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List of works by Geoffrey Masuyer

A neurotoxin that specifically targets Anopheles mosquitoes

scientific article published on 28 June 2019

Absence of cell surface expression of human ACE leads to perinatal death

scientific article published on 24 October 2013

Angiotensin-I converting enzyme (ACE): structure, biological roles, and molecular basis for chloride ion dependence

scientific article published on October 2014

Botulinum and Tetanus Neurotoxins

scientific article published on 02 November 2018

Characterization of a membrane binding loop leads to engineering botulinum neurotoxin B with improved therapeutic efficacy

scientific article published on 17 March 2020

Crystal Structure of Botulinum Neurotoxin A2 in Complex with the Human Protein Receptor SV2C Reveals Plasticity in Receptor Binding.

scientific article published on 12 April 2018

Crystal Structure of Exotoxin A from Aeromonas Pathogenic Species

scientific article published on 15 June 2020

Crystal structure of a catalytically active, non-toxic endopeptidase derivative of Clostridium botulinum toxin A

scientific article

Crystal structure of a peptidyl-dipeptidase K-26-DCP from Actinomycete in complex with its natural inhibitor

scientific article

Crystal structure of the catalytic domain of the Weissella oryzae botulinum-like toxin

scientific article published on 20 May 2019

Crystal structures of highly specific phosphinic tripeptide enantiomers in complex with the angiotensin-I converting enzyme

scientific article

Engineered botulinum neurotoxin B with improved binding to human receptors has enhanced efficacy in preclinical models

scientific article published on 16 January 2019

Engineered botulinum neurotoxins as new therapeutics

scientific article published on 30 August 2013

Engineering botulinum neurotoxin domains for activation by toxin light chain.

scientific article published on 23 December 2011

Fragment-based design for the development of N-domain-selective angiotensin-1-converting enzyme inhibitors

scientific article

Glycans Confer Specificity to the Recognition of Ganglioside Receptors by Botulinum Neurotoxin A.

scientific article

Identification and characterization of a novel botulinum neurotoxin.

scientific article published on 3 August 2017

Identification of a Botulinum Neurotoxin-like Toxin in a Commensal Strain of Enterococcus faecium.

scientific article published on 26 January 2018

Identification of a novel snake peptide toxin displaying high affinity and antagonist behaviour for the α2-adrenoceptors.

scientific article

Inhibition mechanism of human galectin-7 by a novel galactose-benzylphosphate inhibitor

scientific article

Interkingdom Pharmacology of Angiotensin-I Converting Enzyme Inhibitor Phosphonates Produced by Actinomycetes

scientific article

Isolation and pharmacological characterization of AdTx1, a natural peptide displaying specific insurmountable antagonism of the alpha1A-adrenoceptor.

scientific article

Kinetic and structural characterization of amyloid-β peptide hydrolysis by human angiotensin-1-converting enzyme.

scientific article published on 08 January 2016

Mechanism of Peptide Binding and Cleavage by the Human Mitochondrial Peptidase Neurolysin.

scientific article published on 25 November 2017

Molecular and Thermodynamic Mechanisms of the Chloride-dependent Human Angiotensin-I-converting Enzyme (ACE)

scientific article

Molecular recognition and regulation of human angiotensin-I converting enzyme (ACE) activity by natural inhibitory peptides ⬇️

scientific article published on October 9, 2012

NUDT15 Hydrolyzes 6-Thio-DeoxyGTP to Mediate the Anticancer Efficacy of 6-Thioguanine

scientific article

Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation

scientific article

Structural analysis of Clostridium botulinum neurotoxin type D as a platform for the development of targeted secretion inhibitors

scientific article published on September 2015

Structural and Biochemical Characterization of Botulinum Neurotoxin Subtype B2 Binding to Its Receptors

scientific article published on 17 September 2020

Structural basis for the interaction of the chaperone Cbp3 with newly synthesized cytochrome b during mitochondrial respiratory chain assembly

scientific article published on 19 September 2019

Structural basis of Ac-SDKP hydrolysis by Angiotensin-I converting enzyme

scientific article

Structural basis of multivalent galactose-based dendrimer recognition by human galectin-7

scientific article

Structural basis of peptide recognition by the angiotensin-1 converting enzyme homologue AnCE from Drosophila melanogaster

scientific article

Structural characterisation of the catalytic domain of botulinum neurotoxin X - high activity and unique substrate specificity.

scientific article published on 14 March 2018

Structural characterization of angiotensin I‐converting enzyme in complex with a selenium analogue of captopril ⬇️

scientific article published on September 8, 2011

Structure and activity of a functional derivative of Clostridium botulinum neurotoxin B

scientific article

Structure based drug design of angiotensin-I converting enzyme inhibitors.

scientific article published on January 2012

The structure of the tetanus toxin reveals pH-mediated domain dynamics

scientific article published on 23 June 2017

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