List of works - Laurent Journot

A systems-level approach to parental genomic imprinting: the imprinted gene network includes extracellular matrix genes and regulates cell cycle exit and differentiation

scientific article

Alkaline fixation drastically improves the signal of in situ hybridization.

scientific article published on May 2000

An islet activating protein-sensitive G protein is involved in dopamine inhibition of angiotensin and thyrotropin-releasing hormone-stimulated inositol phosphate production in anterior pituitary cells

scientific article published in November 1987

Cerebral Cortex Generated from Pluripotent Stem Cells to Model Corticogenesis and Rebuild Cortical Circuits: In Vitro Veritas?

scientific article published on 20 February 2019

Chapter II Brain PACAP/VIP receptors: regional distribution, functional properties and physiological relevance

Characterization of the methylation-sensitive promoter of the imprinted ZAC gene supports its role in transient neonatal diabetes mellitus

scientific article published on 10 April 2001

Concomitant induction of apoptosis and necrosis in cerebellar granule cells following serum and potassium withdrawal.

scientific article

Deletion within the amino-terminal region of Gs alpha impairs its ability to interact with beta gamma subunits and to activate adenylate cyclase.

scientific article

Differential expression of pituitary adenylate cyclase-activating polypeptide/vasoactive intestinal polypeptide receptor subtypes in clonal pituitary somatotrophs and gonadotrophs

scientific article published on 01 May 1995

Differential signal transduction by five splice variants of the PACAP receptor

scientific journal article

Differential signal transduction by six splice variants of the pituitary adenylate cyclase-activating peptide (PACAP) receptor.

scientific article published on February 1995

Dissociation between light-induced phase shift of the circadian rhythm and clock gene expression in mice lacking the pituitary adenylate cyclase activating polypeptide type 1 receptor.

scientific article

Do recombinant receptor assays provide affinity and potency estimates?

scientific article published on May 1997

DoubleMyodandIgf2inactivation promotes brown adipose tissue development by increasingPrdm16expression ⬇️

scientific article published on August 2, 2012

Essential requirement for β-arrestin2 in mouse intestinal tumors with elevated Wnt signaling ⬇️

scientific article published on February 6, 2012

Evolution of gene expression after whole-genome duplication: New insights from the spotted gar genome.

scientific article

Expression at the imprinted dlk1-gtl2 locus is regulated by proneural genes in the developing telencephalon

scientific article

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database

scientific article

Genome-wide profiling of G protein-coupled receptors in cerebellar granule neurons using high-throughput, real-time PCR ⬇️

scientific article

H19 acts as a trans regulator of the imprinted gene network controlling growth in mice

scientific journal article

High-salt-recovered sequences are associated with the active chromosomal compartment and with large ribonucleoprotein complexes including nuclear bodies

article

ICR noncoding RNA expression controls imprinting and DNA replication at the Dlk1-Dio3 domain.

scientific article published on 25 September 2014

ISoLDE: a data-driven statistical method for the inference of allelic imbalance in datasets with reciprocal crosses

scientific article published on 01 January 2020

Identification of Plagl1/Zac1 binding sites and target genes establishes its role in the regulation of extracellular matrix genes and the imprinted gene network

scientific article published on 29 July 2017

Identification of potential pharmacological targets by analysis of the comprehensive G protein-coupled receptor repertoire in the four cardiac chambers.

scientific article published on 19 February 2009

Identification of the master sex determining gene in Northern pike (Esox lucius) reveals restricted sex chromosome differentiation

scientific article published on 22 August 2019

In Vitro Corticogenesis from Embryonic Stem Cells Recapitulates the In Vivo Epigenetic Control of Imprinted Gene Expression.

scientific article published on 19 April 2016

In vitro fertilization and embryo culture strongly impact the placental transcriptome in the mouse model

scientific article

Induction of the PAC1-R (PACAP-type I receptor) gene by p53 and Zac.

scientific article

Induction of type I PACAP receptor expression by the new zinc finger protein Zac1 and p53

scientific article published on 01 December 1998

International Union of Pharmacology. XVIII. Nomenclature of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide.

scientific article published in June 1998

Loss of expression of the candidate tumor suppressor gene ZAC in breast cancer cell lines and primary tumors

article

Modulation of imprinted gene network in placenta results in normal development of in vitro manipulated mouse embryos.

scientific article published on 11 February 2010

Mouse Parthenogenetic Embryonic Stem Cells with Biparental-Like Expression of Imprinted Genes Generate Cortical-Like Neurons That Integrate into the Injured Adult Cerebral Cortex

scientific article

Mutation of valine residue unique to alpha subunit of Gs abolishes activation

scientific article published on 01 August 1994

PACAP-38 protects cerebellar granule cells from apoptosis

scientific article

Phosphorylation of bid by casein kinases I and II regulates its cleavage by caspase 8.

scientific article

Pituitary adenylate cyclase-activating polypeptide (PACAP-38) protects cerebellar granule neurons from apoptosis by activating the mitogen-activated protein kinase (MAP kinase) pathway.

scientific article published in January 1997

Reconstitution of cyc- S49 membranes by in vitro translated Gs alpha. Membrane anchorage and functional implications

scientific article published on 01 July 1989

Second messengers associated with the action of AII and dopamine D2 receptors in anterior pituitary. Relationship with prolactin secretion

scientific article

Stimulation of the ERK pathway by GTP-loaded Rap1 requires the concomitant activation of Ras, protein kinase C, and protein kinase A in neuronal cells

scientific journal article

The candidate tumor suppressor gene ZAC is involved in keratinocyte differentiation and its expression is lost in basal cell carcinomas

scientific article published on September 2005

The expression of the antiproliferative gene ZAC is lost or highly reduced in nonfunctioning pituitary adenomas.

scientific article published in December 2000

The genome of the arapaima (Arapaima gigas) provides insights into gigantism, fast growth and chromosomal sex determination system

scientific article published on 28 March 2019

The sterlet sturgeon genome sequence and the mechanisms of segmental rediploidization

scientific article published on 30 March 2020

TopoFun: a machine learning method to improve the functional similarity of gene co-expression modules

scientific article published on 08 November 2021

Viral induction of Zac1b through TLR3- and IRF3-dependent pathways.

scientific article published on 13 October 2010

What makes a bad egg? Egg transcriptome reveals dysregulation of translational machinery and novel fertility genes important for fertilization

scientific article published on 15 July 2019

Zac1 Regulates the Differentiation and Migration of Neocortical Neurons via Pac1.

scientific article published on September 2015

Zac1 functions through TGFbetaII to negatively regulate cell number in the developing retina.

scientific article published on 8 June 2007

Zac1 is up-regulated in neural cells of the limbic system of mouse brain following seizures that provoke strong cell activation

scientific article published in January 2004

Zac1 regulates an imprinted gene network critically involved in the control of embryonic growth

scientific article published on November 2006

hZAC encodes a zinc finger protein with antiproliferative properties and maps to a chromosomal region frequently lost in cancer

scientific article

List of works by Laurent Journot

A systems-level approach to parental genomic imprinting: the imprinted gene network includes extracellular matrix genes and regulates cell cycle exit and differentiation

Alkaline fixation drastically improves the signal of in situ hybridization.

An islet activating protein-sensitive G protein is involved in dopamine inhibition of angiotensin and thyrotropin-releasing hormone-stimulated inositol phosphate production in anterior pituitary cells

Cerebral Cortex Generated from Pluripotent Stem Cells to Model Corticogenesis and Rebuild Cortical Circuits: In Vitro Veritas?

Chapter II Brain PACAP/VIP receptors: regional distribution, functional properties and physiological relevance

Characterization of the methylation-sensitive promoter of the imprinted ZAC gene supports its role in transient neonatal diabetes mellitus

Concomitant induction of apoptosis and necrosis in cerebellar granule cells following serum and potassium withdrawal.

Deletion within the amino-terminal region of Gs alpha impairs its ability to interact with beta gamma subunits and to activate adenylate cyclase.

Differential expression of pituitary adenylate cyclase-activating polypeptide/vasoactive intestinal polypeptide receptor subtypes in clonal pituitary somatotrophs and gonadotrophs

Differential signal transduction by five splice variants of the PACAP receptor

Differential signal transduction by six splice variants of the pituitary adenylate cyclase-activating peptide (PACAP) receptor.

Dissociation between light-induced phase shift of the circadian rhythm and clock gene expression in mice lacking the pituitary adenylate cyclase activating polypeptide type 1 receptor.

Do recombinant receptor assays provide affinity and potency estimates?

DoubleMyodandIgf2inactivation promotes brown adipose tissue development by increasingPrdm16expression ⬇️

Essential requirement for β-arrestin2 in mouse intestinal tumors with elevated Wnt signaling ⬇️

Evolution of gene expression after whole-genome duplication: New insights from the spotted gar genome.

Expression at the imprinted dlk1-gtl2 locus is regulated by proneural genes in the developing telencephalon

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database

Genome-wide profiling of G protein-coupled receptors in cerebellar granule neurons using high-throughput, real-time PCR ⬇️

H19 acts as a trans regulator of the imprinted gene network controlling growth in mice

High-salt-recovered sequences are associated with the active chromosomal compartment and with large ribonucleoprotein complexes including nuclear bodies

ICR noncoding RNA expression controls imprinting and DNA replication at the Dlk1-Dio3 domain.

ISoLDE: a data-driven statistical method for the inference of allelic imbalance in datasets with reciprocal crosses

Identification of Plagl1/Zac1 binding sites and target genes establishes its role in the regulation of extracellular matrix genes and the imprinted gene network

Identification of potential pharmacological targets by analysis of the comprehensive G protein-coupled receptor repertoire in the four cardiac chambers.

Identification of the master sex determining gene in Northern pike (Esox lucius) reveals restricted sex chromosome differentiation

In Vitro Corticogenesis from Embryonic Stem Cells Recapitulates the In Vivo Epigenetic Control of Imprinted Gene Expression.

In vitro fertilization and embryo culture strongly impact the placental transcriptome in the mouse model

Induction of the PAC1-R (PACAP-type I receptor) gene by p53 and Zac.

Induction of type I PACAP receptor expression by the new zinc finger protein Zac1 and p53

International Union of Pharmacology. XVIII. Nomenclature of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide.

Loss of expression of the candidate tumor suppressor gene ZAC in breast cancer cell lines and primary tumors

Modulation of imprinted gene network in placenta results in normal development of in vitro manipulated mouse embryos.

Mouse Parthenogenetic Embryonic Stem Cells with Biparental-Like Expression of Imprinted Genes Generate Cortical-Like Neurons That Integrate into the Injured Adult Cerebral Cortex

Mutation of valine residue unique to alpha subunit of Gs abolishes activation

PACAP-38 protects cerebellar granule cells from apoptosis

Phosphorylation of bid by casein kinases I and II regulates its cleavage by caspase 8.

Pituitary adenylate cyclase-activating polypeptide (PACAP-38) protects cerebellar granule neurons from apoptosis by activating the mitogen-activated protein kinase (MAP kinase) pathway.

Reconstitution of cyc- S49 membranes by in vitro translated Gs alpha. Membrane anchorage and functional implications

Second messengers associated with the action of AII and dopamine D2 receptors in anterior pituitary. Relationship with prolactin secretion

Stimulation of the ERK pathway by GTP-loaded Rap1 requires the concomitant activation of Ras, protein kinase C, and protein kinase A in neuronal cells

The candidate tumor suppressor gene ZAC is involved in keratinocyte differentiation and its expression is lost in basal cell carcinomas

The expression of the antiproliferative gene ZAC is lost or highly reduced in nonfunctioning pituitary adenomas.

The genome of the arapaima (Arapaima gigas) provides insights into gigantism, fast growth and chromosomal sex determination system

The sterlet sturgeon genome sequence and the mechanisms of segmental rediploidization

TopoFun: a machine learning method to improve the functional similarity of gene co-expression modules

Viral induction of Zac1b through TLR3- and IRF3-dependent pathways.

What makes a bad egg? Egg transcriptome reveals dysregulation of translational machinery and novel fertility genes important for fertilization

Zac1 Regulates the Differentiation and Migration of Neocortical Neurons via Pac1.

Zac1 functions through TGFbetaII to negatively regulate cell number in the developing retina.

Zac1 is up-regulated in neural cells of the limbic system of mouse brain following seizures that provoke strong cell activation

Zac1 regulates an imprinted gene network critically involved in the control of embryonic growth

hZAC encodes a zinc finger protein with antiproliferative properties and maps to a chromosomal region frequently lost in cancer