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List of works by Malin Parmar

3D-Printed Soft Lithography for Complex Compartmentalized Microfluidic Neural Devices

scientific article published on 15 June 2020

A systematic capsid evolution approach performed in vivo for the design of AAV vectors with tailored properties and tropism

scientific article published on 09 December 2019

A transplantation study of expanded human embryonic forebrain precursors: evidence for selection of a specific progenitor population

scientific article

Activity in grafted human iPS cell-derived cortical neurons integrated in stroke-injured rat brain regulates motor behavior

scientific article published on 06 April 2020

Advances in stem cell research and therapeutic development

scientific article published on 17 June 2019

Are Stem Cell-Based Therapies for Parkinson's Disease Ready for the Clinic in 2016?

scientific article

Author Correction: Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson's disease

scientific article published on 15 July 2020

Author Correction: Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organoids

correction of a scholarly article

Brain repair and reprogramming: the route to clinical translation.

scientific article published on September 2016

Building authentic midbrain dopaminergic neurons from stem cells - lessons from development

scientific article published in January 2012

Cell-based therapies for Parkinson disease—past insights and future potential

scientific article published on 4 August 2015

Cell-based therapy for Parkinson's disease: A journey through decades toward the light side of the Force

scientific article published on 09 September 2018

Comparability: manufacturing, characterization and controls, report of a UK Regenerative Medicine Platform Pluripotent Stem Cell Platform Workshop, Trinity Hall, Cambridge, 14-15 September 2015.

scientific article

Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor.

scientific article

Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming.

scientific article published on 13 November 2017

DREADD Modulation of Transplanted DA Neurons Reveals a Novel Parkinsonian Dyskinesia Mechanism Mediated by the Serotonin 5-HT6 Receptor

scientific article published on 04 May 2016

Developing defined substrates for stem cell culture and differentiation.

scientific article published in July 2018

Development of the mesencephalic dopaminergic neuron system is compromised in the absence of neurogenin 2

scientific journal article

Direct Neuronal Reprogramming for Disease Modeling Studies Using Patient-Derived Neurons: What Have We Learned?

scientific article published on 28 September 2017

Direct Reprogramming of Resident NG2 Glia into Neurons with Properties of Fast-Spiking Parvalbumin-Containing Interneurons.

scientific article

Direct conversion of human fibroblasts to dopaminergic neurons ⬇️

scientific article

Direct neural conversion from human fibroblasts using self-regulating and nonintegrating viral vectors.

scientific article

Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus

scientific article published on 26 November 2017

Dopamine neuron precursors within the developing human mesencephalon show radial glial characteristics.

scientific article

Dual modulation of neuron-specific microRNAs and the REST complex promotes functional maturation of human adult induced neurons

scientific article published on 10 October 2019

Early specification of dopaminergic phenotype during ES cell differentiation

scientific article

Efficient expansion and dopaminergic differentiation of human fetal ventral midbrain neural stem cells by midbrain morphogens

scientific article

Efficient induction of functional neurons from adult human fibroblasts

scientific article published in October 2011

Expression of Meis and Pbx genes and their protein products in the developing telencephalon: implications for regional differentiation

scientific journal article

FoxP1 promotes midbrain identity in embryonic stem cell-derived dopamine neurons by regulating Pitx3.

scientific article

From Skin to Brain: A Parkinson's Disease Patient Transplanted with His Own Cells

scientific article published on 01 July 2020

GFORCE-PD still going strong in 2016.

scientific article published on 23 February 2017

Generating regionalized neuronal cells from pluripotency, a step-by-step protocol

scientific article published on January 2012

Generation of Transplantable Striatal Projection Neurons from Human ESCs ⬇️

scientific article published on 01 April 2012

Generation of high-purity human ventral midbrain dopaminergic progenitors for in vitro maturation and intracerebral transplantation

scientific article published on 31 August 2017

Generation of human cortical neurons from a new immortal fetal neural stem cell line.

scientific article

Generation of induced neurons via direct conversion in vivo

scientific article

Generation of regionally specified neural progenitors and functional neurons from human embryonic stem cells under defined conditions

scientific article published on 26 May 2012

Highly efficient generation of induced neurons from human fibroblasts that survive transplantation into the adult rat brain.

scientific article

Human ESC-derived dopamine neurons show similar preclinical efficacy and potency to fetal neurons when grafted in a rat model of Parkinson's disease

scientific article

Human Trials of Stem Cell-Derived Dopamine Neurons for Parkinson's Disease: Dawn of a New Era.

scientific article published in November 2017

Human foetal brain tissue as quality control when developing stem cells towards cell replacement therapy for neurological diseases.

scientific article published on December 2013

Human iPS cell-derived dopaminergic neurons function in a primate Parkinson's disease model.

scientific article published in August 2017

Huntingtin Aggregation Impairs Autophagy, Leading to Argonaute-2 Accumulation and Global MicroRNA Dysregulation

scientific article published on 01 August 2018

IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells.

scientific article published on 19 September 2017

Identification of embryonic stem cell-derived midbrain dopaminergic neurons for engraftment

scientific article

Impact of α-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized α-synuclein rat model of PD

scientific article published on 15 June 2020

In Vivo Reprogramming for Brain and Spinal Cord Repair

scientific article

In Vivo Reprogramming of Striatal NG2 Glia into Functional Neurons that Integrate into Local Host Circuitry

scientific article published on 9 July 2015

In vitro characterization of a human neural progenitor cell coexpressing SSEA4 and CD133.

scientific article

Isolation and characterization of neural precursor cells from the Sox1-GFP reporter mouse.

scientific article published in October 2005

Isolation of human induced pluripotent stem cell-derived dopaminergic progenitors by cell sorting for successful transplantation

scientific article published on 06 March 2014

Lineage reprogramming: a shortcut to generating functional neurons from fibroblasts.

scientific article published in October 2011

Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient

scientific article published on 25 May 2020

Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons

scientific article published on 21 May 2015

Neural grafting in Parkinson's disease Problems and possibilities

scientific article published on January 2010

Neurogenin2 identifies a transplantable dopamine neuron precursor in the developing ventral mesencephalon

scientific article published on 24 January 2006

New approaches for brain repair—from rescue to reprogramming

scientific article published in Nature

Ngn2 and Nurr1 act in synergy to induce midbrain dopaminergic neurons from expanded neural stem and progenitor cells

scientific article

Organization of the human embryonic ventral mesencephalon.

scientific article published on 13 October 2009

Phenotypic and molecular identity of cells in the adult subventricular zone. in vivo and after expansion in vitro

scientific article

Plug and Play Brain: Understanding Integration of Transplanted Neurons for Brain Repair

scientific article

Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson's Disease

scientific article

Profiling of lincRNAs in human pluripotent stem cell derived forebrain neural progenitor cells

scientific article published on 31 December 2019

Publisher Correction: Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient

scientific article published on 11 June 2020

REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways

scientific article

Regional specification of neurosphere cultures derived from subregions of the embryonic telencephalon

scientific article

Repairing the Brain: Cell Replacement Using Stem Cell-Based Technologies ⬇️

scientific article published on 01 January 2018

Reprogramming of neonatal SVZ progenitors by islet-1 and neurogenin-2.

scientific article

Retrovirally delivered Islet-1 increases recruitment of Ng2 expressing cells from the postnatal SVZ into the striatum

scientific article published on 27 June 2006

Robust derivation of transplantable dopamine neurons from human pluripotent stem cells by timed retinoic acid delivery

scientific article published on 01 June 2022

Simple Generation of a High Yield Culture of Induced Neurons from Human Adult Skin Fibroblasts.

scientific article published on 5 February 2018

Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson's disease

scientific article published on 15 May 2020

Single-Cell Analysis Reveals a Close Relationship between Differentiating Dopamine and Subthalamic Nucleus Neuronal Lineages.

scientific article published on 27 October 2016

Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development

scientific article published in Nature Communications

Small molecules increase direct neural conversion of human fibroblasts

scientific article

Stem cell culture conditions and stability: a joint workshop of the PluriMes Consortium and Pluripotent Stem Cell Platform

scientific article published on 01 March 2019

Strategies for bringing stem cell-derived dopamine neurons to the clinic: A European approach (STEM-PD).

scientific article published on 07 February 2017

Strengths and limitations of the neurosphere culture system

scientific article published in December 2006

Striatal neuron differentiation from neurosphere-expanded progenitors depends on Gsh2 expression.

scientific article published in August 2004

Synaptic inputs from stroke-injured brain to grafted human stem cell-derived neurons activated by sensory stimuli.

scientific article

TRIM28 Controls a Gene Regulatory Network Based on Endogenous Retroviruses in Human Neural Progenitor Cells

scientific article

Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats

scientific article published on 31 July 2018

Term amniotic fluid: an unexploited reserve of mesenchymal stromal cells for reprogramming and potential cell therapy applications.

scientific article published on 25 August 2017

The differentiation potential of precursor cells from the mouse lateral ganglionic eminence is restricted by in vitro expansion.

scientific article

The future of stem cell therapies for Parkinson disease

scientific article published on 06 January 2020

The novel MAPT mutation K298E: mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neurons

scientific article

Towards stem cell based therapies for Parkinson's disease

scientific article published on 8 January 2018

Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors

scientific article

Transsynaptic tracing and its emerging use to assess graft-reconstructed neural circuits

scientific article published on 26 February 2020

Turning skin into dopamine neurons

scientific article published on 09 August 2011

hESC-Derived Dopaminergic Transplants Integrate into Basal Ganglia Circuitry in a Preclinical Model of Parkinson's Disease

scientific article published on 01 September 2019

hESC-derived neural progenitors prevent xenograft rejection through neonatal desensitisation.

scientific article published on 25 May 2016

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