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List of works by Iris Eke

3D cell cultures of human head and neck squamous cell carcinoma cells are radiosensitized by the focal adhesion kinase inhibitor TAE226.

scientific article

3D matrix-based cell cultures: Automated analysis of tumor cell survival and proliferation

scientific article published on 4 November 2015

53BP1/RIF1 signaling promotes cell survival after multifractionated radiotherapy

scientific article published on 01 February 2020

APPL proteins modulate DNA repair and radiation survival of pancreatic carcinoma cells by regulating ATM.

scientific article published on 24 April 2014

An essential role of integrin-linked kinase in the cellular radiosensitivity of normal fibroblasts during the process of cell adhesion and spreading.

scientific article published on November 2007

Antiproliferative effects of EGFR tyrosine kinase inhibition and radiation-induced genotoxic injury are attenuated by adhesion to fibronectin

scientific article published on 07 August 2006

Caveolin-1 mediated radioresistance of 3D grown pancreatic cancer cells

scientific article

Cetuximab attenuates its cytotoxic and radiosensitizing potential by inducing fibronectin biosynthesis

scientific article published on 15 August 2013

Comprehensive analysis of signal transduction in three-dimensional ECM-based tumor cell cultures

scientific article

Comprehensive molecular tumor profiling in radiation oncology: How it could be used for precision medicine

scientific article published on 29 January 2016

Cytotoxic properties of radionuclide-conjugated Cetuximab without and in combination with external irradiation in head and neck cancer cells in vitro.

scientific article published on 3 April 2014

Dual targeting of EGFR and focal adhesion kinase in 3D grown HNSCC cell cultures ⬇️

scientific article published on June 23, 2011

EGFR and β1-integrin targeting differentially affect colorectal carcinoma cell radiosensitivity and invasion

scientific article

EGFR/JIP-4/JNK2 signaling attenuates cetuximab-mediated radiosensitization of squamous cell carcinoma cells

scientific article

Enhanced radiosensitivity of head and neck squamous cell carcinoma cells by β1 integrin inhibition

scientific article

Exploiting Gene Expression Kinetics in Conventional Radiotherapy, Hyperfractionation, and Hypofractionation for Targeted Therapy.

scientific article published on 5 July 2016

Exploiting radiation-induced signaling to increase the susceptibility of resistant cancer cells to targeted drugs: AKT and mTOR inhibitors as an example

scientific article published on 11 August 2017

Expression of integrin-linked kinase is increased in differentiated cells

scientific article

Focal adhesion signaling and therapy resistance in cancer

scientific article published on 10 August 2014

Human head and neck squamous cell carcinoma cell lines are differentially radiosensitised by the honeybee product Propolis

scientific article published on 10 December 2010

Inactivation of HNSCC cells by 90Y-labeled cetuximab strictly depends on the number of induced DNA double-strand breaks

scientific article published on 23 January 2013

Integrin-linked kinase: Dispensable for radiation survival of three-dimensionally cultured fibroblasts

scientific article published on 01 October 2007

LIM-only protein FHL2 critically determines survival and radioresistance of pancreatic cancer cells

scientific article published on 23 April 2015

Long-term Tumor Adaptation after Radiotherapy: Therapeutic Implications for Targeting Integrins in Prostate Cancer

scientific article published on 24 July 2018

Microarray analysis of miRNA expression profiles following whole body irradiation in a mouse model

scientific article published on 19 June 2018

PINCH1 regulates Akt1 activation and enhances radioresistance by inhibiting PP1alpha

scientific article

Pharmacological inhibition of EGFR tyrosine kinase affects ILK-mediated cellular radiosensitization in vitro

scientific article published on November 2007

Radiation-Induced Fibrosis: Mechanisms and Opportunities to Mitigate. Report of an NCI Workshop, September 19, 2016.

scientific article published on 10 May 2017

Radiation-Induced Long Noncoding RNAs in a Mouse Model after Whole-Body Irradiation

scientific article published on 8 January 2018

Radiation-induced adaptive response: new potential for cancer treatment

scientific article published on 17 June 2020

Radiobiology goes 3D: How ECM and cell morphology impact on cell survival after irradiation ⬇️

scientific article published on June 23, 2011

Simultaneous β1 integrin-EGFR targeting and radiosensitization of human head and neck cancer

scientific article

Targeting FAK radiosensitizes 3-dimensional grown human HNSCC cells through reduced Akt1 and MEK1/2 signaling

scientific article

Targeting of the EGFR/β1 integrin connecting proteins PINCH1 and Nck2 radiosensitizes three-dimensional SCC cell cultures

scientific article published on 25 May 2015

Targeting of β1 integrins impairs DNA repair for radiosensitization of head and neck cancer cells.

scientific article published on 15 June 2015

The Future of Radiobiology.

scientific article published on 3 November 2017

The role of the focal adhesion protein PINCH1 for the radiosensitivity of adhesion and suspension cell cultures

scientific article

The small molecule inhibitor QLT0267 Radiosensitizes squamous cell carcinoma cells of the head and neck

scientific article

There's something about ILK.

scientific article

Three-dimensional cell growth confers radioresistance by chromatin density modification

scientific article

Three-dimensional invasion of human glioblastoma cells remains unchanged by X-ray and carbon ion irradiation in vitro

scientific article published on 15 August 2012

Workshop Report for Cancer Research: Defining the Shades of Gy: Utilizing the Biological Consequences of Radiotherapy in the Development of New Treatment Approaches-Meeting Viewpoint.

scientific article published on 23 April 2018

α integrin targeting for radiosensitization of three-dimensionally grown human head and neck squamous cell carcinoma cells

scientific article

β₁Integrin/FAK/cortactin signaling is essential for human head and neck cancer resistance to radiotherapy

scientific article

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