List of works - Kirstine Calloe

A Novel SCN5A Mutation in a Patient with Coexistence of Brugada Syndrome Traits and Ischaemic Heart Disease

scientific article published on 13 October 2009

A common single nucleotide polymorphism can exacerbate long-QT type 2 syndrome leading to sudden infant death.

scientific article

A dual potassium channel activator improves repolarization reserve and normalizes ventricular action potentials.

scientific article published on 19 March 2016

A novel KCND3 gain-of-function mutation associated with early-onset of persistent lone atrial fibrillation

scientific article published on 11 February 2013

A novel nonsense variant in Nav1.5 cofactor MOG1 eliminates its sodium current increasing effect and may increase the risk of arrhythmias

scientific article

A transient outward potassium current activator recapitulates the electrocardiographic manifestations of Brugada syndrome.

scientific article published on 10 December 2008

Accelerated inactivation of the L-type calcium current due to a mutation in CACNB2b underlies Brugada syndrome

scientific article published in May 2009

Activation, permeability, and inhibition of astrocytic and neuronal large pore (hemi)channels

scientific article

Characterization and mechanisms of action of novel NaV1.5 channel mutations associated with Brugada syndrome

scientific article published in February 2013

Characterizations of a loss-of-function mutation in the Kir3.4 channel subunit.

scientific article

Comparison of the effects of a transient outward potassium channel activator on currents recorded from atrial and ventricular cardiomyocytes

scientific article

Compounds commonly used in equine medicine inhibits the voltage-gated potassium channel Kv11.1.

scientific article published on 08 January 2019

Corrigendum to “Molecular cloning and functional expression of the K + channel K V 7.1 and the regulatory subunit KCNE1 from equine myocardium” [Res. Vet. Sci. 113 (2017) 79–86]

scientific article published on 21 March 2018

Development of heart failure is independent of K+ channel-interacting protein 2 expression

scientific article published on 7 October 2013

Diet-induced pre-diabetes slows cardiac conductance and promotes arrhythmogenesis

scientific article published on 14 July 2015

Differential effects of the transient outward K(+) current activator NS5806 in the canine left ventricle

scientific article

Doctoral Dissertation: The transient outward potassium current in healthy and diseased hearts

scientific article published on 01 January 2019

Dysfunction of the Heteromeric KV7.3/KV7.5 Potassium Channel is Associated with Autism Spectrum Disorders

scientific article published on 16 April 2013

Effect of the I(to) activator NS5806 on cloned K(V)4 channels depends on the accessory protein KChIP2.

scientific article

Effects of trimethoprim-sulfadiazine and detomidine on the function of equine Kv 11.1 channels in a two-electrode voltage-clamp (TEVC) oocyte model

scientific article published on 22 March 2018

Functional assessment of compound mutations in the KCNQ1 and KCNH2 genes associated with long QT syndrome

scientific article published in November 2005

Functional properties of human neuronal Kv11 channels

scientific article published on 25 March 2009

Gliadin fragments and a specific gliadin 33-mer peptide close KATP channels and induce insulin secretion in INS-1E cells and rat islets of langerhans

scientific article (publication date: 2013)

Heteromeric Slick/Slack K+ channels show graded sensitivity to cell volume changes

scientific article

High incidence of functional ion-channel abnormalities in a consecutive Long QT cohort with novel missense genetic variants of unknown significance

scientific article

Human Embryonic Stem Cell-Derived Cardiomyocytes Self-Arrange with Areas of Different Subtypes During Differentiation.

scientific article published on 10 August 2017

Human atrial fibroblasts and their contribution to supraventricular arrhythmia

scientific article published on February 2016

Hypoosmotic cell swelling as a novel mechanism for modulation of cloned HCN2 channels

scientific article

Impact of KChIP2 on Cardiac Electrophysiology and the Progression of Heart Failure

scientific article

Interventricular differences in sodium current and its potential role in Brugada syndrome

KCNQ channels are involved in the regulatory volume decrease response in primary neonatal rat cardiomyocytes.

scientific article

Loss of K+ currents in heart failure is accentuated in KChIP2 deficient mice

scientific article published on 2 May 2014

Managing the complexity of communication: regulation of gap junctions by post-translational modification

scientific article published on 22 October 2013

Modulation of ERG channels by XE991.

scientific article published on May 2007

Molecular Cloning and Functional Expression of the Equine K+ Channel KV11.1 (Ether à Go-Go-Related/KCNH2 Gene) and the Regulatory Subunit KCNE2 from Equine Myocardium

scientific article

Molecular cloning and functional expression of the K+ channel KV7.1 and the regulatory subunit KCNE1 from equine myocardium.

scientific article

Multifocal atrial and ventricular premature contractions with an increased risk of dilated cardiomyopathy caused by a Na v 1.5 gain-of-function mutation (G213D)

scientific article published on 01 April 2018

Multiple arrhythmic syndromes in a newborn, owing to a novel mutation in SCN5A

scientific article

NS5806 partially restores action potential duration but fails to ameliorate calcium transient dysfunction in a computational model of canine heart failure.

scientific article published in November 2014

Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B

scientific article published on 06 February 2017

Physiological consequences of transient outward K+ current activation during heart failure in the canine left ventricle.

scientific article

Physiological roles of the transient outward current Ito in normal and diseased hearts

scientific article published on January 2016

Preservation of cardiac function by prolonged action potentials in mice deficient of KChIP2

scientific article published on 08 June 2015

Quantitative proteome comparison of human hearts with those of model organisms

scientific article published on 19 April 2021

Reconstitution and Electrophysiological Characterization of Ion Channels in Lipid Bilayers

scientific article published on 04 May 2018

Structure of the human ClC-1 chloride channel

scientific article published on 25 April 2019

The G213D variant in Nav1.5 alters sodium current and causes an arrhythmogenic phenotype resulting in a multifocal ectopic Purkinje-related premature contraction phenotype in human-induced pluripotent stem cell-derived cardiomyocytes

scientific article published in 2022

The Mutation P.T613a in the Pore Helix of the Kv 11.1 Potassium Channel is Associated with Long QT Syndrome.

scientific article

The acrylamide (S)-1 differentially affects Kv7 (KCNQ) potassium channels

scientific article published on 10 August 2006

The novel C-terminal KCNQ1 mutation M520R alters protein trafficking.

scientific article published on 27 April 2007

The small molecule NS11021 is a potent and specific activator of Ca2+-activated big-conductance K+ channels

scientific article

Tissue-specific effects of acetylcholine in the canine heart.

scientific article published on 03 May 2013

Ventricular repolarization time, location of pacing stimulus and current pulse amplitude conspire to determine arrhythmogenicity in mice.

scientific article published on 26 July 2016

List of works by Kirstine Calloe

A Novel SCN5A Mutation in a Patient with Coexistence of Brugada Syndrome Traits and Ischaemic Heart Disease

A common single nucleotide polymorphism can exacerbate long-QT type 2 syndrome leading to sudden infant death.

A dual potassium channel activator improves repolarization reserve and normalizes ventricular action potentials.

A novel KCND3 gain-of-function mutation associated with early-onset of persistent lone atrial fibrillation

A novel nonsense variant in Nav1.5 cofactor MOG1 eliminates its sodium current increasing effect and may increase the risk of arrhythmias

A transient outward potassium current activator recapitulates the electrocardiographic manifestations of Brugada syndrome.

Accelerated inactivation of the L-type calcium current due to a mutation in CACNB2b underlies Brugada syndrome

Activation, permeability, and inhibition of astrocytic and neuronal large pore (hemi)channels

Characterization and mechanisms of action of novel NaV1.5 channel mutations associated with Brugada syndrome

Characterizations of a loss-of-function mutation in the Kir3.4 channel subunit.

Comparison of the effects of a transient outward potassium channel activator on currents recorded from atrial and ventricular cardiomyocytes

Compounds commonly used in equine medicine inhibits the voltage-gated potassium channel Kv11.1.

Corrigendum to “Molecular cloning and functional expression of the K + channel K V 7.1 and the regulatory subunit KCNE1 from equine myocardium” [Res. Vet. Sci. 113 (2017) 79–86]

Development of heart failure is independent of K+ channel-interacting protein 2 expression

Diet-induced pre-diabetes slows cardiac conductance and promotes arrhythmogenesis

Differential effects of the transient outward K(+) current activator NS5806 in the canine left ventricle

Doctoral Dissertation: The transient outward potassium current in healthy and diseased hearts

Dysfunction of the Heteromeric KV7.3/KV7.5 Potassium Channel is Associated with Autism Spectrum Disorders

Effect of the I(to) activator NS5806 on cloned K(V)4 channels depends on the accessory protein KChIP2.

Effects of trimethoprim-sulfadiazine and detomidine on the function of equine Kv 11.1 channels in a two-electrode voltage-clamp (TEVC) oocyte model

Functional assessment of compound mutations in the KCNQ1 and KCNH2 genes associated with long QT syndrome

Functional properties of human neuronal Kv11 channels

Gliadin fragments and a specific gliadin 33-mer peptide close KATP channels and induce insulin secretion in INS-1E cells and rat islets of langerhans

Heteromeric Slick/Slack K+ channels show graded sensitivity to cell volume changes

High incidence of functional ion-channel abnormalities in a consecutive Long QT cohort with novel missense genetic variants of unknown significance

Human Embryonic Stem Cell-Derived Cardiomyocytes Self-Arrange with Areas of Different Subtypes During Differentiation.

Human atrial fibroblasts and their contribution to supraventricular arrhythmia

Hypoosmotic cell swelling as a novel mechanism for modulation of cloned HCN2 channels

Impact of KChIP2 on Cardiac Electrophysiology and the Progression of Heart Failure

Interventricular differences in sodium current and its potential role in Brugada syndrome

KCNQ channels are involved in the regulatory volume decrease response in primary neonatal rat cardiomyocytes.

Loss of K+ currents in heart failure is accentuated in KChIP2 deficient mice

Managing the complexity of communication: regulation of gap junctions by post-translational modification

Modulation of ERG channels by XE991.

Molecular Cloning and Functional Expression of the Equine K+ Channel KV11.1 (Ether à Go-Go-Related/KCNH2 Gene) and the Regulatory Subunit KCNE2 from Equine Myocardium

Molecular cloning and functional expression of the K+ channel KV7.1 and the regulatory subunit KCNE1 from equine myocardium.

Multifocal atrial and ventricular premature contractions with an increased risk of dilated cardiomyopathy caused by a Na v 1.5 gain-of-function mutation (G213D)

Multiple arrhythmic syndromes in a newborn, owing to a novel mutation in SCN5A

NS5806 partially restores action potential duration but fails to ameliorate calcium transient dysfunction in a computational model of canine heart failure.

Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B

Physiological consequences of transient outward K+ current activation during heart failure in the canine left ventricle.

Physiological roles of the transient outward current Ito in normal and diseased hearts

Preservation of cardiac function by prolonged action potentials in mice deficient of KChIP2

Quantitative proteome comparison of human hearts with those of model organisms

Reconstitution and Electrophysiological Characterization of Ion Channels in Lipid Bilayers

Structure of the human ClC-1 chloride channel

The G213D variant in Nav1.5 alters sodium current and causes an arrhythmogenic phenotype resulting in a multifocal ectopic Purkinje-related premature contraction phenotype in human-induced pluripotent stem cell-derived cardiomyocytes

The Mutation P.T613a in the Pore Helix of the Kv 11.1 Potassium Channel is Associated with Long QT Syndrome.

The acrylamide (S)-1 differentially affects Kv7 (KCNQ) potassium channels

The novel C-terminal KCNQ1 mutation M520R alters protein trafficking.

The small molecule NS11021 is a potent and specific activator of Ca2+-activated big-conductance K+ channels

Tissue-specific effects of acetylcholine in the canine heart.

Ventricular repolarization time, location of pacing stimulus and current pulse amplitude conspire to determine arrhythmogenicity in mice.