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List of works by Guangjun Nie

"Triple-punch" strategy for triple negative breast cancer therapy with minimized drug dosage and improved antitumor efficacy

scientific article published on 26 January 2015

5-aza-2'-deoxycytidine activates iron uptake and heme biosynthesis by increasing c-Myc nuclear localization and binding to the E-boxes of transferrin receptor 1 (TfR1) and ferrochelatase (Fech) genes.

scientific article

A Bioinspired Nanoprobe with Multilevel Responsive T1 -Weighted MR Signal-Amplification Illuminates Ultrasmall Metastases

scientific article published on 04 December 2019

A Chinese family carrying novel mutations in SEC23B and HFE2, the genes responsible for congenital dyserythropoietic anaemia II (CDA II) and primary iron overload, respectively

article

A DNA nanodevice-based vaccine for cancer immunotherapy

scientific article published on 07 September 2020

A Graphdiyne Oxide-Based Iron Sponge with Photothermally Enhanced Tumor-Specific Fenton Chemistry

scientific article published on 28 June 2020

A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy.

scientific article published on 15 December 2013

A membrane vesicle-based dual vaccine against melanoma and Lewis lung carcinoma

scientific article published on 06 June 2012

A new human catalytic antibody Se-scFv-2D8 and its selenium-containing single domains with high GPX activity

scientific article

A superparamagnetic Fe3O4-loaded polymeric nanocarrier for targeted delivery of evodiamine with enhanced antitumor efficacy

scientific article published on 16 May 2013

Amphiphilic hyper-branched co-polymer nanoparticles for the controlled delivery of anti-tumor agents

scientific article published on October 2010

An Extendable Star-Like Nanoplatform for Functional and Anatomical Imaging-Guided Photothermal Oncotherapy

scientific article published on 26 March 2019

An MMP-2 Responsive Liposome Integrating Antifibrosis and Chemotherapeutic Drugs for Enhanced Drug Perfusion and Efficacy in Pancreatic Cancer

scientific article published on 13 January 2016

An injectable hexapeptide hydrogel for localized chemotherapy prevents breast cancer recurrence.

scientific article

Announcing the 2019 ACS Nano Award Lecture Laureates

scientific article published on 01 May 2019

Anticancer Activities of Tumor-killing Nanorobots

scientific article published on 28 February 2019

Antineoplastic activities of Gd@C₈₂(OH)₂₂ nanoparticles: tumor microenvironment regulation

scientific article published on 31 October 2012

Applications of nanomaterials as vaccine adjuvants

scientific article

Aspect ratios of gold nanoshell capsules mediated melanoma ablation by synergistic photothermal therapy and chemotherapy.

scientific article published on 19 December 2015

Assessment of the Biological Effects of a Multifunctional Nano-Drug-Carrier and Its Encapsulated Drugs

scientific article published on 4 November 2015

Bacterial Outer Membrane Vesicles Presenting Programmed Death 1 for Improved Cancer Immunotherapy via Immune Activation and Checkpoint Inhibition

scientific article published on 24 November 2020

Bioengineered bacteria-derived outer membrane vesicles as a versatile antigen display platform for tumor vaccination via Plug-and-Display technology

scientific article published on 06 April 2021

Biomimetic Metal-Organic Framework Nanoparticles for Cooperative Combination of Antiangiogenesis and Photodynamic Therapy for Enhanced Efficacy

scientific article published on 18 February 2019

Biosafety assessment of Gd@C82(OH)22 nanoparticles on Caenorhabditis elegans.

scientific article published on 3 May 2011

Blood-triggered generation of platinum nanoparticle functions as an anti-cancer agent

scientific article published on 28 January 2020

Both Nramp1 and DMT1 are necessary for efficient macrophage iron recycling

scientific article published on 13 April 2010

Cancer Cell-derived Exosomes Induce Mitogen-activated Protein Kinase-dependent Monocyte Survival by Transport of Functional Receptor Tyrosine Kinases.

scientific article published on 19 February 2016

Cell-Penetrating Nanoparticles Activate the Inflammasome to Enhance Antibody Production by Targeting Microtubule-Associated Protein 1-Light Chain 3 for Degradation

scientific article published on 20 February 2020

Chaperonin-GroEL as a Smart Hydrophobic Drug Delivery and Tumor Targeting Molecular Machine for Tumor Therapy.

scientific article published on 29 December 2017

Chirality of glutathione surface coating affects the cytotoxicity of quantum dots

scientific article published on 12 May 2011

Co-delivery of HIF1α siRNA and gemcitabine via biocompatible lipid-polymer hybrid nanoparticles for effective treatment of pancreatic cancer

scientific article

Co-delivery strategies based on multifunctional nanocarriers for cancer therapy.

scientific article published on October 2012

Combination of tumour-infarction therapy and chemotherapy via the co-delivery of doxorubicin and thrombin encapsulated in tumour-targeted nanoparticles

scientific article published on 22 June 2020

Controlling assembly of paired gold clusters within apoferritin nanoreactor for in vivo kidney targeting and biomedical imaging

scientific article published on 17 May 2011

Cooperatively Responsive Peptide Nanotherapeutic that Regulates Angiopoietin Receptor Tie2 Activity in Tumor Microenvironment To Prevent Breast Tumor Relapse after Chemotherapy

scientific article published on 22 April 2019

Correction to Cooperatively Responsive Peptide Nanotherapeutic that Regulates Angiopoietin Receptor Tie2 Activity in Tumor Microenvironment To Prevent Breast Tumor Relapse after Chemotherapy

scientific article published on 11 September 2019

Correction to Targeted Co-delivery of the Iron Chelator Deferoxamine and a HIF1α Inhibitor Impairs Pancreatic Tumor Growth

scientific article published on 13 January 2020

Deciphering the underlying mechanisms of oxidation-state dependent cytotoxicity of graphene oxide on mammalian cells.

scientific article published on 3 June 2015

Designing Liposomes To Suppress Extracellular Matrix Expression To Enhance Drug Penetration and Pancreatic Tumor Therapy

scientific article published on 14 August 2017

Development of a Cancer Vaccine Using In Vivo Click‐Chemistry‐Mediated Active Lymph Node Accumulation for Improved Immunotherapy

scientific article published in 2021

Direct evidence for catalase and peroxidase activities of ferritin–platinum nanoparticles

article

Distinct effects of tea catechins on 6-hydroxydopamine-induced apoptosis in PC12 cells

scientific article published in January 2002

Dopamine Delivery via pH-Sensitive Nanoparticles for Tumor Blood Vessel Normalization and an Improved Effect of Cancer Chemotherapeutic Drugs

scientific article published on 05 August 2019

Effects of gestational age and surface modification on materno-fetal transfer of nanoparticles in murine pregnancy

scientific article

Effects of nanoparticle size and gestational age on maternal biodistribution and toxicity of gold nanoparticles in pregnant mice

scientific article

Energy metabolism analysis reveals the mechanism of inhibition of breast cancer cell metastasis by PEG-modified graphene oxide nanosheets

scientific article published on 08 September 2014

Engineered Nanoplatelets for Targeted Delivery of Plasminogen Activators to Reverse Thrombus in Multiple Mouse Thrombosis Models

scientific article published on 01 December 2019

Engineering Biomimetic Platesomes for pH-Responsive Drug Delivery and Enhanced Antitumor Activity

scientific article published on 20 June 2019

Engineering the assemblies of biomaterial nanocarriers for delivery of multiple theranostic agents with enhanced antitumor efficacy

scientific article published on 22 January 2013

Enhanced Natural Killer Cell Immunotherapy by Rationally Assembling Fc Fragments of Antibodies onto Tumor Membranes

scientific article published on 14 December 2018

Enhanced anti-tumor efficacy by co-delivery of doxorubicin and paclitaxel with amphiphilic methoxy PEG-PLGA copolymer nanoparticles ⬇️

scientific article published on July 31, 2011

Epidermal Growth Factor Receptor-Targeting Peptide Nanoparticles Simultaneously Deliver Gemcitabine and Olaparib To Treat Pancreatic Cancer with Breast Cancer 2 ( BRCA2) Mutation

scientific article published on 12 November 2018

Excessive iron and weightlessness effects on the femurs and livers of rats.

scientific article published in January 2015

Exosomes as Extrapulmonary Signaling Conveyors for Nanoparticle-Induced Systemic Immune Activation

scientific article published on 06 December 2011

Facet-Mediated Photodegradation of Organic Dye over Hematite Architectures by Visible Light

article

Facile Synthesis of pH-sensitive Germanium Nanocrystals with High Quantum Yield for Intracellular Acidic Compartment Imaging

scientific article

Ferritin-based nanoprobes: promising materials for tumor imaging

scientific article

Ferroportin1 deficiency in mouse macrophages impairs iron homeostasis and inflammatory responses

article

Field-Free Isolation of Exosomes from Extracellular Vesicles by Microfluidic Viscoelastic Flows

scientific article

Fine-tuned h-ferritin nanocage with multiple gold clusters as near-infrared kidney specific targeting nanoprobe.

scientific article

Functional Analysis of GLRX5 Mutants Reveals Distinct Functionalities of GLRX5 Protein.

scientific article

Functional consequences of the human DMT1 (SLC11A2) mutation on protein expression and iron uptake

scientific article published on 9 August 2005

Hepcidin levels in hyperprolactinemic women monitored by nanopore thin film based assay: Correlation with pregnancy-associated hormone prolactin

scientific article published on 04 February 2015

Heterozygous missense mutations in the GLRX5 gene cause sideroblastic anemia in a Chinese patient

article

How can nanotechnology help membrane vesicle-based cancer immunotherapy development?

scientific article published on 29 October 2012

Identification of a novel UROS mutation in a Chinese patient affected by congenital erythropoietic porphyria

scientific article

Identification of four SLC19A2 mutations in four Chinese thiamine responsive megaloblastic anemia patients without diabetes

scientific article published on 16 December 2013

Identification of two novel PBGD mutations in acute intermittent porphyria patients accompanying anemia in mainland China

article

Impact of PEGylation on the biological effects and light heat conversion efficiency of gold nanoshells on silica nanorattles.

scientific article published on 15 June 2013

Improvement of Stability and Efficacy of C16Y Therapeutic Peptide via Molecular Self-Assembly into Tumor-Responsive Nanoformulation.

scientific article published on 12 August 2015

Improvement of the in vitro safety profile and cytoprotective efficacy of amifostine against chemotherapy by PEGylation strategy.

scientific article published on March 2016

Inhibitory effects of trolox-encapsulated chitosan nanoparticles on tert-butylhydroperoxide induced RAW264.7 apoptosis ⬇️

scientific article published on August 24, 2012

Integration of photothermal therapy and synergistic chemotherapy by a porphyrin self-assembled micelle confers chemosensitivity in triple-negative breast cancer

scientific article published on 2 December 2015

Intrauterine inflammation increases materno-fetal transfer of gold nanoparticles in a size-dependent manner in murine pregnancy

scientific article published on 13 June 2013

Localized electric field of plasmonic nanoplatform enhanced photodynamic tumor therapy.

scientific article

Lysosomal proteolysis is the primary degradation pathway for cytosolic ferritin and cytosolic ferritin degradation is necessary for iron exit.

scientific article published on October 2010

Metabonomic Investigation of Biological Effects of a New Vessel Target Protein tTF-pHLIP in a Mouse Model

scientific article published on 25 October 2019

Mitochondrial ferritin attenuates β-amyloid-induced neurotoxicity: reduction in oxidative damage through the Erk/P38 mitogen-activated protein kinase pathways

scientific article

Mitochondrial ferritin, a new target for inhibiting neuronal tumor cell proliferation

scientific article

Modularly Designed Peptide Nanoprodrug Augments Antitumor Immunity of PD-L1 Checkpoint Blockade by Targeting Indoleamine 2,3-Dioxygenase

scientific article published on 24 January 2020

Mutation spectrum in Chinese patients affected by congenital sideroblastic anemia and a search for a genotype-phenotype relationship

scientific article published on December 2013

Nano Letters Seed Grants, Take Two

scientific article published on 19 September 2024

Nanoparticle-Induced Exosomes Target Antigen-Presenting Cells to Initiate Th1-Type Immune Activation

scientific article published on 06 June 2012

Nanopore film based enrichment and quantification of low abundance hepcidin from human bodily fluids.

scientific article

Neuroprotective mechanism of mitochondrial ferritin on 6-hydroxydopamine-induced dopaminergic cell damage: implication for neuroprotection in Parkinson's disease.

scientific article

No overt structural or functional changes associated with PEG-coated gold nanoparticles accumulation with acute exposure in the mouse heart

scientific article published on 29 July 2013

Overexpression of human wild-type amyloid-β protein precursor decreases the iron content and increases the oxidative stress of neuroblastoma SH-SY5Y cells

scientific article

Overexpression of mitochondrial ferritin causes cytosolic iron depletion and changes cellular iron homeostasis.

scientific article

Peptide assembly integration of fibroblast-targeting and cell-penetration features for enhanced antitumor drug delivery

scientific article

Peroxidase-like activity of apoferritin paired gold clusters for glucose detection.

scientific article published on 3 September 2014

Photothermal Effect Enhanced Cascade-Targeting Strategy for Improved Pancreatic Cancer Therapy by Gold Nanoshell@Mesoporous Silica Nanorod.

scientific article published on 24 July 2017

Physicochemical properties determine nanomaterial cellular uptake, transport, and fate

scientific article

Plasmon-Enhanced Oxidase-Like Activity and Cellular Effect of Pd-Coated Gold Nanorods

scientific article published on 22 November 2019

Polyethylenimine-Poly(lactic-<i>co</i>-glycolic acid)<sub>2</sub> Nanoparticles Show an Innate Targeting Ability to the Submandibular Salivary Gland via the Muscarinic 3 Receptor

scientific article published on 04 November 2021

Polymeric Nanoparticles Enhance the Ability of Deferoxamine To Deplete Hepatic and Systemic Iron

scientific article published on 09 August 2018

Programming conformational cooperativity to regulate allosteric protein-oligonucleotide signal transduction

scientific article published on 14 August 2023

Protective effects of green tea polyphenols and their major component, (-)-epigallocatechin-3-gallate (EGCG), on 6-hydroxydopamine-induced apoptosis in PC12 cells

scientific article published in January 2002

Publisher Correction: A DNA nanodevice-based vaccine for cancer immunotherapy

scientific article published on 16 September 2020

Reshaping Prostate Tumor Microenvironment To Suppress Metastasis via Cancer-Associated Fibroblast Inactivation with Peptide-Assembly-Based Nanosystem

scientific article published on 30 September 2019

Reversal of pancreatic desmoplasia by re-educating stellate cells with a tumour microenvironment-activated nanosystem

scientific article published in Nature Communications

Robust Anticancer Efficacy of a Biologically Synthesized Tumor Acidity-Responsive and Autophagy-Inducing Functional Beclin 1.

scientific article

Self-assembled peptide nanoparticles as tumor microenvironment activatable probes for tumor targeting and imaging

scientific article published on 10 January 2014

Sequentially Responsive Therapeutic Peptide Assembling Nanoparticles for Dual-Targeted Cancer Immunotherapy.

scientific article published on 23 April 2018

Smart Nanotherapeutic Targeting of Tumor Vasculature

scientific article published on 21 August 2019

Specific hemosiderin deposition in spleen induced by a low dose of cisplatin: altered iron metabolism and its implication as an acute hemosiderin formation model

scientific article

Sulforaphane Mediates Glutathione Depletion via Polymeric Nanoparticles to Restore Cisplatin Chemosensitivity

scientific article published on 04 November 2019

Suppression of Tumor Energy Supply by Liposomal Nanoparticle-Mediated Inhibition of Aerobic Glycolysis

scientific article published on 29 December 2017

Surface Functionalization of Polymeric Nanoparticles with Umbilical Cord-Derived Mesenchymal Stem Cell Membrane for Tumor-Targeted Therapy

scientific article published on 26 June 2018

Synthesis and Imaging of Biocompatible Graphdiyne Quantum Dots

scientific article published on 28 August 2019

Targeted Brain Delivery of Rabies Virus Glycoprotein 29-Modified Deferoxamine-Loaded Nanoparticles Reverses Functional Deficits in Parkinsonian Mice.

scientific article

Targeted Co-delivery of the Iron Chelator Deferoxamine and a HIF1α Inhibitor Impairs Pancreatic Tumor Growth

scientific article published on 28 January 2019

Targeting Delivery of Platelets Inhibitor to Prevent Tumor Metastasis

scientific article published on 29 August 2019

Total Aqueous Synthesis of Au@Cu2- x S Core-Shell Nanoparticles for In Vitro and In Vivo SERS/PA Imaging-Guided Photothermal Cancer Therapy

scientific article published on 07 December 2018

Transformable Peptide Nanocarriers for Expeditious Drug Release and Effective Cancer Therapy via Cancer-Associated Fibroblast Activation.

scientific article published on 17 August 2015

Tumor Fibroblast Specific Activation of a Hybrid Ferritin Nanocage‐Based Optical Probe for Tumor Microenvironment Imaging ⬇️

scientific article published on July 22, 2013

Tumor-Specific Silencing of Tissue Factor Suppresses Metastasis and Prevents Cancer-Associated Hypercoagulability

scientific article published on 10 June 2019

Understanding the particokinetics of engineered nanomaterials for safe and effective therapeutic applications

scientific article published on 06 December 2012

Unraveling Stress-Induced Toxicity Properties of Graphene Oxide and the Underlying Mechanism

article

Using functional nanomaterials to target and regulate the tumor microenvironment: diagnostic and therapeutic applications

scientific article published on 24 May 2013

iRGD-coupled responsive fluorescent nanogel for targeted drug delivery

scientific article published on 12 February 2013

pHLIP-mediated targeting of truncated tissue factor to tumor vessels causes vascular occlusion and impairs tumor growth

scientific article

β-Amyloid peptide increases levels of iron content and oxidative stress in human cell and Caenorhabditis elegans models of Alzheimer disease

scientific article published on 26 October 2010

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