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List of works by Karl Kuchler

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The pdr12 ABC transporter is required for the development of weak organic acid resistance in yeast

scientific article
Candida albicans cell surface superoxide dismutases degrade host-derived reactive oxygen species to escape innate immune surveillance.

scientific article published on 4 November 2008
Endoplasmic reticulum degradation of a mutated ATP-binding cassette transporter Pdr5 proceeds in a concerted action of Sec61 and the proteasome.

scientific article
Subcellular and submitochondrial localization of phospholipid-synthesizing enzymes in Saccharomyces cerevisiae.

scientific article
Global gene deletion analysis exploring yeast filamentous growth

scientific article published on 01 September 2012
Endocytosis and vacuolar degradation of the plasma membrane-localized Pdr5 ATP-binding cassette multidrug transporter in Saccharomyces cerevisiae.

scientific article published on November 1995
The facultative intracellular pathogen Candida glabrata subverts macrophage cytokine production and phagolysosome maturation

scientific article
Yeast ABC transporters-- a tale of sex, stress, drugs and aging.

scientific article
Global Phenotypic Analysis and Transcriptional Profiling Defines the Weak Acid Stress Response Regulon in Saccharomyces cerevisiae

scientific article published on November 14, 2003
Genetic separation of FK506 susceptibility and drug transport in the yeast Pdr5 ATP-binding cassette multidrug resistance transporter.

scientific article
Molecular cloning and expression of the Saccharomyces cerevisiae STS1 gene product. A yeast ABC transporter conferring mycotoxin resistance.

scientific article published in February 1994
Type I interferons promote fatal immunopathology by regulating inflammatory monocytes and neutrophils during Candida infections

scientific article
The Candida albicans Cdr2p ATP-binding cassette (ABC) transporter confers resistance to caspofungin.

scientific article
An Interspecies Regulatory Network Inferred from Simultaneous RNA-seq of Candida albicans Invading Innate Immune Cells

scientific article published on 12 March 2012
The a-factor transporter (STE6 gene product) and cell polarity in the yeast Saccharomyces cerevisiae

scientific article published on March 1, 1993
Systematic phenotyping of a large-scale Candida glabrata deletion collection reveals novel antifungal tolerance genes

scientific article (publication date: June 2014)
DENR-MCT-1 promotes translation re-initiation downstream of uORFs to control tissue growth

scientific article
Identification of mouse histone deacetylase 1 as a growth factor-inducible gene

scientific journal article
The yeast multidrug transporter Pdr5 of the plasma membrane is ubiquitinated prior to endocytosis and degradation in the vacuole

scientific article published on 01 January 1996
Conventional dendritic cells mount a type I IFN response against Candida spp. requiring novel phagosomal TLR7-mediated IFN-β signaling

scientific article published on 31 January 2011
War1p, a novel transcription factor controlling weak acid stress response in yeast.

scientific article
Plasma membrane translocation of fluorescent-labeled phosphatidylethanolamine is controlled by transcription regulators, PDR1 and PDR3

scientific article
Candida glabrata environmental stress response involves Saccharomyces cerevisiae Msn2/4 orthologous transcription factors

scientific article
The yeast ATP binding cassette (ABC) protein genes PDR10 and PDR15 are novel targets for the Pdr1 and Pdr3 transcriptional regulators

scientific article published on December 1, 1997
Fungal ABC proteins: pleiotropic drug resistance, stress response and cellular detoxification.

scientific article
The yeast zinc finger regulators Pdr1p and Pdr3p control pleiotropic drug resistance (PDR) as homo- and heterodimers in vivo

scientific article published on 01 December 2002
The Set3/Hos2 histone deacetylase complex attenuates cAMP/PKA signaling to regulate morphogenesis and virulence of Candida albicans

scientific article
Candida glabrata persistence in mice does not depend on host immunosuppression and is unaffected by fungal amino acid auxotrophy.

scientific article
Transcriptional loops meet chromatin: a dual-layer network controls white-opaque switching in Candida albicans

scientific article published on 23 June 2009
Reversal of antifungal resistance mediated by ABC efflux pumps from Candida albicans functionally expressed in yeast

scientific article published in September 2003
The ATP-binding cassette multidrug transporter Snq2 of Saccharomyces cerevisiae: a novel target for the transcription factors Pdr1 and Pdr3

scientific article published on 01 April 1996
The Saccharomyces cerevisiae weak-acid-inducible ABC transporter Pdr12 transports fluorescein and preservative anions from the cytosol by an energy-dependent mechanism

scientific article
Human Dermo-1 has attributes similar to twist in early bone development

scientific article
Functional expression of human mdr1 in the yeast Saccharomyces cerevisiae

scientific article published on March 1992
MAPK Hog1 closes the S. cerevisiae glycerol channel Fps1 by phosphorylating and displacing its positive regulators.

scientific article
Diazaborine resistance in the yeast Saccharomyces cerevisiae reveals a link between YAP1 and the pleiotropic drug resistance genes PDR1 and PDR3.

scientific article
Weak organic acid stress inhibits aromatic amino acid uptake by yeast, causing a strong influence of amino acid auxotrophies on the phenotypes of membrane transporter mutants

scientific article published in August 2003
Fungal attacks on mammalian hosts: pathogen elimination requires sensing and tasting.

scientific article published on 09 June 2010
A histone deacetylase adjusts transcription kinetics at coding sequences during Candida albicans morphogenesis

scientific article
Fungal pathogens-a sweet and sour treat for toll-like receptors

scientific article
The ATP-binding cassette (ABC) transporter Bpt1p mediates vacuolar sequestration of glutathione conjugates in yeast.

scientific article published in June 2002
The transmembrane domain 10 of the yeast Pdr5p ABC antifungal efflux pump determines both substrate specificity and inhibitor susceptibility

scientific article
Immune evasion, stress resistance, and efficient nutrient acquisition are crucial for intracellular survival of Candida glabrata within macrophages

scientific article published on 20 December 2013
Inhibition of CBLB protects from lethal Candida albicans sepsis

scientific article published on 18 July 2016
Yeast ATP-binding cassette transporters: cellular cleaning pumps.

scientific article
Moderately lipophilic carboxylate compounds are the selective inducers of the Saccharomyces cerevisiae Pdr12p ATP-binding cassette transporter.

scientific article published in May 2003
Secretion of peptides and proteins lacking hydrophobic signal sequences: the role of adenosine triphosphate-driven membrane translocators

scientific article published on August 1, 1992
Loss of peroxisome function triggers necrosis.

scientific article published on 24 July 2008
Expression regulation of the yeast PDR5 ATP-binding cassette (ABC) transporter suggests a role in cellular detoxification during the exponential growth phase

scientific article published in February 2004
A histone deacetylase complex mediates biofilm dispersal and drug resistance in Candida albicans.

scientific article

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