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List of works by Johanna Schleutker

A Finnish founder mutation in RAD51D: analysis in breast, ovarian, prostate, and colorectal cancer

scientific article

A Large-Scale Analysis of Genetic Variants within Putative miRNA Binding Sites in Prostate Cancer

scientific article

A combined genomewide linkage scan of 1,233 families for prostate cancer-susceptibility genes conducted by the international consortium for prostate cancer genetics

scientific article

A genetic epidemiological study of hereditary prostate cancer (HPC) in Finland: frequent HPCX linkage in families with late-onset disease

scientific article

A genetic risk score to guide age-specific, personalized prostate cancer screening

A genetic risk score to personalize prostate cancer screening, applied to population data

scientific article published on 24 June 2020

A genetic variant near GATA3 implicated in inherited susceptibility and etiology of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS).

scientific article published on 28 June 2017

A major locus for hereditary prostate cancer in Finland: localization by linkage disequilibrium of a haplotype in the HPCX region

scientific article published on 20 May 2005

A major locus for hereditary prostate cancer in Finland: localization by linkage disequilibrium of a haplotype in the HPCX region

scholarly article by Agnes B. Baffoe-Bonnie et al published 22 October 2005 in Human Genetics

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

scientific article published on 14 September 2014

A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease

scientific article

A missense substitution A49T in the steroid 5-alpha-reductase gene (SRD5A2) is not associated with prostate cancer in Finland

scientific article

A recurrent mutation in PALB2 in Finnish cancer families.

scientific article

AA9int: SNP interaction pattern search using non-hierarchical additive model set

ANO7 is associated with aggressive prostate cancer

scientific article published on 22 September 2018

ANO7 rs77559646 Is Associated With First-line Docetaxel Treatment Response in Metastatic Castration-resistant Prostate Cancer

scientific article published on 01 October 2019

ARLTS1 and prostate cancer risk--analysis of expression and regulation

scientific article

ARLTS1 germline variants and the risk for breast, prostate, and colorectal cancer

scientific article

Alcohol consumption and prostate cancer incidence and progression: A Mendelian randomisation study

scientific article published on 19 September 2016

An expressed retrogene of the master embryonic stem cell gene POU5F1 is associated with prostate cancer susceptibility

scientific article

Analysis of Xq27-28 linkage in the international consortium for prostate cancer genetics (ICPCG) families ⬇️

scientific article published on June 19, 2012

Androgen receptor CAG polymorphism and prostate cancer risk

scholarly article by Nina Mononen et al published 3 July 2002 in Human Genetics

Androgen receptor gene alterations and chromosomal gains and losses in prostate carcinomas appearing during finasteride treatment for benign prostatic hyperplasia

scientific article published on 01 November 1999

Androgen receptor gene mutations in hormone-refractory prostate cancer

scientific article published on 01 December 1999

Assessing interactions of two loci (rs4242382 and rs10486567) in familial prostate cancer: statistical evaluation of epistasis

scientific article

Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization: Genetic variants as instruments for circulating levels

scientific article published on 26 May 2016

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

scientific article published on 11 June 2018

Association analysis of 9,560 prostate cancer cases from the International Consortium of Prostate Cancer Genetics confirms the role of reported prostate cancer associated SNPs for familial disease

scientific article published on 26 October 2013

Association of E-cadherin germ-line alterations with prostate cancer

scientific article published on 01 November 2001

Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

scientific article published on 7 April 2016

Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

scholarly article published in Nature Genetics

Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

scholarly article published in Nature Genetics

Author Correction: Germline variation at 8q24 and prostate cancer risk in men of European ancestry

scientific article published in Nature Communications

BRCA1 and BRCA2 mutations have no major role in predisposition to prostate cancer in Finland

scientific article

Biology and Clinical Implications of the 19q13 Aggressive Prostate Cancer Susceptibility Locus

Blood lipids and prostate cancer: a Mendelian randomization analysis

scientific article published on 19 March 2016

C-reactive protein haplotype is associated with high PSA as a marker of metastatic prostate cancer but not with overall cancer risk

scientific article published on 12 May 2009

CHEK2 mutations in primary glioblastomas.

scientific article

CHEK2 variants associate with hereditary prostate cancer

scientific article published on November 2003

Case-control analysis of truncating mutations in DNA damage response genes connects TEX15 and FANCD2 with hereditary breast cancer susceptibility

scientific article

Chromosomes 4 and 8 implicated in a genome wide SNP linkage scan of 762 prostate cancer families collected by the ICPCG

scientific article published on 11 July 2011

Circulating Metabolic Biomarkers of Screen-Detected Prostate Cancer in the ProtecT Study

scientific article published on 23 October 2018

Clinical and histopathological characteristics of familial prostate cancer in Finland

scientific article published on 20 April 2011

Combined Genome-Wide Scan for Prostate Cancer Susceptibility Genes

article

Compelling evidence for a prostate cancer gene at 22q12.3 by the International Consortium for Prostate Cancer Genetics

scientific article published on 03 May 2007

Contribution of ARLTS1 Cys148Arg (T442C) variant with prostate cancer risk and ARLTS1 function in prostate cancer cells

scientific article

Detection of subclinical cancers by prostate-specific antigen screening in asymptomatic men from high-risk prostate cancer families

scientific article published on 01 June 1999

ELAC2/HPC2 involvement in hereditary and sporadic prostate cancer

scientific article (publication date: 15 August 2001)

EPHB2 germline variants in patients with colorectal cancer or hyperplastic polyposis

scientific article published in June 2006

Evaluation of the RHINO gene for breast cancer predisposition in Finnish breast cancer families

scientific article published on 22 February 2014

Evidence for a prostate cancer susceptibility locus on the X chromosome.

article

Exclusion map of Salla disease: attempts to localize the disease gene using a computer program ⬇️

scientific article published on 01 January 1992

Exclusion of the 750-kb genetically unstable region at Xq27 as a candidate locus for prostate malignancy in HPCX1-linked families.

scientific article

Exome sequencing identifies FANCM as a susceptibility gene for triple-negative breast cancer

scientific article

Expressional profiling of prostate cancer risk SNPs at 11q13.5 identifies DGAT2 as a new target gene

scientific article

FANCM mutation c.5791C>T is a risk factor for triple-negative breast cancer in the Finnish population

scientific article published on 12 July 2017

Fine mapping of 11q13.5 identifies regions associated with prostate cancer and prostate cancer death

scientific article published on 02 July 2013

Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression

scientific article published on 27 March 2013

Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression.

scientific article

Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants.

scientific article published on 11 June 2018

Fine-mapping the 2q37 and 17q11.2-q22 loci for novel genes and sequence variants associated with a genetic predisposition to prostate cancer

scientific article

Fine-mapping the HOXB region detects common variants tagging a rare coding allele: evidence for synthetic association in prostate cancer

scientific article

Finnish Fanconi anemia mutations and hereditary predisposition to breast and prostate cancer

Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array

scientific article published on 13 February 2018

Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array

scientific article

Genetic association analysis of the RTK/ERK pathway with aggressive prostate cancer highlights the potential role of CCND2 in disease progression

scientific article

Genetic changes in familial prostate cancer by comparative genomic hybridization

scientific article published on 01 February 2001

Genetic heterogeneity in Finnish hereditary prostate cancer using ordered subset analysis

scientific article published on 5 September 2012

Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types

scientific article published in September 2016

Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility

scientific article published on 20 September 2009

Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21.

scientific article published on 4 June 2016

Genome-wide association study of prostate cancer-specific survival

scientific article published on 25 August 2015

Genome-wide linkage analysis of 1,233 prostate cancer pedigrees from the International Consortium for Prostate Cancer Genetics using novel sumLINK and sumLOD analyses

scientific article

Genome-wide linkage scan for prostate cancer susceptibility in Finland: evidence for a novel locus on 2q37.3 and confirmation of signal on 17q21-q22.

scientific article

Genome-wide scan for linkage in finnish hereditary prostate cancer (HPC) families identifies novel susceptibility loci at 11q14 and 3p25-26.

scientific article

Germ-line alterations in MSR1 gene and prostate cancer risk

scientific article published on 01 November 2003

Germline EMSY sequence alterations in hereditary breast cancer and ovarian cancer families

scientific article published on 24 July 2017

Germline alterations of the RNASEL gene, a candidate HPC1 gene at 1q25, in patients and families with prostate cancer

scientific article published on 8 April 2002

Germline copy number variation analysis in Finnish families with hereditary prostate cancer

scientific article published on 10 November 2015

Germline mutation analysis of the androgen receptor gene in Finnish patients with prostate cancer

scientific article

Germline mutations in the ribonuclease L gene in families showing linkage with HPC1

scientific article (publication date: February 2002)

Germline variants in IL4, MGMT and AKT1 are associated with prostate cancer-specific mortality: An analysis of 12,082 prostate cancer cases

scientific article published on 3 January 2018

Germline variation at 8q24 and prostate cancer risk in men of European ancestry

scientific article published in Nature Communications

HOXB13 G84E mutation in Finland: population-based analysis of prostate, breast, and colorectal cancer risk

scientific article published on 4 January 2013

HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG).

scientific article published on 12 October 2012

Hemochromatosis gene mutations among Finnish male breast and prostate cancer patients

scientific article published on 01 January 2006

Hereditary prostate cancer in Finland: fine-mapping validates 3p26 as a major predisposition locus

scholarly article by Annika R�kman et al published 11 November 2004 in Human Genetics

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array

scientific article

Identification of an aggressive prostate cancer predisposing variant at 11q13.

scientific article published on 6 January 2011

Identification of germline MLH1 alterations in familial prostate cancer

scientific article published on 11 September 2006

Identification of seven new prostate cancer susceptibility loci through a genome-wide association study

scientific article

Incidence of cancer in finnish families with clinically aggressive and nonaggressive prostate cancer

scientific article published on 20 October 2009

Inherited DNA Repair Gene Mutations in Men with Lethal Prostate Cancer

scientific article published on 14 March 2020

Investigating the possible causal role of coffee consumption with prostate cancer risk and progression using Mendelian randomization analysis

scientific article published on 14 October 2016

KLF6 IVS1 -27G>A Variant and the Risk of Prostate Cancer in Finland

scientific article published on 17 November 2006

Kruppel-like factor 6 germ-line mutations are infrequent in Finnish hereditary prostate cancer

scientific article published in August 2004

Lactase persistence, dietary intake of milk, and the risk for prostate cancer in Sweden and Finland

scientific article

Linkage of a new mutation in the proteolipid protein (PLP) gene to Pelizaeus-Merzbacher disease (PMD) in a large Finnish kindred ⬇️

scientific article published on June 1, 1993

MiRNA Profiles in Lymphoblastoid Cell Lines of Finnish Prostate Cancer Families

scientific article published on 28 May 2015

Microseminoprotein-Beta Expression in Different Stages of Prostate Cancer

scientific article

Multiple novel prostate cancer predisposition loci confirmed by an international study: the PRACTICAL Consortium

scientific article

Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

scientific article published on 29 May 2015

Mutational analysis of SPANX genes in families with X-linked prostate cancer

scientific article published on 01 June 2007

NMD and microRNA expression profiling of the HPCX1 locus reveal MAGEC1 as a candidate prostate cancer predisposition gene

scientific article

Nationwide cancer family ascertainment using Finnish Cancer Registry data on family names and places of birth for 35,761 prostate cancer patients

scientific article

New paraoxonase 1 polymorphism I102V and the risk of prostate cancer in Finnish men.

scientific article

No fumarate hydratase (FH) mutations in hereditary prostate cancer

scientific article published in March 2003

Nonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer

scientific article published on 8 August 2004

Nordic collaborative study of the BARD1 Cys557Ser allele in 3956 patients with cancer: enrichment in familial BRCA1/BRCA2 mutation-negative breast cancer but not in other malignancies

scientific article published on 06 July 2006

Oligogenic basis of sporadic ALS: The example of p.Ala90Val mutation

scientific article published on 23 April 2019

PALB2 variants in hereditary and unselected Finnish prostate cancer cases

scientific article

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

scientific article published in December 2016

Physical and transcript map of the hereditary prostate cancer region at xq27.

scientific article

Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts

scientific article published on 10 January 2018

Polymorphisms in androgen signaling pathway predisposing to prostate cancer ⬇️

scientific article published on July 18, 2011

Polymorphisms in genes involved in androgen pathways as risk factors for prostate cancer

scientific article published on 23 February 2009

Polymorphisms of Genes Involved in Glucose and Energy Metabolic Pathways and Prostate Cancer: Interplay with Metformin

scientific article published on 26 March 2015

Polyunsaturated fatty acids and prostate cancer risk: a Mendelian randomisation analysis from the PRACTICAL consortium

scientific article published on 4 August 2016

Pooled genome linkage scan of aggressive prostate cancer: results from the International Consortium for Prostate Cancer Genetics

scientific article published on 25 August 2006

Post hoc Analysis for Detecting Individual Rare Variant Risk Associations Using Probit Regression Bayesian Variable Selection Methods in Case-Control Sequencing Studies

scientific article published on 17 June 2016

Prediction of individual genetic risk to prostate cancer using a polygenic score

scientific article published on 14 July 2015

Profiling Genetic Variation along the Androgen Biosynthesis and Metabolism Pathways Implicates Several Single Nucleotide Polymorphisms and Their Combinations as Prostate Cancer Risk Factors

scholarly article by Nina Mononen et al published 15 January 2006 in Cancer Research

Prostate cancer risk prediction using a polygenic risk score

scientific article published on 13 October 2020

Prostate cancer risk regions at 8q24 and 17q24 are differentially associated with somatic TMPRSS2:ERG fusion status

scientific article

Prostate cancer screening using risk stratification based on a multi-state model of genetic variants

scientific article published on 14 February 2015

Pubertal development and prostate cancer risk: Mendelian randomization study in a population-based cohort

scientific article published on 4 April 2016

Publisher Correction: Shared heritability and functional enrichment across six solid cancers

scientific article published on 23 September 2019

RAD51B in Familial Breast Cancer

scientific article

RAD51C is a susceptibility gene for ovarian cancer

article

REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants

scientific article published on 21 September 2016

Recurrent moderate-risk mutations in Finnish breast and ovarian cancer patients

scientific article published on 25 April 2019

Reducing overdiagnosis by polygenic risk-stratified screening: findings from the Finnish section of the ERSPC.

scientific article

Relatives of prostate cancer patients have an increased risk of prostate and stomach cancers: a population-based, cancer registry study in Finland

scientific article published on 01 April 2001

Risk Analysis of Prostate Cancer in PRACTICAL, a Multinational Consortium, Using 25 Known Prostate Cancer Susceptibility Loci

scientific article published on 2 April 2015

Risk Prediction of Prostate Cancer with Single Nucleotide Polymorphisms (SNPs) and Prostate-Specific Antigen (PSA)

scientific article published on 01 March 2019

Role of the Nijmegen breakage syndrome 1 gene in familial and sporadic prostate cancer

scientific article published in May 2006

Screening for BRCA1, BRCA2, CHEK2, PALB2, BRIP1, RAD50, and CDH1 mutations in high-risk Finnish BRCA1/2-founder mutation-negative breast and/or ovarian cancer individuals ⬇️

scientific article

Screening of Finnish RAD51C founder mutations in prostate and colorectal cancer patients

scientific article

Segregation analysis of 1,546 prostate cancer families in Finland shows recessive inheritance

scientific article

Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study

scientific article

ShAn: An easy-to-use tool for interactive and integrated variant annotation

scientific article published on 07 July 2020

Shared heritability and functional enrichment across six solid cancers

scientific article published in Nature Communications

Shared heritability and functional enrichment across six solid cancers

Synergistic Interaction of HOXB13 and CIP2A Predisposes to Aggressive Prostate Cancer

scientific article published on 04 September 2018

The CHEK2 Variant C.349A>G Is Associated with Prostate Cancer Risk and Carriers Share a Common Ancestor

scientific article published on 04 November 2020

The effect of sample size on polygenic hazard models for prostate cancer

scientific article published on 08 June 2020

The effects of height and BMI on prostate cancer incidence and mortality: a Mendelian randomization study in 20,848 cases and 20,214 controls from the PRACTICAL consortium

scientific article

The interaction of CYP3A5 polymorphisms along the androgen metabolism pathway in prostate cancer

scientific article

The interactome of the prostate-specific protein Anoctamin 7

scientific article published on 06 March 2020

Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

scientific article published in January 2021

Two percent of Finnish prostate cancer patients have a germ-line mutation in the hormone-binding domain of the androgen receptor gene

scientific article published on 01 November 2000

Two-locus genome-wide linkage scan for prostate cancer susceptibility genes with an interaction effect

article

Two-stage Study of Familial Prostate Cancer by Whole-exome Sequencing and Custom Capture Identifies 10 Novel Genes Associated with the Risk of Prostate Cancer

scientific article published on 13 August 2020

Validation of prostate cancer risk-related loci identified from genome-wide association studies using family-based association analysis: evidence from the International Consortium for Prostate Cancer Genetics (ICPCG)

scientific article published on 25 December 2011

Whole-exome sequencing of Finnish hereditary breast cancer families

scientific article published on 26 October 2016

Whole-exome sequencing of Finnish patients with vascular cognitive impairment

scientific article published on 02 December 2020

[ Hereditary prostate cancer with gene location]

scientific article published on 01 January 1997

copy number variation analysis in familial BRCA1/2-negative Finnish breast and ovarian cancer

scientific article

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