMAD4 mutation

Lynch syndrome in a predominantly Afrocentric population: a clinicopathological and genetic study.

Mucinous tumor of the appendix with limited peritoneal spread: is there a role for expectant observation?

Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation

Pathological features of colorectal carcinomas in MYH-associated polyposis

Pathology features in Bethesda guidelines predict colorectal cancer microsatellite instability: a population-based study

Patients with Lynch syndrome mismatch repair gene mutations are at higher risk for not only upper tract urothelial cancer but also bladder cancer.

Performance characteristics of a brief Family History Questionnaire to screen for Lynch syndrome in women with newly diagnosed endometrial cancer.

Performance characteristics of screening strategies for Lynch syndrome in unselected women with newly diagnosed endometrial cancer who have undergone universal germline mutation testing.

Phenotypic and genotypic characterisation of biallelic mismatch repair deficiency (BMMR-D) syndrome

Plk4 haploinsufficiency causes mitotic infidelity and carcinogenesis

Plk4 is required for cytokinesis and maintenance of chromosomal stability

Prevalence of loss of expression of DNA mismatch repair proteins in primary epithelial ovarian tumors.

Prognostic significance of mesenteric tumor nodules in patients with stage III colorectal cancer

Progression and Management of Duodenal Neoplasia in Familial Adenomatous Polyposis

Promoter methylation of Wnt antagonistsDKK1andSFRP1is associated with opposing tumor subtypes in two large populations of colorectal cancer patients ⬇️

Promoter methylation of Wnt5a is associated with microsatellite instability and BRAF V600E mutation in two large populations of colorectal cancer patients ⬇️

Review of findings in prophylactic gynaecological specimens in Lynch syndrome with literature review and recommendations for grossing

Sclerosing pancreatitis presenting as a periampullary tumour

Specific variants in the MLH1 gene region may drive DNA methylation, loss of protein expression, and MSI-H colorectal cancer

The genetic basis of colorectal cancer in a population-based incident cohort with a high rate of familial disease

The histomorphology of Lynch syndrome-associated ovarian carcinomas: toward a subtype-specific screening strategy

The microenvironment-specific transformation of adult stem cells models malignant triton tumors

Tumor microsatellite instability in early onset gastric cancer

Unifying diagnosis for adenomatous polyps, café-au-lait macules, and a brain mass?

Use of mismatch repair immunohistochemistry and microsatellite instability testing: exploring Canadian practices.

Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer

Venous invasion in colorectal cancer: impact of an elastin stain on detection and interobserver agreement among gastrointestinal and nongastrointestinal pathologists