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List of works by Roman Hovorka

A Glycemia Risk Index (GRI) of Hypoglycemia and Hyperglycemia for Continuous Glucose Monitoring Validated by Clinician Ratings

scientific article published in 2022

A comparison of six deconvolution techniques

scientific article published in June 1996

A consultation system for insulin therapy

scientific article published in July 1990

A novel method for measuring intestinal and hepatic triacylglycerol kinetics

scientific article published on 16 April 2013

A probabilistic approach to glucose prediction and insulin dose adjustment: description of metabolic model and pilot evaluation study

scientific article published on 01 January 1994

A qualitative study of clinician attitudes towards closed-loop systems in mainstream diabetes care in England

scientific article published on 14 January 2020

A simulation model of glucose regulation in the critically ill.

scientific article published on 18 July 2008

A simulation study to determine optimal insulin priming during glucose clamp studies

scientific article published on 01 January 1994

A stepwise approach toward closed-loop blood glucose control for intensive care unit patients: results from a feasibility study in type 1 diabetic subjects using vascular microdialysis with infrared spectrometry and a model predictive control algori

scientific article

Absorption patterns of meals containing complex carbohydrates in type 1 diabetes

scientific article published on 23 February 2013

Accuracy of Continuous Glucose Monitoring During Three Closed-Loop Home Studies Under Free-Living Conditions

scientific article

Accuracy of continuous glucose monitoring during exercise in type 1 diabetes pregnancy

scientific article published on 27 February 2013

Accuracy of subcutaneous continuous glucose monitoring in critically ill adults: improved sensor performance with enhanced calibrations

scientific article

Acid-base chemistry of the blood--a general model

scientific article published on 01 October 1996

Adaptability of Closed Loop During Labor, Delivery, and Postpartum: A Secondary Analysis of Data from Two Randomized Crossover Trials in Type 1 Diabetes Pregnancy.

scientific article

Advances in artificial pancreas systems

scientific article published on 01 March 2019

Analysing the hypoglycaemic counter-regulation: a clinically relevant phenomenon?

scientific article published on 01 August 1996

Artificial Pancreas Project at Cambridge 2013

scientific article published on 15 April 2015

Artificial pancreas treatment for outpatients with type 1 diabetes: systematic review and meta-analysis

scientific article published on 18 April 2018

Artificial pancreas: an emerging approach to treat Type 1 diabetes

scientific article published on July 2009

Assessing Performance of Closed-Loop Insulin Delivery Systems by Continuous Glucose Monitoring: Drawbacks and Way Forward ⬇️

scientific article published on October 9, 2012

Assessing the effectiveness of 3 months day and night home closed-loop insulin delivery in adults with suboptimally controlled type 1 diabetes: a randomised crossover study protocol

scientific article

Assessing the effectiveness of a 3-month day-and-night home closed-loop control combined with pump suspend feature compared with sensor-augmented pump therapy in youths and adults with suboptimally controlled type 1 diabetes: a randomised parallel s

scientific article

Associations of glucose control with insulin sensitivity and pancreatic beta-cell responsiveness in newly presenting type 2 diabetes

scientific article

Attainment of Metabolic Goals in the Integrated UK Islet Transplant Program With Locally Isolated and Transported Preparations

scientific article published on 01 October 2013

Automated glucose control in the ICU: effect of nutritional protocol and measurement error

scientific article published in January 2006

Automated overnight closed-loop glucose control in young children with type 1 diabetes

scientific article published on 28 February 2011

Available at a flash: a new way to check glucose

scientific article published on 12 September 2016

Bayesian hierarchical approach to estimate insulin sensitivity by minimal model

scientific article

Behavioral Patterns and Associations with Glucose Control During 12-Week Randomized Free-Living Clinical Trial of Day and Night Hybrid Closed-Loop Insulin Delivery in Adults with Type 1 Diabetes

scientific article published on 2 May 2017

Blood glucose control by a model predictive control algorithm with variable sampling rate versus a routine glucose management protocol in cardiac surgery patients: a randomized controlled trial

scientific article published on 5 June 2007

Bolusing frequency and amount impacts glucose control during hybrid closed-loop

scientific article published on 29 July 2017

Bridging technology and clinical practice: innovating inpatient hyperglycaemia management in non-critical care settings.

scientific article published on 21 December 2017

Bringing closed-loop home: recent advances in closed-loop insulin delivery

scientific article published on April 2014

Broadening the Debate About Post-trial Access to Medical Interventions: A Qualitative Study of Participant Experiences at the End of a Trial Investigating a Medical Device to Support Type 1 Diabetes Self-Management

scientific article published on 15 April 2019

CODE: a deconvolution program implementing a regularization method of deconvolution constrained to non-negative values. Description and pilot evaluation ⬇️

scientific article published on January 1, 1998

Clinical Targets for Continuous Glucose Monitoring Data Interpretation: Recommendations From the International Consensus on Time in Range

scientific article published on 08 June 2019

Clinical review: Consensus recommendations on measurement of blood glucose and reporting glycemic control in critically ill adults

scientific article

Closed-Loop Insulin Delivery during Pregnancy in Women with Type 1 Diabetes ⬇️

scientific article

Closed-Loop Insulin Delivery for Glycemic Control in Noncritical Care

scientific article published on 9 August 2018

Closed-Loop Therapy and Preservation of C-Peptide Secretion in Type 1 Diabetes

scientific article published in 2022

Closed-loop basal insulin delivery over 36 hours in adolescents with type 1 diabetes: randomized clinical trial

scientific article published on 27 November 2012

Closed-loop control in insulin pumps for type-1 diabetes mellitus: safety and efficacy

scientific article published on 22 June 2020

Closed-loop for type 1 diabetes - an introduction and appraisal for the generalist

scientific article

Closed-loop insulin delivery during pregnancy complicated by type 1 diabetes

scientific article

Closed-loop insulin delivery for treatment of type 1 diabetes

scientific article

Closed-loop insulin delivery in end-of-life care: a case report

scientific article published on 03 May 2019

Closed-loop insulin delivery in inpatients with type 2 diabetes: a randomised, parallel-group trial

scientific article

Closed-loop insulin delivery in suboptimally controlled type 1 diabetes: a multicentre, 12-week randomised trial

scientific article published in The Lancet

Closed-loop insulin delivery in type 1 diabetes

scientific article

Closed-loop insulin delivery: from bench to clinical practice ⬇️

scientific article published on February 22, 2011

Closing the Loop in Adults, Children and Adolescents With Suboptimally Controlled Type 1 Diabetes Under Free Living Conditions: A Psychosocial Substudy

scientific article

Closing the loop: the adicol experience

scientific article

Coming of age: the artificial pancreas for type 1 diabetes

scientific article

Comment on Doyle et al. Closed-loop artificial pancreas systems: engineering the algorithms. Diabetes Care 2014;37:1191-1197.

scientific article published in October 2014

Comparison of three protocols for tight glycemic control in cardiac surgery patients

scientific article published on 05 February 2009

Computer models of albumin and haemoglobin glycation

scientific article published in July 1990

Consensus Recommendations for the Use of Automated Insulin Delivery (AID) Technologies in Clinical Practice

scientific article published in 2022

Continuous glucose control in the ICU: report of a 2013 round table meeting

scientific article

Continuous subcutaneous insulin infusion in diabetes: patient populations, safety, efficacy, and pharmacoeconomics.

scientific article published on 13 April 2015

Continuous subcutaneous insulin infusion therapy and multiple daily insulin injections in type 1 diabetes mellitus: a comparative overview and future horizons

scientific article

DIAS--the diabetes advisory system: an outline of the system and the evaluation results obtained so far.

scientific article published in September 1997

DIAS-NIDDM--a model-based decision support system for insulin dose adjustment in insulin-treated subjects with NIDDM.

scientific article

Day and night closed-loop control in adults with type 1 diabetes: a comparison of two closed-loop algorithms driving continuous subcutaneous insulin infusion versus patient self-management

scientific article

Day and night home closed-loop insulin delivery in adults with type 1 diabetes: three-center randomized crossover study

scientific article published in July 2014

Day-and-Night Closed-Loop Insulin Delivery in a Broad Population of Pregnant Women With Type 1 Diabetes: A Randomized Controlled Crossover Trial ⬇️

scientific article published on 13 March 2018

Day-and-Night Hybrid Closed-Loop Insulin Delivery in Adolescents With Type 1 Diabetes: A Free-Living, Randomized Clinical Trial

scientific article published on 06 January 2016

Day-and-night glycaemic control with closed-loop insulin delivery versus conventional insulin pump therapy in free-living adults with well controlled type 1 diabetes: an open-label, randomised, crossover study

scientific article published on 13 January 2017

Dynamic updating in DIAS-NIDDM and DIAS causal probabilistic networks.

scientific article

Effect of delay on measurement of blood glucose levels in young subjects with type 1 diabetes.

scientific article published on 29 July 2009

Effects of intravenous infusion of lipid-free apo A-I in humans

scientific article published on 01 September 1996

Effects of prolonged fasting and sustained lipolysis on insulin secretion and insulin sensitivity in normal subjects

scientific article published on 23 December 2008

Effects of rosiglitazone and pioglitazone on lipoprotein metabolism in patients with Type 2 diabetes and normal lipids.

scientific article published in May 2009

Efficacy and safety of glucose control with Space GlucoseControl in the medical intensive care unit--an open clinical investigation

scientific article published on 13 June 2012

Estimating postprandial glucose fluxes using hierarchical Bayes modelling

scientific article published on 23 February 2012

Evaluating glycemic control algorithms by computer simulations

scientific article published on 13 April 2011

Evaluating the Performance of a Novel Embedded Closed-loop System

scientific article published on 24 March 2014

Evaluating the accuracy and large inaccuracy of two continuous glucose monitoring systems

scientific article published on 20 December 2012

Evaluation of a portable ambulatory prototype for automated overnight closed-loop insulin delivery in young people with type 1 diabetes

scientific article published on 23 July 2012

Evaluation of glucose controllers in virtual environment: methodology and sample application

scientific article published in November 2004

Evaluation of implementation of a fully automated algorithm (enhanced model predictive control) in an interacting infusion pump system for establishment of tight glycemic control in medical intensive care unit patients

scientific article published on November 2008

Evaluation of nonlinear regression approaches to estimation of insulin sensitivity by the minimal model with reference to Bayesian hierarchical analysis

scientific article published on 14 February 2006

Experiences of closed-loop insulin delivery among pregnant women with Type 1 diabetes.

scientific article published on 20 June 2017

Factors Affecting Recruitment of Participants for Studies of Diabetes Technology in Newly Diagnosed Youth with Type 1 Diabetes: A Qualitative Focus Group Study with Parents and Children

scientific article published on 29 June 2016

Factors Associated With Glycemic Control During Free-Living Overnight Closed-Loop Insulin Delivery in Children and Adults With Type 1 Diabetes

scientific article published on 7 October 2015

Faster insulin action is associated with improved glycaemic outcomes during closed-loop insulin delivery and sensor-augmented pump therapy in adults with type 1 diabetes.

scientific article

Feasibility of automated insulin delivery guided by continuous glucose monitoring in extremely preterm infants

Feasibility of closed-loop insulin delivery in type 2 diabetes: a randomized controlled study

scientific article published on 11 September 2013

Feasibility of fully automated closed-loop glucose control using continuous subcutaneous glucose measurements in critical illness: a randomized controlled trial.

scientific article

Finding the right route for insulin delivery - an overview of implantable pump therapy

scientific article published on 02 December 2016

Fitting dynamic models with forcing functions: application to continuous glucose monitoring in insulin therapy

scientific article

Further development of artificial pancreas: blocked by patents?

scientific article

Gender differences in VLDL1 and VLDL2 triglyceride kinetics and fatty acid kinetics in obese postmenopausal women and obese men.

scientific article published on 16 April 2012

Glucose Control in the ICU: A Continuing Story

scientific article published on 10 May 2016

Glucose Management Indicator (GMI): Insights and Validation Using Guardian 3 and Navigator 2 Sensor Data

scientific article published on 06 February 2019

Glucose control in intensive care: usability, efficacy and safety of Space GlucoseControl in two medical European intensive care units

scientific article

Glucose control in non-critically ill inpatients with diabetes: towards closed-loop

scientific article

Glucose control in the intensive care unit by use of continuous glucose monitoring: what level of measurement error is acceptable?

scientific article published on 7 October 2014

Glucose turnover after replacement of usual therapy by insulin in insulin-naive type 2 diabetes subjects

scientific article

Glucose-responsive insulin delivery for type 1 diabetes: The artificial pancreas story

scientific article published on 16 December 2017

Glycemic variability correlates strongly with postprandial beta-cell dysfunction in a segment of type 2 diabetic patients using oral hypoglycemic agents

scientific article published on 24 February 2009

Grading system to assess clinical performance of closed-loop glucose control

scientific article published in February 2005

Health professionals' views about who would benefit from using a closed-loop system: a qualitative study

scientific article published on 27 January 2020

Holistic Impact of Closed-Loop Technology on People With Type 1 Diabetes

scientific article published on 7 April 2015

Home Use of Day-and-Night Hybrid Closed-Loop Insulin Delivery in Suboptimally Controlled Adolescents With Type 1 Diabetes: A 3-Week, Free-Living, Randomized Crossover Trial ⬇️

scientific article published on 9 September 2016

Home Use of Day-and-Night Hybrid Closed-Loop Insulin Delivery in Very Young Children: A Multicenter, 3-Week, Randomized Trial

scientific article published on 28 January 2019

Home Use of an Artificial Beta Cell in Type 1 Diabetes

scientific article

Home use of closed-loop insulin delivery for overnight glucose control in adults with type 1 diabetes: a 4-week, multicentre, randomised crossover study

scientific article

Hospital glucose control: safe and reliable glycemic control using enhanced model predictive control algorithm in medical intensive care unit patients

scientific article published in May 2010

Hypoglycaemia Incidence and Recovery During Home Use of Hybrid Closed-Loop Insulin Delivery in Adults with Type 1 Diabetes.

scientific article published on 25 March 2018

ISEC: a program to calculate insulin secretion

scientific article published in August 1996

Identification of insulin receptor systems: assessing the impact of model selection and measurement error on precision of parameter estimates using Monte Carlo study

scientific article published in August 1991

Impact of liver fat on the differential partitioning of hepatic triacylglycerol into VLDL subclasses on high and low sugar diets.

scientific article published on 18 September 2017

Improving glycemic control in critically ill patients: personalized care to mimic the endocrine pancreas

In silico testing--impact on the progress of the closed loop insulin infusion for critically ill patients project

scientific article published on May 2008

Insulin administration and rate of glucose appearance in people with type 1 diabetes

scientific article published on 23 July 2008

Insulin delivery and nocturnal glucose control in children and adolescents with type 1 diabetes

scientific article

Insulin kinetics in type-I diabetes: continuous and bolus delivery of rapid acting insulin

scientific article published in January 2005

Insulin pump therapy in youth with type 1 diabetes: toward closed-loop systems

scientific article published on 21 April 2014

Intense exercise in type 1 diabetes: exploring the role of continuous glucose monitoring

scientific article published on July 2007

Intensive insulin therapy: enhanced Model Predictive Control algorithm versus standard care

scientific article published on 26 July 2008

Intensive insulin therapy: enhanced Model Predictive Control algorithm versus standard care

International Consensus on Use of Continuous Glucose Monitoring.

scientific article published in December 2017

Interstitial glucose kinetics in subjects with type 1 diabetes under physiologic conditions

scientific article published in November 2004

Is an artificial pancreas (closed-loop system) for Type 1 diabetes effective?

scientific article published on 16 October 2018

Lipohypertrophy and the artificial pancreas: is this an issue?

scientific article published on 16 June 2014

Lixisenatide Reduces Chylomicron Triacylglycerol by Increased Clearance

scientific article published on 01 February 2019

Manual closed-loop insulin delivery in children and adolescents with type 1 diabetes: a phase 2 randomised crossover trial

scientific article

Mass kinetics of apolipoprotein A-I in interstitial fluid after administration of intravenous apolipoprotein A-I/lecithin discs in humans

scientific article published on 09 January 2006

Measurement delay associated with the Guardian RT continuous glucose monitoring system

scientific article

Measuring pre-hepatic insulin secretion using a population model of C-peptide kinetics: accuracy and required sampling schedule

scientific article published in May 1998

Meta-analysis of overnight closed-loop randomized studies in children and adults with type 1 diabetes: the Cambridge cohort

scientific article published on November 2011

Mixed-meal tolerance test to assess residual beta-cell secretion: Beyond the area-under-curve of plasma C-peptide concentration

article by Yue Ruan et al published May 2019 in Pediatric Diabetes

Modeling Day-to-Day Variability of Glucose-Insulin Regulation Over 12-Week Home Use of Closed-Loop Insulin Delivery

scientific article published on 8 September 2016

Modelling endogenous insulin concentration in type 2 diabetes during closed-loop insulin delivery

scientific article

Modelling the effect of insulin on the disposal of meal-attributable glucose in type 1 diabetes

scientific article published on 7 May 2016

Multicentric, randomized, controlled trial to evaluate blood glucose control by the model predictive control algorithm versus routine glucose management protocols in intensive care unit patients

scientific article published in February 2006

Multicentric, randomized, controlled trial to evaluate blood glucose control by the model predictive control algorithm versus routine glucose management protocols in intensive care unit patients: Response to Ligtenberg et al.

scientific article published in August 2006

Nonlinear model predictive control of glucose concentration in subjects with type 1 diabetes.

scientific article

Novel Single-Site Device for Conjoined Glucose Sensing and Insulin Infusion: Performance Evaluation in Diabetes Patients During Home-Use

scientific article published on 27 June 2019

On-line adaptive algorithm with glucose prediction capacity for subcutaneous closed loop control of glucose: evaluation under fasting conditions in patients with Type 1 diabetes.

scientific article published in January 2006

Outcome Measures for Artificial Pancreas Clinical Trials: A Consensus Report

scientific article

Overnight closed loop insulin delivery (artificial pancreas) in adults with type 1 diabetes: crossover randomised controlled studies

scientific article (publication date: 13 April 2011)

Overnight closed-loop insulin delivery in young people with type 1 diabetes: a free-living, randomized clinical trial

scientific article published on January 2014

Overnight closed-loop insulin delivery with model predictive control: assessment of hypoglycemia and hyperglycemia risk using simulation studies

scientific article published on September 2009

Pancreatic -Cell Responsiveness during Meal Tolerance Test: Model Assessment in Normal Subjects and Subjects with Newly Diagnosed Noninsulin-Dependent Diabetes Mellitus

article

Pancreatic β-Cell Responsiveness during Meal Tolerance Test: Model Assessment in Normal Subjects and Subjects with Newly Diagnosed Noninsulin-Dependent Diabetes Mellitus1 ⬇️

scientific article published on March 1, 1998

Parental attitudes towards overnight closed-loop glucose control in children with type 1 diabetes

scientific article published in January 2010

Parenteral glucose and glucose control in the critically ill: a kinetic appraisal

scientific article published on May 2007

Pathophysiology of postprandial hyperglycaemia in women with type 1 diabetes during pregnancy

scientific article published on 12 November 2011

Patients' and caregivers' experiences of using continuous glucose monitoring to support diabetes self-management: qualitative study

scientific article published on 20 February 2018

Perioperative Tight Glucose Control Reduces Postoperative Adverse Events in Nondiabetic Cardiac Surgery Patients

scientific article

Pharmacokinetics of diluted (U20) insulin aspart compared with standard (U100) in children aged 3-6 years with type 1 diabetes during closed-loop insulin delivery: a randomised clinical trial

scientific article

Pharmacokinetics of insulin aspart in pregnant women with type 1 diabetes: every day is different

scientific article published on 01 June 2014

Pharmacokinetics of insulin aspart in pump-treated subjects with type 1 diabetes: reproducibility and effect of age, weight, and duration of diabetes

scientific article published on October 2013

Pharmacokinetics of insulin lispro in type 2 diabetes during closed-loop insulin delivery

scientific article published on 22 July 2014

Physical activity energy expenditure and glucose control in pregnant women with type 1 diabetes: is 30 minutes of daily exercise enough?

scientific article published on 12 February 2013

Plasma C-peptide concentration in women with Type 1 diabetes during early and late pregnancy

scientific article published in October 2012

Population and individual minimal modeling of the frequently sampled insulin-modified intravenous glucose tolerance test

scientific article published in October 2004

Prandial hypertriglyceridemia in metabolic syndrome is due to an overproduction of both chylomicron and VLDL triacylglycerol

scientific article published on 29 August 2013

Preliminary experience of the DIAS computer model in providing insulin dose advice to patients with insulin dependent diabetes

article

Psychosocial aspects of closed- and open-loop insulin delivery: closing the loop in adults with Type 1 diabetes in the home setting

scientific article published on 20 February 2015

Quantifying the acute changes in glucose with exercise in type 1 diabetes: a systematic review and meta-analysis

scientific article

Quantitative measurement of 3-O-methyl-D-glucose by gas chromatography-mass spectrometry as a measure of glucose transport in vivo

scientific article published on 01 September 1996

Rapid Benefits of Structured Optimization and Sensor-Augmented Insulin Pump Therapy in Adults With Type 1 Diabetes

scientific article published on 21 June 2016

Rapid model exploration for complex hierarchical data: application to pharmacokinetics of insulin aspart

scientific article published on 26 May 2015

Reduced burden of diabetes and improved quality of life: Experiences from unrestricted day-and-night hybrid closed-loop use in very young children with type 1 diabetes

scientific article published on 13 June 2019

Relation between insulin kinetics and insulin sensitivity in pregnancy

scientific article

Relationship between beta-cell responsiveness and fasting plasma glucose in Caucasian subjects with newly presenting type 2 diabetes

scientific article published in October 2001

Reproducibility and comparability of insulin sensitivity indices measured by stable-label intravenous glucose tolerance test

scientific article published on 01 March 1998

Response to Mitre et al.: "analysis of continuous glucose monitoring data to assess outpatient closed-loop studies: considerations for different sensors".

scientific article published on April 2014

Risk calculation of type 2 diabetes

scientific article published on 01 January 1994

Role of Dual-Hormone Closed-Loop Delivery System in the Future

scientific article published on 8 August 2016

Safety and efficacy of 24-h closed-loop insulin delivery in well-controlled pregnant women with type 1 diabetes: a randomized crossover case series

scientific article published on 19 October 2011

Safety of closed-loop therapy during reduction or omission of meal boluses in adolescents with type 1 diabetes: a randomized clinical trial

scientific article

Safety, efficacy and glucose turnover of reduced prandial boluses during closed-loop therapy in adolescents with type 1 diabetes: a randomized clinical trial

scientific article published on 8 August 2015

Sensor Life and Overnight Closed Loop: A Randomized Clinical Trial.

scientific article published on 10 November 2016

Sensor mightier than pump-the jury is still out

scientific article published on 12 July 2017

Simulation environment to evaluate closed-loop insulin delivery systems in type 1 diabetes

scientific article

Stochastic Virtual Population of Subjects With Type 1 Diabetes for the Assessment of Closed-Loop Glucose Controllers

scientific article published on 11 July 2013

Suspended insulin infusion during overnight closed-loop glucose control in children and adolescents with Type 1 diabetes.

scientific article published in April 2010

Technology in the management of type 1 diabetes mellitus - current status and future prospects

The Future of the Artificial Pancreas

scientific article

The future of continuous glucose monitoring: closed loop

scientific article published on August 2008

The impact of using a closed-loop system on food choices and eating practices among people with Type 1 diabetes: a qualitative study involving adults, teenagers and parents

scientific article published on 29 January 2019

The importance of prandial insulin bolus timing with hybrid closed-loop systems

scientific article published on 09 September 2019

The use of continuous glucose monitoring combined with computer-based eMPC algorithm for tight glucose control in cardiosurgical ICU.

scientific article

Tight glycaemic control by an automated algorithm with time-variant sampling in medical ICU patients

scientific article

Treatment with recombinant human insulin-like growth factor (rhIGF)-I/rhIGF binding protein-3 complex improves metabolic control in subjects with severe insulin resistance

scientific article published on 16 March 2010

Unsupervised home use of an overnight closed-loop system over 3-4 weeks: a pooled analysis of randomized controlled studies in adults and adolescents with type 1 diabetes.

scientific article published on 9 January 2015

Use of the DIAS model to predict unrecognised hypoglycaemia in patients with insulin-dependent diabetes

article

Using a double blind controlled clinical trial to evaluate the function of a Diabetes Advisory System: a feasible approach?

scientific article published on 01 May 1998

Validity of triple- and dual-tracer techniques to estimate glucose appearance.

scientific article

Variability of Insulin Requirements Over 12 Weeks of Closed-Loop Insulin Delivery in Adults With Type 1 Diabetes

scientific article published on 10 March 2016

Women's Experiences of Day-and-Night Closed-Loop Insulin Delivery During Type 1 Diabetes Pregnancy

scientific article published on 05 October 2018

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