Search filters

List of works by Joseph E Deweese

A novel and unified two-metal mechanism for DNA cleavage by type II and IA topoisomerases

scientific article

Catalytic core of human topoisomerase IIα: insights into enzyme-DNA interactions and drug mechanism

scientific article

Clarifying the Mechanism of Copper(II) α-(N)-Heterocyclic Thiosemicarbazone Complexes on DNA Topoisomerase IIα and IIβ

scientific article published on 20 September 2019

Coordinating the two protomer active sites of human topoisomerase IIalpha: nicks as topoisomerase II poisons

scientific article published on February 2009

DNA cleavage and opening reactions of human topoisomerase IIα are regulated via Mg2+-mediated dynamic bending of gate-DNA

scientific article

Etoposide catechol is an oxidizable topoisomerase II poison

scientific article published on 23 July 2013

Etoposide quinone is a covalent poison of human topoisomerase IIβ.

scientific article published on 2 May 2014

Etoposide quinone is a redox-dependent topoisomerase II poison

scientific article

Examination of the Impact of Copper(II) α-(N)-Heterocyclic Thiosemicarbazone Complexes on DNA Topoisomerase IIα.

scientific article published on 16 March 2016

Examining the Impact of Antimicrobial Fluoroquinolones on Human DNA Topoisomerase IIα and IIβ

scientific article published on 22 February 2019

HU-331 and Oxidized Cannabidiol Act as Inhibitors of Human Topoisomerase IIα and β.

scientific article published on 22 December 2017

HU-331 is a catalytic inhibitor of topoisomerase IIα.

scientific article published on 3 December 2014

Structural and Metal Ion Effects on Human Topoisomerase IIα Inhibition by α-(N)-Heterocyclic Thiosemicarbazones

scientific article published on 11 December 2018

The DNA cleavage reaction of topoisomerase II: wolf in sheep's clothing

scientific article

The use of divalent metal ions by type II topoisomerases.

scientific article

Two-Mechanism Model for the Interaction of Etoposide Quinone with Topoisomerase IIα.

scientific article

Use of divalent metal ions in the dna cleavage reaction of human type II topoisomerases.

scientific article published on March 2009

Paulina is supported by:

About Paulina

Help