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List of works by Jørn W. Helge

2706 km cycling in 2 weeks: effects on cardiac function in 6 elderly male athletes.

scientific article

A Biological Age Model Designed for Health Promotion Interventions: Protocol for an Interdisciplinary Study for Model Development

scientific article published on 26 October 2020

A high carbohydrate diet remains the evidence based choice for elite athletes to optimise performance

scientific article

A maximal cycle test with good validity and high repeatability in adults of all ages.

scientific article published on 26 September 2014

A randomized double-blind study of testosterone replacement therapy or placebo in testicular cancer survivors with mild Leydig cell insufficiency (Einstein-intervention).

scientific article published on 3 July 2017

Actovegin, a non-prohibited drug increases oxidative capacity in human skeletal muscle.

scientific article

Acute exercise improves motor memory: exploring potential biomarkers.

scientific article published on 14 August 2014

Adaptation to a fat-rich diet: effects on endurance performance in humans.

scientific article

Adipose tissue mitochondrial respiration and lipolysis before and after a weight loss by diet and RYGB.

scientific article published on 4 September 2015

Adverse metabolic risk profiles in Greenlandic Inuit children compared to Danish children

scientific article published on 13 May 2013

Aerobic Exercise Performance and Muscle Strength in Statin Users-The LIFESTAT Study

scientific article published on 01 July 2019

Aerobic Exercise Training Increases Muscle Water Content in Obese Middle-Age Men

scientific article published on 01 May 2016

Aerobic and resistance exercise training reverses age-dependent decline in NAD+ salvage capacity in human skeletal muscle

scientific article published on 01 July 2019

An optimized histochemical method to assess skeletal muscle glycogen and lipid stores reveals two metabolically distinct populations of type I muscle fibers

scientific article

Anthropometry, DXA, and leptin reflect subcutaneous but not visceral abdominal adipose tissue on MRI in 197 healthy adolescents

scientific article published on 19 July 2017

Are blood flow and lipolysis in subcutaneous adipose tissue influenced by contractions in adjacent muscles in humans?

scientific article

Are substrate use during exercise and mitochondrial respiratory capacity decreased in arm and leg muscle in type 2 diabetes?

scientific article published on 25 April 2009

Arm and leg substrate utilization and muscle adaptation after prolonged low-intensity training.

scientific article published on 25 March 2010

Association between plasma leptin and blood pressure in two population-based samples of children and adolescents

Associations between vitamin D status and atherosclerosis among Inuit in Greenland

scientific article published in December 2017

Biomarkers of mitochondrial content in skeletal muscle of healthy young human subjects

article

Biphasic response of plasma endothelin-1 concentration to exhausting submaximal exercise in man

scientific article published on 01 July 1994

Blood temperature and perfusion to exercising and non-exercising human limbs.

scientific article published on 13 August 2015

Bone mineral density in lifelong trained male football players compared with young and elderly untrained men

Caffeine ingestion does not alter carbohydrate or fat metabolism in human skeletal muscle during exercise

scientific article published on 01 December 2000

Cardiac output and leg and arm blood flow during incremental exercise to exhaustion on the cycle ergometer

scientific article published on 28 June 2007

Cardiorespiratory fitness in 16 025 adults aged 18-91 years and associations with physical activity and sitting time.

scientific article published on 17 December 2015

Cardiovascular and metabolic health effects of team handball training in overweight women: Impact of prior experience

scientific article published on 07 November 2019

Central and peripheral hemodynamics in exercising humans: leg vs arm exercise

scientific article published in December 2015

Ceramide content is higher in type I compared to type II fibers in obesity and type 2 diabetes mellitus

scientific article published on 19 February 2012

Cerebral autoregulation dynamics in endurance-trained individuals.

scientific article published on 3 March 2011

Changes in physical activity in leisure time and the risk of myocardial infarction, ischemic heart disease, and all-cause mortality

scientific article published on 05 February 2012

Childhood hypo-adiponectinaemia but not hyper-leptinaemia is associated with insulin insensitivity 6 years later

scientific article published on 4 August 2009

Coenzyme Q10 does not improve peripheral insulin sensitivity in statin-treated men and women; the LIFESTAT study

scientific article published on 01 October 2018

Combined heart rate- and accelerometer-assessed physical activity energy expenditure and associations with glucose homeostasis markers in a population at high risk of developing diabetes: the ADDITION-PRO study

scientific article published on 11 June 2013

Comment on Chondronikola et al. Brown adipose tissue improves whole-body glucose homeostasis and insulin sensitivity in humans. Diabetes 2014;63:4089-4099.

scientific article published in June 2015

Comment on Režen et al. Expression changes in human skeletal muscle miRNAs following 10 days of bed rest in young healthy males. Acta Physiol 2014; 210: 655-666

scientific article published on 28 August 2014

Contraction-mediated glucose uptake is increased in men with impaired glucose tolerance.

scientific article published in February 2007

Correlates and predictors of obesity-specific quality of life of former participants of a residential intensive lifestyle intervention.

scientific article

Corrigendum to "Inflammatory biomarkers in patients in simvastatin treatment: No effect of co-enzyme Q10 supplementation" [Cytokine 113 (2019) 393-399]

scientific article published on 06 December 2019

Cryopreservation of human skeletal muscle impairs mitochondrial function

scientific article published on 01 May 2012

Determination and validation of peak fat oxidation in endurance-trained men using an upper body graded exercise test

scientific article published on 31 July 2019

Determination of the exercise intensity that elicits maximal fat oxidation in individuals with obesity.

scientific article

Diet and exercise reduce low-grade inflammation and macrophage infiltration in adipose tissue but not in skeletal muscle in severely obese subjects.

scientific article

Dietary habits, metabolic health and vitamin D status in Greenlandic children

scientific article published on 01 October 2019

Diurnal Variation of Maximal Fat-Oxidation Rate in Trained Male Athletes

scientific article published on 01 September 2019

Divergent effects of resistance and endurance exercise on plasma bile acids, FGF19, and FGF21 in humans

scientific article published on 09 August 2018

Do energy density and dietary fiber influence subsequent 5-year weight changes in adult men and women?

scientific article published in January 2006

Dual regulation of muscle glycogen synthase during exercise by activation and compartmentalization.

scientific article published on April 2009

Dynamic changes in DICER levels in adipose tissue control metabolic adaptations to exercise

scientific article published on 08 September 2020

Eccentric contractions affect muscle membrane phospholipid fatty acid composition in rats.

scientific article published in September 2001

Effect of a Web-based intervention to promote physical activity and improve health among physically inactive adults: a population-based randomized controlled trial

scientific article

Effect of gender on lipid-induced insulin resistance in obese subjects

scientific article published in January 2008

Effect of high-fat diets on exercise performance ⬇️

scientific article published on February 1, 1998

Effect of regional muscle location but not adiposity on mitochondrial biogenesis-regulating proteins.

scientific article published on 13 August 2015

Effect of training on muscle triacylglycerol and structural lipids: a relation to insulin sensitivity?

scientific article published in August 2003

Effects of 6-month aerobic interval training on skeletal muscle metabolism in middle-aged metabolic syndrome patients

scientific article published on 21 March 2017

Effects of an 8-weeks erythropoietin treatment on mitochondrial and whole body fat oxidation capacity during exercise in healthy males.

scientific article published on 26 September 2014

Effects of exercise training on mitochondrial function in patients with type 2 diabetes.

scientific article

Effects of immobilization and aerobic training on proteins related to intramuscular substrate storage and metabolism in young and older men

scientific article published in December 2015

Effects of one-legged high-intensity interval training on insulin-mediated skeletal muscle glucose homeostasis in patients with type 2 diabetes

scientific article published on 14 February 2019

Effects of physical training on endothelial function and limb blood flow in type 2 diabetes.

scientific article published on October 2007

Effects of small-sided recreational team handball training on mechanical muscle function, body composition and bone mineralization in untrained young adults-A randomized controlled trial

scientific article published on 18 November 2020

Endurance TrainingPer SeIncreases Metabolic Health in Young, Moderately Overweight Men

article

Erythropoietin treatment enhances muscle mitochondrial capacity in humans.

scientific article published on 13 March 2012

Ethnic differences in leptin and adiponectin levels between Greenlandic Inuit and Danish children

scientific article published on 07 August 2013

Exercise and training effects on ceramide metabolism in human skeletal muscle.

scientific article published in January 2004

Exercise increases sphingoid base-1-phosphate levels in human blood and skeletal muscle in a time- and intensity-dependent manner

scientific article published on 18 December 2014

Exercise interventions to prevent and manage type 2 diabetes: physiological mechanisms.

scientific article published on 09 September 2014

Fat oxidation at rest predicts peak fat oxidation during exercise and metabolic phenotype in overweight men.

scientific article published on 16 February 2010

Fat utilization during exercise: adaptation to a fat-rich diet increases utilization of plasma fatty acids and very low density lipoprotein-triacylglycerol in humans

scientific article

Fitness and health benefits of team handball training for young untrained women-A cross-disciplinary RCT on physiological adaptations and motivational aspects

article

Football training in men with prostate cancer undergoing androgen deprivation therapy: activity profile and short-term skeletal and postural balance adaptations

scientific article published on 30 November 2015

Football training over 5 years is associated with preserved femoral bone mineral density in men with prostate cancer

scientific article published on 12 July 2018

Four weeks one-leg training and high fat diet does not alter PPARalpha protein or mRNA expression in human skeletal muscle

scientific article published on 26 May 2007

GAPDH and β-actin protein decreases with aging, making Stain-Free technology a superior loading control in Western blotting of human skeletal muscle

scientific article published on 26 November 2014

Glucose homeostasis in statin users-The LIFESTAT study

scientific article published on 21 December 2018

Hepatic mitochondrial oxidative phosphorylation is normal in obese patients with and without type 2 diabetes

scientific article

High responders to resistance exercise training demonstrate differential regulation of skeletal muscle microRNA expression.

scientific article published on 28 October 2010

High-fat feeding inhibits exercise-induced increase in mitochondrial respiratory flux in skeletal muscle.

scientific article published on 17 March 2011

High-intensity interval training changes mitochondrial respiratory capacity differently in adipose tissue and skeletal muscle

scientific article published on 01 September 2018

High-intensity interval training improves insulin sensitivity in older individuals.

scientific article published on 2 December 2017

Higher muscle content of perilipin 5 and endothelial lipase protein in trained than untrained middle-aged men.

scientific article published on 8 October 2015

Human skeletal muscle ceramide content is not a major factor in muscle insulin sensitivity.

scientific article published on 6 May 2008

Hypoadiponectinemia in overweight children contributes to a negative metabolic risk profile 6 years later

scientific article

Immobilization increases interleukin-6, but not tumour necrosis factor-α, release from the leg during exercise in humans.

scientific article published on 9 November 2012

Impact of a fat-rich diet on endurance in man: role of the dietary period

scientific article published on 01 March 1998

Impact of data analysis methods for maximal fat oxidation estimation during exercise in sedentary adults

scientific article published on 28 March 2019

Impact of the growth hormone receptor exon 3 deletion gene polymorphism on glucose metabolism, lipids, and insulin-like growth factor-I levels during puberty.

scientific article published on 5 May 2009

Improved glucose tolerance after intensive life style intervention occurs without changes in muscle ceramide or triacylglycerol in morbidly obese subjects

scientific article published on 11 October 2010

Inability to match energy intake with energy expenditure at sustained near-maximal rates of energy expenditure in older men during a 14-d cycling expedition

scientific article

Increased fat oxidation and regulation of metabolic genes with ultraendurance exercise

scientific article published on 03 May 2007

Increased intrinsic mitochondrial function in humans with mitochondrial haplogroup H.

scientific article published in November 2013

Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes

scientific article published on 18 March 2011

Increased post-operative cardiopulmonary fitness in gastric bypass patients is explained by weight loss

scientific article published on 4 December 2015

Independent effects of endurance training and weight loss on peak fat oxidation in moderately overweight men: a randomized controlled trial

scientific article published on 22 January 2015

Inflammatory biomarkers in patients in Simvastatin treatment: No effect of co-enzyme Q10 supplementation

scientific article published on 30 October 2018

Influence of age on leptin induced skeletal muscle signalling

scientific article published on May 2014

Influence of exercise amount and intensity on long-term weight loss maintenance and skeletal muscle mitochondrial ROS production in humans

scientific article published on 21 January 2019

Influence of maximal fat oxidation on long-term weight loss maintenance in humans.

scientific article published on 25 May 2017

Influence of pre-exercise muscle glycogen content on exercise-induced transcriptional regulation of metabolic genes

scientific article

Insulin resistance and mitochondrial function in skeletal muscle.

scientific article published on 02 October 2012

Intake of total dietary sugar and fibre is associated with insulin resistance among Danish 8-10- and 14-16-year-old girls but not boys. European Youth Heart Studies I and II.

scientific article published on 18 March 2010

Interaction of training and diet on metabolism and endurance during exercise in man

scientific article published on 01 April 1996

Interleukin-18 in plasma and adipose tissue: effects of obesity, insulin resistance, and weight loss

scientific article published in October 2007

Interleukin-6 release is higher across arm than leg muscles during whole-body exercise

article

Interstitial glycerol concentrations in human skeletal muscle and adipose tissue during graded exercise.

scientific article published in April 2004

Is there plasticity in mitochondrial cristae density with endurance training?

scientific article published in May 2017

LIFESTAT - Living with statins: An interdisciplinary project on the use of statins as a cholesterol-lowering treatment and for cardiovascular risk reduction

scientific article

Leptin receptor 170 kDa (OB-R170) protein expression is reduced in obese human skeletal muscle: a potential mechanism of leptin resistance.

scientific article

Leydig cell dysfunction, systemic inflammation and metabolic syndrome in long-term testicular cancer survivors

scientific article published on 31 July 2017

Lifestyle intervention in the treatment of severe obesity

scientific article published in January 2006

Low-Grade Inflammation Is Not Present in Former Obese Males but Adipose Tissue Macrophage Infiltration Persists

scientific article published on 14 May 2020

Low-intensity training dissociates metabolic from aerobic fitness.

scientific article published on 12 March 2007

Low-intensity training increases peak arm VO2by enhancing both convective and diffusive O2delivery

scientific article published on 17 March 2014

Macrophage Area Content and Phenotype in Hepatic and Adipose Tissue in Patients with Obesity Undergoing Roux-en-Y Gastric Bypass

scientific article published on 18 September 2017

Maintained peak leg and pulmonary VO2 despite substantial reduction in muscle mitochondrial capacity

scientific article published on December 2015

Maintaining a clinical weight loss after intensive lifestyle intervention is the key to cardiometabolic health

scientific article published on 5 October 2016

Maximal Fat Oxidation is Related to Performance in an Ironman Triathlon

scientific article published on 19 October 2017

Maximal fat oxidation rates in endurance trained and untrained women

scientific article published on 28 September 2006

Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males

scientific article published on 27 August 2013

Menstrual cycle phase does not affect whole body peak fat oxidation rate during a graded exercise test

scientific article published on 20 February 2020

Metabolic profile in two physically active Inuit groups consuming either a western or a traditional Inuit diet.

scientific article

Metformin-treated patients with type 2 diabetes have normal mitochondrial complex I respiration

scientific article published on 19 October 2011

Mitochondrial adaptations to high intensity interval training in older females and males

scientific article published on 30 May 2019

Mitochondrial coupling and capacity of oxidative phosphorylation in skeletal muscle of Inuit and Caucasians in the arctic winter.

scientific article published on December 2015

Mitochondrial respiratory capacity remains stable despite a comprehensive and sustained increase in insulin sensitivity in obese patients undergoing gastric bypass surgery.

scientific article

Moving in extreme environments: extreme loading; carriage versus distance

scientific article

Muscle ceramide content in man is higher in type I than type II fibers and not influenced by glycogen content.

scientific article

Muscle ceramide content is similar after 3 weeks’ consumption of fat or carbohydrate diet in a crossover design in patients with type 2 diabetes

scientific article published on 22 June 2011

Muscle dysfunction during exercise of a single skeletal muscle in rats with congestive heart failure is not associated with reduced muscle blood supply

scientific article

Muscle metabolism during graded quadriceps exercise in man

scientific article published on 22 March 2007

Muscle mitochondrial capacity exceeds maximal oxygen delivery in humans

scientific article published on 13 December 2010

Muscle strength and physical activity are associated with self-rated health in an adult Danish population

scientific article published on 9 September 2013

Muscle triacylglycerol and hormone-sensitive lipase activity in untrained and trained human muscles

scientific article published on 10 June 2006

Muscle-Saturated Bioactive Lipids Are Increased with Aging and Influenced by High-Intensity Interval Training ⬇️

scientific article published on 12 March 2019

Normal mitochondrial function and increased fat oxidation capacity in leg and arm muscles in obese humans

scientific article published on 15 June 2010

Obesity leads to impairments in the morphology and organization of human skeletal muscle lipid droplets and mitochondrial networks, which are resolved with gastric bypass surgery-induced improvements in insulin sensitivity

scientific article published on 10 June 2018

Optimizing Maximal Fat Oxidation Assessment by a Treadmill-Based Graded Exercise Protocol: When Should the Test End?

scientific article published on 23 July 2019

Partial restoration of dietary fat induced metabolic adaptations to training by 7 days of carbohydrate diet.

scientific article published in November 2002

Peak Fat Oxidation is not Independently Related to Ironman Performance in Women

scientific article published on 18 September 2018

Plasma Free Fatty Acid concentration is closely tied to whole-body peak fat oxidation rate during repeated exercise

scientific article published on 07 March 2019

Positive effects of 1-year football and strength training on mechanical muscle function and functional capacity in elderly men.

scientific article

Preoperative β-cell function in patients with type 2 diabetes is important for the outcome of Roux-en-Y gastric bypass surgery

Prolonged adaptation to fat-rich diet and training; effects on body fat stores and insulin resistance in man

scientific article published on 01 August 2002

Repeated Excessive Exercise Attenuates the Anti-Inflammatory Effects of Exercise in Older Men.

scientific article

Repeated lifestyle interventions lead to progressive weight loss: A retrospective review chart study

scientific article

Repeated prolonged whole-body low-intensity exercise: effects on insulin sensitivity and limb muscle adaptations.

scientific article published in February 2006

Reply: To PMID 23287371

scientific article published on 18 April 2013

Reply: To PMID 23287371.

scientific article

Reproductive hormones and metabolic syndrome in 24 testicular cancer survivors and their biological brothers

scientific article

Sex hormone-binding globulin levels predict insulin sensitivity, disposition index, and cardiovascular risk during puberty.

scientific article published on 05 February 2009

Significant gender difference in serum levels of fibroblast growth factor 21 in Danish children and adolescents

scientific article published on 23 May 2014

Simvastatin effects on skeletal muscle: relation to decreased mitochondrial function and glucose intolerance.

scientific article published in January 2013

Simvastatin-Induced Insulin Resistance May Be Linked to Decreased Lipid Uptake and Lipid Synthesis in Human Skeletal Muscle: the LIFESTAT Study

scientific article published on 12 September 2018

Six weeks' aerobic retraining after two weeks' immobilization restores leg lean mass and aerobic capacity but does not fully rehabilitate leg strength in young and older men

scientific article published on 01 June 2015

Skeletal muscle mitochondrial H2 O2 emission increases with immobilization and decreases after aerobic training in young and older men.

scientific article published on 12 June 2015

Skeletal muscle mitochondrial respiration in AMPKα2 kinase-dead mice.

scientific article

Skiing across the Greenland icecap: divergent effects on limb muscle adaptations and substrate oxidation

scientific article published in March 2003

Statin treatment decreases mitochondrial respiration but muscle coenzyme Q10 levels are unaltered: The LIFESTAT study

scientific article published on 01 July 2019

Substrate availability and transcriptional regulation of metabolic genes in human skeletal muscle during recovery from exercise

scientific article published in August 2005

Temporary impact of blood donation on physical performance and hematologic variables in women.

scientific article published on 28 April 2017

The "Football is Medicine" platform-scientific evidence, large-scale implementation of evidence-based concepts and future perspectives

article

The Danish Health Examination Survey 2007-2008 (DANHES 2007-2008) ⬇️

scientific article published on January 21, 2011

The Effect of Reduced Physical Activity and Retraining on Blood Lipids and Body Composition in Young and Older Adult Men

scientific article published on 21 November 2014

The Influence of Age and Cardiorespiratory Fitness on Bioactive Lipids in Muscle

scientific article published on 01 May 2019

The association between physical activity, cardiorespiratory fitness and self-rated health.

scientific article published on 5 October 2013

The best approach: homogenization or manual permeabilization of human skeletal muscle fibers for respirometry?

scientific article published on 23 October 2013

The combination of cardiorespiratory fitness and muscle strength, and mortality risk.

scientific article published on 28 March 2018

The effect of age and unilateral leg immobilization for 2 weeks on substrate utilization during moderate-intensity exercise in human skeletal muscle

scientific article published on 23 January 2016

The effect of graded exercise on IL-6 release and glucose uptake in human skeletal muscle

scientific article

The effect of high-intensity training on mitochondrial fat oxidation in skeletal muscle and subcutaneous adipose tissue

scientific article published on 21 May 2014

The effect of metformin on glucose homeostasis during moderate exercise

scientific article published on 02 December 2014

The effects of 2 weeks of statin treatment on mitochondrial respiratory capacity in middle-aged males: the LIFESTAT study.

scientific article published on 28 February 2017

The effects of diet- and RYGB-induced weight loss on insulin sensitivity in obese patients with and without type 2 diabetes

scientific article published on 26 October 2015

The incretin effect does not differ in trained and untrained, young, healthy men

scientific article published on 16 January 2014

The influence of age and aerobic fitness: effects on mitochondrial respiration in skeletal muscle

scientific article published on 11 February 2012

Three-dimensional reconstruction of the human skeletal muscle mitochondrial network as a tool to assess mitochondrial content and structural organization

scientific article published on 15 April 2014

Time course for the recovery of physical performance, blood hemoglobin, and ferritin content after blood donation

scientific article published on 16 December 2014

Time trends in physical activity in leisure time in the Danish population from 1987 to 2005.

scientific article published on 11 January 2010

Total sitting time and risk of myocardial infarction, coronary heart disease and all-cause mortality in a prospective cohort of Danish adults

scientific article published on 05 February 2014

Training Does Not Alter Muscle Ceramide and Diacylglycerol in Offsprings of Type 2 Diabetic Patients Despite Improved Insulin Sensitivity

scientific article published on 29 September 2016

Training and natural immunity: effects of diets rich in fat or carbohydrate

scientific article published on 01 May 2000

Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice

scientific article

Two weeks of one-leg immobilization decreases skeletal muscle respiratory capacity equally in young and elderly men.

scientific article published on 2 September 2014

Validation of an Internet-based long version of the International Physical Activity Questionnaire in Danish adults using combined accelerometry and heart rate monitoring

scientific article published on 8 February 2013

Variation in mitochondrial respiratory capacity and myosin heavy chain composition in repeated muscle biopsies

scientific article published on 30 June 2018

Whole-body fat oxidation determined by graded exercise and indirect calorimetry: a role for muscle oxidative capacity?

scientific article published in June 2006

[Eating for top performance in sports?]

scientific article published on 01 December 2006

[Effect of lifestyle changes on weight loss and weight loss maintenance] ⬇️

[Metabolic capacity of skeletal muscles and health]

scientific article published on 01 April 2000

[Skeletal muscles, physical activity and health]

miRNAs in human subcutaneous adipose tissue: Effects of weight loss induced by hypocaloric diet and exercise.

scientific article published on 3 February 2017

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