List of works - Michael J. Kelso

5′-Substituted Amiloride Derivatives as Allosteric Modulators Binding in the Sodium Ion Pocket of the Adenosine A2A Receptor

scientific article published on 10 May 2016

6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer

scientific article published on 07 September 2018

A Cyclic Metallopeptide Induces α Helicity in Short Peptide Fragments of Thermolysin

scientific article published on 01 January 2003

A comparison of patient matched meibum and tear lipidomes.

scientific article published on 11 November 2013

A mass spectrometric investigation of novel quadruplex DNA-selective berberine derivatives

scientific article published on 16 August 2010

Anti-malarial effect of histone deacetylation inhibitors and mammalian tumour cytodifferentiating agents

scientific article published in May 2000

Anti-tumour/metastasis effects of the potassium-sparing diuretic amiloride: an orally active anti-cancer drug waiting for its call-of-duty?

scientific article

Attaching NorA efflux pump inhibitors to methylene blue enhances antimicrobial photodynamic inactivation of Escherichia coli and Acinetobacter baumannii in vitro and in vivo.

scientific article published on 24 February 2018

Attaching the NorA Efflux Pump Inhibitor INF55 to Methylene Blue Enhances Antimicrobial Photodynamic Inactivation of Methicillin-Resistant Staphylococcus aureus in Vitro and in Vivo

scientific article published on 11 August 2017

Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs

scientific article

Berberine-INF55 (5-nitro-2-phenylindole) hybrid antimicrobials: effects of varying the relative orientation of the berberine and INF55 components

scientific article published on 24 May 2010

Catalytic enantioselective conjugate addition of carbamates

scientific article published on 01 August 2004

Cephalosporin-3'-Diazeniumdiolate NO Donor Prodrug PYRRO-C3D Enhances Azithromycin Susceptibility of Nontypeable Haemophilus influenzae Biofilms.

scientific article published on 05 December 2016

Cephalosporin-3′-diazeniumdiolates: Targeted NO-Donor Prodrugs for Dispersing Bacterial Biofilms

article

Cephalosporin-NO-donor prodrug PYRRO-C3D shows β-lactam-mediated activity against Streptococcus pneumoniae biofilms.

scientific article published on 21 February 2017

Characterization of Five Novel Anti-MRSA Compounds Identified Using a Whole-Animal Caenorhabditis elegans/Galleria mellonella Sequential-Screening Approach

scientific article published on 27 July 2020

Clostridium difficile infection: molecular pathogenesis and novel therapeutics

scientific article

Conformationally constrained macrocycles that mimic tripeptide beta-strands in water and aprotic solvents

scientific article

Corrigendum to "Crystal structures and biochemical characterization of DNA sliding clamps from three Gram-negative bacterial pathogens" [J. Struct. Biol. 204 (3) (2018) 396-405]

scientific article published on 13 May 2019

Crystal structures and biochemical characterization of DNA sliding clamps from three Gram-negative bacterial pathogens

scientific article published on 23 October 2018

DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs

scientific article

Determination of ester position in isomeric (O-acyl)-hydroxy fatty acids by ion trap mass spectrometry.

scientific article published on 12 August 2016

Diarylacylhydrazones: Clostridium-selective antibacterials with activity against stationary-phase cells

scientific article published on 10 December 2013

Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach

scientific article

Introduction of a Fixed-Charge, Photolabile Derivative for Enhanced Structural Elucidation of Fatty Acids

scientific article published on 25 July 2019

Linkage isomerism in the binding of pentapeptide Ac-His(Ala)3His-NH2 to (ethylenediamine)palladium(II): effect of the binding mode on peptide conformation

scientific article

Low-Dose Nitric Oxide as Targeted Anti-biofilm Adjunctive Therapy to Treat Chronic Pseudomonas aeruginosa Infection in Cystic Fibrosis

scientific article

Mass spectrometry-directed structure elucidation and total synthesis of ultra-long chain (-acyl)-ω-hydroxy fatty acids

scientific article published on 15 June 2018

Novel cylindrical, conical, and macrocyclic peptides from the cyclooligomerization of functionalized thiazole amino acids

scientific article published in January 2001

On the stability of a single-turn alpha-helix: the single versus multiconformation problem

scientific article published in January 2003

Primary ciliary dyskinesia ciliated airway cells show increased susceptibility to Haemophilus influenzae biofilm formation

scientific article

Propyl-5-hydroxy-3-methyl-1-phenyl-1H-pyrazole-4-carbodithioate (HMPC): a new bacteriostatic agent against methicillin-resistant Staphylococcus aureus.

scientific article published on 4 May 2018

Prototyping kinase inhibitor-cytotoxin anticancer mutual prodrugs activated by tumour hypoxia: A chemical proof of concept study

scientific article published on 13 March 2019

Roles of the Na+/H+ Exchanger Isoform 1 and Urokinase in Prostate Cancer Cell Migration and Invasion

scientific article published on 10 December 2021

Small molecule antagonists of the urokinase (uPA): urokinase receptor (uPAR) interaction with high reported potencies show only weak effects in cell-based competition assays employing the native uPAR ligand.

scientific article published on 12 March 2011

Strategies to potentiate antimicrobial photoinactivation by overcoming resistant phenotypes

scientific article

Structural and thermodynamic dissection of linear motif recognition by the E. coli sliding clamp

scientific article

Structure-activity relationships of 2-aryl-1H-indole inhibitors of the NorA efflux pump in Staphylococcus aureus.

scientific article published on 2 July 2008

Structure-activity relationships of alpha-ketooxazole inhibitors of fatty acid amide hydrolase

scientific article published on 9 June 2007

Synthesis and preliminary evaluation of 5,7-dimethyl-2-aryl-3H-pyrrolizin-3-ones as angiogenesis inhibitors

scientific article

Synthesis and preliminary evaluation of amiloride analogs as inhibitors of the urokinase-type plasminogen activator (uPA)

scientific article published in November 2011

Synthesis of Berberine-Efflux Pump Inhibitor Hybrid Antibacterials.

scientific article published on January 2010

Synthesis of cephalosporin-3'-diazeniumdiolates: biofilm dispersing NO-donor prodrugs activated by β-lactamase

scientific article published in May 2013

Virulence profile: Mike Kelso

scientific article published on 21 September 2017

List of works by Michael J. Kelso

5′-Substituted Amiloride Derivatives as Allosteric Modulators Binding in the Sodium Ion Pocket of the Adenosine A2A Receptor

6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer

A Cyclic Metallopeptide Induces α Helicity in Short Peptide Fragments of Thermolysin

A comparison of patient matched meibum and tear lipidomes.

A mass spectrometric investigation of novel quadruplex DNA-selective berberine derivatives

Anti-malarial effect of histone deacetylation inhibitors and mammalian tumour cytodifferentiating agents

Anti-tumour/metastasis effects of the potassium-sparing diuretic amiloride: an orally active anti-cancer drug waiting for its call-of-duty?

Attaching NorA efflux pump inhibitors to methylene blue enhances antimicrobial photodynamic inactivation of Escherichia coli and Acinetobacter baumannii in vitro and in vivo.

Attaching the NorA Efflux Pump Inhibitor INF55 to Methylene Blue Enhances Antimicrobial Photodynamic Inactivation of Methicillin-Resistant Staphylococcus aureus in Vitro and in Vivo

Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs

Berberine-INF55 (5-nitro-2-phenylindole) hybrid antimicrobials: effects of varying the relative orientation of the berberine and INF55 components

Catalytic enantioselective conjugate addition of carbamates

Cephalosporin-3'-Diazeniumdiolate NO Donor Prodrug PYRRO-C3D Enhances Azithromycin Susceptibility of Nontypeable Haemophilus influenzae Biofilms.

Cephalosporin-3′-diazeniumdiolates: Targeted NO-Donor Prodrugs for Dispersing Bacterial Biofilms

Cephalosporin-NO-donor prodrug PYRRO-C3D shows β-lactam-mediated activity against Streptococcus pneumoniae biofilms.

Characterization of Five Novel Anti-MRSA Compounds Identified Using a Whole-Animal Caenorhabditis elegans/Galleria mellonella Sequential-Screening Approach

Clostridium difficile infection: molecular pathogenesis and novel therapeutics

Conformationally constrained macrocycles that mimic tripeptide beta-strands in water and aprotic solvents

Corrigendum to "Crystal structures and biochemical characterization of DNA sliding clamps from three Gram-negative bacterial pathogens" [J. Struct. Biol. 204 (3) (2018) 396-405]

Crystal structures and biochemical characterization of DNA sliding clamps from three Gram-negative bacterial pathogens

DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs

Determination of ester position in isomeric (O-acyl)-hydroxy fatty acids by ion trap mass spectrometry.

Diarylacylhydrazones: Clostridium-selective antibacterials with activity against stationary-phase cells

Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach

Introduction of a Fixed-Charge, Photolabile Derivative for Enhanced Structural Elucidation of Fatty Acids

Linkage isomerism in the binding of pentapeptide Ac-His(Ala)3His-NH2 to (ethylenediamine)palladium(II): effect of the binding mode on peptide conformation

Low-Dose Nitric Oxide as Targeted Anti-biofilm Adjunctive Therapy to Treat Chronic Pseudomonas aeruginosa Infection in Cystic Fibrosis

Mass spectrometry-directed structure elucidation and total synthesis of ultra-long chain (-acyl)-ω-hydroxy fatty acids

Novel cylindrical, conical, and macrocyclic peptides from the cyclooligomerization of functionalized thiazole amino acids

On the stability of a single-turn alpha-helix: the single versus multiconformation problem

Primary ciliary dyskinesia ciliated airway cells show increased susceptibility to Haemophilus influenzae biofilm formation

Propyl-5-hydroxy-3-methyl-1-phenyl-1H-pyrazole-4-carbodithioate (HMPC): a new bacteriostatic agent against methicillin-resistant Staphylococcus aureus.

Prototyping kinase inhibitor-cytotoxin anticancer mutual prodrugs activated by tumour hypoxia: A chemical proof of concept study

Roles of the Na+/H+ Exchanger Isoform 1 and Urokinase in Prostate Cancer Cell Migration and Invasion

Small molecule antagonists of the urokinase (uPA): urokinase receptor (uPAR) interaction with high reported potencies show only weak effects in cell-based competition assays employing the native uPAR ligand.

Strategies to potentiate antimicrobial photoinactivation by overcoming resistant phenotypes

Structural and thermodynamic dissection of linear motif recognition by the E. coli sliding clamp

Structure-activity relationships of 2-aryl-1H-indole inhibitors of the NorA efflux pump in Staphylococcus aureus.

Structure-activity relationships of alpha-ketooxazole inhibitors of fatty acid amide hydrolase

Synthesis and preliminary evaluation of 5,7-dimethyl-2-aryl-3H-pyrrolizin-3-ones as angiogenesis inhibitors

Synthesis and preliminary evaluation of amiloride analogs as inhibitors of the urokinase-type plasminogen activator (uPA)

Synthesis of Berberine-Efflux Pump Inhibitor Hybrid Antibacterials.

Synthesis of cephalosporin-3'-diazeniumdiolates: biofilm dispersing NO-donor prodrugs activated by β-lactamase

Virulence profile: Mike Kelso