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List of works by Anastassios Economou

A Reporter System for Fast Quantitative Monitoring of Type 3 Protein Secretion in Enteropathogenic E. coli

scientific article published on 14 November 2020

A double point mutation at residues Ile14 and Val15 of Bcl-2 uncovers a role for the BH4 domain in both protein stability and function

scientific article published on 13 November 2017

A molecular switch in SecA protein couples ATP hydrolysis to protein translocation

scientific article published on 01 December 1999

Allosteric communication between signal peptides and the SecA protein DEAD motor ATPase domain.

scientific article

Analysis of Translocation-Competent Secretory Proteins by HDX-MS.

scientific article

Antibiotic targeting of the bacterial secretory pathway.

scientific article published on 15 February 2014

Assembly of the translocase motor onto the preprotein-conducting channel.

scientific article published on 22 August 2008

BDA-366, a putative Bcl-2 BH4 domain antagonist, induces apoptosis independently of Bcl-2 in a variety of cancer cell models

scientific article published on 17 September 2020

Bacterial preprotein translocase: mechanism and conformational dynamics of a processive enzyme.

scientific article published on February 1998

Bacterial protein translocase: a unique molecular machine with an army of substrates.

scientific article published in June 2000

Breaching the wall

scientific article published on 01 November 2018

Breaking on through to the other side: protein export through the bacterial Sec system.

scientific article published on January 2013

Cloning, purification and characterization of a functional anthracycline glycosyltransferase

scientific article

Comparative proteomic analysis of hypertrophic chondrocytes in osteoarthritis.

scientific article published on 25 April 2015

Complete genome sequence of Streptomyces lividans TK24.

scientific article published on 11 February 2015

Comprehensive subcellular topologies of polypeptides in Streptomyces.

scientific article published on 15 March 2018

Cross-talk between catalytic and regulatory elements in a DEAD motor domain is essential for SecA function

scientific article

Development of a high-throughput screening assay for the discovery of small-molecule SecA inhibitors

scientific article published on February 19, 2011

Disorder-order folding transitions underlie catalysis in the helicase motor of SecA

scientific article published on 18 June 2006

Double hexameric ring assembly of the type III protein translocase ATPase HrcN.

scientific article published on July 2006

Dynamics and ligand-induced conformational changes in human prolyl oligopeptidase analyzed by hydrogen/deuterium exchange mass spectrometry

scientific article published on 26 May 2017

Editorial: Thematic issue on bacterial protein export: from fundamentals to applications

scientific article published on 01 October 2018

Escherichia coli SecA shape and dimensions

scientific article published on 01 October 1998

Escherichia coli SecA truncated at its termini is functional and dimeric.

scientific article

Fast and reliable strain characterization of Streptomyces lividans through micro-scale cultivation.

scientific article

Following the leader: bacterial protein export through the Sec pathway.

scientific article

Functional large-scale production of a novel Jonesia sp. xyloglucanase by heterologous secretion from Streptomyces lividans.

scientific article

Global co-ordination of protein translocation by the SecA IRA1 switch

scientific article published on 7 March 2004

Helicase Motif III in SecA is essential for coupling preprotein binding to translocation ATPase.

scientific article

Hierarchical protein targeting and secretion is controlled by an affinity switch in the type III secretion system of enteropathogenic Escherichia coli.

scientific article published on 6 November 2017

Identification of small-molecule inhibitors against SecA by structure-based virtual ligand screening

scientific article

Identification of the preprotein binding domain of SecA.

scientific article published on 21 October 2005

In vitro assays to analyze translocation of the model secretory preprotein alkaline phosphatase.

scientific article published in January 2010

Large-scale production of a thermostable Rhodothermus marinus cellulase by heterologous secretion from Streptomyces lividans

scientific article

Long-Lived Folding Intermediates Predominate the Targeting-Competent Secretome

scientific article published on 05 April 2018

MatureP: prediction of secreted proteins with exclusive information from their mature regions.

scientific article published on 12 June 2017

Monitoring Protein Secretion in Using Fluorescent Proteins

scientific article published on 07 December 2018

Multi-Omics and Targeted Approaches to Determine the Role of Cellular Proteases in Streptomyces Protein Secretion.

scientific article

NS5A mutations predict biochemical but not virological response to interferon-alpha treatment of sporadic hepatitis C virus infection in European patients

scientific article published in July 2001

Optimization of type 3 protein secretion in enteropathogenic Escherichia coli

scholarly article by Biao Yuan et al published 24 May 2018 in FEMS Microbiology Letters

Preface for the special issue protein export/secretion in bacteria

article by R.E. Dalbey & Anastassios Economou published November 2004 in BBA: Molecular Cell Research

Preface to special issue on protein trafficking and secretion in bacteria

scientific article published on 13 April 2014

Preprotein Conformational Dynamics Drive Bivalent Translocase Docking and Secretion.

scientific article published on 5 June 2017

Preprotein mature domains contain translocase targeting signals that are essential for secretion

scientific article published on 12 April 2017

Preprotein-controlled catalysis in the helicase motor of SecA

scientific article

Protein Secretion in Gram-Positive Bacteria: From Multiple Pathways to Biotechnology

scientific article published on 25 November 2016

Protein Transport Across the Bacterial Plasma Membrane by the Sec Pathway

scientific article published on 01 June 2019

Protein export through the bacterial Sec pathway.

scientific article published on 28 November 2016

Protein folding in the cell envelope of Escherichia coli.

scientific article

Protein secretion biotechnology using Streptomyces lividans: large-scale production of functional trimeric tumor necrosis factor alpha

scientific article published in March 2001

Proteome Changes during Transition from Human Embryonic to Vascular Progenitor Cells

scientific article published on 5 May 2016

Proteome-wide subcellular topologies of E. coli polypeptides database (STEPdb).

scientific article

Purification of a functional mature region from a SecA-dependent preprotein

scientific article published on 01 April 2005

Quantitative Proteomics of the E. coli Membranome

scientific article

Quantitative analysis of energy transfer between fluorescent proteins in CFP-GBP-YFP and its response to Ca2+.

scientific article

Quaternary dynamics of the SecA motor drive translocase catalysis.

scientific article

Rapid label-free quantitative analysis of the E. coli BL21(DE3) inner membrane proteome

scientific article

Recognition and targeting mechanisms by chaperones in flagellum assembly and operation

scientific article published on 15 August 2016

Sec, drugs and rock’n’roll: antibiotic targeting of bacterial protein translocation

scientific article published on 01 April 2001

SecA membrane cycling at SecYEG is driven by distinct ATP binding and hydrolysis events and is regulated by SecD and SecF.

scientific article

SecA promotes preprotein translocation by undergoing ATP-driven cycles of membrane insertion and deinsertion

scientific article published in September 1994

SecA-mediated targeting and translocation of secretory proteins.

scientific article published on 25 February 2014

SecA: a tale of two protomers

scientific article published on 23 April 2010

SecYEG and SecA Are the Stoichiometric Components of Preprotein Translocase

scientific article published on August 25, 1995

Secretion of the Rhizobium leguminosarum nodulation protein NodO by haemolysin-type systems

scientific article published on 01 January 1992

Secretome Dynamics in a Gram-Positive Bacterial Model

scientific article published on 29 November 2018

Separable ATPase and Membrane Insertion Domains of the SecA Subunit of Preprotein Translocase

scientific article published in Journal of Biological Chemistry

Streptomyces protein secretion and its application in biotechnology

scientific article published on 01 November 2018

Structural Basis for Protein Antiaggregation Activity of the Trigger Factor Chaperone

scientific article

Structural Basis for Signal-Sequence Recognition by the Translocase Motor SecA as Determined by NMR

scientific article

Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases

scientific article published on 08 January 2020

Structural Instability Tuning as a Regulatory Mechanism in Protein-Protein Interactions

scientific article

Structural biology: Clamour for a kiss

scientific article

Structure of dimeric SecA, the Escherichia coli preprotein translocase motor

scientific article

Structures of chaperone-substrate complexes docked onto the export gate in a type III secretion system.

scientific article

The ATPase domain of SecA can form a tetramer in solution.

scientific article

The Escherichia coli peripheral inner membrane proteome

scientific article published on 10 December 2012

The P. CEZANNE Project: innovative approaches to continuous glucose Monitoring

scientific article published in January 2007

The Preprotein Binding Domain of SecA Displays Intrinsic Rotational Dynamics

scientific article published on 21 November 2018

The structural basis for an on-off switch controlling Gβγ-mediated inhibition of TRPM3 channels

scientific article published on 29 October 2020

Transcription of rhiA, a gene on a Rhizobium leguminosarum bv. viciae Sym plasmid, requires rhiR and is repressed by flavanoids that induce nod genes.

scientific article published in January 1989

Transcriptomic and fluxomic changes in Streptomyces lividans producing heterologous protein

scientific article published on 21 December 2018

Trigger factor is a bona fide secretory pathway chaperone that interacts with SecB and the translocase

scientific article published on 19 April 2020

Type III Secretion: Building and Operating a Remarkable Nanomachine.

scientific article

Type III protein translocase: HrcN is a peripheral ATPase that is activated by oligomerization

scientific article published on 6 May 2003

Using nanoelectrospray ion mobility spectrometry (GEMMA) to determine the size and relative molecular mass of proteins and protein assemblies: a comparison with MALLS and QELS.

scientific article

Xilmass: A New Approach toward the Identification of Cross-Linked Peptides

scientific article