List of works - Tilman Grune

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Role of advanced glycation end products in cellular signaling

scientific article

Degradation of oxidized proteins in mammalian cells.

scientific article

Decreased proteolysis caused by protein aggregates, inclusion bodies, plaques, lipofuscin, ceroid, and 'aggresomes' during oxidative stress, aging, and disease.

scientific article published in December 2004

Proteolysis in cultured liver epithelial cells during oxidative stress. Role of the multicatalytic proteinase complex, proteasome.

scientific article published on February 1995

Ubiquitin conjugation is not required for the degradation of oxidized proteins by proteasome.

scientific article

Comparative resistance of the 20S and 26S proteasome to oxidative stress.

scientific article published on November 1998

Advanced glycation end products and oxidative stress in type 2 diabetes mellitus

scientific article

The proteasomal system.

scientific article published on 14 April 2009

Selective degradation of oxidatively modified protein substrates by the proteasome.

scientific article

Pathological aspects of lipid peroxidation.

scientific article

Degradation of oxidized proteins in K562 human hematopoietic cells by proteasome.

scientific article published on June 1996

Proteasome inhibition by paired helical filament-tau in brains of patients with Alzheimer's disease

scientific article published in April 2003

The immunoproteasome, the 20S proteasome and the PA28αβ proteasome regulator are oxidative-stress-adaptive proteolytic complexes.

scientific article published on December 2010

Poly-ADP ribose polymerase activates nuclear proteasome to degrade oxidatively damaged histones

scientific article published on May 1999

Peroxynitrite increases the degradation of aconitase and other cellular proteins by proteasome

scientific article

Clinical Relevance of Biomarkers of Oxidative Stress

scientific article

Immunoproteasome and LMP2 polymorphism in aged and Alzheimer's disease brains

scientific article

Protein oxidation in aging and the removal of oxidized proteins.

scientific article

HSP70 mediates dissociation and reassociation of the 26S proteasome during adaptation to oxidative stress.

scientific article published on 24 June 2011

Lipofuscin: formation, effects and role of macroautophagy

scientific article published on 19 January 2013

Proteasome-dependent degradation of oxidized proteins in MRC-5 fibroblasts

scientific article

Protein oxidation and 20S proteasome-dependent proteolysis in mammalian cells

scientific article published on September 1, 2001

Differential impairment of 20S and 26S proteasome activities in human hematopoietic K562 cells during oxidative stress

scientific article published on 01 May 2000

Beta-carotene is an important vitamin A source for humans

scientific article

The proteasomal system and HNE-modified proteins.

scientific article

Protein damage, repair and proteolysis.

scientific article published on 26 October 2012

Oxygen causes cell death in the developing brain

scientific article published on 01 November 2004

Oxidative stress, aging and the proteasomal system

scientific article published on January 1, 2000

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).

scientific article published on 18 May 2017

4-Hydroxynonenal-modified amyloid-beta peptide inhibits the proteasome: possible importance in Alzheimer's disease

scientific article

Age-associated analysis of oxidative stress parameters in human plasma and erythrocytes

scientific article published on 01 May 2006

Age-related changes in protein oxidation and proteolysis in mammalian cells.

scientific article

The proteasome and the degradation of oxidized proteins: part III-Redox regulation of the proteasomal system

scientific article published on 14 January 2014

Iron oxide particles for molecular magnetic resonance imaging cause transient oxidative stress in rat macrophages.

scientific article published in April 2004

Happily (n)ever after: Aging in the context of oxidative stress, proteostasis loss and cellular senescence

scientific article published on 07 December 2016

The proteasome and the degradation of oxidized proteins: Part II - protein oxidation and proteasomal degradation

scientific article

MARK-AGE biomarkers of ageing

scientific article

Proteasomal defense of oxidative protein modifications.

scientific article

Molecular effects of advanced glycation end products on cell signalling pathways, ageing and pathophysiology.

scientific article published on August 2013

Protein oxidation and degradation during postmitotic senescence.

scientific article published on November 2005

A diet rich in olive oil phenolics reduces oxidative stress in the heart of SAMP8 mice by induction of Nrf2-dependent gene expression.

scientific article published on 11 January 2012

Lipofuscin is formed independently of macroautophagy and lysosomal activity in stress-induced prematurely senescent human fibroblasts

scientific journal article

Protein oxidation and degradation during cellular senescence of human BJ fibroblasts: part II—aging of nondividing cells

scientific article published on 01 December 2000

Lipofuscin-bound iron is a major intracellular source of oxidants: role in senescent cells

scientific article published on 29 January 2010

Determination of protein carbonyls in plasma, cell extracts, tissue homogenates, isolated proteins: Focus on sample preparation and derivatization conditions

scientific article published on June 18, 2015

Pathophysiological importance of aggregated damaged proteins.

scientific article published on 12 March 2014

Oxidized proteins as a marker of oxidative stress during coronary heart surgery

scientific article published in November 1999

Molecular strategies to prevent, inhibit, and degrade advanced glycoxidation and advanced lipoxidation end products.

scientific article published on 07 May 2013

Lipofuscin accumulation in proliferating fibroblasts in vitro: an indicator of oxidative stress.

scientific article published on March 2001

List of works by Tilman Grune

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Role of advanced glycation end products in cellular signaling

Degradation of oxidized proteins in mammalian cells.

Decreased proteolysis caused by protein aggregates, inclusion bodies, plaques, lipofuscin, ceroid, and 'aggresomes' during oxidative stress, aging, and disease.

Proteolysis in cultured liver epithelial cells during oxidative stress. Role of the multicatalytic proteinase complex, proteasome.

Ubiquitin conjugation is not required for the degradation of oxidized proteins by proteasome.

Comparative resistance of the 20S and 26S proteasome to oxidative stress.

Advanced glycation end products and oxidative stress in type 2 diabetes mellitus

The proteasomal system.

Selective degradation of oxidatively modified protein substrates by the proteasome.

Pathological aspects of lipid peroxidation.

Degradation of oxidized proteins in K562 human hematopoietic cells by proteasome.

Proteasome inhibition by paired helical filament-tau in brains of patients with Alzheimer's disease

The immunoproteasome, the 20S proteasome and the PA28αβ proteasome regulator are oxidative-stress-adaptive proteolytic complexes.

Poly-ADP ribose polymerase activates nuclear proteasome to degrade oxidatively damaged histones

Peroxynitrite increases the degradation of aconitase and other cellular proteins by proteasome

Clinical Relevance of Biomarkers of Oxidative Stress

Immunoproteasome and LMP2 polymorphism in aged and Alzheimer's disease brains

Protein oxidation in aging and the removal of oxidized proteins.

HSP70 mediates dissociation and reassociation of the 26S proteasome during adaptation to oxidative stress.

Lipofuscin: formation, effects and role of macroautophagy

Proteasome-dependent degradation of oxidized proteins in MRC-5 fibroblasts

Protein oxidation and 20S proteasome-dependent proteolysis in mammalian cells

Differential impairment of 20S and 26S proteasome activities in human hematopoietic K562 cells during oxidative stress

Beta-carotene is an important vitamin A source for humans

The proteasomal system and HNE-modified proteins.

Protein damage, repair and proteolysis.

Oxygen causes cell death in the developing brain

Oxidative stress, aging and the proteasomal system

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).

4-Hydroxynonenal-modified amyloid-beta peptide inhibits the proteasome: possible importance in Alzheimer's disease

Age-associated analysis of oxidative stress parameters in human plasma and erythrocytes

Age-related changes in protein oxidation and proteolysis in mammalian cells.

The proteasome and the degradation of oxidized proteins: part III-Redox regulation of the proteasomal system

Iron oxide particles for molecular magnetic resonance imaging cause transient oxidative stress in rat macrophages.

Happily (n)ever after: Aging in the context of oxidative stress, proteostasis loss and cellular senescence

The proteasome and the degradation of oxidized proteins: Part II - protein oxidation and proteasomal degradation

MARK-AGE biomarkers of ageing

Proteasomal defense of oxidative protein modifications.

Molecular effects of advanced glycation end products on cell signalling pathways, ageing and pathophysiology.

Protein oxidation and degradation during postmitotic senescence.

A diet rich in olive oil phenolics reduces oxidative stress in the heart of SAMP8 mice by induction of Nrf2-dependent gene expression.

Lipofuscin is formed independently of macroautophagy and lysosomal activity in stress-induced prematurely senescent human fibroblasts

Protein oxidation and degradation during cellular senescence of human BJ fibroblasts: part II—aging of nondividing cells

Lipofuscin-bound iron is a major intracellular source of oxidants: role in senescent cells

Determination of protein carbonyls in plasma, cell extracts, tissue homogenates, isolated proteins: Focus on sample preparation and derivatization conditions

Pathophysiological importance of aggregated damaged proteins.

Oxidized proteins as a marker of oxidative stress during coronary heart surgery

Molecular strategies to prevent, inhibit, and degrade advanced glycoxidation and advanced lipoxidation end products.

Lipofuscin accumulation in proliferating fibroblasts in vitro: an indicator of oxidative stress.