List of works - Alexander Drzezga

A European multicentre PET study of fibrillar amyloid in Alzheimer's disease

scientific article

A Novel (18)F-Labeled Imidazo[2,1-b]benzothiazole (IBT) for High-Contrast PET Imaging of β-Amyloid Plaques

scientific article published on 19 July 2011

A new integrative model of cerebral activation, deactivation and default mode function in Alzheimer's disease

scientific article

A perspective on the future role of brain pet imaging in exercise science

scientific article published on 15 October 2015

A systematic review on the applications of resting-state fMRI in Parkinson's disease: Does dopamine replacement therapy play a role?

scientific article

AMYPAD Diagnostic and Patient Management Study: Rationale and design

scientific article published on 16 October 2018

Aberrant intrinsic connectivity of hippocampus and amygdala overlap in the fronto-insular and dorsomedial-prefrontal cortex in major depressive disorder

scientific article published on October 2013

Ablative Radioiodtherapie bei niedrigem und intermediärem Rezidivrisiko. Höhere Überlebensrate beim Schilddrüsenkarzinom

scientific article published on June 2016

Amyloid-PET and 18F-FDG-PET in the diagnostic investigation of Alzheimer's disease and other dementias

scientific article published on 01 November 2020

Amyloid-plaque imaging in early and differential diagnosis of dementia

scientific article

Assessment of 18F-PI-2620 as a Biomarker in Progressive Supranuclear Palsy

scientific article published on 01 November 2020

Assessment of the In Vivo Relationship Between Cerebral Hypometabolism, Tau Deposition, TSPO Expression, and Synaptic Density in a Tauopathy Mouse Model: a Multi-tracer PET Study

scientific article published on 21 March 2022

Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia

scientific article published on 29 November 2017

Atypical parkinsonism due to a D202N Gerstmann‐Sträussler‐Scheinker prion protein mutation: First in vivo diagnosed case ⬇️

scientific article published on February 1, 2013

Basic pathologies of neurodegenerative dementias and their relevance for state-of-the-art molecular imaging studies

scientific article published on March 2008

Beta amyloid in Alzheimer's disease: increased deposition in brain is reflected in reduced concentration in cerebrospinal fluid

scientific article published on 06 March 2009

Characterization of SnO2-based (68)Ge/ (68)Ga generators and (68)Ga-DOTATATE preparations: radionuclide purity, radiochemical yield and long-term constancy

scientific article published on 24 July 2014

Clinical Experience with 18F-Labeled Small Molecule Inhibitors of Prostate-Specific Membrane Antigen

scientific article published on 23 January 2017

Clinical utility of FDG PET in Parkinson's disease and atypical parkinsonism associated with dementia

scientific article published on 19 May 2018

Combined PET/MR: Where are we now? Summary report of the second international workshop on PET/MR imaging April 8-12, 2013, Tubingen, Germany

scientific article published on June 2014

Comparison of 18F-T807 and 18F-THK5117 PET in a Mouse Model of Tau Pathology.

scientific article

Comparison of [(18)F]DCFPyL and [ (68)Ga]Ga-PSMA-HBED-CC for PSMA-PET Imaging in Patients with Relapsed Prostate Cancer

scientific article published on August 2015

Concept of functional imaging of memory decline in Alzheimer's disease

scientific article

Development and evaluation of compounds for imaging of beta-amyloid plaque by means of positron emission tomography

scientific article published on March 2008

Developments in oncological positron emission tomography/computed tomography assessment

scientific article published on December 2015

Diagnosis of Alzheimer's disease with [18F]PET in mild and asymptomatic stages

scientific article published on January 2009

Diagnostic Value of Subjective Memory Complaints Assessed with a Single Item in Dominantly Inherited Alzheimer's Disease: Results of the DIAN Study

scientific article

Dopamine metabolism of the nucleus accumbens and fronto-striatal connectivity modulate impulse control

scientific article published on 01 March 2019

Early-onset and robust amyloid pathology in a new homozygous mouse model of Alzheimer's disease

scientific article

Early-phase [18F]PI-2620 tau-PET imaging as a surrogate marker of neuronal injury

scientific article published on 21 April 2020

Editorial: Utilization of Hybrid PET/MR in Neuroimaging

scientific article published on July 2015

Effects of a 6-month cognitive intervention on brain metabolism in patients with amnestic MCI and mild Alzheimer's disease

scientific article

Effects of a 6-month cognitive intervention program on brain metabolism in amnestic mild cognitive impairment and mild Alzheimer's disease

scientific article published in January 2011

Effects of donepezil on cortical metabolic response to activation during (18)FDG-PET in Alzheimer's disease: a double-blind cross-over trial

scientific article published in June 2006

Erratum to: The need of standardization and of large clinical studies in an emerging indication of [18 F]FDG PET: the autoimmune encephalitis.

scientific article published on 16 December 2016

Extended postinterventional tumor necrosis-implication for outcome in liver transplant patients with advanced HCC.

scientific article

FDG and Amyloid PET in Cognitively Normal Individuals at Risk for Late-Onset Alzheimer's Disease

scientific article

FIBT versus florbetaben and PiB: a preclinical comparison study with amyloid-PET in transgenic mice

scientific article

First clinical experience with integrated whole-body PET/MR: comparison to PET/CT in patients with oncologic diagnoses

scientific article published on 25 April 2012

Gaussian Mixture Models and Model Selection for [18F] Fluorodeoxyglucose Positron Emission Tomography Classification in Alzheimer's Disease

scientific article published on January 2014

German Multicenter Study Investigating 177Lu-PSMA-617 Radioligand Therapy in Advanced Prostate Cancer Patients

scientific article

German guidelines for brain tumour imaging by PET and SPECT using labelled amino acids ⬇️

scientific article published on July 14, 2011

Imaging frontotemporal lobar degeneration

scientific article

Imaging of amyloid plaques and cerebral glucose metabolism in semantic dementia and Alzheimer's disease

scientific article published on 21 September 2007

Impact of PET/CT image reconstruction methods and liver uptake normalization strategies on quantitative image analysis

scientific article published on 18 August 2015

Impact of tau and amyloid burden on glucose metabolism in Alzheimer's disease

scientific article published on 20 October 2016

Impaired cross-modal inhibition in Alzheimer disease

scientific article

Impulsivity is Associated with Increased Metabolism in the Fronto-Insular Network in Parkinson's Disease

scientific article

Increased intrinsic brain activity in the striatum reflects symptom dimensions in schizophrenia

scientific article published on 12 January 2012

Joint EANM/EANO/RANO practice guidelines/SNMMI procedure standards for imaging of gliomas using PET with radiolabelled amino acids and [18F]FDG: version 1.0.

scientific article published on 5 December 2018

Kinetic modelling of [11C]flumazenil using data-driven methods

scientific article

LRP-1 polymorphism is associated with global and regional amyloid load in Alzheimer's Disease in humans in-vivo

scientific article published on 05 February 2014

Metabolic connectivity mapping reveals effective connectivity in the resting human brain

scientific article

Metabolic networks underlying cognitive reserve in prodromal Alzheimer disease: a European Alzheimer disease consortium project

scientific article

Mild cognitive impairment with suspected nonamyloid pathology (SNAP): Prediction of progression

scientific article

Molecular Imaging and Precision Medicine in Dementia and Movement Disorders

scientific article published on 5 October 2016

Monitoring Treatment Response to Erlotinib in EGFR-mutated Non-small-cell Lung Cancer Brain Metastases Using Serial O-(2-[18F]fluoroethyl)-L-tyrosine PET

scientific article published on 05 November 2018

Motor impairment and compensation in a hemiparkinsonian rat model: correlation between dopamine depletion severity, cerebral metabolism and gait patterns

scientific article published on 23 August 2017

Multicenter standardized 18F-FDG PET diagnosis of mild cognitive impairment, Alzheimer's disease, and other dementias

scientific article published on 20 February 2008

Multimodal imaging in Alzheimer's disease: validity and usefulness for early detection

scientific article published on 26 August 2015

Multivariate and univariate neuroimaging biomarkers of Alzheimer's disease

scientific article published on 14 February 2008

Neuro-cognitive mechanisms of simultanagnosia in patients with posterior cortical atrophy

scientific article

Neuronal dysfunction and disconnection of cortical hubs in non-demented subjects with elevated amyloid burden ⬇️

scientific article

PET imaging of gliomas using novel tracers: a sleeping beauty waiting to be kissed

scientific article

PET/MRI for neurologic applications

scientific article

Perspective on future role of biological markers in clinical therapy trials of Alzheimer's disease: a long-range point of view beyond 2020.

scientific article

Prefrontal hypometabolism in Alzheimer disease is related to longitudinal amyloid accumulation in remote brain regions

scientific article published on 12 February 2015

Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage

scientific article published on 17 February 2015

Prevalence of abnormal Alzheimer's disease biomarkers in patients with subjective cognitive decline: cross-sectional comparison of three European memory clinic samples

scholarly article by Steffen Wolfsgruber et al published 17 January 2019 in Alzheimers Research & Therapy

Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis

scientific article published in May 2015

Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis

scientific article published on May 2015

Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease

scientific article published on 27 March 2018

Prognostic value of Alzheimer's biomarkers in mild cognitive impairment: the effect of age at onset

scientific article published on 02 July 2019

Progression of cerebral amyloid load is associated with the apolipoprotein E ε4 genotype in Alzheimer's disease

scientific article

Prostate-Specific Membrane Antigen-Targeted Radiohalogenated PET and Therapeutic Agents for Prostate Cancer

scientific article published on October 2016

Reference cluster normalization improves detection of frontotemporal lobar degeneration by means of FDG-PET.

scientific article

Regional Expansion of Hypometabolism in Alzheimer's Disease Follows Amyloid Deposition with Temporal Delay ⬇️

scientific article published on June 15, 2011

Resting-State Connectivity of the Left Frontal Cortex to the Default Mode and Dorsal Attention Network Supports Reserve in Mild Cognitive Impairment

scientific article published on 7 August 2017

Resting-state functional reorganization in Parkinson's disease: An activation likelihood estimation meta-analysis

scientific article

SPECT/CT.

scientific article published on 16 July 2008

Selective changes of resting-state networks in individuals at risk for Alzheimer's disease

scientific article

Small-animal PET imaging of amyloid-beta plaques with [11C]PiB and its multi-modal validation in an APP/PS1 mouse model of Alzheimer's disease

scientific article

Structural and Functional Magnetic Resonance Imaging: Mild Cognitive Impairment and Alzheimer Disease

scientific article published on 30 August 2013

Successful Yttrium-90 Microsphere Radioembolization for Hepatic Metastases of Prostate Cancer

scientific article published on May 2017

Tau-imaging in neurodegeneration

scientific article published on 05 August 2017

The Functional Networks of Prepulse Inhibition: Neuronal Connectivity Analysis Based on FDG-PET in Awake and Unrestrained Rats.

scientific article

The Usefulness of Amyloid Imaging in Predicting the Clinical Outcome After Two Years in Subjects with Mild Cognitive Impairment ⬇️

scientific article published on January 1, 2013

The frequency and influence of dementia risk factors in prodromal Alzheimer's disease

scientific article published on 08 April 2017

The lower hippocampus global connectivity, the higher its local metabolism in Alzheimer disease

scientific article

The need of standardization and of large clinical studies in an emerging indication of [18F]FDG PET: the autoimmune encephalitis

scientific article published on 6 December 2016

Uptake in non-affected bone tissue does not differ between [18F]-DCFPyL and [68Ga]-HBED-CC PSMA PET/CT

scientific article published in PLoS ONE

Voxel-Based Analysis of Amyloid-Burden Measured with [11C]PiB PET in a Double Transgenic Mouse Model of Alzheimer’s Disease ⬇️

scientific article published on October 1, 2013

Within-patient correspondence of amyloid-β and intrinsic network connectivity in Alzheimer's disease

scientific article

Workflow and scan protocol considerations for integrated whole-body PET/MRI in oncology

scientific article

[Dopamine Transporter SPECT with I-123 labelled FP-CIT (DaTSCANTM)]

scientific article published on 15 February 2019

List of works by Alexander Drzezga

A European multicentre PET study of fibrillar amyloid in Alzheimer's disease

A Novel (18)F-Labeled Imidazo[2,1-b]benzothiazole (IBT) for High-Contrast PET Imaging of β-Amyloid Plaques

A new integrative model of cerebral activation, deactivation and default mode function in Alzheimer's disease

A perspective on the future role of brain pet imaging in exercise science

A systematic review on the applications of resting-state fMRI in Parkinson's disease: Does dopamine replacement therapy play a role?

AMYPAD Diagnostic and Patient Management Study: Rationale and design

Aberrant intrinsic connectivity of hippocampus and amygdala overlap in the fronto-insular and dorsomedial-prefrontal cortex in major depressive disorder

Ablative Radioiodtherapie bei niedrigem und intermediärem Rezidivrisiko. Höhere Überlebensrate beim Schilddrüsenkarzinom

Amyloid-PET and 18F-FDG-PET in the diagnostic investigation of Alzheimer's disease and other dementias

Amyloid-plaque imaging in early and differential diagnosis of dementia

Assessment of 18F-PI-2620 as a Biomarker in Progressive Supranuclear Palsy

Assessment of the In Vivo Relationship Between Cerebral Hypometabolism, Tau Deposition, TSPO Expression, and Synaptic Density in a Tauopathy Mouse Model: a Multi-tracer PET Study

Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia

Atypical parkinsonism due to a D202N Gerstmann‐Sträussler‐Scheinker prion protein mutation: First in vivo diagnosed case ⬇️

Basic pathologies of neurodegenerative dementias and their relevance for state-of-the-art molecular imaging studies

Beta amyloid in Alzheimer's disease: increased deposition in brain is reflected in reduced concentration in cerebrospinal fluid

Characterization of SnO2-based (68)Ge/ (68)Ga generators and (68)Ga-DOTATATE preparations: radionuclide purity, radiochemical yield and long-term constancy

Clinical Experience with 18F-Labeled Small Molecule Inhibitors of Prostate-Specific Membrane Antigen

Clinical utility of FDG PET in Parkinson's disease and atypical parkinsonism associated with dementia

Combined PET/MR: Where are we now? Summary report of the second international workshop on PET/MR imaging April 8-12, 2013, Tubingen, Germany

Comparison of 18F-T807 and 18F-THK5117 PET in a Mouse Model of Tau Pathology.

Comparison of [(18)F]DCFPyL and [ (68)Ga]Ga-PSMA-HBED-CC for PSMA-PET Imaging in Patients with Relapsed Prostate Cancer

Concept of functional imaging of memory decline in Alzheimer's disease

Development and evaluation of compounds for imaging of beta-amyloid plaque by means of positron emission tomography

Developments in oncological positron emission tomography/computed tomography assessment

Diagnosis of Alzheimer's disease with [18F]PET in mild and asymptomatic stages

Diagnostic Value of Subjective Memory Complaints Assessed with a Single Item in Dominantly Inherited Alzheimer's Disease: Results of the DIAN Study

Dopamine metabolism of the nucleus accumbens and fronto-striatal connectivity modulate impulse control

Early-onset and robust amyloid pathology in a new homozygous mouse model of Alzheimer's disease

Early-phase [18F]PI-2620 tau-PET imaging as a surrogate marker of neuronal injury

Editorial: Utilization of Hybrid PET/MR in Neuroimaging

Effects of a 6-month cognitive intervention on brain metabolism in patients with amnestic MCI and mild Alzheimer's disease

Effects of a 6-month cognitive intervention program on brain metabolism in amnestic mild cognitive impairment and mild Alzheimer's disease

Effects of donepezil on cortical metabolic response to activation during (18)FDG-PET in Alzheimer's disease: a double-blind cross-over trial

Erratum to: The need of standardization and of large clinical studies in an emerging indication of [18 F]FDG PET: the autoimmune encephalitis.

Extended postinterventional tumor necrosis-implication for outcome in liver transplant patients with advanced HCC.

FDG and Amyloid PET in Cognitively Normal Individuals at Risk for Late-Onset Alzheimer's Disease

FIBT versus florbetaben and PiB: a preclinical comparison study with amyloid-PET in transgenic mice

First clinical experience with integrated whole-body PET/MR: comparison to PET/CT in patients with oncologic diagnoses

Gaussian Mixture Models and Model Selection for [18F] Fluorodeoxyglucose Positron Emission Tomography Classification in Alzheimer's Disease

German Multicenter Study Investigating 177Lu-PSMA-617 Radioligand Therapy in Advanced Prostate Cancer Patients

German guidelines for brain tumour imaging by PET and SPECT using labelled amino acids ⬇️

Imaging frontotemporal lobar degeneration

Imaging of amyloid plaques and cerebral glucose metabolism in semantic dementia and Alzheimer's disease

Impact of PET/CT image reconstruction methods and liver uptake normalization strategies on quantitative image analysis

Impact of tau and amyloid burden on glucose metabolism in Alzheimer's disease

Impaired cross-modal inhibition in Alzheimer disease

Impulsivity is Associated with Increased Metabolism in the Fronto-Insular Network in Parkinson's Disease

Increased intrinsic brain activity in the striatum reflects symptom dimensions in schizophrenia

Joint EANM/EANO/RANO practice guidelines/SNMMI procedure standards for imaging of gliomas using PET with radiolabelled amino acids and [18F]FDG: version 1.0.

Kinetic modelling of [11C]flumazenil using data-driven methods

LRP-1 polymorphism is associated with global and regional amyloid load in Alzheimer's Disease in humans in-vivo

Metabolic connectivity mapping reveals effective connectivity in the resting human brain

Metabolic networks underlying cognitive reserve in prodromal Alzheimer disease: a European Alzheimer disease consortium project

Mild cognitive impairment with suspected nonamyloid pathology (SNAP): Prediction of progression

Molecular Imaging and Precision Medicine in Dementia and Movement Disorders

Monitoring Treatment Response to Erlotinib in EGFR-mutated Non-small-cell Lung Cancer Brain Metastases Using Serial O-(2-[18F]fluoroethyl)-L-tyrosine PET

Motor impairment and compensation in a hemiparkinsonian rat model: correlation between dopamine depletion severity, cerebral metabolism and gait patterns

Multicenter standardized 18F-FDG PET diagnosis of mild cognitive impairment, Alzheimer's disease, and other dementias

Multimodal imaging in Alzheimer's disease: validity and usefulness for early detection

Multivariate and univariate neuroimaging biomarkers of Alzheimer's disease

Neuro-cognitive mechanisms of simultanagnosia in patients with posterior cortical atrophy

Neuronal dysfunction and disconnection of cortical hubs in non-demented subjects with elevated amyloid burden ⬇️

PET imaging of gliomas using novel tracers: a sleeping beauty waiting to be kissed

PET/MRI for neurologic applications

Perspective on future role of biological markers in clinical therapy trials of Alzheimer's disease: a long-range point of view beyond 2020.

Prefrontal hypometabolism in Alzheimer disease is related to longitudinal amyloid accumulation in remote brain regions

Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage

Prevalence of abnormal Alzheimer's disease biomarkers in patients with subjective cognitive decline: cross-sectional comparison of three European memory clinic samples

Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis

Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis

Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease

Prognostic value of Alzheimer's biomarkers in mild cognitive impairment: the effect of age at onset

Progression of cerebral amyloid load is associated with the apolipoprotein E ε4 genotype in Alzheimer's disease

Prostate-Specific Membrane Antigen-Targeted Radiohalogenated PET and Therapeutic Agents for Prostate Cancer

Reference cluster normalization improves detection of frontotemporal lobar degeneration by means of FDG-PET.

Regional Expansion of Hypometabolism in Alzheimer's Disease Follows Amyloid Deposition with Temporal Delay ⬇️

Resting-State Connectivity of the Left Frontal Cortex to the Default Mode and Dorsal Attention Network Supports Reserve in Mild Cognitive Impairment

Resting-state functional reorganization in Parkinson's disease: An activation likelihood estimation meta-analysis