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List of works by Zsofia Kote-Jarai

A Cross-Cancer Genetic Association Analysis of the DNA Repair and DNA Damage Signaling Pathways for Lung, Ovary, Prostate, Breast, and Colorectal Cancer

scientific article

A Germline Variant at 8q24 Contributes to Familial Clustering of Prostate Cancer in Men of African Ancestry

scientific article published on 11 May 2020

A Large-Scale Analysis of Genetic Variants within Putative miRNA Binding Sites in Prostate Cancer

scientific article

A genetic risk score to guide age-specific, personalized prostate cancer screening

A genetic risk score to personalize prostate cancer screening, applied to population data

scientific article published on 24 June 2020

A genetic study and meta-analysis of the genetic predisposition of prostate cancer in a Chinese population

scientific article published on 08 February 2016

A genome-wide association scan (GWAS) for mean telomere length within the COGS project: identified loci show little association with hormone-related cancer risk

scientific article published on 29 July 2013

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

scientific article published on June 2016

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

scientific article published on 14 September 2014

A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease

scientific article

A multicopy dinucleotide marker that maps close to the spinal muscular atrophy gene.

scientific article published in May 1994

A recurrent truncating germline mutation in the BRIP1/FANCJ gene and susceptibility to prostate cancer

scientific article published on 06 January 2009

A review of prostate cancer genome wide association studies (GWAS).

scientific article

A risk prediction algorithm based on family history and common genetic variants: application to prostate cancer with potential clinical impact

scientific article published on 18 July 2011

A single-nucleotide polymorphism in the RAD51 gene modifies breast cancer risk in BRCA2 carriers, but not in BRCA1 carriers or noncarriers

scientific article published on May 2004

AA9int: SNP interaction pattern search using non-hierarchical additive model set

Abstract 4836: Gene and environment interactions of height and selected candidate SNPs in prostate cancer: results from the PRACTICAL consortium

scientific article published on 15 April 2013

Accurate prediction of BRCA1 and BRCA2 heterozygous genotype using expression profiling after induced DNA damage

scientific article published on July 2006

Accurate prediction of BRCA1 and BRCA2 heterozygous genotypes using expression profiling of lymphocytes after irradiation-induced DNA damage.

scientific article published on 13 May 2008

African-specific improvement of a polygenic hazard score for age at diagnosis of prostate cancer

scientific article published on 15 September 2020

Alcohol consumption and prostate cancer incidence and progression: A Mendelian randomisation study

scientific article published on 19 September 2016

An improved high throughput heteroduplex mutation detection system for screeningBRCA2 mutations?fluorescent mutation detection (F-MD)

scientific article published on 01 March 2001

An integrative multi-omics analysis to identify candidate DNA methylation biomarkers related to prostate cancer risk

scientific article published on 06 August 2020

Analysis of BRCA1 and BRCA2 mutations in Hungarian families with breast or breast-ovarian cancer

scientific article published in May 1997

Analysis of Over 140,000 European Descendants Identifies Genetically Predicted Blood Protein Biomarkers Associated with Prostate Cancer Risk

scientific article published on 23 July 2019

Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue

scientific article

Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data

scientific article published on 25 September 2017

Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization: Genetic variants as instruments for circulating levels

scientific article published on 26 May 2016

Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers

scientific article published on 03 July 2020

Association analyses identify 31 new risk loci for colorectal cancer susceptibility

scientific article published on 14 May 2019

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

scientific article published on 11 June 2018

Association analysis of 9,560 prostate cancer cases from the International Consortium of Prostate Cancer Genetics confirms the role of reported prostate cancer associated SNPs for familial disease

scientific article published on 26 October 2013

Association between Prostinogen (KLK15) genetic variants and prostate cancer risk and aggressiveness in Australia and a meta-analysis of GWAS data

scientific article

Association between hormonal genetic polymorphisms and early-onset prostate cancer

scientific article published in January 2005

Association between leptin receptor gene polymorphisms and early-onset prostate cancer

article

Association between polymorphisms of the GPX1 gene and second primary tumours after index squamous cell cancer of the head and neck

scientific article published on 19 April 2005

Association between the GCG polymorphism of the selenium dependent GPX1 gene and the risk of young onset prostate cancer

scientific article

Association of folate-pathway gene polymorphisms with the risk of prostate cancer: a population-based nested case-control study, systematic review, and meta-analysis

scientific article published on 25 August 2009

Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

scientific article published on 7 April 2016

Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

scholarly article published in Nature Genetics

Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

scholarly article published in Nature Genetics

Author Correction: Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia

scientific article published in Nature Communications

Author Correction: Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility

scientific article published in Nature Communications

Author Correction: Germline variation at 8q24 and prostate cancer risk in men of European ancestry

scientific article published in Nature Communications

Author Correction: Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma

scientific article published in Nature Communications

Author Correction: Large-scale transcriptome-wide association study identifies new prostate cancer risk regions

scientific article published in Nature Communications

Author Correction: The evolutionary history of lethal metastatic prostate cancer

scientific article published on 29 July 2020

BRCA1, BRCA2 and pedigree genetic analysis to determine genetic risk in the UK Royal Marsden Hospital tamoxifen prevention trial.

scientific article published on 12 March 2000

BRCA1, BRCA2 and their possible function in DNA damage response

scientific article

BRCA1/BRCA2 mutation status and analysis of cancer family history in participants of the Royal Marsden Hospital tamoxifen chemoprevention trial

article

BRCA2 is a moderate penetrance gene contributing to young-onset prostate cancer: implications for genetic testing in prostate cancer patients

scientific article published on 27 September 2011

Beyond prostate-specific antigen - future biomarkers for the early detection and management of prostate cancer

scientific article published on 07 June 2012

Blood lipids and prostate cancer: a Mendelian randomization analysis

scientific article published on 19 March 2016

CAG and GGC repeat polymorphisms in the androgen receptor gene and breast cancer susceptibility in BRCA1/2 carriers and non-carriers

scientific article published on July 2001

Circulating Metabolic Biomarkers of Screen-Detected Prostate Cancer in the ProtecT Study

scientific article published on 23 October 2018

Clinical implications of family history of prostate cancer and genetic risk single nucleotide polymorphism (SNP) profiles in an active surveillance cohort

scientific article published on 15 January 2013

Common genetic variants associated with disease from genome-wide association studies are mutually exclusive in prostate cancer and rheumatoid arthritis

scientific article published on 18 September 2012

Common variation in Kallikrein genes KLK5, KLK6, KLK12, and KLK13 and risk of prostate cancer and tumor aggressiveness

article

Comprehensive functional annotation of 77 prostate cancer risk loci

scientific article published on 30 January 2014

Correction: Rare germline variants in DNA repair genes and the angiogenesis pathway predispose prostate cancer patients to develop metastatic disease

scientific article published on 01 April 2019

Cross Cancer Genomic Investigation of Inflammation Pathway for Five Common Cancers: Lung, Ovary, Prostate, Breast, and Colorectal Cancer

scientific article

Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations

scientific article

Detection of TMPRSS2-ERG translocations in human prostate cancer by expression profiling using GeneChip Human Exon 1.0 ST arrays

scientific article

Dietary fat and early-onset prostate cancer risk

scientific article published on 19 January 2010

Diffusion-weighted MRI for detecting prostate tumour in men at increased genetic risk. ⬇️

scientific article

Effect of BRCA Mutations on Metastatic Relapse and Cause-specific Survival After Radical Treatment for Localised Prostate Cancer

scientific article published on 6 November 2014

Elevated expression of Ki-67 identifies aggressive prostate cancers but does not distinguish BRCA1 or BRCA2 mutation carriers

scientific article published on 01 February 2010

Erratum: Corrigendum: Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue

scholarly article by Colin S Cooper et al published June 2015 in Nature Genetics

Evaluating genetic risk for prostate cancer among Japanese and Latinos

scientific article

FRMD6 has tumor suppressor functions in prostate cancer

scientific article published on 28 November 2020

Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression

scientific article published on 27 March 2013

Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression.

scientific article

Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants.

scientific article published on 11 June 2018

Fine-mapping the HOXB region detects common variants tagging a rare coding allele: evidence for synthetic association in prostate cancer

scientific article

Frequent germline deleterious mutations in DNA repair genes in familial prostate cancer cases are associated with advanced disease

scientific article published on 20 February 2014

Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array

scientific article

Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array

scientific article published on 13 February 2018

Gene expression profiling after radiation-induced DNA damage is strongly predictive of BRCA1 mutation carrier status

scientific article published on February 2004

Gene promoter hypermethylation in ductal lavage fluid from healthy BRCA gene mutation carriers and mutation-negative controls

scientific article published on January 2007

Genetic determinants of telomere length and risk of common cancers: a Mendelian randomization study

scientific article

Genetic variants associated with predisposition to prostate cancer and potential clinical implications

scientific article published in April 2012

Genetic variation in prostate-specific antigen-detected prostate cancer and the effect of control selection on genetic association studies

scientific journal article

Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types

scientific article published in September 2016

Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21.

scientific article published on 4 June 2016

Genome-wide association study identifies new prostate cancer susceptibility loci

scientific journal article

Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia ⬇️

scientific article published on 9 April 2018

Genome-wide association study implicates immune dysfunction in the development of Hodgkin lymphoma

scientific article published on 07 September 2018

Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility

scientific article published in December 2017

Genome-wide association study of prostate cancer-specific survival

scientific article published on 25 August 2015

Germline BRCA mutations are associated with higher risk of nodal involvement, distant metastasis, and poor survival outcomes in prostate cancer

scientific article

Germline BRCA1 mutations increase prostate cancer risk

scientific article

Germline DNA Repair Gene Mutations in Young-onset Prostate Cancer Cases in the UK: Evidence for a More Extensive Genetic Panel

scientific article published on 15 February 2019

Germline genetic variation in prostate susceptibility does not predict outcomes in the chemoprevention trials PCPT and SELECT

scientific article published on 27 November 2019

Germline sequencing DNA repair genes in 5,545 men with aggressive and non-aggressive prostate cancer

scientific article published on 27 August 2020

Germline variants in IL4, MGMT and AKT1 are associated with prostate cancer-specific mortality: An analysis of 12,082 prostate cancer cases

scientific article published on 3 January 2018

Germline variation at 8q24 and prostate cancer risk in men of European ancestry

scientific article published in Nature Communications

Glutathione-S-transferase M1, T1 and P1 polymorphisms, and breast cancer risk, in BRCA1/2 mutation carriers

scientific article published on 27 May 2008

HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG).

scientific article published on 12 October 2012

Hand pattern indicates prostate cancer risk

scientific article

Height, selected genetic markers and prostate cancer risk: results from the PRACTICAL consortium

scientific article

Height, selected genetic markers and prostate cancer risk: results from the PRACTICAL consortium

article by Artitaya Lophatananon et al published 20 March 2018 in British Journal of Cancer

High burden of copy number alterations andc-MYCamplification in prostate cancer fromBRCA2germline mutation carriers

scholarly article by Elena Castro et al published 7 September 2015 in Annals of Oncology

High risk genes predisposing to prostate cancer development—do they exist?

Homeobox B13 G84E Mutation and Prostate Cancer Risk

scientific article published on 08 December 2018

Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor ⬇️

scientific article published on 12 June 2017

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array

scientific article

Identification of Novel Susceptibility Loci and Genes for Prostate Cancer Risk: A Transcriptome-Wide Association Study in Over 140,000 European Descendants

scientific article published on 17 May 2019

Identification of a novel prostate cancer susceptibility variant in the KLK3 gene transcript

scientific article

Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma

scientific article published in Nature Communications

Identification of new genetic risk factors for prostate cancer

scientific article published on December 2008

Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14

scientific article published on 12 May 2013

Identification of seven new prostate cancer susceptibility loci through a genome-wide association study

scientific article

Implications of polygenic risk-stratified screening for prostate cancer on overdiagnosis

scientific article published on 8 January 2015

Increased level of chromosomal damage after irradiation of lymphocytes from BRCA1 mutation carriers

scientific article published on January 2006

Integration of ERG gene mapping and gene-expression profiling identifies distinct categories of human prostate cancer

scientific article published on 25 November 2008

Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions

scientific article

Interim Results from the IMPACT Study: Evidence for Prostate-specific Antigen Screening in BRCA2 Mutation Carriers

scientific article published on 16 September 2019

Investigating the possible causal role of coffee consumption with prostate cancer risk and progression using Mendelian randomization analysis

scientific article published on 14 October 2016

Large-scale Analysis Demonstrates Familial Testicular Cancer to have Polygenic Aetiology

scientific article published on 21 June 2018

Large-scale transcriptome-wide association study identifies new prostate cancer risk regions

scientific article published in Nature Communications

Linkage mapping of the spinal muscular atrophy gene

scientific article published on 01 March 1994

LocusExplorer: a user-friendly tool for integrated visualization of human genetic association data and biological annotations

scientific article

Loss of heterozygosity at the BRCA1 and BRCA2 loci detected in ductal lavage fluid from BRCA gene mutation carriers and controls

scientific article published in July 2006

Lymphocyte radiosensitivity inBRCA1 andBRCA2 mutation carriers and implications for breast cancer susceptibility

Molecular mechanisms in the antiproliferative action of taxol and tiazofurin

scientific article published in September 1996

Multi-stage genome-wide association study identifies new susceptibility locus for testicular germ cell tumour on chromosome 3q25 ⬇️

scientific article

Multiple loci on 8q24 associated with prostate cancer susceptibility

scientific article published on 20 September 2009

Multiple loci with different cancer specificities within the 8q24 gene desert

scientific article

Multiple newly identified loci associated with prostate cancer susceptibility

scientific article

Multiple novel prostate cancer predisposition loci confirmed by an international study: the PRACTICAL Consortium

scientific article

Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

scientific article published on 29 May 2015

Mutation analysis of the MSMB gene in familial prostate cancer

scientific article

Overexpression of RAD51 occurs in aggressive prostatic cancer

scientific article

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

scientific article published in December 2016

Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts

scientific article published on 10 January 2018

Polygenic risk-tailored screening for prostate cancer: A benefit-harm and cost-effectiveness modelling study

scientific article published on 20 December 2019

Polyglutamine repeat length in theAIB1 gene modifies breast cancer susceptibility inBRCA1 carriers

article

Polyunsaturated fatty acids and prostate cancer risk: a Mendelian randomisation analysis from the PRACTICAL consortium

scientific article published on 4 August 2016

Post hoc Analysis for Detecting Individual Rare Variant Risk Associations Using Probit Regression Bayesian Variable Selection Methods in Case-Control Sequencing Studies

scientific article published on 17 June 2016

Prediction of individual genetic risk to prostate cancer using a polygenic score

scientific article published on 14 July 2015

Prevalence of the HOXB13 G84E germline mutation in British men and correlation with prostate cancer risk, tumour characteristics and clinical outcomes

scientific article published on 16 January 2015

Prostate Cancer Germline Variations and Implications for Screening and Treatment

scientific article

Prostate cancer in BRCA2 germline mutation carriers is associated with poorer prognosis.

scientific article

Prostate cancer in male BRCA1 and BRCA2 mutation carriers has a more aggressive phenotype

scientific article published on 8 January 2008

Prostate cancer risk regions at 8q24 and 17q24 are differentially associated with somatic TMPRSS2:ERG fusion status

scientific article

Prostate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition

scientific article published on 4 January 2018

Prostate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition.

scientific article

Pubertal development and prostate cancer risk: Mendelian randomization study in a population-based cohort

scientific article published on 4 April 2016

Publisher Correction: Shared heritability and functional enrichment across six solid cancers

scientific article published on 23 September 2019

REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants

scientific article published on 21 September 2016

Rare germline variants in DNA repair genes and the angiogenesis pathway predispose prostate cancer patients to develop metastatic disease

article

Reducing GWAS Complexity

scientific article

Relationship between glutathione S-transferase M1, P1 and T1 polymorphisms and early onset prostate cancer

scientific article published in June 2001

Relationship between glutathione S-transferase M1, T1, and P1 polymorphisms and chronic lymphocytic leukemia

scientific article

Relationship of self-reported body size and shape with risk for prostate cancer: A UK case-control study

scientific article published on 17 September 2020

Reply to Xiaoling Lin, Brian T. Helfand, and Jianfeng Xu's Letter to the Editor re: Daniel A. Leongamornlert, Edward J. Saunders, Sarah Wakerell, et al. Germline DNA Repair Gene Mutations in Young-onset Prostate Cancer Cases in the UK: Evidence for

scientific article published on 22 June 2019

Reply: ‘Hand pattern indicates risk of prostate cancer’

article by A A Rahman et al published July 2011 in British Journal of Cancer

Ribonucleases from rat and bovine liver: purification, specificity and structural characterization ⬇️

scientific article published on April 23, 1998

Risk Analysis of Prostate Cancer in PRACTICAL Consortium--Response

scientific article published on January 2016

Risk Analysis of Prostate Cancer in PRACTICAL, a Multinational Consortium, Using 25 Known Prostate Cancer Susceptibility Loci

scientific article published on 2 April 2015

Role of Engrailed-2 (EN2) as a prostate cancer detection biomarker in genetically high risk men.

scientific article published in January 2013

Runs of homozygosity and testicular cancer risk

scientific article published on 01 July 2019

Screening for prostate cancer: the way ahead

scientific article

Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets

scientific article published on 16 April 2018

Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study

scientific article

Shared heritability and functional enrichment across six solid cancers

scientific article published in Nature Communications

Shared heritability and functional enrichment across six solid cancers

Structural determinants of the uridine-preferring specificity of RNase PL3.

scientific article

Targeted prostate cancer screening in BRCA1 and BRCA2 mutation carriers: results from the initial screening round of the IMPACT study

scientific article

Targeted prostate cancer screening in men with mutations in BRCA1 and BRCA2 detects aggressive prostate cancer: preliminary analysis of the results of the IMPACT study

scientific article published on 14 September 2010

Telomere length shows no association with BRCA1 and BRCA2 mutation status

scientific article published on 29 January 2014

Telomere structure and maintenance gene variants and risk of five cancer types

scientific article published on 15 December 2016

The CHEK2 Variant C.349A>G Is Associated with Prostate Cancer Risk and Carriers Share a Common Ancestor

scientific article published on 04 November 2020

The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers

scientific article published on 03 October 2016

The PROFILE Feasibility Study: Targeted Screening of Men With a Family History of Prostate Cancer

scientific article published on 05 May 2016

The carrier clinic: an evaluation of a novel clinic dedicated to the follow-up of BRCA1 and BRCA2 carriers--implications for oncogenetics practice

scientific article published on 14 May 2010

The contribution of rare variation to prostate cancer heritability

scientific article

The effect of sample size on polygenic hazard models for prostate cancer

scientific article published on 08 June 2020

The effects of height and BMI on prostate cancer incidence and mortality: a Mendelian randomization study in 20,848 cases and 20,214 controls from the PRACTICAL consortium

scientific article

The evolutionary history of lethal metastatic prostate cancer

scientific article published on April 2015

The genetic epidemiology of prostate cancer and its clinical implications

scientific article published on 03 December 2013

The potential value of microseminoprotein-beta as a prostate cancer biomarker and therapeutic target

scientific article

The rs10993994 risk allele for prostate cancer results in clinically relevant changes in microseminoprotein-beta expression in tissue and urine

scientific article published in 2010

Translating genetic risk factors for prostate cancer to the clinic: 2013 and beyond

scientific article published on January 2014

Two percent of men with early-onset prostate cancer harbor germline mutations in the BRCA2 gene

scientific article

Two-stage Study of Familial Prostate Cancer by Whole-exome Sequencing and Custom Capture Identifies 10 Novel Genes Associated with the Risk of Prostate Cancer

scientific article published on 13 August 2020

Use of a Novel Nonparametric Version of DEPTH to Identify Genomic Regions Associated with Prostate Cancer Risk

scientific article published on 18 August 2016

Validation of loci at 2q14.2 and 15q21.3 as risk factors for testicular cancer

scientific article published on 7 December 2017

Validation of prostate cancer risk-related loci identified from genome-wide association studies using family-based association analysis: evidence from the International Consortium for Prostate Cancer Genetics (ICPCG)

scientific article published on 25 December 2011

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