List of works - Joyce Bischoff

0260 : Endoglin in adhesion between endothelial and mural cells

0304 : Treprostinil indirectly regulates endothelial colony forming cell angiogenic properties by increasing VEGF-A produced by mesenchymal stem cells

3D Ultrasound: seeing is understanding-from imaging to pathophysiology to developing therapies in secondary MR.

scientific article published on 13 March 2016

A role for sialyl Lewis-X/A glycoconjugates in capillary morphogenesis ⬇️

scientific article published on September 16, 1993

A simplified method for growth of human microvascular endothelial cells results in decreased senescence and continued responsiveness to cytokines and growth factors.

scientific article published on April 1998

A somatic GNA11 mutation is associated with extremity capillary malformation and overgrowth.

scientific article

A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma.

scientific article

AKT hyper-phosphorylation associated with PI3K mutations in lymphatic endothelial cells from a patient with lymphatic malformation.

scientific article

Active adaptation of the tethered mitral valve: insights into a compensatory mechanism for functional mitral regurgitation.

scientific article published on 13 July 2009

Altered ratios of pro- and anti-angiogenic VEGF-A variants and pericyte expression of DLL4 disrupt vascular maturation in infantile haemangioma

scientific article published on 9 March 2016

Angiostatin upregulates E-selectin in proliferating endothelial cells

scientific article published on 01 April 1998

Aortic valve endothelial cells undergo transforming growth factor-beta-mediated and non-transforming growth factor-beta-mediated transdifferentiation in vitro

scientific article published on October 2001

Approaches to studying cell adhesion molecules in angiogenesis

scientific article published on 01 February 1995

Bioengineered human vascular networks transplanted into secondary mice reconnect with the host vasculature and re-establish perfusion.

scientific article published on 28 October 2011

CD45 Expression in Mitral Valve Endothelial Cells After Myocardial Infarction.

scientific article published on 6 October 2016

Calcification of multipotent prostate tumor endothelium

scientific article published in September 2008

Chapter 13. An in vivo experimental model for postnatal vasculogenesis

scientific article

Clonality and altered behavior of endothelial cells from hemangiomas.

scientific article

Cooperation between human fibrocytes and endothelial colony-forming cells increases angiogenesis via the CXCR4 pathway.

scientific article published on 7 August 2014

Cyclic strain induces dual-mode endothelial-mesenchymal transformation of the cardiac valve.

scientific article published on 28 November 2011

Differential expression of CD146 in tissues and endothelial cells derived from infantile haemangioma and normal human skin

scientific article published in October 2003

Differential functions of genes regulated by VEGF-NFATc1 signaling pathway in the migration of pulmonary valve endothelial cells

scientific article

Dual role of fatty acid-binding protein 5 on endothelial cell fate: a potential link between lipid metabolism and angiogenic responses

scientific article published in December 2015

E-selectin is required for the antiangiogenic activity of endostatin

scientific article

E-selectin is upregulated in proliferating endothelial cells in vitro

scientific article published on 01 June 1997

E-selectin mediates stem cell adhesion and formation of blood vessels in a murine model of infantile hemangioma

scientific article

EGFL6 Regulates the Asymmetric Division, Maintenance, and Metastasis of ALDH+ Ovarian Cancer Cells

scientific article published on November 2016

Effect of Losartan on Mitral Valve Changes After Myocardial Infarction

scientific article published in September 2017

Endoglin regulates mural cell adhesion in the circulatory system

scientific article

Endothelial Cells from Capillary Malformations Are Enriched for Somatic GNAQ Mutations

scientific article published on 10 September 2015

Endothelial PGC-1α mediates vascular dysfunction in diabetes.

scientific article

Endothelial colony forming cells and mesenchymal progenitor cells form blood vessels and increase blood flow in ischemic muscle.

scientific article

Endothelial progenitor cells as a sole source for ex vivo seeding of tissue-engineered heart valves.

scientific article

Endothelial progenitor cells from infantile hemangioma and umbilical cord blood display unique cellular responses to endostatin.

scientific article published in August 2006

Endothelial progenitor cells in infantile hemangioma

scientific article published on 23 October 2003

Engineering of blood vessels from acellular collagen matrices coated with human endothelial cells

scientific article published on August 2006

Engineering robust and functional vascular networks in vivo with human adult and cord blood-derived progenitor cells.

scientific article published on 12 June 2008

Epsin-mediated degradation of IP3R1 fuels atherosclerosis

scientific article published on 07 August 2020

Expression of HES and HEY genes in infantile hemangiomas ⬇️

scientific article published on August 11, 2011

Fatty acid binding protein 4 is a target of VEGF and a regulator of cell proliferation in endothelial cells.

scientific article published on 22 July 2009

Functional small-diameter neovessels created using endothelial progenitor cells expanded ex vivo

scientific article

Genomic imprinting of IGF2 is maintained in infantile hemangioma despite its high level of expression.

scientific article published in July 2004

Glucose transporter 1-positive endothelial cells in infantile hemangioma exhibit features of facultative stem cells.

scientific article

Heart valve development: endothelial cell signaling and differentiation

scientific article

Hemogenic endothelial progenitor cells isolated from human umbilical cord blood

scientific article

Host myeloid cells are necessary for creating bioengineered human vascular networks in vivo.

scientific article

Human pulmonary valve progenitor cells exhibit endothelial/mesenchymal plasticity in response to vascular endothelial growth factor-A and transforming growth factor-beta2.

scientific article

Human vasculogenic cells form functional blood vessels and mitigate adverse remodeling after ischemia reperfusion injury in rats ⬇️

scientific article published on May 12, 2013

Hydrogel surfaces to promote attachment and spreading of endothelial progenitor cells.

scientific article published on 6 January 2012

Hypoxia enhances stimulus-dependent induction of E-selectin on aortic endothelial cells.

scientific article published on July 1996

In memoriam Dr. Judah Folkman

scientific article published in January 2008

In vivo vasculogenic potential of human blood-derived endothelial progenitor cells

scientific article published on 27 February 2007

Increased Tie2 expression, enhanced response to angiopoietin-1, and dysregulated angiopoietin-2 expression in hemangioma-derived endothelial cells.

scientific article published on December 2001

Infantile hemangioma-derived stem cells and endothelial cells are inhibited by class 3 semaphorins

scientific article published on 15 June 2015

Infantile hemangioma-mechanism(s) of drug action on a vascular tumor.

scientific article published on September 2011

Infantile hemangiomas: current knowledge, future directions. Proceedings of a research workshop on infantile hemangiomas, April 7-9, 2005, Bethesda, Maryland, USA.

scientific article published in September 2005

Intravital molecular imaging of small-diameter tissue-engineered vascular grafts in mice: a feasibility study

scientific article published in August 2010

JAGGED1 Signaling Regulates Hemangioma Stem Cell–to–Pericyte/Vascular Smooth Muscle Cell Differentiation ⬇️

scientific article published on July 14, 2011

Losartan inhibits endothelial-to-mesenchymal transformation in mitral valve endothelial cells by blocking transforming growth factor-β-induced phosphorylation of ERK.

scientific article

Mesenchymal stem cells and adipogenesis in hemangioma involution

scientific article

Mitral Leaflet Changes Following Myocardial Infarction: Clinical Evidence for Maladaptive Valvular Remodeling

scientific article published in November 2017

Mitral valve disease--morphology and mechanisms

scientific article

Mitral valve endothelial cells with osteogenic differentiation potential.

scientific article

Monoclonal expansion of endothelial cells in hemangioma: an intrinsic defect with extrinsic consequences?

scientific article published in July 2002

Myocardial Infarction Alters Adaptation of the Tethered Mitral Valve.

scientific article published on January 2016

Neuropilin-1 functions as a VEGFR2 co-receptor to guide developmental angiogenesis independent of ligand binding

scientific article

Opposing actions of Notch1 and VEGF in post-natal cardiac valve endothelial cells

scientific article published on 21 July 2008

Pathogenesis of infantile haemangioma.

scientific article published on July 2013

Pericytes from infantile hemangioma display proangiogenic properties and dysregulated angiopoietin-1

scientific article published on 3 January 2013

Progenitor cells confer plasticity to cardiac valve endothelium.

scientific article published on 26 July 2011

Progenitor cells in infantile hemangioma.

scientific article published on March 2009

Propranolol targets the contractility of infantile haemangioma-derived pericytes.

scientific article

Quantitative evaluation of endothelial progenitors and cardiac valve endothelial cells: proliferation and differentiation on poly-glycolic acid/poly-4-hydroxybutyrate scaffold in response to vascular endothelial growth factor and transforming growth

scientific article published in June 2003

R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangioma

scientific article published on 30 July 2019

Rapamycin Suppresses Self-Renewal and Vasculogenic Potential of Stem Cells Isolated from Infantile Hemangioma ⬇️

scientific article published on September 22, 2011

Rapamycin improves TIE2-mutated venous malformation in murine model and human subjects

scientific article

Rapid onset of perfused blood vessels after implantation of ECFCs and MPCs in collagen, PuraMatrix and fibrin provisional matrices

scientific article published on 16 August 2013

Reciprocal interactions between mitral valve endothelial and interstitial cells reduce endothelial-to-mesenchymal transition and myofibroblastic activation.

scientific article

Regulation of vascular endothelial growth factor-dependent retinal neovascularization by insulin-like growth factor-1 receptor

scientific article published on 01 December 1999

Somatic Activating Mutations in GNAQ and GNA11 Are Associated with Congenital Hemangioma

scientific article published on April 2016

Somatic Activating Mutations in GNAQ and GNA11 Are Associated with Congenital Hemangioma.

scientific article

Somatic GNAQ Mutation is Enriched in Brain Endothelial Cells in Sturge-Weber Syndrome

scientific article

Stem cell-derived, tissue-engineered pulmonary artery augmentation patches in vivo

scientific article

Suppressed NFAT-dependent VEGFR1 expression and constitutive VEGFR2 signaling in infantile hemangioma

scientific article published on 19 October 2008

Targeting NF-κB in infantile hemangioma-derived stem cells reduces VEGF-A expression.

scientific article

The GPR 55 agonist, L-α-lysophosphatidylinositol, mediates ovarian carcinoma cell-induced angiogenesis

scientific article

The angiogenesis inhibitor AGM-1470 selectively increases E-selectin

scientific article published on 01 August 1996

The effect of 1-deoxymannojirimycin on rat liver alpha-mannosidases

scientific article published on 01 November 1984

The endogenous zinc finger transcription factor, ZNF24, modulates the angiogenic potential of human microvascular endothelial cells

scientific article published on 30 December 2014

Thoracic Surgery Directors Association Award. Bone marrow as a cell source for tissue engineering heart valves

scientific article published in March 2003

Treprostinil indirectly regulates endothelial colony forming cell angiogenic properties by increasing VEGF-A produced by mesenchymal stem cells

article

Treprostinil indirectly regulates endothelial colony forming cell angiogenic properties by increasing VEGF-A produced by mesenchymal stem cells

scientific article published on 11 June 2015

Type I collagen, fibrin and PuraMatrix matrices provide permissive environments for human endothelial and mesenchymal progenitor cells to form neovascular networks

scientific article

VEGFR-1 mediates endothelial differentiation and formation of blood vessels in a murine model of infantile hemangioma.

scientific article

Valvular interstitial cells suppress calcification of valvular endothelial cells

scientific article

Vascular endothelial growth factor receptor signaling is required for cardiac valve formation in zebrafish.

scientific article

Vasculogenesis in infantile hemangioma.

scientific article

Wnt Site Signaling Inhibitor Secreted Frizzled-Related Protein 3 Protects Mitral Valve Endothelium From Myocardial Infarction-Induced Endothelial-to-Mesenchymal Transition

scientific article published on 29 March 2022

miR-21 represses Pdcd4 during cardiac valvulogenesis.

scientific article published on 11 April 2013

α6-Integrin is required for the adhesion and vasculogenic potential of hemangioma stem cells

scientific article published on March 2014

List of works by Joyce Bischoff

0260 : Endoglin in adhesion between endothelial and mural cells

0304 : Treprostinil indirectly regulates endothelial colony forming cell angiogenic properties by increasing VEGF-A produced by mesenchymal stem cells

3D Ultrasound: seeing is understanding-from imaging to pathophysiology to developing therapies in secondary MR.

A role for sialyl Lewis-X/A glycoconjugates in capillary morphogenesis ⬇️

A simplified method for growth of human microvascular endothelial cells results in decreased senescence and continued responsiveness to cytokines and growth factors.

A somatic GNA11 mutation is associated with extremity capillary malformation and overgrowth.

A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma.

AKT hyper-phosphorylation associated with PI3K mutations in lymphatic endothelial cells from a patient with lymphatic malformation.

Active adaptation of the tethered mitral valve: insights into a compensatory mechanism for functional mitral regurgitation.

Altered ratios of pro- and anti-angiogenic VEGF-A variants and pericyte expression of DLL4 disrupt vascular maturation in infantile haemangioma

Angiostatin upregulates E-selectin in proliferating endothelial cells

Aortic valve endothelial cells undergo transforming growth factor-beta-mediated and non-transforming growth factor-beta-mediated transdifferentiation in vitro

Approaches to studying cell adhesion molecules in angiogenesis

Bioengineered human vascular networks transplanted into secondary mice reconnect with the host vasculature and re-establish perfusion.

CD45 Expression in Mitral Valve Endothelial Cells After Myocardial Infarction.

Calcification of multipotent prostate tumor endothelium

Chapter 13. An in vivo experimental model for postnatal vasculogenesis

Clonality and altered behavior of endothelial cells from hemangiomas.

Cooperation between human fibrocytes and endothelial colony-forming cells increases angiogenesis via the CXCR4 pathway.

Cyclic strain induces dual-mode endothelial-mesenchymal transformation of the cardiac valve.

Differential expression of CD146 in tissues and endothelial cells derived from infantile haemangioma and normal human skin

Differential functions of genes regulated by VEGF-NFATc1 signaling pathway in the migration of pulmonary valve endothelial cells

Dual role of fatty acid-binding protein 5 on endothelial cell fate: a potential link between lipid metabolism and angiogenic responses

E-selectin is required for the antiangiogenic activity of endostatin

E-selectin is upregulated in proliferating endothelial cells in vitro

E-selectin mediates stem cell adhesion and formation of blood vessels in a murine model of infantile hemangioma

EGFL6 Regulates the Asymmetric Division, Maintenance, and Metastasis of ALDH+ Ovarian Cancer Cells

Effect of Losartan on Mitral Valve Changes After Myocardial Infarction

Endoglin regulates mural cell adhesion in the circulatory system

Endothelial Cells from Capillary Malformations Are Enriched for Somatic GNAQ Mutations

Endothelial PGC-1α mediates vascular dysfunction in diabetes.

Endothelial colony forming cells and mesenchymal progenitor cells form blood vessels and increase blood flow in ischemic muscle.

Endothelial progenitor cells as a sole source for ex vivo seeding of tissue-engineered heart valves.

Endothelial progenitor cells from infantile hemangioma and umbilical cord blood display unique cellular responses to endostatin.

Endothelial progenitor cells in infantile hemangioma

Engineering of blood vessels from acellular collagen matrices coated with human endothelial cells

Engineering robust and functional vascular networks in vivo with human adult and cord blood-derived progenitor cells.

Epsin-mediated degradation of IP3R1 fuels atherosclerosis

Expression of HES and HEY genes in infantile hemangiomas ⬇️

Fatty acid binding protein 4 is a target of VEGF and a regulator of cell proliferation in endothelial cells.

Functional small-diameter neovessels created using endothelial progenitor cells expanded ex vivo

Genomic imprinting of IGF2 is maintained in infantile hemangioma despite its high level of expression.

Glucose transporter 1-positive endothelial cells in infantile hemangioma exhibit features of facultative stem cells.

Heart valve development: endothelial cell signaling and differentiation

Hemogenic endothelial progenitor cells isolated from human umbilical cord blood

Host myeloid cells are necessary for creating bioengineered human vascular networks in vivo.

Human pulmonary valve progenitor cells exhibit endothelial/mesenchymal plasticity in response to vascular endothelial growth factor-A and transforming growth factor-beta2.

Human vasculogenic cells form functional blood vessels and mitigate adverse remodeling after ischemia reperfusion injury in rats ⬇️

Hydrogel surfaces to promote attachment and spreading of endothelial progenitor cells.

Hypoxia enhances stimulus-dependent induction of E-selectin on aortic endothelial cells.

In memoriam Dr. Judah Folkman

In vivo vasculogenic potential of human blood-derived endothelial progenitor cells

Increased Tie2 expression, enhanced response to angiopoietin-1, and dysregulated angiopoietin-2 expression in hemangioma-derived endothelial cells.

Infantile hemangioma-derived stem cells and endothelial cells are inhibited by class 3 semaphorins

Infantile hemangioma-mechanism(s) of drug action on a vascular tumor.

Infantile hemangiomas: current knowledge, future directions. Proceedings of a research workshop on infantile hemangiomas, April 7-9, 2005, Bethesda, Maryland, USA.

Intravital molecular imaging of small-diameter tissue-engineered vascular grafts in mice: a feasibility study

JAGGED1 Signaling Regulates Hemangioma Stem Cell–to–Pericyte/Vascular Smooth Muscle Cell Differentiation ⬇️

Losartan inhibits endothelial-to-mesenchymal transformation in mitral valve endothelial cells by blocking transforming growth factor-β-induced phosphorylation of ERK.

Mesenchymal stem cells and adipogenesis in hemangioma involution

Mitral Leaflet Changes Following Myocardial Infarction: Clinical Evidence for Maladaptive Valvular Remodeling

Mitral valve disease--morphology and mechanisms

Mitral valve endothelial cells with osteogenic differentiation potential.

Monoclonal expansion of endothelial cells in hemangioma: an intrinsic defect with extrinsic consequences?

Myocardial Infarction Alters Adaptation of the Tethered Mitral Valve.

Neuropilin-1 functions as a VEGFR2 co-receptor to guide developmental angiogenesis independent of ligand binding

Opposing actions of Notch1 and VEGF in post-natal cardiac valve endothelial cells

Pathogenesis of infantile haemangioma.

Pericytes from infantile hemangioma display proangiogenic properties and dysregulated angiopoietin-1

Progenitor cells confer plasticity to cardiac valve endothelium.

Progenitor cells in infantile hemangioma.

Propranolol targets the contractility of infantile haemangioma-derived pericytes.

Quantitative evaluation of endothelial progenitors and cardiac valve endothelial cells: proliferation and differentiation on poly-glycolic acid/poly-4-hydroxybutyrate scaffold in response to vascular endothelial growth factor and transforming growth

R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangioma

Rapamycin Suppresses Self-Renewal and Vasculogenic Potential of Stem Cells Isolated from Infantile Hemangioma ⬇️

Rapamycin improves TIE2-mutated venous malformation in murine model and human subjects

Rapid onset of perfused blood vessels after implantation of ECFCs and MPCs in collagen, PuraMatrix and fibrin provisional matrices

Reciprocal interactions between mitral valve endothelial and interstitial cells reduce endothelial-to-mesenchymal transition and myofibroblastic activation.

Regulation of vascular endothelial growth factor-dependent retinal neovascularization by insulin-like growth factor-1 receptor