List of works by Virginia Espina

A Randomized Phase II Preoperative Study of Autophagy Inhibition With High-Dose Hydroxychloroquine and Gemcitabine/Nab-Paclitaxel in Pancreatic Cancer Patients

scientific article published on 10 March 2020

A novel biomarker harvesting nanotechnology identifies Bak as a candidate melanoma biomarker in serum

scientific article published on January 2011

A phase II and pharmacodynamic study of gefitinib in patients with refractory or recurrent epithelial ovarian cancer

scientific article published on April 2007

A portrait of tissue phosphoprotein stability in the clinical tissue procurement process

scientific article published on 30 July 2008

A prospective analysis of imatinib-induced c-kit modulation in ovarian cancer

scientific article published on 01 July 2007

A transforming growth factor-beta receptor-interacting protein frequently mutated in human ovarian cancer

scientific article

Accurate diagnosis of acute graft-versus-host disease using serum proteomic pattern analysis

scientific article

Activated VEGF receptor shed into the vitreous in eyes with wet AMD: a new class of biomarkers in the vitreous with potential for predicting the treatment timing and monitoring response

scientific article published on May 2009

Adipocyte-derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment

scientific article

Adipocyte-derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment

Application of laser capture microdissection and protein microarray technologies in the molecular analysis of airway injury following pollution particle exposure

scientific article

Application of laser microdissection and reverse-phase protein microarrays to the molecular profiling of cancer signal pathway networks in the tissue microenvironment

scientific article

Attacking breast cancer at the preinvasion stage by targeting autophagy

scientific article published on March 2013

Biomarkers of ovarian tumours

scientific article

CSF proteome: a protein repository for potential biomarker identification

scientific article

Chemokine-Releasing Microparticles Improve Bacterial Clearance and Survival of Anthrax Spore-Challenged Mice

scientific article

Clinical proteomics: revolutionizing disease detection and patient tailoring therapy

scientific article

Comparison of global versus epidermal growth factor receptor pathway profiling for prediction of lapatinib sensitivity in bladder cancer

scientific article

Core-shell hydrogel particles harvest, concentrate and preserve labile low abundance biomarkers

scientific article

Current state of the art for enhancing urine biomarker discovery

scientific article

Effects of HER family-targeting tyrosine kinase inhibitors on antibody-dependent cell-mediated cytotoxicity in HER2-expressing breast cancer

scientific article published on 29 October 2020

Elevated TNFR1 and serotonin in bone metastasis are correlated with poor survival following bone metastasis diagnosis for both carcinoma and sarcoma primary tumors

scientific article

Expression of xeroderma pigmentosum A protein predicts improved outcome in metastatic ovarian carcinoma

scientific article published on 01 June 2005

Functional protein network activation mapping reveals new potential molecular drug targets for poor prognosis pediatric BCP-ALL

scientific article

Genomic and proteomic technologies for individualisation and improvement of cancer treatment

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Hydrogel nanoparticle harvesting of plasma or urine for detecting low abundance proteins

scientific article published on 7 August 2014

Inhibition of histone deacetylase 4 increases cytotoxicity of docetaxel in gastric cancer cells

scientific article

Laser capture microdissection and protein microarray analysis of human non-small cell lung cancer: differential epidermal growth factor receptor (EGPR) phosphorylation events associated with mutated EGFR compared with wild type

scientific article

Laser capture microdissection technology

scientific article

Laser capture microdissection: Arcturus(XT) infrared capture and UV cutting methods

scientific article

Laser-capture microdissection

scientific article published on 01 January 2006

Malignant precursor cells pre-exist in human breast DCIS and require autophagy for survival

scientific article

Manual exfoliation of fresh tissue obviates the need for frozen sections for molecular profiling

scientific article

Mapping molecular networks using proteomics: a vision for patient-tailored combination therapy.

scientific article

Mapping protein signal pathway interaction in sarcoma bone metastasis: linkage between rank, metalloproteinases turnover and growth factor signaling pathways.

scientific article published on 23 July 2013

Molecular analysis of HER2 signaling in human breast cancer by functional protein pathway activation mapping

scientific article

Molecular network analysis using reverse phase protein microarrays for patient tailored therapy

scientific article published on January 2008

Multiplexed cell signaling analysis of human breast cancer applications for personalized therapy

scientific article

Nanoparticle technology: Addressing the fundamental roadblocks to protein biomarker discovery.

scientific article published in August 2009

Nanoparticle technology: amplifying the effective sensitivity of biomarker detection to create a urine test for hGH.

scientific article published on September 2009

Nitric oxide as a regulator of B. anthracis pathogenicity

scientific article

Non-enzymatic, serum-free tissue culture of pre-invasive breast lesions for spontaneous generation of mammospheres

scientific article

One-step preservation of phosphoproteins and tissue morphology at room temperature for diagnostic and research specimens

scientific article

PMCA2 regulates HER2 protein kinase localization and signaling and promotes HER2-mediated breast cancer

scientific article

Pathologic complete response after preoperative anti-HER2 therapy correlates with alterations in PTEN, FOXO, phosphorylated Stat5, and autophagy protein signaling.

scientific article

Pathology of the future: molecular profiling for targeted therapy

scientific article

Pegylated, steptavidin-conjugated quantum dots are effective detection elements for reverse-phase protein microarrays

scientific article

Persistent CD49d engagement in circulating CLL cells: a role for blood-borne ligands?

scientific article published on 19 June 2015

Phosphoprotein pathway mapping: Akt/mammalian target of rapamycin activation is negatively associated with childhood rhabdomyosarcoma survival

scientific article published in April 2007

Phosphoprotein stability in clinical tissue and its relevance for reverse phase protein microarray technology

scientific article

Physicochemically modified silicon as a substrate for protein microarrays

scientific article published on 20 September 2006

Protein biomarkers for subtyping breast cancer and implications for future research.

scientific article published on 22 December 2017

Protein microarray detection strategies: focus on direct detection technologies

scientific article published in July 2004

Protein microarrays: meeting analytical challenges for clinical applications.

scientific article

Protein microarrays: molecular profiling technologies for clinical specimens

scientific article published on November 2003

Protein painting reveals solvent-excluded drug targets hidden within native protein-protein interfaces.

scientific article

Protein pathway analysis in Clinical Proteomics using protein microarrays.

scientific article

Proteomic analysis of apoptotic pathways reveals prognostic factors in follicular lymphoma

scientific article

Proteomic profiling of the NCI-60 cancer cell lines using new high-density reverse-phase lysate microarrays

scientific article

Proteomics for cancer drug design

scientific article published on 04 August 2019

Quantitative cell signalling analysis reveals down-regulation of MAPK pathway activation in colorectal cancer

scientific article

Reduction of preanalytical variability in specimen procurement for molecular profiling

scientific article published on January 2012

Reverse phase protein arrays: mapping the path towards personalized medicine.

scientific article published on December 2014

Reverse phase protein microarrays advance to use in clinical trials

scientific article

Reverse phase protein microarrays: fluorometric and colorimetric detection.

scientific article published in January 2011

Reverse-Phase Microarray Analysis Reveals Novel Targets in Lymph Nodes of Bacillus anthracis Spore-Challenged Mice

scientific article published on 19 June 2015

Reverse-phase phosphoproteome analysis of signaling pathways induced by Rift valley fever virus in human small airway epithelial cells

scientific article

Reverse-phase protein microarrays for theranostics and patient tailored therapy

scientific article

Reverse-phase protein microarrays: application to biomarker discovery and translational medicine.

scientific article published on September 2007

Role of proteomics in personalized medicine

scientific article published on 01 August 2006

Safety and Biologic Response of Pre-operative Autophagy Inhibition in Combination with Gemcitabine in Patients with Pancreatic Adenocarcinoma

scientific article

Serum proteomics in cancer diagnosis and management.

scientific article published on January 2004

Stratification of clear cell renal cell carcinoma by signaling pathway analysis

scientific article

Students who demonstrate strong talent and interest in STEM are initially attracted to STEM through extracurricular experiences

scientific article

The heme degradation pathway is a promising serum biomarker source for the early detection of Alzheimer's disease

scientific article published on January 2010

Tissue is alive: New technologies are needed to address the problems of protein biomarker pre-analytical variability

scientific article

Treatment and Long-Term Risks for Patients With a Diagnosis of Ductal Carcinoma In Situ

scientific article published on 01 March 2016

Tumorigenic and metastatic activity of human thyroid cancer stem cells.

scientific article published on 19 October 2010

Use of proteomic analysis to monitor responses to biological therapies

scientific article

Use of proteomic patterns to screen for gastrointestinal malignancies.

scientific article published on March 2004

Use of reverse phase protein microarrays and reference standard development for molecular network analysis of metastatic ovarian carcinoma.

scientific article

Whole proteome analysis of mouse lymph nodes in cutaneous anthrax

scientific article

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